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Basket pattern blood flow signals discovered in a case of splenic hamartoma by power Doppler ultrasonography

World Journal of Gastroenterology 2005年第33期11卷 5235-5238页

作者： Shigeo Nakanishi Katsuya Shiraki Kouji Yamamoto Takeshi Nakano Mutsumi Koyama Takatsugu Yano Takayuki Sanda hisao tamaki Tadanori Hirano Kazuo Fukudome Akinori Ishihara First Department of Internal Medicine Mie University School of Medicine Tsu Mie 514-8507 Japan Department of Internal Medicine Matsusaka General Hospital Matsusaka Mie 102 Japan First Department of Internal Medicine Mie University School of Medicine TsuMie 514-8507Japan Department of Internal Medicine Matsusaka General Hospital Matsusaka Mie 102 Japan Department of Surgery Matsusaka General Hospital Matsusaka Mie 102 Japan Tadanori Hirano Department of Radiology Matsusaka General Hospital Matsusaka Mie 102 Japan First Department of Internal Medicine Mie University School of Medicine Tsu Mie 514-8507 Japan Department of Pathology Matsusaka General Hospital Matsusaka Mie 102 Japan

We present the gray-scale ultrasonography （GSUS）, power Doppler ultrasonography （PDUS）, abdominal computed tomography （CT）, and magnetic resonance imaging （MRI） findings for a case of splenic hamartoma in a 27-year-old man, showing a φ 50 mm homogeneous, iso- and hypo-echoic splenic mass with evidence of a small plural cystic lesion. This splenic hamartoma showed increased vascularity on power Doppler sonograms. PDUS showed multiple circular blood flow signals inside the mass （i.e. a basket pattern）, which was consistent with the small plural cystic lesion shown by GSUS. Spectral analysis also confirmed arterial and venous flow. CT scans showed that the mass had lowdensity relative to the normal spleen and MRI showed that the mass was isodense, relative to the normal spleen. Therefore, CT and MRI are not useful for the diagnosis of splenic hamartoma. Ultrasonography can be used to diagnose splenic hamartoma without administration of a contrast matedal and therefore is an indispensable method for the diagnosis of splenic hamartoma.

关键词： Splenic hamartoma Ultrasonography Basketpattern

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Renal Cell Carcinoma Associated with Xp11.2 Translocation/TFE3 Gene Fusion: A Case Report with Immunohistochemical and Cytological Features

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Open Journal of Pathology 2016年第1期6卷 19-25页

作者： Takuji Tanaka Kuniaki Hirai Fumimasa Etori Masashi Matsuyama Naoki Watanabe Hiromi Kondo Masayoshi tamaki Tatsuya Yamashita Shiho Yasue Mika Noda Kunihiro Shinoda hisao Komeda Department of Diagnostic Pathology (DDP) & Research Center of Diagnostic Pathology (RC-DiP) Gifu Municipal Hospital Gifu Japan Department of Radiology Ehime University Graduate School of Medicine Ehime Japan Department of Urology Gifu Municipal Hospital Gifu Japan Department of Pediatrics Gifu Municipal Hospital Gifu Japan

Gene fusions involving two of the MiT subfamily factors, such as TFE3, TFEB, TFC and MiTF, have been identified in renal cell carcinoma (RCC). Xp11.2 translocation RCC is a rare pediatric neoplasm that harbors gene fusions involving TFE3, which plays an important role in cell proliferation and survival. We herein present a case of RCC associated with Xp11.2 translocation/TFE3 gene fusion in a 14-year-old Japanese boy presenting gross hematuria and body weight loss. The tumor was characterized by histopathology, cytology and TFE3-immunohistochemistry/immunocytochemistry. Knowledge of distinctive morphological and immunostaining features of this tumor can help to accurately diagnose this rare subset of translocation associated RCC in routine pathological diagnostic procedures.

关键词： Renal Cell Carcinoma Xp11.2 Translocation TFE3 Cytology Immunohistochemistry Immunocytochemistry

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