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Modulating the optical and electrical properties of MAPbBr_(3) single crystals via voltage regulation engineering and application in memristors

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Light(Science & Applications) 2020年第1期9卷 957-967页

作者： Jun Xing Chen Zhao Yuting Zou Wenchi Kong Zhi Yu Yuwei shan Qingfeng Dong Ding Zhou Weili Yu Chunlei Guo The Guo Photonics Laboratory State Key Laboratory of Applied OpticsChangchun Institute of OpticsFine Mechanics and PhysicsChinese Academy of Sciences130033 ChangchunChina University of Chinese Academy of Sciences 100049 BeijingChina State Key Laboratory of Supramolecular Structure and Materials Jilin University130012 ChangchunChina State Key Laboratory of Luminescence and Applications Changchun Institute of OpticsFine Mechanics and PhysicsChinese Academy of Sciences130033 ChangchunChina The Institute of Optics University of RochesterRochesterNY 14627USA

Defect density is one of the most significant characteristics of perovskite single crystals(PSCs)that determines their optical and electrical properties,but few strategies are available to tune this ***,we demonstrate that voltage regulation is an efficient method to tune defect density,as well as the optical and electrical properties of PSCs.A three-step carrier transport model of MAPbBr_(3) PSCs is proposed to explore the defect regulation mechanism and carrier transport dynamics via an applied *** and steady-state photoluminescence measurements subsequently show that the surface defect density,average carrier lifetime,and photoluminescence intensity can be efficiently tuned by the applied *** particular,when the regulation voltage is 20 V(electrical poling intensity is 0.167 Vμm^(−1)),the surface defect density of MAPbBr_(3) PSCs is reduced by 24.27%,the carrier lifetime is prolonged by 32.04%,and the PL intensity is increased by 112.96%.Furthermore,a voltage-regulated MAPbBr_(3) PSC memristor device shows an adjustable multiresistance,weak ion migration effect and greatly enhanced device *** regulation is a promising engineering technique for developing advanced perovskite optoelectronic devices.

关键词： optical electrical defect

Partitioning of rare earth elements and yttrium(REY)in five coal-fired power plants in Guizhou,Southwest China

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Journal of Rare Earths 2020年第11期38卷 1257-1264,I0005页

作者： Zhonggen Li Xinyu Li Leiming Zhang shan Li Ji Chen Xinbin Feng Dongbo Zhao Qingfeng Wang Zhixi Gao Bailian Xiong College of Resources and Environment Zunyi Normal UniversityZunyi 563006China State Key Laboratory of Environmental Geochemistry Institute of GeochemistryChinese Academy of SciencesGuiyang 550081China University of Chinese Academy of Sciences Beijing 100049China Air Quality Research Division Science and Technology BranchEnvironment and Climate Change CanadaTorontoM3H 5T4Canada College of Chemical Engineering Huaqiao UniversityXiamen 361021China

As indispensable strategic materials for high-tech industries,rare earth elements and yttrium(REY)have become particularly important in recent years,raising the demand of developing new approaches for reclamation of REY from REY-rich materials such as coal combustion products(CCPs).In this study,five coal-fired power plants(CFPPs)in Guizhou of southwest China were selected for investigating REY concentrations of solid samples,atmospheric emissions,and recovery *** concentrations of feed fuels are higher in this study(147.2-468.6 mg/kg)than what have been reported previously for coals in China and the *** atmospheric emissions are extremely low(38.70-180.11 mg REY/t coal).REY are enriched in bottom ash and fly ash,with average of 658±296 mg/kg and maximum of 1257 mg/kg from the five *** enrichment factors(REF)of REY in bottom ash and fly ash compared with the feed fuel are 0.86-1.02 and 0.91-1.04,*** concentrations in desulfurized gypsum are very low(6-17 mg/kg),and that is mostly inherited from *** REY(Nd,Eu,Tb,Dy,Y,and Er)in bottom/fly ash account for 34%-39%of the total REY and the outlook coefficients(Cout1)are in the range of *** study indicates a promising prospect to reclaim REY from REYrich CCPs(bottom and fly ash)in CFPPs in Guizhou,especially in the central-north Guizhou,although such practices require further technology advancement.

关键词： REY Bottom ash Fly ash Atmospheric emissions Reclamation Rare earths

Birefringent response of graphene oxide film structurized via femtosecond laser

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Nano Research 2022年第5期15卷 4490-4499页

作者： Tingting Zou Bo Zhao Wei Xin Feiyue Wang Hongbo Xie Yuhang Li Yuwei shan Kun Li Yanbing Sun Jianjun Yang The GPL Photonics Laboratory State Key Laboratory of Applied OpticsChangchun Institute of OpticsFine Mechanics and PhysicsChinese Academy of SciencesChangchun 130033China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China Key Laboratory of UV-Emitting Materials and Technology Ministry of EducationNortheast Normal UniversityChangchun 130024China Department of Electronic Information and Physics Changzhi UniversityChangzhi 046011China Changchun New Industries Optoelectronics Technology Co. LtdChangchun 130103China

In-plane birefringent materials present an effective modulation of the optical properties and more degrees of freedom for the signal detection in low dimension,and thus remain a hot topic in realizing the integrated,miniature,and flexible devices for multiple ***,the artificial in-plane birefringence properties have been successfully achieved on a graphene oxide film by a novel femtosecond laser lithography method,which provides a high-speed,large-area,and regular subwavelength gratings(~380 nm)fabrication and *** obtained sample manifests an evident optical birefringence(~0.18)and anisotropic photoresponse(~1.21)in the visible range,both of which can be significantly modulated by either the structural morphology or the degree of oxide *** on the analysis of effective-medium theory and measurements of angle-resolved polarized Raman spectroscopy,the artificial in-plane birefringence is originated from various optical responses of the periodic subwavelength structures for the incident light with different polarization *** technique shows great advantages for the fabrication of integrated in-plane polarization-dependent devices,which is expected to solve the problems in this field,such as the deficient selection of materials,complex design of micro/nanostructure,and inflexible processing technology.

关键词： femtosecond laser lithography reduced graphene oxide subwavelength structures in-plane birefringence anisotropic photoresponse

Mechanisms of chromatin-based epigenetic inheritance

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Science China(Life Sciences) 2022年第11期65卷 2162-2190页

作者： Wenlong Du Guojun Shi Chun-Min shan Zhiming Li Bing Zhu Songtao Jia Qing Li Zhiguo Zhang National Laboratory of Biomacromolecules CAS Center for Excellence in BiomacromoleculesInstitute of BiophysicsChinese Academy of SciencesBeijing10010lChina State Key Laboratory of Protein and Plant Gene Research School of Life Sciences and Peking-Tsinghua Center for Life SciencesPeking UniversityBeijing10087lChina State Key Laboratory of Plant Genomics Institute of MicrobiologyChinese Academy of SciencesBejing 100101China Institutes of Cancer Genetics Herbert Irving Comprehensive Cancer CenterColumbia University Medical CenterNew YorkNY10032USA College of Life Sciences University of Chinese Academy of SciencesBejing 100049China Department of Biological Sciences Columbia Universiy.New YorkNY 10027USA

Multi-cellular organisms such as humans contain hundreds of cell types that share the same genetic information(DNA sequences),and yet have different cellular traits and *** how genetic information is passed through generations has been extensively characterized,it remains largely obscure how epigenetic information encoded by chromatin regulates the passage of certain traits,gene expression states and cell identity during mitotic cell divisions,and even through *** this review,we will summarize the recent advances on molecular mechanisms of epigenetic inheritance,discuss the potential impacts of epigenetic inheritance during normal development and in some disease conditions,and outline future research directions for this challenging,but exciting field.

关键词： epigenetic inheritance histone modification DNA methylation histone deposition DNA replication

Physiological and histological responses of Phascolosoma esculenta (Sipuncula: Phascolosomatidea) to acute heat stress

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Journal of Oceanology and Limnology 2022年第2期40卷 643-655页

作者： Xinming GAO Haiyan YANG Daojun TANG Chen DU shan JIN Congcong HOU Chundan ZHANG Junquan ZHU Jianping WANG Key Laboratory of Applied Marine Biotechnology by the Ministry of Education School of Marine SciencesNingbo UniversityNingbo 315211China Ningbo Academy of Oceanology and Fisheries Ningbo 315012China

Temperature is an important factor affecting the growth,development,and survival of *** effects of temperature stress on aquatic organisms have received increasing attention,as these organisms are mostly poikilotherms and their body temperature are directly corresponding changes with ambient temperature,resulting in they are easily exposed in temperature ***,little is known about the effects of high temperature on *** this study,we investigated the effects of acute heat stress on malondialdehyde(MDA)concentration,the activities of antioxidant(superoxide dismutase and glutathione peroxidase)and immunity-related(acidic and alkaline phosphatase)enzymes,heat shock protein 70(hsp70)and hsp90 gene expression,and the histological structure of the sipunculid Phascolosoma *** the coelom fl uid,the MDA concentration and all detected antioxidant enzyme activities increased during high temperature stress;signifi cant increases were also observed here and in the intestine in the hsp70 and hsp90 mRNA expression *** results indicated that acute heat stress caused oxidative stress;antioxidants and heat shock proteins probably act to protect *** against oxidative damage,constituting part of its physiological mechanism for adaptation to high *** addition,the increased activity of the acidic and alkaline phosphatases indicated eff ects on its nonspecifi c immune ***,damaged tissue structures were observed in the body wall,retractor muscle,intestine,and nephridium after 96 h of 40-℃ *** damaged cells of these tissues showed obvious condensed chromatin around the nuclear *** histological damage suggests that heat stress could affect movement,food absorption,digestion,and excretion in *** results elucidate the effects of temperature stress on *** and its physiological response mechanisms and provide practical indicators for assessing heat stress status and determi

关键词： heat stress oxidation stress enzyme activity heat shock proteins nonspecific immunity histological damage

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39例面部基底細胞癌手術切緣分析

镜湖医学 2020年第1期20卷 43-44,42页

作者：黃海山曾婉君古杰鳴澳門鏡湖醫院皮膚科中國澳門鏡湖醫院病理科中國

目的探索面部基底細胞癌手術切緣距腫瘤邊界5mm的可靠性。方法39例面部基底細胞癌患者,以肉眼及三倍放大鏡觀察邊界,在腫瘤邊界向外擴大5mm行手術切除,標本切緣標記3、6、9、12時鐘方向後進行病理檢查,了解腫瘤殘留狀況。結果39例病理... 详细信息

目的探索面部基底細胞癌手術切緣距腫瘤邊界5mm的可靠性。方法39例面部基底細胞癌患者,以肉眼及三倍放大鏡觀察邊界,在腫瘤邊界向外擴大5mm行手術切除,標本切緣標記3、6、9、12時鐘方向後進行病理檢查,了解腫瘤殘留狀況。結果39例病理檢查切緣均未見腫瘤。結論以肉眼及三倍放大鏡確定腫瘤邊界後向外擴展5mm能乾淨切除腫瘤。

关键词：皮膚基底細胞癌手術治療手術切緣

Upregulation of 14-3-3γ is induced by a synergistic effect of multiple factors during ischemia in astrocytes

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Upregulation of 14-3-3γ is induced by a synergistic effect ...

基于溶液法的规则排列连续晶畴的金属诱导多晶硅薄膜及薄膜晶体管(英文)

中国神经科学学会第十届全国学术会议

作者： Ymg PANG Yan DONG Hua-Dong LIU Ann Yuen Kwan wong Greg VATCHER Xiao-Qian CHEN Jian-Guo CHEN Albert Cheung hoi YU Neuroscience Research Institute Department of Neurobiology Key Laboratory for Neuroscience (Peking University) Ministry of Education Key Laboratory for Neuroscience (Peking University) Ministry of Public Health Department of Neurobiology School of Basic Medical Sciences Peking University Health Science Center Department of Pathophysiology the Key Laboratory of Neurological Diseases the Ministry of Education and Department of Pharmacology Tongji Medical College Huazhong University of Science and Technology Department of Cell Biology and Genetics College of Life Sciences Peking University Key Laboratory for Cell Proliferation and Differentiation Ministry of Education State Key Laboratory for Bio-membrane and Membrane Bio-engineering Laboratory ofTranslattonal Medicine Institute of Systems Biomedicine Peking University

14-3-3γ is a multifunctional acidic protein that is induced by ischemia in neural cells,including astrocytes,and has a neuroprotective *** ischemia,a lack of oxygen（hypoxia） and glucose,and an accumulation of toxins,*** order to elucidate which ischemia components caused the damage to astrocytes and the induction of the protective protein 14-3-3γ,we examined the effects of hypoxia,glucose deprivation,and the accumulation of toxins,separately,and compared the degree of damage to ischemia *** caused a rapid upregulation of 14-3-3γthat occurred within 1 to 4 *** alone elevated 14-3-3γ expression,while glucose deprivation did not cause a detectable change in the 14-3-3γ mRNA and protein *** changes of toxic metabolites barely affected14-3-3γ gene and protein expression in the time course *** addition,comparing the activation of the ERK1/2,Akt,P38 and JNK signaling pathways under ischemia and hypoxia in astrocytes revealed mat ischemia activated all four pathways,while hypoxia had little effect on any of *** also observed how glutamate（Glu） and arachidonic acid（AA）,the main toxic substances released by neural cells during ischemia injury,affected the expression of the14-3-3 protein *** all members of the 14-3-3 family,β and γ were up-regulated rapidly after 3 hr of treatment with G1u or AA,while η and ε increased until 6 hr and ζ increased after *** results demonstrated that the three components of ischemia played diverse roles in the regulation of 14-3-3Y) that different isoforms of the 14-3-3family showed disparate responses to Glu and AA treatments,and that the JNK/c-Jun/AP-1 signaling pathway was involved in 14-3-3γ up-regulation.

关键词： 14-3-3γ hypoxia ischemia glutamate arachidonic acid

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液晶与显示 2010年第3期25卷 333-338页

作者：赵淑云孟志国王文郭海成香港科技大学电子及计算机工程系南开大学光电子所天津300071

介绍了一种新的金属诱导多晶硅技术。该技术的核心是预设规则化晶核定位孔和镍源补充孔与溶液浸蘸技术的结合。以定位孔为晶化的起始点,晶化过程中消耗的镍可通过分布在周边的镍源补充孔中的镍给予补充。这样可以大大降低晶核定位孔中... 详细信息

介绍了一种新的金属诱导多晶硅技术。该技术的核心是预设规则化晶核定位孔和镍源补充孔与溶液浸蘸技术的结合。以定位孔为晶化的起始点,晶化过程中消耗的镍可通过分布在周边的镍源补充孔中的镍给予补充。这样可以大大降低晶核定位孔中的初始镍量,使整个多晶硅薄膜中不存在明显的高镍含量区。即包括晶核定位孔、镍源补充孔在内的整个多晶硅薄膜区域内,能形成连续晶畴的多晶硅薄膜,都可作为高质量TFT的有源层。根据晶核定位孔分布形式的不同,可以设计成规则、重复的分布形式,获得正六边形的蜂巢晶体薄膜和准平行晶带晶体薄膜。这些规则形成的晶畴形状与尺寸相同,可准确地控制晶化的过程,具有晶化时间的高可控性和工艺过程的高稳定性,故而适合于工业化生产的要求。利用些技术,当温度为590 ℃时,可将晶化时间缩短至2 h之内。用这种多晶硅薄膜为有源层,所得多晶硅TFT的场效应迁移率典型值为～55 cm2/V.s ,亚阈值斜摆幅为0 .6 V/dec ,开关电流比为～1×107,开启电压为-3 V。

关键词：金属诱导晶化规则排列连续晶畴薄膜晶体管低温多晶硅

Pancreatic melatonin enhances anti-tumor immunity in pancreatic adenocarcinoma through regulating tumor-associated neutrophils infiltration and NETosis

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Acta Pharmaceutica Sinica B 2023年第4期13卷 1554-1567页

作者： Yau-tuen Chan Hor-yue Tan Yuanjun Lu Cheng Zhang Chien-shan Cheng Junyu Wu Ning Wang Yibin Feng School of Chinese Medicine the University of Hong KongHong KongChina Centre for Chinese Herbal Medicine Drug Development School of Chinese MedicineHong Kong Baptist UniversityHong KongChina Department of Traditional Chinese Medicine Shanghai Jiaotong UniversitySchool of Medicine Affiliated Ruijin HospitalShanghai 200025China

Tumor microenvironment contributes to poor prognosis of pancreatic adenocarcinoma(PAAD)*** regulation could improve *** is an endogenous hormone that delivers multiple *** we showed that pancreatic melatonin level is associated with patients'*** PAAD mice models,melatonin supplementation suppressed tumor growth,while blockade of melatonin pathway exacerbated tumor *** anti-tumor effect was independent of cytotoxicity but associated with tumor-associated neutrophils(TANs),and TANs depletion reversed effects of *** induced TANs infiltration and activation,therefore induced cell apoptosis of PAAD *** arrays revealed that melatonin had minimal impact on neutrophils but induced secretion of Cxcl2 from tumor *** of Cxcl2 in tumor cells abolished neutrophil migration and ***-induced neutrophils presented an N1-like anti-tumor phenotype,with increased neutrophil extracellular traps(NETs)causing tumor cell apoptosis through cell-to-cell *** analysis revealed that this reactive oxygen species(ROS)-mediated inhibition was fueled by fatty acid oxidation(FAO)in neutrophils,while FAO inhibitor abolished the anti-tumor *** of PAAD patient specimens revealed that CXCL2 expression was associated with neutrophil ***2,or TANs,combined with NET marker,can better predict patients'***,we discovered an anti-tumor mechanism of melatonin through recruiting N1-neutrophils and beneficial NET formation.

关键词： Pancreatic adenocarcinoma Melatonin Anti-tumor immunity Tumor-associated neutrophils Tumor microenvironment CXCL2 Neutrophil extracellular traps NETosis