检索结果-南通市图书馆

Food science and Human Wellness 2024年第3期13卷 1617-1627页

作者： Weiyun Zhang Chi-Tang ho Wenlian Wei Jie Xiao Muwen Lu Guangdong Provincial Key Laboratory of Nutraceuticals and Functional Foods College of Food ScienceSouth China Agricultural UniversityGuangzhou 510642China Department of Food science Rutgers UniversityNew Brunswick 08901USA

The interplay between the host circadian clock and microbiota has significant influences on host metabolism processes,and circadian desynchrony triggered by high-fat diet(HFD)is closely related to metabolic *** this study,the modulatory effects of piperine(PIP)on lipid metabolism homeostasis,gut microbiota community and circadian rhythm of hepatic clock gene expressions in obese rats were *** sprague-Dawley(sD)rats were fed with normal diet(ND),HFD and HFD supplemented with PIP,*** 9 weeks,rats were sacrificed with tissue and fecal samples collected for circadian *** showed that chronic PIP administration ameliorated the obesity-induced alterations in lipid metabolism and dysregulation of hepatic clock gene expressions in obese *** gut microbial communities studied through 16s rRNA sequencing showed that PIP ameliorated the imbalanced nicrobiota and recovered the circadian rhythm of Lactobacillaceae,Desulfovibrionaceae,Paraprevotellaceae,and *** fecal metabolic profiles indicated that 3-dehydroshikimate,cytidine and lithocholyltaurine were altered,which were involved in the amino acid and fatty acid metabolism *** findings could provide theoretical basis for PIP to work as functional food to alleviate the lipid metabolism disorder,circadian rhythm misalignment,and gut microbiota dysbiosis with wide applications in the food and pharmaceutic industries.

关键词： Piperine Circadian clock Obesity Gut microbiota

Rescattering of stimulated Raman side scattering in nonuniform plasmas

在线全文

学校读者我要写书评

暂无评论

Matter and Radiation at Extremes 2024年第5期9卷 68-76页

作者： s.Tan Q.Wang y.Chen W.B.yao C.Z.Xiao J.F.Myatt school of Physics and Electronics Hunan UniversityChangsha 410082China Institute of Applied Physics and Computational Mathematics Beijing 100094China school of Electrical and Information Engineering Anhui University of Science and TechnologyHuainanAnhui 232001China Department of Electrical and Computer Engineering University of Alberta9211116 St.NWEdmontonAlberta T6G 1H9Canada

Rescattering of stimulated Raman side scattering(sRss)is observed for the first time via two-dimensional(2D)particle-in-cell(PIC)*** construct a theoretical model for the rescattering process,which can predict the region of occurrence of mth-order sRss and estimate its *** rescattering process is identified by the 2D PIC simulations under typical conditions of a direct-drive inertial confinement fusion *** electrons produced by second-order sRss propagate nearly perpendicular to the density gradient and gain nearly the same energy as in first-order sRss,but there is no cascade acceleration to produce superhot *** studies for a wide range of ignition conditions show that sRss and associated rescatterings are robust and important processes in inertial confinement fusion.

关键词： nonuniform acceleration scattering

Effect of radiative loss mechanisms on FIR thermometric parameters of Nd^(3+)-doped lithium tellurite glasses

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Rare Earths 2024年第7期42卷 1250-1257,I0002页

作者： C.y.Morassuti A.P.L silva L.A.O.Nunes s.M.Lima L.H.C.Andrade Optical and Photothermal spectroscopy Group(GEOF) Center for Studies in Natural Resources(CERNA)State University of Mato Grosso do Sul(UEMS)C.P.351DouradosMSBrazil Renato Archer Information Technology Center Dom Pedro I Highway(SP-65)Km 1436-Chácaras Campos dos AmaraisCampinasSPBrazil Institute of Physics of são Carlos University of São PauloSão CarlosSPBrazil

Nd^(3+)-doped tellurite glasses are promising materials for thermometers based on the fluorescence intensity ratio(FIR)***,at high Nd^(3+)concentrations,energy transfer(ET)processes such as optical reabsorption and cross-relaxation can affect the Nd^(3+)emission,which has been little explored in the ***,the present work investigated the use of Nd^(3+)-doped tellurite glass(samples doped with Nd^(3+)at 0.2 mol%,0.5 mol%,2.0 mol%,and 4.0 mol%)in fluorescence thermometers,in the temperature range from 299 to 371 *** results indicate a strong dependence of the FIR parameters on the Nd^(3+)concentration,due to changes in the emission band profiles caused by optical reabsorption of the Nd^(3+)emissions and cross-relaxation processes.A decrease of the relative sensitivity of the ratio^(4)F_(5/2)→^(4)I_(9/2)/^(4)F_(3/2)→^(4)I_(9/2)is observed for samples doped with higher amounts of Nd^(3+).The maximum relative sensitivity at 299 K is 3.00%/K,which is the highest value among the reported Nd^(3+)ions.

关键词： Nd^(3+)-doped tellurite glass Fluorescence intensity ratio Optical thermometry Judd-Ofelt Rare earths

Electron kinetic effects in back-stimulated Raman scattering bursts driven by broadband laser pulses

在线全文

学校读者我要写书评

暂无评论

Matter and Radiation at Extremes 2024年第4期9卷 54-67页

作者： Q.K.Liu L.Deng Q.Wang X.Zhang F.Q.Meng y.P.Wang y.Q.Gao H.B.Cai s.P.Zhu Graduate school China Academy of Engineering PhysicsBeijing 100088China Institute of Applied Physics and Computational Mathematics Beijing 100094China school of Nuclear science and Technology University of Science and Technology of ChinaHefei 230026China shanghai Institute of Laser Plasma Shanghai 201800China HEDPs Center for Applied Physics and TechnologyPeking UniversityBeijing 100871China school of Physics Zhejiang UniversityHangzhou 310027China

We examine electron kinetic effects in broadband-laser-driven back-stimulated Raman scattering(BsRs)bursts using particle-in-cell *** bursts occur during the nonlinear stage,causing reflectivity spikes and generating large numbers of hot ***-duration simulations are performed to observe burst events,and a simplified model is developed to eliminate the interference of the broadband laser’s random intensity *** the simplified model,we isolate and characterize the spectrum of electron plasma *** spectrum changes from a sideband structure to a turbulence-like structure during the burst.A significant asymmetry in the spectrum is *** asymmetry is amplified and transferred to electron phase space by high-intensity broadband laser pulses,leading to violent vortex-merging and generation of hot *** proportion of hot electrons increases from 6.76%to 14.7%during a single violent burst *** demonstrate that kinetic effects profoundly influence the BsRs evolution driven by broadband lasers.

关键词： scattering kinetic simplified

New insights into ATR inhibition in muscle invasive bladder cancer:The role of apolipoprotein B mRNA editing catalytic subunit 3B

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oncology Research 2024年第6期32卷 1021-1030页

作者： HyUNho KIM UIJU Cho sOOK HEE hoNG HyUNG sOON PARK IN-ho KIM ho JUNG AN ByOUNG yONG sHIM JIN HyOUNG KANG Division of Medical Oncology Department of Internal MedicineSt.Vincent’s HospitalCollege of MedicineThe Catholic University of KoreaSuwonKorea Department of Pathology St.Vincent’s HospitalCollege of MedicineThe Catholic University of KoreaSuwonKorea Division of Medical Oncology Department of Internal MedicineSeoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoulKorea

Background:Apolipoprotein B mRNA editing catalytic polypeptide(APOBEC),an endogenous mutator,induces DNA damage and activates the ataxia telangiectasia and Rad3-related(ATR)-checkpoint kinase 1(Chk1)*** cisplatin-based therapy is the mainstay for muscle-invasive bladder cancer(MIBC),it has a poor survival ***,this study aimed to evaluate the efficacy of an ATR inhibitor combined with cisplatin in the treatment of APOBEC catalytic subunit 3B(APOBEC3B)expressing ***:Immunohistochemical staining was performed to analyze an association between APOBEC3B and ATR in patients with *** APOBEC3B expression in MIBC cell lines was assessed using real-time polymerase chain reaction and western blot *** blot analysis was performed to confirm differences in phosphorylated Chk1(pChk1)expression according to the APOBEC3B *** viability and apoptosis analyses were performed to examine the anti-tumor activity of ATR inhibitors combined with ***:There was a significant association between APOBEC3B and ATR expression in the tumor tissues obtained from patients with *** with higher APOBEC3B expression showed higher pChk1 expression than cells expressing low APOBEC3B *** treatment of ATR inhibitor and cisplatin inhibited cell growth in MIBC cells with a higher APOBEC3B *** to cisplatin single treatment,combination treatment induced more apoptotic cell death in the cells with higher APOBEC3B ***:Our study shows that APOBEC3B’s higher expression status can enhance the sensitivity of MIBC to cisplatin upon ATR *** result provides new insight into appropriate patient selection for the effective application of ATR inhibitors in MIBC.

关键词： Apolipoprotein B mRNA editing catalytic polypeptide(APOBEC) Ataxia telangiectasia and Rad3-related(ATR) Bladder cancer DNA damage response DNA replication stress

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

On B(5,20)2-Groups

Algebra Colloquium 2024年第3期31卷 429-440页

作者： E.A.Alhassan y.L.Tan y.Li school of Mathematical sciences Jiangsu UniversityZhenjiangJiangsu 212013China Department of Mathematics Brock UniversitySt.CatharinesOntario L2S 3A1Canada

A finite group G is said to be a B(n,k)group if for any n-element subset[a_(1),…,a_(n)]of G,|{a_(i)a_(j)|1≤i,j≤n}|≤*** is of interest to characterize the structure of B(n,k)groups for n(n+1)/2≤k≤n^(2)-*** B(5,k)groups for 15≤k≤19 have been investigated by several *** this paper,we give a complete characterization of B(5,20)2-groups by showing there are five classes of such groups which are nontrivial and nonabelian.

关键词： B(n,k)groups small squaring property central extension GAP

An Efficient Long short-TermMemory and Gated Recurrent Unit Based smart Vessel Trajectory Prediction Using Automatic Identification system Data

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials and Continua 2024年第1期81卷 1789-1808页

作者： Zaman U. Khan J. Lee E. Hussain s. Balobaid A.s. Aburasain R.y. Kim K. Department of Computer Engineering Chungnam National University Daejeon 34134 South Korea Department of Environmental IT Engineering Chungnam National University Daejeon 34134 South Korea Autonomous ship Research Center Samsung Heavy Industries Daejeon 34051 South Korea ICAROs Center (PRIsMA Lab) University of Naples Federico II Naples 80131 Italy Department of Computer science College of Computer Science and Information Technology Jazan University Jazan 45142 Saudi Arabia

Maritime transportation, a cornerstone of global trade, faces increasing safety challenges due to growing sea traffic volumes. This study proposes a novel approach to vessel trajectory prediction utilizing Automatic Identification system (AIs) data and advanced deep learning models, including Long short-Term Memory (LsTM), Gated Recurrent Unit (GRU), Bidirectional LsTM (DBLsTM), simple Recurrent Neural Network (simpleRNN), and Kalman Filtering. The research implemented rigorous AIs data preprocessing, encompassing record deduplication, noise elimination, stationary simplification, and removal of insignificant trajectories. Models were trained using key navigational parameters: latitude, longitude, speed, and heading. spatiotemporal aware processing through trajectory segmentation and topological data analysis (TDA)was employed to capture dynamic *** using a three-month AIs dataset demonstrated significant improvements in prediction accuracy. The GRU model exhibited superior performance, achieving training losses of 0.0020 (Mean squared Error, MsE) and 0.0334 (Mean Absolute Error, MAE), with validation losses of 0.0708 (MsE) and 0.1720 (MAE). The LsTM model showed comparable efficacy, with training losses of 0.0011 (MsE) and 0.0258 (MAE), and validation losses of 0.2290 (MsE) and 0.2652 (MAE). Both models demonstrated reductions in training and validation losses, measured by MAE, MsE, Average Displacement Error (ADE), and Final Displacement Error (FDE). This research underscores the potential of advanced deep learning models in enhancing maritime safety through more accurate trajectory predictions, contributing significantly to the development of robust, intelligent navigation systems for the maritime industry. © 2024 The Authors. Published by Tech science Press.

关键词： AIs data deep learning GRU LsTM smart vessel Trajectory prediction

A perspective on age-related changes in cell environment and risk of neurodegenerative diseases

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第4期19卷 719-720页

作者： Alice y.Liu Department of Cell Biology and Neuroscience Rutgers State University of New JerseyPiscatawayNJUSA

“Age-related neurodegenerative disease”underscores human age as the primary risk factor for disease development:Alzheimer’s,Parkinson’s,and Huntington’s disease(HD)as *** for the age-dependent delay in disease manifestation,in particular for autosomal dominant forms of the disease,and the underlying cause(s)of specific neuron dysfunction and death to manifest as memory loss,anxiety,depression,and agitation in disease subjects remain *** are interested in understanding age-related changes in cell environment that can modulate the structure,function,aggregation.

关键词： Huntington Alzheimer death

A Collocation Technique via Pell-Lucas Polynomials to solve Fractional Differential EquationModel for HIV/AIDs with Treatment Compartment

在线全文

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & sciences 2024年第10期141卷 281-310页

作者： Gamze yıldırım suayip yüzbası Department of Mathematics Faculty of ScienceAkdeniz UniversityAntalya07058Turkey Department of Mathematics Faculty of Basic ScienceGebze Technical UniversityKocaeli41400Turkey Department of Mathematics Faculty of ScienceBartın UniversityBartın74100Turkey

In this study,a numerical method based on the Pell-Lucas polynomials(PLPs)is developed to solve the fractional order HIV/AIDs epidemic model with a treatment *** HIV/AIDs mathematical model with a treatment compartment is divided into five classes,namely,susceptible patients(s),HIV-positive individuals(I),individuals with full-blown AIDs but not receiving ARV treatment(A),individuals being treated(T),and individuals who have changed their sexual habits sufficiently(R).According to the method,by utilizing the PLPs and the collocation points,we convert the fractional order HIV/AIDs epidemic model with a treatment compartment into a nonlinear system of the algebraic ***,the error analysis is presented for the Pell-Lucas approximation *** aim of this study is to observe the behavior of five populations after 200 days when drug treatment is applied to HIV-infectious and full-blown AIDs *** demonstrate the usefulness of this method,the applications are made on the numerical example with the help of *** addition,four cases of the fractional order derivative(p=1,p=0.95,p=0.9,p=0.85)are examined in the range[0,200].Owing to applications,we figured out that the outcomes have quite decent ***,we understand that the errors decrease when the value of N *** figures in this study are created in *** outcomes indicate that the presented method is reasonably sufficient and correct.

关键词： Collocation method fractional differential equations HIV/AIDs epidemic model Pell-Lucas polynomials

supposition of graphene stacks to estimate the contact resistance and conductivity of nanocomposites

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2024年第4期45卷 663-676页

作者： y.ZARE M.T.MUNIR G.J.WENG K.y.RHEE Biomaterials and Tissue Engineering Research Group Department of Interdisciplinary TechnologiesBreast Cancer Research CenterMotamed Cancer InstituteTehran ***Iran College of Engineering and Technology American University of the Middle EastEgaila 54200Kuwait Department of Mechanical and Aerospace Engineering Rutgers UniversityNew BrunswickNJ 08903U.S.A. Department of Mechanical Engineering(BK21 Four) College of EngineeringKyung Hee UniversityYongin 446701Republic of Korea

In this study,the effects of stacked nanosheets and the surrounding interphase zone on the resistance of the contact region between nanosheets and the tunneling conductivity of samples are evaluated with developed equations superior to those previous.y.*** contact resistance and nanocomposite conductivity are modeled by several influencing factors,including stack properties,interphase depth,tunneling size,and contact *** developed model's accuracy is verified through numerous experimental *** further validate the models and establish correlations between parameters,the effects of all the variables on contact resistance and nanocomposite conductivity are ***,the contact resistance is primarily dependent on the polymer tunnel resistivity,contact area,and tunneling *** dimensions of the graphene nanosheets significantly influence the conductivity,which ranges from 0 s/m to90 s/*** increased number of nanosheets in stacks and a larger gap between them enhance the nanocomposite's ***,the thicker interphase and smaller tunneling size can lead to higher sample conductivity due to their optimistic effects on the percolation threshold and network efficacy.

关键词： graphene polymer composite stacked nanosheet tunneling conductivity contact resistance interphase