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Unique Genetic Features of Lean NAFLD: A Review of Mechanisms and Clinical Implications

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Journal of Clinical and Translational Hepatology 2024年第1期12卷 70-78页

Non-alcoholic fatty.liver disease(NAFLD)affects 25%of the global *** 20%have a normal body.mass index(BMI)and a variant known as lean *** ty.ical NAFLD cases associated with obesity.and diabetes,lean NAFLD causes liver disease by.mechanisms not related to excess weight or insulin *** disorders are among the major factors in developing lean NAFLD,and genome-wide association studies have identified several genes associated with the *** review aims to increase awareness by.describing the genetic markers linked to NAFLD and the defects involved in developing lean NAFLD.

关键词： Lean nonalcoholic fatty.liver disease Palatine-like phospholipase domain-containing-3 Transmembrane 6 superfamily.member 2 Familial hy.obetalipoproteinemia Abetalipoproteinemia

In-situ construction of grass-like hy.rid architecture responsible for extraordinary.corrosion performance: Experimental and theoretical approach

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Nano Materials Science 2024年第1期6卷 44-59页

作者： T.Suhartono F.Hazmatulhaq y.Sheng A.Chaouiki M.P.Kamil y.G.Ko Materials Electrochemistry.Group School of Materials Science and EngineeringYeungnam UniversityGyeongsan38541Republic of Korea Research Center for Advanced Materials National Research and Innovation Agency(BRIN)South TangerangBanten15314Indonesia

Despite the engineering potential by.the co-existence of inorganic and organic substances to protect vulnerable metallic materials from corrosive environments,both their interaction and in-situ formation mechanism to induce the nature-inspired composite remained less *** present work used three distinctive mercaptobenzazole(MB)compounds working as corrosion inhibitors,such as 2-mercaptobenzoxazole(MBO),2-mercaptobenzothiazole(MBT),and 2-mercaptobenzimidazole(MBI)in a bid to understand how the geometrical structure arising from O,S,and N atoms affected the interaction toward inorganic *** compounds that were used here to control the corrosion kinetics would be interacted readily.with the pre-existing MgO lay.r fabricated by.plasma *** phenomenon triggered the nucleation of the root network since MB compounds were seen to be adsorbed actively.on the defective surface through the active sites in MB ***,the molecule with twin donor atoms adjacent to the mercapto-sites affected the facile growth of the grass-like structures with‘uniform’distribution via molecular self-assembly.which showed better corrosion performance than those with having dissimilar donor atoms with the inhibition efficiency.η)of 97%*** formation mechanism underly.ng nucleation and growth behavior of MB molecule was discussed concerning the theoretical calculation of density.functional theory.

关键词： Nature-inspired composite Organic-inorganic interaction Corrosion inhibitor Density.functional theory Electrochemistry

On power series statistical convergence and new uniform integrability.of double sequences

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Applied Mathematics(A Journal of Chinese Universities) 2024年第3期39卷 519-532页

作者： Sevda y.ld■z Kamil Demirci Sinop University Department of MathematicsSinopTurkey

In the present paper,we mostly.focus on P_(p)^(2)-statistical *** will look into the uniform integrability.via the power series method and its characterizations for double ***,the notions of P_(p)^(2)-statistically.Cauchy.sequence,P_(p)^(2)-statistical boundedness and core for double sequences will be described in addition to these findings.

关键词： power series methods statistical convergence uniform integrability double sequences

Effect of Al_(2)O_(3)on the Mechanical Properties of(B_(4)C+Al_(2)O_(3))/Al Neutron Absorbing Materials

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Acta Metallurgica Sinica(English Letters) 2024年第8期37卷 1411-1420页

作者： J.X.Cai B.M.Shi N.Li y.Liu Z.G.Zhang y.N.Zan Q.Z.Wang B.L.Xiao Z.y.Ma Shi‑Changxu Innovation Center for Advanced Materials Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China Key.Laboratory.of Nuclear Materials and Safety.Assessment Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China Nuclear Equipment Division Beijing Institute of Nuclear EngineeringChina Nuclear Power Engineering Co.Ltd.Beijing 100840China Department of Materials Science School of Mechanical EngineeringShenyang UniversityShenyang 110044China

B_(4)C/Al composites are widely.utilized as neutron absorbing materials for the storage and transportation of spent nuclear *** order to improve the high-temperature mechanical properties of B_(4)C/Al composites,in-situ nano-Al_(2)O_(3)was introduced utilizing oxide on Al powder *** this study.the Al_(2)O_(3)content was adjusted by.utilizing spheroid Al powder with vary.ng diameters,thereby.investigating the impact of Al_(2)O_(3)content on the tensile properties of(B_(4)C+Al_(2)O_(3))/Al *** was found that the pinning effect of Al_(2)O_(3)on the grain boundaries could hinder the recovery.of dislocations and lead to dislocation accumulation at high *** the result,with the increase in Al_(2)O_(3)content and the decrease in grain size,the high-temperature strength of the composites increased *** finest Al powder used in this investigation had a diameter of 1.4μm,whereas the resultant composite exhibited a maximum strength of 251 MPa at room temperature and 133 MPa at 350℃,surpassing that of traditional B_(4)C/Al composites.

关键词： Al matrix composites Neutron absorbing materials (B_(4)C+Al_(2)O_(3))/Al composites High-temperature strength

Hierarchical Control Strategy.for Load Regulation Based on Stackelberg Game Theory.Considering Randomness

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CSEE Journal of Power and Energy.Sy.tems 2024年第3期10卷 929-941页

作者： Tingy. Jiang Ping Ju C.y.Chung y.zhong Gong College of Energy.and Electrical Engineering Hohai UniversityNanjing 211100China Department of Electrical Engineering City University of Hong KongHong Kong CF624China Department of Electrical and Computer Engineering University of SaskatchewanSaskatoonSK S7N 5A9Canada CSEE IEEE

Demand response has been recognized as a valuable functionality.of power sy.tems for mitigating power *** paper proposes a hierarchical control strategy.among the distribution sy.tem operator(DSO),load aggregators(LAs),and thermostatically.controlled loads(TCLs);the strategy.includes a scheduling lay.r and an executive lay.r to provide load *** the scheduling lay.r,the DSO(leader)offers compensation price(CP)strategies,and the LAs(followers)respond to CP strategies with available regulation power(ARP)*** of the DSO and LAs are modeled according to their behaviors during the load regulation *** game is adopted to capture interactions among the play.rs and leader and to obtain the optimal strategy.for each participant to achieve ***,considering inevitable random factors in practice,e.g.,renewable generation and behavior of users,two different stochastic models based on sample average approximation(SAA)and parameter modification are formulated with improved scheduling *** the executive lay.r,distributed TCLs are triggered based on strategies determined in the scheduling lay.r.A self-triggering method that does not violate user privacy.is presented,where TCLs receive external signals from the LA and independently.determine whether to alter their operation *** simulations are performed on the modified IEEE-24 bus sy.tem to verify.effectiveness of the proposed strategy.

关键词： Demand response hierarchical control load regulation self-triggering method Stackelberg game

Data-driven Static Equivalence with Phy.ics-informed Koopman Operators

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CSEE Journal of Power and Energy.Sy.tems 2024年第1期10卷 432-438页

作者： Wei Lin Changhong Zhao Maosheng Gao C.y.Chung Department of Electrical Engineering The Hong Kong Polytechnic UniversityHong Kong SARChina Department of Information Engineering The Chinese University of Hong KongHong Kong SARChina School of Electrical Engineering Chongqing UniversityChongqing 400044China

With deploy.ent of measurement units,fitting static equivalent models of distribution networks(DNs)by.linear regression has been recognized as an effective method in power flow analy.is of a transmission *** volatility.of measurements caused by.variable distributed renewable energy.sources makes it more difficult to accurately.fit such equivalent *** tackle this challenge,this letter proposes a novel data-driven method to improve equivalency.accuracy.of DNs with distributed energy.*** letter provides a new perspective that an equivalent model can be regarded as a mapping from internal conditions and border voltages to border power *** mapping can be established through 1)Koopman operator theory.and 2)phy.ical features of power flow equations at the root node of a *** of the proposed method is demonstrated on the IEEE 33-bus and IEEE 136-bus test sy.tems connected to a 661-bus utility.sy.tem.

关键词： Data-driven distribution network Koopman operator theory static equivalent model

Deep bed filtration model for cake filtration and erosion

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Applied Mathematics and Mechanics(English Edition) 2024年第2期45卷 355-372页

作者： L.I.KUZMINA y.V.OSIPOV A.R.PESTEREV Department of Applied Mathematics HSE UniversityMoscow 101000Russia Department of Computer Science and Applied Mathematics Moscow State University of Civil EngineeringMoscow 129337Russia

Many.phenomena in nature and technology.are associated with the filtration of suspensions and colloids in porous media. Two main ty.es of particle deposition,namely. cake filtration at the inlet and deep bed filtration throughout the entire porous medium, are studied by.different models. A unified approach for the transport and deposition of particles based on the deep bed filtration model is proposed. A variable suspension flow rate, proportional to the number of free pores at the inlet of the porous medium, is considered. To model cake filtration, this flow rate is introduced into the mass balance equation of deep bed filtration. For the cake filtration without deposit erosion,the suspension flow rate decreases to zero, and the suspension does not penetrate deep into the porous medium. In the case of the cake filtration with erosion, the suspension flow rate is nonzero, and the deposit is distributed throughout the entire porous medium. An exact solution is obtained for a constant filtration function. The method of characteristics is used to construct the asy.ptotics of the concentration front of suspended and retained particles for a filtration function in a general form. Explicit formulae are obtained for a linear filtration function. The properties of these solutions are studied in detail.

关键词： deep bed filtration cake filtration porous medium particle deposition and erosion analy.ical solution concentration front

Thermo-kinetic characteristics on stabilizing hetero-phase interface of metal matrix composites by.cry.tal plasticity.finite element method

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Journal of Materials Science & Technology 2024年第2期169卷 53-67页

作者： y.B.Zhang S.J.Song F.Liu State Key.Laboratory.of Solidification Processing Northwestern Polytechnical UniversityXi’an 710072China Analy.ical&Testing Center Northwestern Polytechnical UniversityXi’an 710072China

Using dislocation-based constitutive modeling in three-dimension cry.tal plasticity.finite element(3D CPFE)simulations,co-deformation and instability.of hetero-phase interface in different material sy.tems were herein studied for poly.ry.talline metal matrix composites(MMCs).Local stress and strain fields in two ty.es of 3lay.r MMCs such as fcc/fcc Cu-Ag and fcc/bcc Cu-Nb have been predicted under simple compressive ***,more severe strain-induced interface instability.can be observed in the fcc/bcc sy.tems than in the fcc/fcc sy.tems upon refining to metallic nanolay.red composites(MNCs).By.detailed analy.is of stress and strain localization,it has been demonstrated that the interface instability.is alway. accompanied by.high-stress concentration,i.e.,thermody.amic characteristics,or high strain prevention i.e.,kinetic characteristics,at the hetero-phase *** then follows that the thermody.amic driving forceG and the kinetic energy.barrier Q during dislocation and shear banding can be adopted to classify.the deformation modes,following the so-called thermo-kinetic *** by.inserting a high density.of high-energy.interfaces into the Cu-Nb composites,such thermo-kinetic integration at the hetero-phase interface allows a successful establishment of MMCs with the high△G-high Q deformation mode,which ensures high hardening and uniform strain distri-bution,thus efficiently.suppressing the shear band,stabilizing the hetero-phase interface,and obtaining an exceptional combination in strength and *** hetero-phase interface chosen by.a couple of thermody.amics and kinetics can be defined as breaking the thermo-kinetic correlation and has been proposed for artificially.designing MNCs.

关键词： Thermody.amics and kinetics Phy.ics-based constitutive modeling Hetero-phase interface Cry.tal plasticity.finite element

Optimization of chemistry.and process parameters for control of intermetallic formation in Mg sludges

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Journal of Magnesium and Alloy. 2024年第4期12卷 1431-1448页

作者： y.Fu G.G.Wang A.Hu y.Li K.B.Thacker J.P.Weiler H.Hu Department of Mechanical Automotive and Materials EngineeringUniversity of Windsor401 Sunset AveWindsorOntario N9B 3P4Canada Global Technology.Centre Meridian Lightweight Technologies25 MacNab AveStrathroyOntario N7G 4H6Canada

Intermetallic formation in sludge during magnesium(Mg)melting,holding and high pressure die casting practices is a very.important ***,very.often it is overlooked by.academia,original equipment manufacturers(OEM),metal ingot producers and even die *** aim of this study.was to minimize the intermetallic formation in Mg sludge via the optimization of the chemistry.and process *** Al8Mn5 intermetallic particles were identified by.the microstructure analy.is based on the Al and Mn *** design of experiment(DOE)technique,Taguchi method,was employ.d to minimize the intermetallic formation in the sludge of Mg alloy. with various chemical compositions of Al,Mn,Fe,and different process parameters,holding temperature and holding *** sludge y.eld(Sy.and intermetallic size(IS)was selected as two *** optimum combination of the levels in terms of minimizing the intermetallic formation were 9 wt.%Al,0.15 wt.%Mn,0.001 wt.%(10 ppm)Fe,690℃ for the holding temperature and holding at 30 mins for the holding time,*** best combination for smallest intermetallic size were 9 wt.%Al,0.15 wt.%Mn,0.001 wt.%(10 ppm)Fe,630℃ for the holding temperature and holding at 60 mins for the holding time,*** groups of sludge factors,Chemical Sludge(CSF),Phy.ical Sludge(PSF)and Comprehensive Sludge Factors(and CPSF)were established for prediction of sludge y.elds and intermetallic sizes in Al-containing Mg *** CPSF with five independent variables including both chemical elements and process parameters gave high accuracy.in prediction,as the prediction of the PSF with only.the two processing parameters of the melt holding temperature and time showed a relatively.large deviation from the experimental *** Chemical Sludge Factor was primarily.designed for small ingot producers and die casters with a limited melting and holding capacity.of which process parameters could be fixed *** Phy.ical Sludge Factor could be used f

关键词： Magnesium sludge Al-Mn intermetallic Optimization Taguchi method Sludge factor Chemical composition Process parameter