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太空和地面环境发育鸡胚的耳蜗神经节神经元形态比较

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郑州大学学报（医学版） 2004年第2期39卷 298-301页

作者：陈向东 Cesar D.Fermin Dale Martin hirotaka Hara Jun Hara 郑州大学第二附属医院耳鼻咽喉科 Department of Pathology & Laboratory Medicine Tulane UniversityNew OrleansLA 70112-2699USA Department of Otolaryngology Yamaguchi UniversityUbeYamaguchi 755Japan

目的:探讨太空微重力对鸡胚耳蜗神经元的形态发育有无影响。方法:随机选取太空发育鸡胚和地面发育鸡胚各2只,利用计算机显微测量技术测量耳蜗神经节神经元截面的面积、周长、形态系数,每只鸡胚测量200个神经元。结果:2只太空发育鸡胚的... 详细信息

目的:探讨太空微重力对鸡胚耳蜗神经元的形态发育有无影响。方法:随机选取太空发育鸡胚和地面发育鸡胚各2只,利用计算机显微测量技术测量耳蜗神经节神经元截面的面积、周长、形态系数,每只鸡胚测量200个神经元。结果:2只太空发育鸡胚的耳蜗神经元截面的面积分别为(109.62±22.56)μm2和(123.63±26.73)μm2,周长分别为(39.71±4.28)μm和(42.00±4.87)μm,形状系数分别为0.865 2±0.048 7和0.872 4±0.058 7。2只地面发育鸡胚的前庭神经元截面的面积分别为(118.22±26.82)μm2和(114.08±27.83)μm2,周长分别为(41.23±4.88)μm和(40.25±5.08)μm,形状系数分别为0.864 7±0.061 4和0.872 2±0.048 2。结论:本研究结果提示微重力对耳蜗神经元的形态发育可能无影响。

关键词：航天飞机鸡胚耳蜗神经节神经元微重力发育

Fast time-division color electroholography using a multiple-graphics processing unit cluster system with a single spatial light modulator

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Chinese Optics Letters 2017年第12期15卷 34-37页

作者： Hiromitsu Araki Naoki Takada Shohei Ikawa Hiroaki Niwase Yuki Maeda Masato Fujiwara hirotaka Nakayama Minoru Oikawa Takashi Kakue Tom oyoshi Shim obaba and Tom oyoshi Ito Graduate School of Integrated Arts and Sciences Kochi Universit y Kochi 780-8520 Japan Science Department Natural Sciences Cluster Research and Education Faculty Kochi University Kochi 780-8520 Japan Faculty of Science Kochi University Kochi 780-8520 Japan Center for Computational Astrophysics National Astronomical Observatory of Japan Mitaka-shi 181-8588 Japan Graduate School of Engineering Chiba University Chiba 263-8522 Japan

We demonstrate fast time-division color etectroholography using a multiple-graphics-processing-unit （GPU） cluster system with a spatial light modulator and a controller to switch the color of the reconstructing light. The controller comprises a universal serial bus module to drive the liquid crystal optical shutters. By using the controller, the computer-generated hologram （CGH） display node of the multiple-GPU cluster system synchronizes the display of the CGH with the color switching of the reconstructing light. Fast time-division color electroholography at 20 fps is realized for a three-dimensional object comprising 21,000 points per color when 13 GPUs are used in a multiple-GPU cluster system.

关键词： GPU RGB Fast time-division color electroholography using a multiple-graphics processing unit cluster system with a single spatial light modulator CGH

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太空发育鸡胚的前庭感受器细胞形态学研究

神经解剖学杂志 2002年第3期18卷 227-231页

作者：陈向东 Cesar D.Fermin Dale Martin hirotaka Hara Jun Hara 郑州大学第二附属医院耳鼻咽喉科郑州450003 DepartmentofPathologyandLaboratoryMedicine TulaneUniversity DepartmentofOtolaryngology YamaguchiUniversity

为了探讨太空微重力对鸡胚前庭感觉上皮细胞的形态发育的影响 ,选取在航天飞机 (STS-2 9)发育鸡胚和地面发育鸡胚各两只 ,利用计算机显微测量技术分别测量椭圆囊和球囊的毛细胞、支持细胞核的切面面积、周长、形状系数。太空发育鸡胚的... 详细信息

为了探讨太空微重力对鸡胚前庭感觉上皮细胞的形态发育的影响 ,选取在航天飞机 (STS-2 9)发育鸡胚和地面发育鸡胚各两只 ,利用计算机显微测量技术分别测量椭圆囊和球囊的毛细胞、支持细胞核的切面面积、周长、形状系数。太空发育鸡胚的球囊支持细胞核的切面面积、周长显著大于地面组 ,形状系数无差异 ;太空发育鸡胚的椭圆囊支持细胞核的切面面积、周长、形状系数以及椭圆囊和球囊毛细胞的切面面积、周长与地面发育鸡胚相比无明显差异。微重力可能对球囊支持细胞核的体积发育有影响 ,对椭圆囊和球囊的毛细胞以及椭圆囊支持细胞核的形态发育无影响。

关键词：前庭毛细胞前庭支持细胞核微重力太空发育鸡胚前庭感受器细胞形态学

Clinicopathological characteristics of clinical early gastric cancer in the upper-third stomach

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World Journal of Gastroenterology 2015年第45期21卷 12851-12856页

作者： Daisuke Ichikawa Shuhei Komatsu Toshiyuki Kosuga hirotaka Konishi Kazuma Okamoto Atsushi Shiozaki Hitoshi Fujiwara Eigo Otsuji Division of Digestive Surgery Department of Surgery Kyoto Prefectural University of Medicine

AIM: To elucidate the clinicopathological characteristics of clinically early gastric cancer in the upper-third stomach and to clarify treatment ***: A total of 683 patients with clinical early gastric cancer were enrolled in this retrospective study, 128 of whom had gastric cancer in the upper-third stomach(U group). All patients underwent a double contrast barium examination, endoscopy, and computed tomography(CT), and were diagnosed preoperatively based on the findings obtained. The clinicopathological features of these patients were compared with those of patients with gastric cancer in the middle- and lower-third stomach(ML group). We also compared clinicopathological factors between accurate-diagnosis and under-diagnosis groups in order to identify factors affecting the accuracy of a preoperative diagnosis of tumor ***: Patients in the U group were older(P = 0.029), had a higher ratio of males to females(P = 0.015), and had more histologically differentiated tumors(P = 0.007) than patients in the ML group. A clinical under-diagnosis occurred in 57 out of 683 patients(8.3%), and was more frequent in the U group than in the ML group(16.4% vs 6.3%, P < 0.0001). Therefore, the rates of lymph node metastasis and lymphatic invasion were slightly higher in the U group than in the ML group(P = 0.071 and 0.082, respectively). An under-diagnosis was more frequent in histologically undifferentiated tumors(P = 0.094) and in those larger than 4 cm(P = 0.024). The medianfollow-up period after surgery was 56 mo(range, 1-186 mo). Overall, survival and disease-specific survival rates were significantly lower in the U group than in the ML group(P = 0.016 and 0.020, respectively). However, limited operation-related cancer recurrence was not detected in the U group in the present ***: Clinical early gastric cancer in the upper-third stomach has distinguishable characteristics that increase the risk of a clinical under-diagnosis, especially i

关键词： Upper-third stomach Diagnosis Gastric cancer

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动态轮轴衡

中国检验检测 1985年第5期 36-38+65页

作者： hirotaka Yoshikawa 周祖濂

一、前言对当代公路结构和路面的设计技术有赖于考虑到车辆的轮轴重量和车辆的频率等有关的资料。轮轴的重量可能是一种重要的因素。使用公路秤台上的常规秤来测量所有类型车辆的一个轮轴的重量是很重要的。所以,能

关键词：测力传感器车辆轴重轴荷重积分器车轮结构轮轴

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日本,长野县,长野市,八岳某住宅

居业 2014年第4期 64-69页

作者： hirotaka Kidosaki 45g Photography Kidosaki Architects Studio

建筑师提供的项目信息。这座住宅坐落在八岳山脉山脚下倾斜山脊上的一块土地上，这里可以欣赏到鲜为人知的壮观景色。

关键词：住宅长野县日本项目信息建筑师景色

Nuclear corepressor 1 expression predicts response to first-line endocrine therapy for breast cancer patients on relapse

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Chinese Medical Journal 2009年第15期122卷 1764-1768页

作者： ZHANG Zhen-huan Hiroko Yamashita Tatsuya Toyama Yutaka Yamamoto Teru Kawasoe Mutsuko lbusuki Saori Tomita Hiroshi Sugiura Shunzo Kobayashi Yoshitaka Fujii hirotaka Iwase Department of Breast and Endocrine Surgery Faculty of Medical and Pharmaceutical Sciences Kumamoto University Honjo 1-1-1 Kumamoto 860-8556 Japan Department of Oncology and Immunology Nagoya City University Graduate School of Medical Sciences Kawasumi 1 Mizuho-ku Nagoya 467-8601 Japan

Background Estrogen receptor alpha （ER α） is the most important endocrine therapy responsiveness predictor for women with breast cancer. The accuracy of the prediction of the response to endocrine therapy was thought to be affected by involving the estrogen receptor coregulatory proteins and cross-talk between ER and other growth factor-signaling networks. Nuclear corepressor 1 （NCOR1） is one of the ER a transcription repressor. The objective of the study is to investigate the expression of NCOR1 at the protein level and pursue its predictive value for breast cancer endocrine therapy. Methods In the present study, the level of expression of NCOR1 protein has been assessed by immunohistochemistry in 104 cases of invasive carcinoma of the breast. Associations between NCOR1 protein expression and different clinicopathological factors and survival were sought. Results It was found that NCOR1 was expressed at significantly higher levels in responsive patients treated with endocrine therapy as first-line treatment on relapse. Responsive patients also had a significantly longer post-relapse survival and overall survival. No NCOR1 expression difference was found between patient by age, tumor size, lymph node status, different histological grade groups and human epidermal growth factor receptor 2 （HER2） status. Multivariate analysis showed that NCOR1 is an independent prognostic factor for over-all survival. Conclusions In breast cancer, NCOR1 protein expression level predicts response to endocrine therapy as first-line treatment for breast cancer patients on relapse and NCOR1 protein level assay may increase the accuracy in the endocrine treatment determination and, therefore, improving the patients survival.

关键词： breast cancer estrogen receptor nuclear corepressor 1 progesterone receptor prognosis

Three Dimentional Anemometer Using Thin Film Temperature Elements

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Three Dimentional Anemometer Using Thin Film Temperature Ele...

Natural history of major complications in hepatitis C virus-related cirrhosis evaluated by per-rectal portal scintigraphy

2019中国汽车工程学会年会

作者： Guo Xiaolin Takafumi Matsumoto Hirohito Matsui Yukikatsu Ozaki Yasutaka Kamiya Koji Kondo hirotaka Miyano SOKEN INC. DENSO CORPORATION

Two different types of three dimensional anemometers were proposed in order to analyse airflow in engine *** consists of multiple thin film temperature elements formed on a sphere *** measurement principles of each an... 详细信息

关键词： anemometer heat-fluid air cooling system

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World Journal of Gastroenterology 2005年第25期11卷 3882-3886页

作者： Etsushi Kawamura Daiki Habu Takehiro Hayashi Ai Oe Jin Kotani hirotaka Ishizu Kenji Torii Joji Kawabe Wakaba Fukushima Takashi Tanaka Shuhei Nishiguchi Susumu Shiomi Department of Nuclear Medicine Department of Hepatology Department of Public Health

AIM: To examine the correlation between the porto-systemic hypertension evaluated by portal shunt index (PSI) and life-threatening complications, including hepatocellular carcinoma (HCC), liver failure (Child-Pugh stage progression), and esophagogastric varices. METHODS: Two hundred and twelve consecutive subjects with HCV-related cirrhosis (LC-C) underwent per-rectal portal scintigraphy. They were allocated into three groups according to their PSI: group Ⅰ, PSI≤10%; group Ⅱ, 10%

关键词： Portal shunt index Porto-systemic shunting Per-rectal portal sdntigraphy Natural history Liver cirrhosis HCV Hepatocellular carcinoma Liver failure Varix