检索结果-南通市图书馆

Significance of margin in nephron sparing surgery for renal cell carcinoma of 4 cm or less

Chinese Medical Journal 2008年第17期121卷 1662-1665页

作者： LI Quan-lin guan hong-wei WANG Fa-peng JIANG Tao WU hong-chang SONG Xi-shuang Department of Urology Department of Pathology

Background Current surgical practice for nephron sparing surgery allows at least 1 cm margin of normal tissue around the tumour. However, recent studies show that the width of the margin is not important, even simple enucleation is as effective as partial nephrectomy. We explored whether margin size has significant impacts on clinical outcomes in nephron sparing surgery for renal cell carcinoma of 4 cm or less. Methods Between 1998 and 2006, 115 patients with sporadic, pathologically confirmed, renal cell carcinoma 4 cm or less （Tla） and normal contralateral kidney were treated by nephron sparing surgery using a margin less than 5 mm. The surgical margin status was evaluated from frozen and permanent paraffin sections. Results Mean and median tumour diameter were 3.3 cm and 3.5 cm （range 1.0-4.0）. The mean margin width was 2.2 mm （median 2.0, range 0-6）. In addition, 114 cases had margins 5 mm or less （99.1%）, 97 cases （84.3%） had margin 3 mm or less, and 26 cases had margin zero （22.6%）. None of the patients had positive surgical margins. No patients died during follow-up （mean 65 months）. There were no any major surgical complications and no distant metastasis was detected. Local recurrence was detected in one case （0.9%） at a different site of the kidney. Conclusions For early localized renal cell carcinoma of 4 cm or less, as long as tumour is completely excised, the size of margin in nephron sparing surgery is not important. Nephron sparing surgery with 5 mm margin is enough for tumour control. It provides excellent renal function preservation, favourable long term progression free survival and is not associated with an increased risk of local recurrence.

关键词： renal cell carcinoma partial nephrectomy nephron sparing surgery surgical margin follow-up studies

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Synthesis and Improved Acetone Sensing Properties of Porous α-Fe_(2)O_(3) Nanowires

引用

Chinese Physics Letters 2013年第2期30卷 49-53页

作者： LIU Li CHI Xiao WANG Guo-guang LIU Chang-Bai SHAN Hao ZHANG Xiao-Bo WANG Lian-Yuan guan hong-Yu State Key Laboratory of Superhard Materials College of PhysicsJilin UniversityChangchun 130012 College of Electronic Science and Engineering Jilin UniversityChangchun 130012 College of Chemistry Northeast Normal UniversityChangchun 130026

Porousα-Fe_(2)O_(3) nanowires are synthesized by a simple wet chemical method with a precursor of peroxyacetyl nitrate(PAN),andα-Fe_(2)O_(3) nanoparticles are also synthesized in the same way except for the addition of *** sensors are fabricated by coating the samples on ceramic tubes with Au signal electrodes and Ni-Cr heaters.A sensing investigation reveals that the porousα-Fe_(2)O_(3) nanowires have a higher sensitivity compared toα-Fe_(2)O_(3) nanoparticles at 260℃.The corresponding sensor response(R_(a)/R_(g))is 18.2 at the maximum to 100 ppm acetone,and the response and recovery times are about 8 and 12 s,*** porous and one-dimensional nanostructures of the porousα-Fe_(2)O_(3) nanowires benefit for the gas-absorption and electrical-signal-transfer,and thus improve the sensor sensitivity consequentially.

关键词： nanowires Porous porous

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

CShaperApp:Segmenting and analyzing cellular morphologies of the developing Caenorhabditis elegans embryo

引用

Quantitative Biology 2024年第3期12卷 329-334页

作者： Jianfeng Cao Lihan Hu Guoye guan Zelin Li Zhongying Zhao Chao Tang hong Yan Department of Electrical Engineering City University of Hong KongHong KongChina Centre for Intelligent Multidimensional Data Analysis Limited Hong KongChina College of Computer and Information Hohai UniversityNanjingChina Center for Quantitative Biology Peking UniversityBeijingChina Department of Biology Hong Kong Baptist UniversityHong KongChina State Key Laboratory of Environmental and Biological Analysis Hong Kong Baptist UniversityHong KongChina Peking-Tsinghua Center for Life Sciences Peking UniversityBeijingChina School of Physics Peking UniversityBeijingChina

Caenorhabditis elegans has been widely used as a model organism in developmental biology due to its invariant *** this study,we developed a desktop software CShaperApp to segment fluorescence-labeled images of cell membranes and analyze cellular morphologies interactively during *** *** on the previously proposed framework CShaper,CShaperApp empowers biologists to automatically and efficiently extract quantitative cellular morphological data with either an existing deep learning model or a fine-tuned one adapted to their in-house *** results show that it takes about 30 min to process a three-dimensional time-lapse(4D)dataset,which consists of 150 image stacks at a~1.5-min interval and covers *** embryogenesis from the 4-cell to 350-cell *** robustness of CShaperApp is also validated with the datasets from different ***,modularized implementation increases the flexibility in multi-task applications and promotes its flexibility for future *** cell morphology over development has emerged as a focus of interest in developmental biology,CShaperApp is anticipated to pave the way for those studies by accelerating the high-throughput generation of systems-level quantitative data *** software can be freely downloaded from the website of Github(cao13jf/CShaperApp)and is executable on Windows,macOS,and Linux operating systems.

关键词： C.elegans embryogenesis cellular morphology cellular segmentation deep learning desktop software

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Dynamics of fluid and heat flow in a CO_2-based injection-production geothermal system

引用

Journal of Groundwater Science and Engineering 2016年第4期4卷 377-388页

作者： FENG guan-hong XU Tian-fu ZHU Hui-xing Key Laboratory of Groundwater Resources and Environment Ministry of Education Jilin University

CO_2 is now considered as a novel heat transmission fluid to extract geothermal energy. It can be used for both energy exploitation and CO_2 geological sequestration. Here, a 3-D, "two-spot" pattern well model is developed to analyze the mechanism of CO_2-water displacement and heat extraction. To obtain a deeper understanding of CO_2-geothermal system under some more realistic conditions, heterogeneity of reservoir's hydrological properties is taken into account. Due to the fortissimo mobility of CO_2, as long as the existence of highly permeable zone between the two wells, it is more likely to flow through the highly permeable zone to reach the production well, even though the flow path is longer. The preferential flow shortens circulation time and reduces heat-exchange area, probably leading to early thermal breakthrough, which makes the production fluid temperature decrease rapidly. The analyses of flow dynamics of CO_2-water fluid and heat may be useful for future design of a CO_2-based geothermal development system.

关键词： Binary system CO2-water displacement Heterogeneity Preferential flow

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Low-Cost Posture Recognition of Moving Hands by Profile-Mold Construction in Cluttered Background and Occlusion

引用

Journal of Signal and Information Processing 2018年第4期9卷 258-265页

作者： Din-Yuen Chan guan-hong Lin Xi-Wen Wu Department of Computer Science and Information Engineering National Chiayi University Taiwan

In this paper, we propose a low-cost posture recognition scheme using a single webcam for the signaling hand with nature sways and possible oc-clusions. It goes for developing the untouchable low-complexity utility based on friendly hand-posture signaling. The scheme integrates the dominant temporal-difference detection, skin color detection and morphological filtering for efficient cooperation in constructing the hand profile molds. Those molds provide representative hand profiles for more stable posture recognition than accurate hand shapes with in effect trivial details. The resultant bounding box of tracking the signaling molds can be treated as a regular-type object-matched ROI to facilitate the stable extraction of robust HOG features. With such commonly applied features on hand, the prototype SVM is adequately capable of obtaining fast and stable hand postures recognition under natural hand movement and non-hand object occlusion. Experimental results demonstrate that our scheme can achieve hand-posture recognition with enough accuracy under background clutters that the targeted hand can be allowed with medium movement and palm-grasped object. Hence, the proposed method can be easily embedded in the mobile phone as application software.

关键词： Bounding Box Hand Profile Mold Motion-Hand Posture Recognition

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research progress on the development of hepatocyte growth factor/c-Met signaling pathway in gastric cancer:A review

引用

World Journal of Gastrointestinal Oncology 2024年第8期16卷 3397-3409页

作者： Wu-Jie Wei Ya-Li hong Yi Deng guan-Liang Wang Jiang-Tao Qiu Fang Pan Department of Oncology People's Hospital of Chongqing HechuanChongqing 401520China Department of Cardiovascular People's Hospital of Chongqing HechuanChongqing 401520China Intensive Care Unit People's Hospital of Chongqing HechuanChongqing 401520China Department of Gastrointestinal Surgery Beijing Tsinghua Changgung HospitalBeijing 100084China

Hepatocyte growth factor(HGF)and its receptor,c-Met,play important roles in the occurrence,development,and treatment of gastric cancer(GC).This review explored the function of the HGF/c-Met signaling pathway in GC and its potential targeted therapeutic *** one of the most common malignant tumors worldwide,GC has a complex pathogenesis and limited therapeutic ***,a thorough understanding of the molecular mechanism of GC is very important for the development of new therapeutic *** HGF/c-Met signaling pathway plays an important role in the proliferation,migration,and invasion of GC cells and has become a new therapeutic *** review summarizes the current research progress on the role of HGF/c-Met in GC and discusses targeted therapeutic strategies targeting this signaling pathway,providing new ideas and directions for the treatment of GC.

关键词： Targeted therapy Hepatocyte growth factor c-Met Gastric cancer Prognosis assessment Review

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Sorption Behavior of Am(Ⅲ) on Granite

Sorption Behavior of Am(Ⅲ) on Granite

引用

作者： ZHOU Duo LONG Hao-qi guan hong-zhi

The formation of Am(Ⅲ) colloid in pure water/ultrafiltrated groundwater/groundwater was studied with the variation of pH,ionic strength,americium concentration,concentration of saltsodium sulfate and concentration of sodasodium *** results show that the colloid in water is an intrinsic Am(Ⅲ) colloid,the fraction of Am(Ⅲ) ions is larger than the fraction of Am(Ⅲ) colloid in ultrafiltrated groundwater,the fraction of Am(Ⅲ) ions and the fraction of Am(Ⅲ) colloid decreased with time in *** formation of Am(Ⅲ) colloid is influenced strongly by pH,ionic *** fraction of Am(Ⅲ) colloid decreases with original concentration of soda sodium bicarbonate increased in *** fraction of Am(Ⅲ) colloid increases with original concentration of saltsodium sulfate increased

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

The Indications of Elective Nephron Sparing Surgery For Renal Cell Carcinoma

The Indications of Elective Nephron Sparing Surgery For Rena...

引用

第十五届全国泌尿外科学术会议

作者： Li Quan-lin guan hong-wei Jiang Tao 大连医科大学附属第一医院泌尿外科

Background: Nephron sparing surgery (NSS) has been more and more established as an alternative treatment to radical nephrectomy for small renal tumors in patients with a healthy contralateral kidney (elective NSS). Ho...

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

不同临床设计的ERA附着体义齿修复下颌牙列游离端缺损的三维有限元分析

引用

实用口腔医学杂志 2017年第1期33卷 95-99页

作者：李晓娜刘洋 hong guan 大连市口腔医院特诊科 116021 大连市口腔医院口腔修复科 116021 School of Engineering Griffith UniversityGold Coast Campus

目的:研究3种不同临床设计ERA附着体义齿修复下颌远中游离端缺损的应力及位移分布。方法:建立ERA附着体义齿修复下颌远中游离端缺损的三维有限元模型,根据临床设计分为基本组、支托组和跨弓组。应用有限元法研究在垂直及45°斜向2种载... 详细信息

目的:研究3种不同临床设计ERA附着体义齿修复下颌远中游离端缺损的应力及位移分布。方法:建立ERA附着体义齿修复下颌远中游离端缺损的三维有限元模型,根据临床设计分为基本组、支托组和跨弓组。应用有限元法研究在垂直及45°斜向2种载荷方向100 N的作用下,基牙及基托下黏膜的应力和位移以及基托的位移情况。结果:2种载荷下3组模型均在远中基牙远中邻面肩台出现应力集中,远中基牙预备体咬合面位移最大,支托组基牙位移最大,分别为14.91μm和63.09μ.m,其次为基本组(9.38μm和50.56μm),跨弓组最小(8.85μm和47.31μm)。结论:在本研究条件下,为远中游离端牙列缺损设计基本的ERA附着体义齿更趋于合理。

关键词：有限元分析(FE) 局部义齿 ERA附着体应力

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Therapeutic Effect of Rhodopseudomonas palustris-Bioconverted Extract of Lycium barbarum on Rats with Lead Exposure

引用

Biomedical and Environmental Sciences 2024年第4期37卷 440-444页

作者： YANG hong SUN Yi CHAI Shu Tong LIANG Yan Hui LIU Ya Ni YANG guan E School of Pharmacy Shanxi Medical UniversityTaiyuan 030001ShanxiChina

Lead is a ubiquitous pollutant and Pb pollution is a global public health *** has been reported to induce multiple adverse effects,including reproductive toxicity,neurotoxicity,carcinogenicity,nephrotoxicity,immunotoxicity,and hypertension[1].The traditional medical treatment available for Pb poisoning is chelation,which can save lives in individuals with very high blood Pb *** commonly used chelating agents include CaNa2EDTA and meso-2,3-dimercaptosuccinic ***,chelation therapy has strong short-term effects on the overall long-term management of Pb exposure.

关键词： converted chelation chelating

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：