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Apolipoprotein A-I binding protein-mediated neuroprotection in glaucomatous neuroinflammation and neurodegeneration

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Neural Regeneration Research 2025年第5期20卷 1414-1415页

作者： Sinwoo hwang Seunghwan Choi Soo-ho Choi Keun-Young Kim Yury I.Miller Won-Kyu Ju Hamilton Glaucoma Center and Shiley Eye Institute The Viterbi Family Department of OphthalmologyUniversity of California San DiegoLa JollaCAUSA Department of Medicine University of California San DiegoLa JollaCAUSA National Center for Microscopy and Imaging Research Department of NeurosciencesUniversity of California San DiegoLa JollaCAUSA

Glaucoma is a multifactorial eye disorder that can cause vision loss and irreversible blindness,affecting individ uals aged 40 to 80 yea rs *** to the aging population,it is expected that the number of people affected by glaucoma will surpass 111 million by 2040 as the disease becomes more *** primarily contributes to optic nerve axon loss and the progressive degeneration of retinal ganglion cells (RGCs),subsequently leading to vision impairment.

关键词： irreversible pass primarily

Immediate muscle strengthening by an end-effector type gait robot with reduced real-time use of leg muscles: A case series and review of literature

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World Journal of Clinical Cases 2019年第19期7卷 2976-2985页

作者： Chang ho hwang Department of Physical Medicine and Rehabilitation Ulsan University Hospital University of Ulsan College of Medicine Department of Biomedical Engineering School of Electrical EngineeringUniversity of Ulsan

BACKGROUND De-afferentation or non-weight bearing induces rapid cortical and spinalα-motor neuron *** supposed that an end-effector type gait robot(EEGR)could provide patients with a training condition that was specific enough to activate rapid cortical/spinal neuroplasticity,leading to immediate muscle *** electromyographic and biomechanical comparisons were *** To compare the electromyographic activities of the thigh and shank muscles and isometric peak torque(PT)before and after walking training on a floor or in the end-effector gait *** Twelve outpatients without ambulatory dysfunction were *** of two interventions(5-min training on a floor at a comfortable pace or training in an EEGR with non-weight bearing on their feet and 100%guidance force at 2.1 km/h)were randomly *** PT,maximal ratio of torque development,amplitude of compound motor action potential(CMAP),and area under the curve(AUC)were evaluated before and 10 min after both *** The degree of PT improvement of the dominant knee flexors was larger in the EEGR than on the floor(9.6±22.4 Nm/BW,Phose who trained on the floor(4.5±28.1 Nm/BW,Phowever,all electromyographic activities of the thigh and shank muscles(peak CMAP,mean and peak AUC)were significantly lower for the use of the EEGR than walking on the *** Immediate strengthening of the knee flexors and extensors was induced after the 5-min EEGR training,despite reduced muscular use.

关键词： Robotics Rehabilitation Muscles Neuronal plasticity Gait Knee

Is endoscopic ultrasonography still the modality of choice in preoperative staging of gastric cancer?

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World Journal of Gastroenterology 2014年第38期20卷 13775-13782页

作者： Sung Wook hwang Dong ho Lee Department of Internal Medicine and Liver Research Institute Seoul National University College of Medicine Department of Internal Medicine Seoul National University Bundang HospitalSeongnam

The treatment option for gastric cancer is usually based on preoperative staging by imaging modalities. Endoscopic ultrasonography (EUS) and computed tomography (CT) have been used as the diagnostic modality of choice in preoperative staging of gastric cancer. Magnetic resonance imaging (MRI) has been employed in several studies, and (18F) 2-Fluoro-2-deoxyglucose (FDG) positron emission tomography (PET) has emerged as a new promising imaging modality. The purpose of this article is to provide summarized information on preoperative staging using EUS, multi-detector row CT (MDCT), MRI and PET for gastric cancer. In T staging, both EUS and MDCT show high accuracy. MRI seemed to have better performance, but the number of MRI studies is limited. FDG-PET is not able to properly evaluate the depth of invasion. In N staging, the diagnostic accuracy of EUS, MDCT and MRI is not sufficient. In preoperative M staging, MDCT and FDG-PET showed similar diagnostic accuracies. FDG-PET/CT fusion could be expected to show better performance in the future. Physicians should keep in mind that each diagnostic modality has advantages and limitations and choose an appropriate diagnostic strategy tailored for each patient.

关键词： Gastric cancer Endoscopic ultrasonography Computed tomography Magnetic resonance imaging Positron emission tomography

A comparative study of interface reconstruction algorithms in molten metal flow

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China Foundry 2013年第1期10卷 50-56页

作者： Young-Sim Choi Jun-ho hong ho-Young hwang e-Design Center Korea Institute of Industrial TechnologyIncheon 406-840Korea

In the present research,two numerical schemes for improving the accuracy of the solution in the flow simulation of molten metal were *** method is the Piecewise Linear Interface Calculation(PLIC) method and the other is the Donor-Acceptor(D-A) *** verify the module of the interface reconstruction algorithms,simple problems were *** these validations,the accuracy and efficiency of these two methods were compared by simulating various real *** the numerical simulation of free surface flow,it is possible for the PLIC method to track very accurately the interface between *** PLIC method,however,has the weak point in that a lot of computational time is required,though it shows the more accurate interface *** Donor-Acceptor method has enough effectiveness in the macro-observation of a mold filling sequence though it shows inferior ***,for the problems that need the accurate solution,PLIC is more appropriate than *** accuracy may cause less efficiency in numerical *** method between D-A method and PLIC method should be chosen depends on the product.

关键词： interface reconstruction DA PLIC molten metal flow accuracy volume of fluid method

The occurrence of arthropods in processed rice products in Malaysia

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Asian Pacific Journal of Tropical Medicine 2010年第7期3卷 552-554页

作者： Mariana A Heah sk Wong AL ho TM Acarology Unit Infectious Diseases Research CentreInstitute for Medical Research.Jalan Pahang50588 Kuala LumpurMalaysia

Objective:To determine distribution of arthropods in processed rice products such as rice flour and rice cereal-based infant ***:Random samples of rice flour and rice cereal-based infant food purchased from commercial outlets were examined for the presence of arthropods using a modified Berlese Tullgren Funnel *** were mounted prior to identification and weevils were directly ***:For non-expired products, infestation was found in 6.7%of rice flour and none was found in rice cereal-based infant food *** arthropods found in the flour samples were Cheyletus spp.,Suidasia pontifica(S. pontifica),Tarsonemus spp.,Tyrophagus putrescentiae(***),Sitophilus granarius(S. granarius) and Sitophilus oryzae(***).Others which cannot be identified were Oribatid and Prostigmatid *** most common mites in rice flour were Tarsonemus spp.(69.1%),followed by ***(18.2%).For expired products,only one sample of rice cereal-based infant food was infested and the infestation was by mites of the family ***:This study demonstrates the presence of 4 allergenic species of ***,***,*** and *** in rice *** arthropods can contribute to the incidence of anaphylaxis upon consumption by atopic *** was no infestation of arthropods in rice cereal-based infant food surveyed except for an expired product in a moderate rusty tin container.

关键词： Arthropods Mites Processed rice products

Study on accuracy of casting flow simulation

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China Foundry 2017年第5期14卷 333-338页

作者： Youngsim Choi Jun-ho hong ho-Young hwang Kyuhong Kim Dept.of Mechanical&Aerospace Engineering Seoul Nat.Univ.Republic of Korea Korea Institute of Industrial Technology(KITECH) Republic of Korea Institute of Advanced Aerospace Technology Seoul Nat.Univ.Republic of Korea

In the field of casting flow simulation, the application of body-fitted coordinate(BFC) has not been widely used due to the difficulty and low efficiency of grid generation, despite the availability of good quality analysis results. Cartesian coordinates, on the other hand, have been used predominantly in casting process simulations because of their relatively easy and fast grid generation. however, Cartesian grid systems cannot obtain accurate results because they cannot express the geometries properly. In this study, Cut Cell method was applied to solve this problem. The three-dimensional incompressible viscous governing equation was analyzed using a function defined for the volume and area of the casting in the cutting cell. Using the Cut Cell method, accurate flow analysis results were also obtained in the Cartesian grid systems. The tests of simple shape and the applications of actual casting product have been tried with Cut Cell method.

关键词： casting flow Cut Cell Cartesian coordinates body-fitted coordinates filling pattern conservationof momentum

Nutraceutical support for respiratory diseases

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Food Science and Human Wellness 2018年第3期7卷 205-208页

作者： Yu-Ya hwang Yuan-Soon ho Graduate Institute of Medical Sciences College of MedicineTaipei Medical UniversityTaipei 10031TaiwanChina

Respiratory diseases have been a major health concern for human beings since several *** the irritated nasal passages and airways had been a mutual necessity in multiple ancient *** ancient China,herbs were largely used to help deal with cough and reduce mucus,thereby maintaining respiratory *** India,knowledge of herb-related remedies passed down through *** the human society,freshly prepared herb ointments,including air-dried herbs,and boiled herbal soups have had a long history of combining botanical nutrients with local *** the use of herbs and natural products from plants(NPFPs)has been primarily cited in reviews based on modern respiratory diseases,the concept of soothing and alleviating disease progression or reducing mucus production has been highly ***,only a few herbs could directly disrupt the irreversible fibrotic *** the other hand,natural products from animals(NPFAs)have more potential in disrupting procollagen or extracellular matrix *** to these reasons,NPFAs could be considered as important functional foods for patients with respiratory *** this article,we provide a review of both NPFAs and NPFPs that are adjuvant to respiratory health.

关键词： Respiratory disease NPFP NPFA Nutrition Antioxidants

Diagnosis parameters of mold filling pattern for optimization of a casting system

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China Foundry 2012年第4期9卷 376-380页

作者： Jun-ho hong Young-Sim Choi ho-Young hwang e-Design Center Korea Institute of Industrial Technology e-Design Center Korea Institute of Industrial TechnologyIncheonKorea

For optimal design of a gating system,the setting of diagnosis parameters is very *** this study,the permanent mold casting process was selected because most of the other casting processes have more complicated factors that influence the mold filling pattern compared to the permanent mold casting process,such as the surface roughness of mold,gas generation from the mold wash and binder of sand mold,and the gas permeability through a sand mold,*** diagnosis parameters(flow rate difference and arrival time difference) of molten metal flow pattern in the numerical simulation are suggested for design of an optimum casting system with a permanent *** results show that the arrival time difference can be used as one important diagnosis parameter of the complexity of the runner system and its usefulness has been verified via making aluminum parts using permanent mold casting(Fig.9).

关键词： mold filling pattern optimum casting system diagnosis parameter permanent mold casting process

Polygonal multi-polymorphed Li4Ti5Oi2@rutile TiO2 as anodes in lithium-ion batteries

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Nano Research 2019年第4期12卷 897-904页

作者： Chang Hyun hwang Hee-eun Kim Inho Nam Jin ho Bang Department ofBionano Technology Hanyang University 55 Hanyangdaehak-ro Sangnok-gu Ansan Gyeonggi-do 15588 Republic of Korea School of Chemical Engineering & Materials Science Chung-Ang University 84 Heukseok-ro Dongjak-gu Seoul 06974 Republic of Korea Department of Chemical and Molecular Engineering Hanyang University 55 Hanyangdaehak-ro Sangnok-gu Ansan Gyeonggi-do 15588 Republic of Korea

Li4Ti50i2 (LTO) has attracted considerable attention in lithium-ion battery (LIB) applications because of its favorable characteristics as an anode material. Despite its promise, the widespread use of LTO is still limited primarily due to its intrinsically poor electric and ionic con ductivities and high surface reactivity. To address these issues, we desig ned polyg onal nano architectures composed of various Li-Ti oxide crystal polymorphs by a facile synthesis route. Depending on the pH condition, this synthesis approach yields multi-polymorphed Li-Ti oxides where the interior is dominantly composed of a Li-rich phase and the exterior is a Li-deficient (or Li-free) phase. As one of these variations, a polygonal LTO-rutile TiO2 structure is formed. The rutile TiO2 on the surface of this LTO composite significantly improves the kinetics of Li^+ insertion/extraction because the channel along the o-axis in TQ2 provides a Li^+ highway due to the significantly low energy barrier for Li^+ diffusion. Moreover, the presenee of rutile TiO2, which is less reactive with a carbonate-based electrolyte, ensures Iong-term stability by suppress)ng the undesirable interfacial reaction on LTO.

关键词： micro-polygon structure Li-Ti oxide multi-polymorphs Li4Ti5Oi2@ rutile TiO2 anode lithium-ion batteries