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Spleen-preserving distal pancreatectomy with conservation of the splenic artery and vein

World Journal of Gastroenterology 2007年第10期13卷 1493-1499页

作者： Wataru Kimura Toshiyuki Moriya Jinfeng Ma Yukinori Kamio Toshihiro Watanabe Mitsukiro Yano hiroto fujimoto Koji Tezuka Ichiro Hirai Akira Fuse Gastroenterological and General Surgery (First Department of Surgery)Yamagata University School of Medicine2-2-2 Iida-NishiYamagata CityYamagata 990-9585Japan

PreservaUon of the spleen at distal pancreatectomy has recently attracted considerable attention. Since our first successful trial, spleen-preserving distal pancreatectomy with conservation of the splenic artery and vein for tumors of the pancreas and chronic pancreatitis has been performed more frequently. The technique for spleenpreserving distal pancreatectomy with conservation of the splenic artery and vein are outlined. The splenic vein is identified behind the pancreas and within the thin connective tissue membrane. The connective tissue membrane is cut longitudinally above the splenic vein. An important issue is to remove the splenic vein from the body of the pancreas toward the spleen, since a different approach may be very difficult. The pancreas is preferably removed from the splenic artery toward the head of the pancreas itself. This procedure is much easier than removing the pancreas from the vein side. One patient had undergone distal gastrectomy for duodenal ulcer, with reconstruction by Billroth Ⅱ tehcnique. If distal pancreatectomy with splenectomy had been performed for the lesion of the distal pancreas at the time, the residual stomach would also have to be resected. The potential damage done to the patient by reconstruction of the gastrointestinal tract in combination with distal pancreatectomy and splenectomy would have been much greater than with distal pancreatectomy only with preservation of the spleen and residual stomach. Benign lesions as well as low-grade malignancy of the body and tail of the pancreas may be a possible indication for this procedure.

关键词： Spleen preservation Intraductal Papillary-Mucinous Neoplasm Splenic artery Splenic vein The fusion fascia of Treitz and Toldt

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Challenge to ABO blood type barrier in living donor liver transplantation

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Hepatobiliary & Pancreatic Diseases International 2020年第4期19卷 342-348页

作者： hiroto Egawa Department of Gastroenterology Tokyo Women’s Medical UniversityTokyoJapan

ABO incompatible living donor liver transplantation has the potential to expand the donor pool for patients with end stage liver diseases on the expense of challenges to overcome immunological barriers across blood *** is a profound impact of age on incidence and severity of antibody mediated rejection(AMR).Even children older than 1 year have chances of AMR;children aged 8 years or older have risks of hepatic necrosis similar to adult liver *** mechanism of AMR is based on circulatory disturbances secondary to inflammation and injury of the vascular endothelium caused by an antibody-antigen-complement *** strategy to overcome ABO blood type barrier is based on both pre-transplant desensitization and adequate treatment of this ***,rituximab is the standard means of desensitization but unfortunately an insufficient aid to treat *** of low incidence(less than 5%in the rituximab era),in practice of AMR only some case reports about the treatment of clinical AMR are available in the *** experiences revealed that the proteasome inhibitor,bortezomib might be a promising treatment based on its capacity to deplete plasma cell *** ABO blood type barrier has been counteracted in 95%of patients by applying“rituximab-desensitization”,many issues,such as prediction of high-risk patients of infection and AMR and secure treatment strategies for evoked AMR,remain to be resolved.

关键词： ABO blood type Living donor liver transplantation Antibody mediated rejection

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Autoimmune hepatitis triggered by acute hepatitis A

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World Journal of Gastroenterology 2005年第38期11卷 6069-6071页

作者： hiroto Tanaka hiroto Tujioka Hiroki Ueda Hiroko Hamagami Youhei Kida Masakazu Ichinose 3rd Department of Internal Medicine

The patient was a 57-year-old woman presenting with jaundice as the chief complaint. She began vomiting on July 10, 2003. Jaundice was noted and admitted to our hospital for thorough testing. Tests on admission indicated severe hepatitis, based on： aspartate aminotransferase （AST）, 1 076 IU/L; alanine aminotransferase （ALT）, 1 400 IU/L; total bilirubin （TB）, 20.9 mg/dL; and prothrombin time rate （PT%）, 46.9%. Acute hepatitis A （HA） was diagnosed based on negative hepatitis B surface antigen and hepatitis C virus RNA and positive immunoglobulin （Ig） M HA antibody, but elevation of anti-nuclear antigen （×320） and IgG （3 112 mg/dL） led to suspicion of autoimmune hepatitis （AIH）. Plasma exchange was performed for 3 d from July 17, and steroid pulse therapy was performed for 3 d starting on July 18, followed by oral steroid therapy. Liver biopsy was performed on August 5, and the results confirmed acute hepatitis and mild chronic inflammation. Levels of AST and ALT normalized, so dose of oral steroid was markedly reduced. Steroid therapy was terminated after 4 mo, as the patient had glaucoma. Starting 3 mo after cessation of steroid therapy, levels of AST and ALl began to increase again. Another liver biopsy was performed and AIH was diagnosed based on serum data and biopsy specimen. Oral steroid therapy was reinitiated. Levels of AST and ALT again normalized. The present case was thus considered to represent AIH triggered by acute HA.

关键词： Acute hepatitis A Autoimmune hepatitis International criteria for AIH HLA

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Improvement of a temperature response function for divertor heat flux monitoring in fusion devices

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Plasma Science and Technology 2023年第3期25卷 217-221页

作者： Xuan Nhat Son BUI hiroto MATSUURA Yousuke NAKASHIMA Quantum and Radiation Engineering Department Osaka Prefecture University Plasma Research Center University of Tsukuba

Temperature response functions have been developed to investigate sensor design and divertor heat flux estimation in magnetically confined plasmas. The time-dependent heat flux can be derived by fitting the response function to experimental thermocouple(TC) data. Because the TC signals have a time delay to transit events such as discharge start or confinement transition, the time delay is taken into account in a temperature response function. Such a function accurately describes the signal from each TC channel with time delay in a sensor test using a neutral beam injection. Measurement for commercial TCs shows that the time delay is caused by the finite heat capacity of TC wire and contact heat resistance between TC and target surface.

关键词： divertor temperature response function thermocouple system primary delay

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Platinum–P(BFPy) 3 -catalyzed regioselective diboration of terminal alkynes with (pin)B–B (aam)

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Organic Chemistry Frontiers 2022年第5期9卷 1370-1374页

作者： Ikuo Kageyuki Jialun Li hiroto Yoshida Graduate School of Advanced Science and Engineering Hiroshima UniversityHigashi-Hiroshima 739-8526Japan

An unsymmetrical diboron,(pin)B–B(aam),is smoothly added across a carbon–carbon triple bond of various terminal alkynes under platinum catalysis,resulting in the regio-and stereoselective formation of cis-vic-diborylalkenes via B(aam)-installation at the terminal *** use of a highly electron-deficient triarylphosphine ligand,P(BFPy)_(3),is indispensable for the regiocontrol,and electron-deficiency in ligands has been proven to be closely correlated with the regioselectivity.

关键词： smoothly catalyzed boron

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Effect of insulating oil covering electrodes on the characteristics of a dielectric barrier discharge

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Plasma Science and Technology 2020年第11期22卷 36-41页

作者： Trung Nguyen TRAN Bounyang OANTHAVINSAK Shinichiro KADO hiroto MATSUURA Department of Quantum and Radiation Engineering Graduate School of EngineeringOsaka Prefecture UniversitySakaiOsaka 599-8570Japan Institute of Advanced Energy Kyoto UniversityUjiKyoto 611-0011Japan

In this study,the effects of the fluid cooling and electric field line deformation were investigated in a dielectric barrier discharge(DBD)plasma *** DBD plasma jet is improved by covering the ground electrode and a power electrode with insulating *** obtained positive results as insulating oil prevents arc formation,while it improved the supplied power and plasma jet length,and increased radical *** production of this nonthermal plasma jet is studied with polyvinyl alcohol-potassium iodide liquid.

关键词： atmospheric pressure plasma jet APPJ Lissajous figure dielectric barrier discharge plasma plume

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Algicidal effect of bacterial isolates of Pedobacter sp. against cyanobacterium Microcystis aeruginosa

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Water Science and Engineering 2012年第4期5卷 375-382页

作者： Li YANG hiroto MAEDA Takeshi YOSHIKAWA Gui-qin ZHOU College of Environment Hohai University College of Environment Nanjing University of Technology Laboratory of Microbiology Faculty of FisheriesKagoshima University

The aim of this study was to isolate algicidal bacteria so as to control harmful cyanobacterium Microcystis aeruginosa （M. aeruginosa） blooms using biological methods. Nine bacterial strains were isolated to inhibit the growth ofM. aeruginosa, among which the Mail 1-5 bacterial strain exhibited remarkable algicidal activity against M. aeruginosa cells during the test. Based on the 16S rDNA analysis, the isolated Mail 1-5 was identified as Pedobacter sp. through morphology and homology research. The results of cocultivation of the cyanobacteria with MaI 11-5 algicidal isolates showed obvious algicidal activity against cyanobacterial cells. The algicidal effect of Mail 1-5 exceeded 50% after two days, exceeded 70% after four days, and reached 80% after seven days. The observation results with a scanning electron microscope showed that the cyanobacterial cells aggregated and produced mucous-like substances when cocultivated with the algicidal bacteria. The results indicated that the Mail 1-5 bacterial strain may possess a novel function for controlling harmful blooms and further studies will provide new insights into its role in water environment.

关键词： algicidal bacteria Pedobacter sp. algicidal effect Microcystis aeruginosa

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Morphology Effects of Leading-edge Serrations on Aerodynamic Force Production： An Integrated Study Using PIV and Force Measurements

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Journal of Bionic Engineering 2018年第4期15卷 661-672页

作者： Teruaki Ikeda Tetsuya UedA Toshiyuki Nakata Ryusuke NodA hiroto Tanaka Takeo Fujii Hao Liu Graduate School of Engineering Chiba University 1-33 Yayoi-cho lnage-ku Chiba-shi Chiba 263-8522 Japan TERAL Inc. 230 Moriwake Miyuki-cho Fukuyama-shi Hiroshima 720-0003 Japan School of Engineering Tokyo Institute of Technology 2-12-10okayama Meguro-ku Tokyo 152-8550 Japan Shanghai Jiao Tong University and Chiba University International Cooperative Research Centre (SJTU-CU ICRC) Shanghai 200240 China

While the leading-edge serration in owls＇ wing is known to be responsible for low noise gliding and flapping flights, the findings on its aero-acoustic role have been diverse or even controversial. Here we present an experimental study of the morphological effects of leading-edge serrations on aerodynamic force production by utilizing owl-inspired, single-feather, clean and serrated wing models with different serration lengths and spacing, and by combining Particle Image Velocimetry （PIV） and force measurements. Force measurements show that an increase in the length and density of the leading-edge serrations leads to a reduction in the lift coefficient and lift-to-drag ratio at Angles of Attack （AoAs）〈 15° whereas the clean and serrated wings achieve comparable aerodynamic performance at higher AoAs 〉 15°, which owl wings often reach in flight. Furthermore PIV visualization of the flow fluctuations demonstrates that the leading-edge serration-based mechanism is consistent in all serrated wing models in terms of passive control of the laminar-turbulent transition while at AoAs 〉 15° similar suction flow is present at leading edge resulting in a comparable aerodynamic performance to that of the clean wing. Our results indicate the robustness and usefulness of leading-edge serration-inspired devices for aero-acoustic control in biomimetic rotor designs.

关键词： biomimetic leading-edge serrations low-speed wind tunnel particle image velocimetry aerodynamic force lami-nar-turbulent transition

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Hepatic encephalopathy with status epileptics: A case report

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World Journal of Gastroenterology 2006年第11期12卷 1793-1794页

作者： hiroto Tanaka Hiroki Ueda Yohei Kida Hiroko Hamagami Tomikimi Tsuji Masakazu Ichinose The Third Department of Internal Medicine Wakayama Medical University 811-1 KimiideraWakayama City641-0015Japan the Department of Neuropsychology Wakayama Medical University 811-1 KimiideraWakayama City641-0015Japan

A 62-year-old male with decompensated liver cirrhosis due to hepatitis C virus developed severe hepatic encephalopathy with status epileptic us. The blood ammonia level on admission was more than twice the normal level. Brain computed tomography and magnetic resonance imaging were normal. In addition, electroencephalogram showed diffuse sharp waves, consistent with hepatic encephalopathy. The status epilepticus was resolved after antiepileptic therapy （phenytoin sodium） and treatment for hepatic encephalopathy （Branched chain amino acids）. The blood ammonia level normalized with the clinical improvement and the patient did not have a recurrence of status epilepticus after the end of the antiepileptic treatment. Additionally, the electroencephalogram showed normal findings. Thus, we diagnosed the patient as hepatic encephalopathy with status epilepticus. We consider the status epilepticus of this patient to a rare and interesting finding in hepatic encephalopathy.

关键词： Status epilepticus Hepatic encephalopathy Decompensated liver cirrhosis Electroencephalogram

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Accuracy of shoulder joint injections with ultrasound guidance:Confirmed by magnetic resonance arthrography

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World Journal of Orthopedics 2022年第3期13卷 259-266页

作者： Kosuke Kuratani Makoto Tanaka hiroto Hanai Kenji Hayashida Department of Orthopedic Surgery Japan Community Healthcare Organization Osaka HospitalOsaka 553-0003Japan Center for Sports Medicine Daini Osaka Police HospitalOsaka 543-8922Japan Department of Orthopaedic Surgery Osaka University Graduate School of MedicineSuita 565-0871Japan Department of Orthopaedic Surgery Daini Osaka Police HospitalOsaka 543-8922Japan

BACKGROUND Intra-articular glenohumeral joint injections are essential procedures for treating various shoulder disorders. Fluoroscopy-guided injections have been extensively used;however, they pose a risk of radiation exposure and are expensive and timeconsuming. Recently, it has been suggested that ultrasound-guided injections are accurate and cost effective *** To evaluate the accuracy of ultrasound-guided glenohumeral injections using a posterior approach that is confirmed using magnetic resonance arthrography(MRA).METHODS The study included 179 shoulders of patients with recurrent anterior instability(150 patients;103 and 76 right and left shoulders, respectively;160 males and 19 females;average age = 20.5 years;age range: 14-63 years) who underwent MRA for preoperative diagnosis. They were injected with 12 m L lidocaine(1%) using the ultrasound-guided posterior approach and then underwent magnetic resonance imaging. Two shoulder surgeons, except for the injector, evaluated the transverse relaxation(T2)-weighted images of axial planes and classified the intraarticular condition of injected contrast into three groups based on one of the three following scenarios: no leakage, injection into the glenohumeral joint without leakage;minor leakage, practical intra-articular injection with some leakage outside the posterior rotator cuffs;and major leakage, inaccurate injection with mass leakage without any contrast into the joint. The inter-rater reliability between two assessors was also evaluated by calculating Cohen’s kappa coefficient. The learning curve was assessed regarding the inaccurate injection rate by analyzing Spearman’s rank correlation *** Of the 179 injections, 163 shoulders(91.0%) had no leakage, 10 shoulders(5.6%) had minor leakage, and six shoulders(3.4%) had major leakage. In total, 173 shoulders(96.6%) were intraarticularly injected;thus, we could detect anterior labrum and capsular pathologies. Regarding the inter-rater

关键词： Shoulder injections Glenohumeral injections Ultrasound guidance Magnetic resonance arthrography

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