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Multiple carcinosarcomas of the esophagus with adenocarcinomatous components: A case report

World Journal of Gastroenterology 2020年第17期26卷 2111-2118页

作者： hiroshi Okamoto hiroshi Kikuchi hiroshi Naganuma Takashi Kamei Department of Gastroenterological Surgery Graduate School of MedicineTohoku UniversitySendai 980-8574Japan Department of Surgery South Miyagi Medical CenterMiyagi 989-1253Japan Department of Pathology Sendai City HospitalSendai 982-8502Japan

BACKGROUND Carcinosarcoma(spindle cell carcinoma) of the esophagus is an extremely rare event;the etiology and origins of this neoplasm have not yet been ***-mesenchymal transition(EMT) has been associated with invasion and metastasis, and may be related to the generation of a stem cell population within this *** SUMMARY We present the case of a 61-year-old male with nausea and fever. Upper gastrointestinal endoscopy revealed the presence of type 1 and 0-Ⅱc lesions located 35 cm from the incisors toward the esophago-gastric *** esophagectomy was performed. Macroscopic analysis revealed three polypoid lesions in the abdominal esophagus that accompanied the main lesion in the lower thoracic esophagus and 0-Ⅱc lesions that spread continuously with them. Histologically, the lesions included proliferating spindle cells. Adenocarcinomatous components were detected in a section near the foot, and squamous cell carcinoma was identified in the mucosa at the base of the *** patient was diagnosed with multiple carcinosarcomas, staged at pT1b(SM3),pN1(#110, #7), cM0, Stage Ⅱ(sarcomatous metastasis to the lymph nodes).Spindle cells did not express E-cadherin but were positive for EMT markers,including zinc finger E-box-binding homeobox 1, TWIST, and snail family transcriptional repressor 2. The patient has experienced no recurrence at 5 years and 2 mo after *** This report suggests that multiple sarcomatous tumors may be generated from primary squamous cell carcinoma via mechanisms related to EMT.

关键词： Esophagus Multiple carcinosarcomas Multiple spindle cell carcinomas Epithelial-mesenchymal transition Epithelial-mesenchymal transition markers Case report

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Novel function of the chemorepellent draxin as a regulator for hippocampal neurogenesis

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Neural Regeneration Research 2018年第5期13卷 799-800页

作者： hiroshi Tawarayama Department of Developmental Neurobiology Graduate School of Medical Sciences Kumamoto University Kumamoto Japan Department of Project Programs Institute of Development Aging and Cancer (IDAC) Tohoku University Sen dai Japan Department of Ecoiogy and Evolutionary Biology Graduate School of Life Sciences Tohoku University Sendai Japan

Hippocampal neurogenesis as a therapeutic target for neurological disorders：Mature granule cells are continuously differentiated from neural stem and progenitor cells and integrated into the preexisting neural system... 详细信息

关键词： MECHANISMS GUIDANCE DEATH

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Testing of Rice Stocks for Their Survival of Winter Cold

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Rice science 2018年第2期25卷 117-120页

作者： hiroshi IKEHASHI Kataseyama 3-10-6 Fujisawa 2510033 Japan

Rice cultivation is considered to be initiated by vegetative propagation of sprout from wild perennial stocks. To test whether any presently cultivated rice cultivar can survive the winter cold or not, rice stocks of several cultivars including indica and japonica types were placed in a shallow pool from October to April in 2015–2016 and 2016–2017. During the coldest period of the winter, the bases of the stocks were placed 5–6 cm below the surface of water, where temperatures ranged from 3 ℃ to 5 ℃, while the surface was frozen for two or three times and covered with snow for a day. Only one cultivar, Nipponbare, a japonica type, survived the winter cold and regenerated sprouts in the end of April or early May. A possibility to develop perennial cultivation of rice or perennial hybrid rice is discussed.

关键词： rice stock cold Nipponbare temperature winter

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Asphericalizing the Light Collection Mirror for the 200-Point Thomson Scattering Diagnostic Installed on the Large Helical Device

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Plasma Science and Technology 2011年第4期13卷 415-419页

作者： Kazumichi NARIHARA hiroshi HAYASHI National Institute for Fusion Science

Shown is a possibility to make the image of a laser beam over a distance of 2.5 m, formed by the spherical multi-segment mirror installed in LHD, twice sharper by suitably adjusting the inclination of each segment mirror, which is equivalent to making the mirror surface aspherical. This will further enhance the attractiveness of a mirror-based Thomson scattering system.

关键词： Thomson scattering LHD aspherical mirror

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Computer-generated holograms for 3D display(Invited Paper)

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Chinese Optics Letters 2009年第12期7卷 1079-1082页

作者： hiroshi Yoshikawa Takeshi Yamaguchi Department of Electronics and Computer Science Nihon University

We have been studying various types of computer-generated holograms for three-dimensional （3D） displays both for a real-time holographic video display and a hard copy, or a printed hologram. For the hard copy output, we have developed a direct fringe printer, which is achieved to print over 100 gigapixels computer-generated hologram with 0.44μm pitch. In this paper, we introduce our recent progresses on the rainbow hologram, the cylindrical holograms, and the disk hologram for 3D display.

关键词： Computer-generated holograms for 3D display Figure

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Lepton mass matrix from double covering of A_(4) modular flavor symmetry

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Chinese Physics C 2022年第12期46卷 162-171页

作者： hiroshi Okada Yuta Orikasa Asia Pacific Center for Theoretical Physics(APCTP)-Headquarters San 31 Hyoja-dongNam-guPohang 790-784Korea Department of Physics Pohang University of Science and TechnologyPohang 37673Republic of Korea Institute of Experimental and Applied Physics Czech Technical University in PragueHusova 240/511000 Prague 1Czech Republic

We study a double covering of modular A_(4)flavor *** this end,we construct lepton models for canonical and radiative seesaw *** irreducible doublet representations,heavier Majorana fermion masses are characterized by one free parameter that would differentiate from A_(4)***χsquare numerical analysis,we demonstrate that both scenarios produce some predictions in case of normal hierarchy reproducing neutrino oscillation ***,no solution satisfies the neutrino oscillation data in case of radiative seesaw of inverted hierarchy.

关键词： flavor physics neutrino and Lepton mass beyond the standard model

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Short-fetch high waves during the passage of 2019 Typhoon Faxai over Tokyo Bay

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Frontiers of Earth Science 2022年第1期16卷 206-219页

作者： hiroshi Takagi Atsuhei TAKAHASHI School of Environment and Society Tokyo Institute of TechnologyTokyo 152-8550Japan

The risk of wind waves in a bay is often overlooked,owing to the belief that peninsulas and islands will inhibit high ***,during the passage of a tropical cyclone,a semi-enclosed bay is exposed to twodirectional waves:one generated inside the bay and the other propagated from the outer *** Faxai in 2019 resulted in the worst coastal disaster in Tokyo Bay in the last few *** authors conducted a post-disaster survey immediately after this *** modeling was also performed to reveal the mechanisms of unusual high *** significant high-wave damage occurred on coasts facing the Pacific *** contrast,Fukuura-Yokohama,which faces Tokyo Bay,suffered overtopping waves that collapsed *** precisely reproduce multi-directional waves,the authors developed an extended parametric typhoon model,which was embedded in the JMA mesoscale meteorological model(JMA-MSM).The peak wave height was estimated to be 3.4 m off the coast of Fukuura,in which the contribution of the outer-sea waves was as low as 10%–20%.A fetchlimited wave developed over a short distance in the bay is considered the primary mechanism of the high *** maximum wave occurred on the left-hand side of the typhoon track in the bay,which appears to be contrary to the common understanding that it is safer within the semicircle of a storm than on the opposite *** Faxai was a small typhoon;however,if the radius was tripled,it is estimated that the wave height would exceed 3 m over the entire bay and surpass 4 m off the coasts of Yokohama and Chiba.

关键词： Typhoon Faxai Tokyo Bay high waves short fetch overtopping wave hindcasting parametric typhoon JMA-MSM storm surge

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Pediatric kidney transplantation during the COVID-19 pandemic

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World Journal of Clinical Cases 2022年第34期10卷 12494-12499页

作者： hiroshi Tamura Department of Pediatrics Kumamoto UniversityKumamoto 860-8556Japan

A waiting list for non-emergency transplant medical care was recommended in the first half of 2020 due to the coronavirus disease 2019(COVID-19)***,the number of kidney transplants temporarily ***,the waiting list for transplant medical care was lifted in the latter half of 2020 with the establishment of a polymerase chain reaction test system and the spread of infection *** basic stance is to recommend vaccination to posttransplant recipients,recipients,and donors who are scheduled to undergo transplantation,and their families,with the start of vaccine therapy in *** mortality rate of patients undergoing kidney transplants who had COVID-19 is slightly higher than healthy persons,and acute kidney injury was reported to lead to graft ***,pediatric cases of severe disease are rare and without *** transplantation medical care will be continuously provided by implementing infection prevention and treatments based on the latest evidence,promoting donated kidney transplantation,and hoping that pediatric patients with renal failure will grow up healthy,both physically and mentally,and become independent members of society,just like healthy children.

关键词： Kidney transplantation COVID-19 pandemic Children

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Comparison between experimental and analytical results for seesaw energy dissipation systems using fluid viscous dampers

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Earthquake Engineering and Engineering Vibration 2016年第1期15卷 79-90页

作者： Jae-Do Kang hiroshi Tagawa Hyogo Earthquake Engineering Research Center National Research Institute for Earth Science and Disaster Prevention Graduate School of Engineering Hiroshima University

This paper presents results of experimental and numerical investigations of a seesaw energy dissipation system （SEDS） using fluid viscous dampers （FVDs）. To confirm the characteristics of the FVDs used in the tests, harmonic dynamic loading tests were conducted in advance of the flee vibration tests and the shaking table tests. Shaking table tests were conducted to demonstrate the damping capacity of the SEDS under random excitations such as seismic waves, and the results showed SEDSs have sufficient damping capacity for reducing the seismic response of flames. Free vibration tests were conducted to confirm the reliability of simplified analysis. Time history response analyses were also conducted and the results are in close agreement with shaking table test results.

关键词： seesaw energy dissipation system experimental verification shaking table test simplified analysis dynamiccharacteristic

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日本地震预警系统研究综述

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世界地震工程 2024年第3期40卷 72-82页

作者：宝音图王鹏翔徐茂臣川濑博内蒙古大学交通学院内蒙古呼和浩特010020 京都大学防灾研究所京都611-0011

为深入了解日本地震预警系统在防震减灾中的有效应用,本文首先,介绍了日本地震预警系统的研究现状,包括铁路地震预警系统、陆域和海域地震预警系统以及长周期地震预警系统;其次,阐述了预警发布标准、发布方式和发布后的避险措施,总结了... 详细信息

为深入了解日本地震预警系统在防震减灾中的有效应用,本文首先,介绍了日本地震预警系统的研究现状,包括铁路地震预警系统、陆域和海域地震预警系统以及长周期地震预警系统;其次,阐述了预警发布标准、发布方式和发布后的避险措施,总结了地震预警的特点、局限性和注意事项,讨论了我国在地震预警系统建设时遇到的问题。通过对日本地震预警系统的全面介绍和深入分析,有利于了解该系统的运行机制、应用效果以及面临的挑战,为我国地震预警事业的发展提供重要参考。

关键词：防震减灾日本地震预警地震预警系统长周期地震动预警发布标准

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