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Pathological,immunohistochemical and microbiologicalal analysis of lacrimal sac biopsies in patients with chronic dacrocystitis

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International Journal of Ophthalmology(English edition) 2013年第6期6卷 817-826页

作者： Rowayda Mahmoud Amin Faten Aly Hussein hisham farouk idriss Nesrine Fathy Hanafy Dina Mohamed Abdallah Department of Ophthalmology Alexandria Faculty of Medicine Department of Microbiology Alexandria Faculty of Medicine Department of Pathology Alexandria Faculty of Medicine

AIM:To analyze cases of obstruction of the nasolacrimal duct which creates a fertile environment for secondary bacterial Infection and can result in dacryocystitis,which is a constant threat to cornea and orbital soft tissue and a potential source of endophthalmitis following intraocular *** majority of obstructions of the lacrimal excretory outflow system are acquired ones occurring in adulthood and involving the distal parts of the *** obstruction may be primary/idiopathic or secondary to a wide variety of infectious,inflammatory,traumatic,mechanical,toxic or neoplastic causes mimicking idiopathic *** cases are treated by dacryocystorhinostomy(DCR).METHODS:The present study was conducted to determine the histopathologic,immunohistochemical and current microbiologic characteristics of lacrimal sac specimens in patients undergoing external ***:Non-specific lacrimal sac pathology was present in all 33 cases and 81.8%of the cases showed moderate chronic inflammation with a chronic inflammatory score(CIS)ranging between 4 and 6,whereas 12.12%showed severe inflammatory changes with a CIS of *** degree of inflammation was seen in6.06%with a CIS of *** total prevalence of grampositive,gram-negative,and culture-negative samples were 59.4%,37.5%,and 3%***:Non-specific chronic inflammation withfibrosis is indeed the most commonly reported histopathological finding in lacrimal sac wall biopsy specimens.

关键词： dacrocystitis lacrimal sac biopsy chronic inflammation lacrimal duct obstruction

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