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New approach to resolve the amount of Quaternary uplift and associated denudation of the mountain ranges in the Japanese Islands

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Geoscience Frontiers 2016年第2期7卷 197-210页

作者： Shigeru Sueoka hiroyuki tsutsumi Takahiro Tagami Japan Atomic Energy Agency 2-1 Shiraki Tsuruga Fukui 919-1279 Japan Department of Geophysics Division of Earth and Planetary Sciences Kyoto University Oiwake-cho Kitashirakawa Sakyo-ku Kyoto 606-8502 Japan Department of Geology and Mineralogy Division of Earth and Planetary Sciences Kyoto University Oiwake-cho Kitashirakawa Sakyo-ku Kyoto 606-8502 Japan

Low-temperature thermochronology is a widely used tool for revealing denudation histories of mountain ranges. Although this technique has been applied mainly to continental orogens, such as the European Alps, Himalayas, and Andes, recent technological development of low-temperature thermochronology has made it applicable to a wider variety of mountain ranges with various sizes and tectonic histories. The Japanese Islands comprise young and active island arcs, where an early stage of mountain range formation is observed. Numerous attempts have been made to constrain the uplift and denudation histories of the mountains in the Japanese Islands using geologic, geomorphologic, or geodetic methods. However, the number of thermochronometric attempts has been limited primarily due to the small amount of total denudation since the initiation of the uplift. In this review paper, we introduce the tectonic and geomorphic settings of the mountain ranges in the Japanese Islands, and discuss previous attempts to estimate uplift or denudation of the Japanese mountains using methods other than ther- mochronology. Furthermore, we discuss problems of the thermochronometric applications in revealing denudation histories of the Japanese mountains. Finally, we present a case study of the Kiso Range in central Japan and discuss the current effectiveness and applicability of low-temperature thermochronology to the Japanese mountainous areas.

关键词： Low-temperature thermochronology Denudation Japanese Islands Fault-block mountain T-d relationships

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西南日本四国中部中央构造线全新世断层作用的发生时间和位移

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地震地质译丛 1992年第5期14卷 19-24页

作者： hiroyuki tsutsumi 程绍平杨桂枝

探槽附近的地貌学和地质学沿冈村断裂迹线的右旋水系断错和构造隆起显示出位移以左旋分量为主。同时,北盘的晚第四纪阶地累积下沉。我们在冈村断层中段的一个小断层陡坎的麓部横跨断层进行了开挖,这个陡坎致使一个更新世的河流阶地发生... 详细信息

探槽附近的地貌学和地质学沿冈村断裂迹线的右旋水系断错和构造隆起显示出位移以左旋分量为主。同时,北盘的晚第四纪阶地累积下沉。我们在冈村断层中段的一个小断层陡坎的麓部横跨断层进行了开挖,这个陡坎致使一个更新世的河流阶地发生断错。虽然这个小断层陡坎在现今冲积扇上没有任何的地形显示,但是,我们根据它的直线连续性推测出冈村断层迹线的位置。该探槽地点以南的地质学由白垩系的和泉组(砂岩)、上新统的冈村建造(含有结晶片岩砾石的砂质粉砂)、第四系中阶地沉积物(以砂充填的片岩砾石—巨砾)、和第四系低阶地沉积物(以砂富集的砂岩砾石—大砾) (图1)。冈村建造和第四纪中阶地沉积物中的砾石层组成物为片岩砾石,它们来源于地质上特殊的中央构造线以南的三波川变质岩。但是,第四纪低阶地沉积物中的砾石层由和泉组砂岩砾石组成。河谷 A、B 和 C(图1)提供了不同类型的砾石,这些砾石与它们源头地质学有关。河谷 A 主要提供片岩砾石,河谷 B 提供片岩和砂岩两种砾石,以及河谷 C 主要提供砂岩砾石。因为开挖探槽的冲积扇组成物质来源于河谷A,所以,探槽的大部分沉积物中均含有片岩砾石。探槽中有一些层位含有可能来源于河谷B和 C 的砂岩砾石,它们作为参照层来计算水平滑动速度。

关键词：全新世断层作用构造线日本西南

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High-density circulating fluidized bed gasifier for advanced IGCC/IGFC-Advantages and challenges

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Particuology 2010年第6期8卷 602-606页

作者： Guoqing Guan Chihiro Fushimi Atsushi tsutsumi Masanori Ishizuka Satoru Matsuda hiroyuki Hatano Yoshizo Suzuki Collaborative Research Center for Energy Engineering Deportment of Mechanical and Biolhnctional Systems Institute of Industrial Science The University of Tokyo 4-6-1 Komaba Meguoro-ku Tokyo 153-8505Japan Clean Gas Group National Institute of Advanced Industrial Science and Technology 16- 1 Onogawa Tsukuba Iboraki 305-8569Japan

Coal-fired Integrated Gasification Combined Cycle （IGCC） and Integrated coal Gasification Fuel-cell Com- bined cycle （IGFC） are being developed as high-efficiency electric power generation technology. However, the highest theoretical gross thermal efficiency of the conventional IGCC]IGFC is still below 52~. In order to obtain higher power generation efficiency, an advanced IGCC （A-IGCC） or advanced IGFC （A-IGFC） sys- tem making use of the exergy recuperation concept by recycling waste heat from gas turbine or fuel cells for steam gasification of coal and biomass was proposed in our laboratory, Corresponding to this system, a novel high-density triple-bed combined circulating fluidized bed （TBCFB） gasifier, composed of a downer pyrolyzer, a bubbling fluidized bed char gasifier, and a riser combustor, was proposed to replace traditional gasifiers such as the entrained flow bed gasifier. The new system is expected to more effectively utilize the waste heat from gas turbines or fuel cells and the heat produced by the combustion of the unreacted char in the riser combustor for pyrolysis and gasification of coal and biomass. In this short review, the advantages and future challenges in the development of high-density TBCFB gasifier are presented and discussed.

关键词： IGCC/IGFC High-density circulating fluidized bed Gasifier Riser Downer Bubbling fluidized bed Exergy recuperation Biomass Coal

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Extracapsular invasion as a risk factor for disease recurrence in colorectal cancer

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World Journal of Gastroenterology 2011年第15期17卷 2003-2006页

作者： Takaaki Fujii Yuichi Tabe Reina Yajima Satoru Yamaguchi Soichi tsutsumi Takayuki Asao hiroyuki Kuwano Depart ment of General Surgical Science Graduate School of Medicine Gunma University Gunma 371-8511 Japan

AIM: To evaluate the presence of extracapsular invasion (ECI) in positive nodes as a predictor of disease recurrence disease in colorectal cancer. METHODS: Two hundred and twenty-eight consecutive patients who underwent colorectal resection were identified for inclusion in this study, of which 46 had positive lymph nodes. Among 46 cases with stage Ⅲcolorectal cancer, 16 had ECI at positive nodes and 8 had disease recurrence. The clinical and pathological features of these cases were reviewed. RESULTS: In the univariate analysis, the number of positive lymph nodes and depth of tumor invasion were significantly associated with the presence of ECI at positive nodes. Multivariate analysis demonstrated that only ECI was a predictor of recurrence. The recurrence-free interval differed significantly among patients with ECI at positive ***: Our results suggest that ECI at metastatic nodes can identify which cases are at high risk of short-term disease recurrence in colorectal cancer.

关键词： Extracapsular invasion Lymph node Metastasis Colorectal cancer Risk factor Adjuvant therapy

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Partial stent-in-stent placement of biliary metallic stents using a short double-balloon enteroscopy

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World Journal of Gastroenterology 2012年第45期18卷 6674-6676页

作者： Koichiro tsutsumi Hironari Kato Takeshi Tomoda Kazuyuki Matsumoto Ichiro Sakakihara Naoki Yamamoto Yasuhiro Noma Takayuki Sonoyama hiroyuki Okada Kazuhide Yamamoto Department of Gastroenterology and Hepatology Dentistry and Pharmaceutical SciencesOkayama University Graduate School of MedicineOkayama 700-8558Japan

Endoscopic intervention is less invasive than percutaneous or surgical approaches and should be considered the primary drainage procedure in most cases with obstructive ***,therapeutic endoscopic retrograde cholangiopancreatography(ERCP) using double-balloon enteroscopy(DBE) has been shown to be feasible and effective,even in patients with surgically altered *** the other hand,endoscopic partial stent-in-stent(PSIS) placement of selfexpandable metallic stents(SEMSs) for malignant hilar biliary obstruction in conventional ERCP has also been shown to be feasible,safe and *** performed PSIS placement of SEMSs for malignant hilar biliary obstruction due to liver metastasis using a short DBE in a patient with Roux-en-Y anastomosis and achieved technical and clinical *** procedure can result in quick relief from obstructive jaundice in a single session and with short-term hospitalization,even in patients with surgically altered anatomies.

关键词： Double-balloon enteroscopy Malignant hi-lar biliary obstruction Self-expandable metallic stent Partial stent in stent Roux-en-Y anastomosis

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Clinical differences between alcoholic liver disease and nonalcoholic fatty liver disease

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World Journal of Gastroenterology 2014年第26期20卷 8393-8406页

作者： Nobuyuki Toshikuni Mikihiro tsutsumi Tomiyasu Arisawa Department of Gastroenterology Kanazawa Medical University Department of Hepatology Kanazawa Medical University

Alcoholic liver disease(ALD)and nonalcoholic fatty liver disease(NAFLD)are serious health problems *** two diseases have similar pathological spectra,ranging from simple hepatic steatosis to steatohepatitis,liver cirrhosis,and hepatocellular *** most subjects with excessive alcohol or food intake experience simple hepatic steatosis,a small percentage of individuals will develop progressive liver ***,both ALD and NAFLD are frequently accompanied by extrahepatic complications,including cardiovascular disease and *** survival of patients with ALD and NAFLD depends on various disease-associated *** review delineates the clinical characteristics and outcomes of patients with ALD and NAFLD by comparing their epidemiology,the factors associated with disease susceptibility and progression,and the predictors and characteristics of outcomes.A comprehensive understanding of the characteristics and outcomes of ALD and NAFLD is imperative in the management of these chronic liver diseases.

关键词： Alcoholic liver disease Nonalcoholic fatty liver disease Clinical characteristics Outcomes Chronic liver disease

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Petrology,geochemistry,and zircon U-Pb geochronology of the Zambezi Belt in Zimbabwe:Implications for terrane assembly in southern Africa

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Geoscience Frontiers 2019年第6期10卷 2021-2044页

作者： Yusuke Kuribara Toshiaki Tsunogae Yusuke Takamura Yukiyasu tsutsumi Graduate School of Life and Environmental Sciences University of TsukubaIbaraki 305-8572Japan Department of Geology University of JohannesburgAuckland Park 2006South Africa Department of Geology and Paleontology National Museum of Nature and ScienceIbaraki 305-0005Japan

The Zambezi Belt in southern Africa has been regarded as a part of the 570-530 Ma Kuunga Orogen formed by a series of collision of Archean cratons and Proterozoic orogenic ***,we report new petrological,geochemical,and zircon U-Pb geochronological data of various metamorphic rocks(felsic to mafic orthogneiss,pelitic schist,and felsic paragneiss)from the Zambezi Belt in northeastern Zimbabwe,and evaluate the timing and P-T conditions of the collisional event as well as protolith *** data of felsic orthogneiss indicate within-plate granite signature,whereas those of mafic orthogneiss suggest MORB,ocean-island,or within-plate *** P-Testimates for orthogneisses indicate significant P-T variation within the study area(700-780 C/6.7-7.2 kbar to 800-875 C/10-11 kbar)suggesting that the Zambezi Belt might correspond to a suture zone with several discrete crustal *** cores from felsic orthogneisses yielded two magmatic ages:2655±21 Ma and 813士5 Ma,which suggests Neoarchean and Early Neoproterozoic crustal growth related to within-plate *** zircons from metasediments display various ages from Neoarchean to Neoproterozoic(ca.2700-750 Ma).The Neoarchean(ca.2700-2630 Ma)and Paleoproterozoic(ca.2200-1700 Ma)zircons could have been derived from the adjacent Kalahari Craton and the Magondi Belt in Zimbabwe,*** Choma-Kalomo Block and the Lufilian Belt in Zambia might be proximal sources of the Meso-to Neoproterozoic(ca.1500-950 Ma)and early Neoproterozoic(ca.900-750 Ma)detrital zircons,*** detrital zircons from adjacent terranes possibly deposited during late Neoproterozoic(744-670 Ma),and subsequently underwent highgrade metamorphism at 557-555 Ma possibly related to the collision of the Congo and Kalahari Cratons during the latest Neoproterozoic to *** contrast,670-627 Ma metamorphic ages obtained from metasediments are slightly older than previous reports,but consistent with^68

关键词： Geothermobarometry Detrital zircon Neoproterozoic Congo Craton Kalahari Craton Gondwana

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Nutrition and exercise in the management of liver cirrhosis

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World Journal of Gastroenterology 2014年第23期20卷 7286-7297页

作者： Nobuyuki Toshikuni Tomiyasu Arisawa Mikihiro tsutsumi Department of Gastroenterology Kanazawa Medical UniversityIshikawa 920-0293Japan Department of Hepatology Kanazawa Medical UniversityIshikawa 920-0293Japan

Liver cirrhosis(LC)patients often have protein-energy malnutrition(PEM)and decreased physical *** conditions often lead to sarcopenia,which is the loss of skeletal muscle volume and increased muscle *** studies have demonstrated that PEM and sarcopenia are predictors for poor survival in LC *** and exercise management can improve PEM and sarcopenia in those *** management includes sufficient dietary intake and improved nutrient *** the current high prevalence of obesity,the number of obese LC patients has increased,and restriction of excessive caloric intake without the exacerbation of impaired nutrient metabolism is required for such *** chain amino acids are good candidates for supplemental nutrients for both obese and non-obese LC *** management can increase skeletal muscle volume and strength and improve insulin resistance;however,nutritional status and LC complications should be assessed before an exercise management regimen is implemented in LC *** establishment of optimal exercise regimens for LC patients is currently *** this review,we describe nutritional status and its clinical impact on the outcomes of LC patients and discuss general nutrition and exercise management in LC patients.

关键词： Liver cirrhosis Protein-energy malnutrition Sarcopenia Obesity Exercise

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World Journal of Gastroenterology 2014年第11期20卷 2876-2887页

Liver cirrhosis (LC) is a critical stage of chronic liver disease, including that caused by hepatitis C virus (HCV). In the absence of antiviral therapy, 67%-91% of patients with HCV-related LC patients die of liver-related causes, including hepatocellular carcinoma (HCC) and liver failure. Among the therapeutic strategies used to prevent liver-related complications in these patients is standard therapy with pegylated interferon and ribavirin, which induces a sustained virological response (SVR) in 25% of HCV genotype 1-infected patients and in 69% of patients infected with genotypes 2 and 3. SVR in patients with HCV-related LC has been associated with reduced rates of hepatic decompensation, HCC, and mortality. More recently developed direct-acting antiviral agents have shown excellent antiviral efficacy, with preliminary data demonstrating that an interferon-free regimen that includes these direct-acting antiviral agents achieved SVR in more than 50% of patients with HCV genotype 1 LC. Branched-chain amino acid supplementation, improvement of insulin resistance, and the use of β-blockers for portal hypertension may also reduce liver-related complications. Here, we review advances in antiviral and adjunctive therapies for improved outcomes in patients with HCV-associated LC.

关键词： Hepatitis C virus Liver cirrhosis Hepatic decompensation Hepatocellular carcinoma Mortality Prevention Interferon Direct-acting antiviral agents

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Successful biliary drainage using a metal stent through the gastric stoma

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World Journal of Gastroenterology 2015年第24期21卷 7594-7597页

作者： Kazuyuki Matsumoto Hironari Kato Koichiro tsutsumi Yutaka Akimoto Daisuke Uchida Takeshi Tomoda Naoki Yamamoto Yasuhiro Noma Shigeru Horiguchi hiroyuki Okada Kazuhide Yamamoto Department of Gastroenterology and Hepatology Okayama University Graduate School of Medicine Dentistry and Pharmaceutical Sciences

We report a case of biliary drainage for malignant stricture using a metal stent with an ultrathin endoscope through the gastric stoma. A 78-year-old female was referred to our hospital for jaundice and fever. She had undergone percutaneous endoscopic gastrostomy(PEG) for esophageal obstruction after radiation therapy for cancer of the pharynx. Abdominal contrast-enhanced computed tomography showed a 3-cm enhanced mass in the middle bile duct and dilatation of the intrahepatic bile duct. We initially performed endoscopic retrograde cholangiopancreatography(ERCP) with a trans-oral approach. However, neither the side-viewing endoscope nor the ultrathin endoscope passed through the esophageal orifice. Thus, we eventually performed ERCP via the PEG stoma using an ultrathin endoscope. We performed biliary drainage with a 6F introducer selfexpanding metal stent. The cytology findings obtained by brush cytology showed malignancy. Her laboratory results were restored to normal levels after drainage and no complication occurred.

关键词： Percutaneous endoscopic gastrostomy Transgastrostomic endoscopy Ultrathin endoscope Malignant biliary obstruction Metal stent

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