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Chinese Chemical Letters 2024年第8期35卷 93-100页

作者： Aolei tan.Xiaoxiao ma Department of Precision Instrument Tsinghua UniversityBeijing 100084China

Metabolism encompasses a series of intricate biochemical processes that are vital for the sustenance of life in ***,an essential scientific discipline,is a field of study within the broader domain of systems biology that focuses on the comprehensive analysis of small molecules,known as metabolites including lipids,coenzymes,etc.,which are synthesized during *** the contin-uous development of metabolomics,the multiple biological functions of metabolites are constan.ly being discovered,encompassing signal transduction and enzyme stimulation,while concurrently exhibiting as-sociations with afflictions like cancer and *** comprehension of metabolite functionalities and their intricate interplay with disease conditions assumes paramount importan.e in both disease-focused research endeavors and the development of diagnostic *** scholarly exposition undertakes an ex-tensive review of recent advancements in the investigation of functional roles assumed by metabolites,with specific emphasis on metabolites in lipid synthesis,glucose metabolism and exogenous metabolites.

关键词： Metabolites Small molecules Biological functions Physiological processes Diseases

Requirements ranking based on crowd-sourcing high-end product USs

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Journal of Systems Engineering and Electronics 2024年第1期35卷 94-104页

作者： ma Yufeng DOU Yajie XU Xiangqian JIA Qingyang tan.Yuejin College of Systems Engineering National University of Defense TechnologyChangsha 410003China

Based on the characteristics of high-end products,crowd-sourcing user stories can be seen as an effective means of gathering requirements,involving a large user base and generating a substan.ial amount of unstructured *** key challenge lies in transforming abstract user needs into specific ones,requiring integration and ***,we propose a topic mining-based approach to categorize,summarize,and rank product requirements from user ***,after determining the number of story categories based on py LDAvis,we initially classify“I want to”phrases within user ***,classic topic models are applied to each category to generate their names,defining each post-classification user story category as a ***,a weighted ranking function is devised to calculate the importan.e of each ***,we validate the effectiveness and feasibility of the proposed method using 2966 crowd-sourced user stories related to smart home systems.

关键词： high-end product complex system crowd-sourcing user stories topic mining requirements ranking

High performance photodetector based on few-layer MoTe_(2)/CdS_(0.42)Se_(0.58) flake heterojunction

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Frontiers of physics 2024年第4期19卷 91-101页

作者： Ran ma Qiuhong tan.Peizhi Yang Yingkai Liu Qianjin Wang College of Physics and Electronic Information Yunnan Normal UniversityKunming 650500China Yunnan Provincial Key Laboratory for Photoelectric Information Technology Yunnan Normal UniversityKunming 650500China Key Laboratory of Advanced Technique&Preparation for Renewable Energy materials Ministry of EducationYunnan Normal UniversityKunming 650500China

Two-dimensional(2D)transition metal dichalcogenides have been extensively studied due to their fascinating physical properties for constructing high-performance ***,their relatively low responsivities,current on/off ratios and response speeds have hindered their widespread ***,we fabricated a high-performance photodetector based on few-layer MoTe_(2) and CdS_(0.42)Se_(0.58) flake *** photodetector exhibited a high responsivity of 7221 A/W,a large current on/off ratio of 1.73×10^(4),a fast response speed of 90/120μs,external quantum efficiency(EQE)reaching up to 1.52×10^(6)%and detectivity(D*)reaching up to 1.67×10^(15) *** excellent performance of the heterojunction photodetector was analyzed by a photocurrent mapping test and first-principle ***,the visible light imaging function was successfully attained on the MoTe_(2)/CdS_(0.42)Se_(0.58) photodetectors,indicating that the device had practical imaging application *** findings provide a reference for the design of ultrahighperformance MoTe_(2)-based photodetectors.

关键词： photodetector MoTe_(2) heterojunction visible light imaging first-principles calculations

Operational requirements analysis method based on question answering of WEKG

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Journal of Systems Engineering and Electronics 2024年第2期35卷 386-395页

作者： ZHANG Zhiwei DOU Yajie XU Xiangqian ma Yufeng JIANG Jiang tan.Yuejin College of Systems Engineering National University of Defense TechnologyChangsha 410073China

The weapon and equipment operational requirement analysis(WEORA) is a necessary condition to win a future war,among which the acquisition of knowledge about weapons and equipment is a great challenge. The main challenge is that the existing weapons and equipment data fails to carry out structured knowledge representation, and knowledge navigation based on natural language cannot efficiently support the WEORA. To solve above problem, this research proposes a method based on question answering(QA) of weapons and equipment knowledge graph(WEKG) to construct and navigate the knowledge related to weapons and equipment in the WEORA. This method firstly constructs the WEKG, and builds a neutral network-based QA system over the WEKG by means of semantic parsing for knowledge navigation. Finally, the method is evaluated and a chatbot on the QA system is developed for the WEORA. Our proposed method has good performance in the accuracy and efficiency of searching target knowledge, and can well assist the WEORA.

关键词： operational requirement analysis weapons and equipment knowledge graph(WEKG) question answering(QA) neutral network

Grain size and surface micro-texture characteristics and their paleoenvironmental significance of Holocene sediment in southern margin of the Gurbantunggut Desert,China

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Journal of Arid Land 2024年第5期16卷 632-653页

作者： ma Yunqiang LI Zhizhong tan.Dianjia ZOU Xiaojun TAO Tonglian School of Geographical Sciences Fujian Normal UniversityFuzhou 350117China Key Laboratory for Humid Subtropical Eco-geographical Processes of the Ministry of Education Fujian Normal UniversityFuzhou 350117China Institute of Geography Fujian Normal UniversityFuzhou 350117China

The southern margin of the Gurbantunggut Desert,China,is characterized by alternating layers of aeolian and alluvial *** the characteristics of arenaceous sediment in this area is of significant importan.e for understan.ing the interactive processes of wind and water forces,as well as the provenance of ***,there are relatively few investigations on the characteristics of such sediment at *** this study,we researched three aeolian-alluvial interactive stratigraphic profiles and different types of surface sediment on the desert-oasis transitional zone of southern margin of the Gurbantunggut *** on the optically stimulated luminescence(OSL)dating of aeolian sand and analyses of quartz sand grain size and surface micro-texture,we explored the aeolian-alluvial environmental change at southern margin of the desert in Holocene,as well as the provenance of *** results indicated that the grain size characteristics of different types of sediment in the stratigraphic profiles were similar to those of modern dune sand,interdune sand,muddy desert surface soil,and riverbed *** frequency curves were unimodal or bimodal,and cumulative probability curves were two-segment or three-segment,mainly composed of suspension load and saltation *** quartz sand in the sediment at southern margin of the desert had undergone alternating transformation of various exogenic forces,with short transportation distan.e and time,and sedimentary environment was relatively *** Holocene,southern margin of the desert primarily featured braided river deposits,and during intermittent period of river activity,there were also aeolian deposits such as sand sheet deposits,stabilized dune deposits,and mobile dune *** provenance for Holocene alluvial deposits at southern margin of the desert remains relatively constan.,with the debris of the Tianshan Mountains being the primary *** sand is mainly near-source recharge,

关键词： aeolian-alluvial deposition grain size surface micro-texture sedimentary environment Holocene

A model for aircraft cabin evacuation considering passenger type

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Journal of Safety Science and Resilience 2024年第1期5卷 83-90页

作者： Yaping ma Jinfeng Yuan Lingling tan.Quanyi Liu Mengling Li Civil Aircraft Fire Science and Safety Engineering Key Laboratory of Sichuan Province Civil Aviation Flight University of ChinaGuanghan 618307China School of Safety Science and Emergency management Wuhan University of TechnologyWuhan 430070China

Pedestrian safety evacuation in aircraft cabins has been a challenging problem because of the aircraft’s unique characteristics,such as the diversity of passengers and the restricted evacuation *** is difficult to reproduce evacuation activities in aircraft cabin due to safety concerns and cost *** fill this gap,an improved cellular automaton model of crowd evacuation for aircraft cabin is established by incorporating the characteristics of cabin space structures and passenger *** are divided into healthy individual passengers and disabled-healthy group passengers,whose movement mechanisms are *** on the constructed model,simulation experiments are conducted using the configuration cabin layout of B737-800 as an *** results show that the evacuation time is prolonged with increased passenger density and the number of disabled ***,the overall evacuation time is insignificantly affected by whether disabled-healthy group passengers’seats are close to the aisle or window,and the evacuation efficiency is best when their seats are evenly distributed in the *** evacuation time is the shortest when all cabin doors are open,and pedestrians are evacuated the slowest when the central emergency doors are *** study pro-vides valuable insights into effective strategies for pedestrian evacuation and crowd emergency management of civil aircraft.

关键词： Aircraft cabin evacuation Passenger type Cellular automaton model Pedestrian distribution Evacuation efficiency

Mechanical behavior of rock under uniaxial tension:Insights from energy storage and dissipation

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第7期16卷 2466-2481页

作者： Guanshuang tan.Chunde ma Junjie Zhang Wenyuan Yang Guiyin Zhang Zihao Kang School of Resources and Safety Engineering Central South UniversityChangsha410083China

many rock engineering projects show that the growth of tensile cracks is often an importan. cause of engineering disasters,and the mechanical behavior of rocks is essentially the transmission,storage,dissipation and release of *** investigate the tensile behavior of rock from the perspective of energy,uniaxial tension tests(UTTs)and uniaxial compression tests(UCTs)were carried out on three typical rocks(granite,sandstone and marble).Different unloading points were set before the peak stress to separate elastic energy and dissipated *** input energy density ut,elastic energy density ue,and dissipated energy density ud at each unloading point were calculated by integrating stress-strain *** results show that there is a strong linear relationship between the three energy parameters and the square of the unloading stress in UCT,but this linear relationship is weaker in *** ue and ud increase linearly with the increase in ut in UCT and *** on the phenomenon that ue and ud increase linearly with ut,the applicability of W_(et)^(p) index in UTT was proved and the relative energy storage capacity and absolute energy distribution characteristics of three rocks in UCT and UTT were *** tensile behavior of marble and sandstone in UTT can be divided into two stages vaguely according to the energy distribution,but granite is not the *** addition,based on dissipated energy,the damage evolution of three types of rocks in UCT and UTT was *** study provides some new insights for understan.ing the tensile behavior of rock.

关键词： Uniaxial tension Energy density Mechanical behavior Energy storage coefficient Energy dissipation coefficient

A process insight into production of ethyl levulinate via a stepwise fractionation

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Journal of Bioresources and Bioproducts 2024年第2期9卷 233-242页

作者： Yan ma Hongxiao Wang Ziyang Wu Weihong tan.Guodong Feng Jianchun Jiang Institute of Chemical Industry of Forest Products Chinese Academy of ForestryNanjing 210042China Jiangsu Province Key Lab.of Biomass Energy and material Nanjing 210042China National Engineering Lab.for Biomass Chemical Utilization Nanjing 210042China Co-Innovation Center of Efficient Processing and Utilization of Forest Resources Nanjing Forestry UniversityNanjing 210037China

Ethyl levulinate(EL)is a key biomass-derived compounds due to its socio-economic benefits for the synthesis of commodity ***,we proposed an efficient one-step bamboo conversion to EL in ethanol,and a novel stepwise fractionation to purify EL and lignocellulose degradation products.A proton acid,due to its high catalytic efficiency,yielded 26.65%EL in 120 min at 200℃.The productions of ethyl glucoside and 5-ethoxymethylfurfural were analyzed in terms of by-products *** the best of our knowledge,there is no single report on catalyst for one step synthesis of EL directly from bamboo,as well as a stepwise fractionation to purify *** to similar physiochemical properties in each fraction,the platform molecules could broaden a new paradigm of bamboo biomass utilization for renewable energy and value-added *** addition,glucose,ethyl glucoside,corn starch,and microcrystalline cellulose were also investigated as substrates,so that the reaction intermediates of this one-pot procedure were identified and a possible reaction mechanism was proposed.

关键词： Ethyl levulinate Liquefaction Biomass Ethanol By-products

Analytical solution for the effective elastic properties of rocks with the tilted penny-shaped cracks in the transversely isotropic background

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Petroleum Science 2024年第1期21卷 221-243页

作者： Zheng-Qian ma Xing-Yao Yin Zhao-Yun Zong Yuan-Yuan tan.Ya-Ming Yang National Key Laboratory of Deep Oil and Gas China University of Petroleum(East China)Qingdao266580ShandongChina School of Geosciences China University of Petroleum(East China)Qingdao 266580ShandongChina Pilot National Laboratory for marine Science and Technology(Qingdao) Qingdao266200ShandongChina

Seismic prediction of cracks is of great significance in many disciplines,for which the rock physics model is ***,up to now,multitudinous analytical models focus primarily on the cracked rock with the isotropic background,while the explicit model for the cracked rock with the anisotropic background is rarely investigated in spite of such case being often encountered in the ***,we first studied dependences of the crack opening displacement tensors on the crack dip angle in the coordinate systems formed by symmetry planes of the crack and the background anisotropy,respectively,by forty groups of numerical *** on the conclusion from the experiments,the analytical solution was derived for the effective elastic properties of the rock with the inclined penny-shaped cracks in the transversely isotropic ***,we comprehensively analyzed,according to the developed model,effects of the crack dip angle,background anisotropy,filling fluid and crack density on the effective elastic properties of the cracked *** analysis results indicate that the dip angle and background anisotropy can significantly either enhance or weaken the anisotropy degrees of the P-and SH-wave velocities,whereas they have relatively small effects on the SV-wave velocity ***,the filling fluid can increase the stiffness coefficients related to the compressional modulus by reducing crack compliance parameters,while its effects on shear coefficients depend on the crack dip *** increasing crack density reduces velocities of the dry rock,and decreasing rates of the velocities are affected by the crack dip *** comparing with exact numerical results and experimental data,it was demonstrated that the proposed model can achieve high-precision estimations of stiffness ***,the assumption of the weakly anisotropic background results in the consistency between the proposed model and Hudson's published theory for the or

关键词： Effective elastic property Tilted crack Transverse isotropy Analytical solution Crack opening displacement

Aptamer-based Membrane Protein Analysis and Molecular Diagnostics

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Chemical Research in Chinese Universities 2024年第2期40卷 173-189页

作者： ZHAO Long HU Haolan ma Xiaoqian LYU Yifan YUAN Quan tan.Weihong Molecular Science and Biomedicine Laboratory(MBL) State Key Laboratory of Chemo/Biosensing and ChemometricsCollege of BiologyCollege of Chemistry and Chemical EngineeringAptamer Engineering Center of Hunan ProvinceHunan UniversityChangsha410082P.R.China The Cancer Hospital of the University of Chinese Academy of Sciences(Zhejiang Cancer Hospital) Hangzhou Institute of Medicine(HIM)Chinese Academy of SciencesHangzhou310022P.R.China Institute of Molecular Medicine(IMM) Renji HospitalSchool of MedicineCollege of Chemistry and Chemical EngineeringShanghai Jiao Tong UniversityShanghai200240P.R.China Furong Laboratory Changsha410082P.R.China

Membrane proteins are vital components of the cell membrane and play crucial roles in various cellular *** of membrane proteins is of paramount importan.e for studying molecular events inside cells and organisms and holds promising prospects for early disease diagnosis and treatment *** from obvious merits including high affinity,high specificity and ease of modification,aptamers have been regarded as ideal molecular recognition elements in membrane protein analysis and molecular diagnostics *** review summarised recent advances in membrane protein-specific aptamer screening,aptamer-based static and dynamic membrane protein analysis,and aptamer-based molecular diagnostic *** and challenges were also discussed.

关键词： Membrane protein Aptamer DNA nanotechnology Bioanalysis Molecular diagnostics