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Manipulation of Micro Solid Particles and Induced Flows in Water by Laser Irradiation

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Journal of Thermal Science 2007年第2期16卷 176-180页

作者： Masahiro OTA hiroshi OKANO Makoto YOSHIDA Division of Mechanical Engineering Tokyo Metropolitan University1Minami-osawaHachi-ojiTokyo 192-0397Japan

Q-switch for pulsing laser beam and Galvano scanner for rapid scanning laser beam were adapted to manipulate micro solid particles in a water droplet. The trapping of fine particles at micron-sized diameters by a YAG laser system, induced flows, and the induced motion of the particles by laser beam irradiations are discussed. Particle rotations are observed by using anisotropic micro objects, and moreover the rotational rate with clockwise direction is 22 r/min. The fragments of a cover glass were mixed in a water droplet, and their size and shape are uneven. The rotation of that non-spheres without scanning by the Galvano scanner is also observed in water.

关键词： Laser trapping non-sphere particle optical radiation pressure laser scanning laser drive rotation

An Electronic Approach to Materials Design

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Journal of Materials Science & Technology 2003年第z1期19卷 73-76页

作者： Masahiko MORINAGA Yoshinori MURATA hiroshi YUKAWA Department of Materials Science and Engineering Graduate School of Engineering Nagoya UniversityNagoya 464-8603 Japan Department of Materials Science and Engineering Graduate School of Engineering Nagoya UniversityNagoya 464-8603 Japan Department of Materials Science and Engineering Graduate School of Engineering Nagoya UniversityNagoya 464-8603 Japan

A molecular orbital approach to materials design has recently made great progress. This approach is based onthe electronic structure calculations by the DV-Xα cluster method. In this paper recent progress in this approachis reviewed. In particular, it is stressed that New PHACOMP approach is useful for predicting the formation oftopologically close-packed (TCP) phases (e.g., σ phase andμ phase ) in nickel based superalloys. Compared to thecurrent PHACOMP, New PHACOMP provides a better tool for designing those alloys which are free from such TCPprecipitates at service temperatures. In addition, the d-electrons concept is shown for alloy design and development.

关键词： High temperature materials, Ni based superalloys, Alloy design, Molecular orbital method

A multi-charged particle model with local U(1)_(μ-τ) to explain muon g-2,flavor physics,and possible collider signature

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Chinese Physics C 2022年第4期46卷 57-69页

作者： Nilanjana Kumar Takaaki Nomura hiroshi Okada Department of Physics and Astrophysics University of DelhiDelhi 110007India School of Physics KIASSeoul 02455Korea Asia Pacific Center for Theoretical Physics(APCTP)-Headquarters San 31 Hyoja-dongNam-guPohang 790-784Korea Department of Physics Pohang University of Science and TechnologyPohang 37673Korea

We consider a model with multi-charged particles,including vector-like fermions,and a charged scalar under a local U(1)_(μ−τ) *** search for an allowed parameter region explaining muon anomalous magnetic moment(muon g−2)and b→sℓ^(+)ℓ^(−) anomalies,satisfying constraints from the lepton flavor violations,Z boson decays,meson anti-meson mixing,and collider *** numerical analysis,we explore the typical size of the muon g−2 and Wilson coefficients to explain the b→sℓ^(+)ℓ^(−) anomalies in our model when all other experimental constraints are ***,we discuss the collider physics of the multicharged vectorlike fermions,considering a number of benchmark points in the allowed parameter space.

关键词： new gauge boson new gauge symmetry muon anomalous magnetic moment B meson decay anomalies collider physics

Reflection Asymmetric Relativistic Mean Field Approach and Its Application to the Octupole Deformed Nucleus ^226Ra

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Chinese Physics Letters 2007年第7期24卷 1865-1868页

作者：耿立升孟杰 Toki hiroshi School of Physics Peking University Belting 100871 Institute of Theoretical Physics Chinese Academy of Sciences Beijing 100080 Center of Theoretical Nuclear Physics National Laboratory of Heavy Ion Accelerator Lanzhou 730000 Research Center for Nuclear Physics (RCNP) Osaka University Ibaraki 567-0047 Japan

A reflection asymmetric relativistic mean field （RAS-RMF） approach is developed by expanding the equations of motion for both the nucleons and the mesons on the eigenfunctions of the two-centre harmonic-oscillator potential. The efficiency and reliability of the RAS-RMF approach are demonstrated in its application to the well-known octupole deformed nucleus 226Ra and the available data, including the binding energy and the deformation parameters, are well reproduced.

关键词： Asymmetric Application Deformed

Typhoon parameter sensitivity of storm surge in the semi-enclosed Tokyo Bay

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Frontiers of Earth Science 2020年第3期14卷 553-567页

作者： Md.Rezuanul Islam hiroshi Takagi School of Environment and Society Tokyo Institute of TechnologyTokyo152-8550Japan

In this study,a storm surge model of the semi-enclosed Tokyo Bay was constructed to investigate its hydrodynamic response to major typhoon parameters,such as the point of landfall,approach angle,forward speed,size,and *** typhoon simulation was validated for Typhoon Lan in 2017,and 31 hypothetical storm surge scenarios were generated to establish the sensitivity of peak surge height to the variation in typhoon *** maximum storm surge height in the upper bay adjacent to the Tokyo Metropolitan Area was found to be highly sensitive to the forward speed and size of the passing ***,the importance of these parameters in disaster risk reduction has been largely overlooked by researchers and disaster *** was also determined that of the many hypothetical typhoon tracks evaluated,the slow passage of a large and intense typhoon transiting parallel to the longitudinal axis of Tokyo Bay,making landfall 25 km southwest,is most likely to cause a hazardous storm surge scenario in the upper-bay *** results of this study are expected to be useful to disaster managers for advanced preparation against destructive storm surges.

关键词： storm surge risk semi-enclosed bay typhoon parameters parametric study Typhoon Lan

Clarithromycin Attenuates the Bronchial Epithelial Damage Induced by <i>Mycoplasma pneumoniae</i>Infection

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Advances in Microbiology 2014年第11期4卷 697-703页

作者： hiroshi Tanaka Hisato Sadakata Tae Nagami Shun Miyazaki Tsutomu tomita Shuhei Shirata Takehiro Yamagishi NPO Sapporo Cough Asthma and Allergy Center Sapporo Japan Taishotoyama Pharmaceutical Co. Ltd. Tokyo Japan TIMELAPSE VISION Inc. Saitama Japan

To analyze the bronchial epithelial cell damage induced by Mycoplasma pneumonia and the therapeutic effects of clarithromycin, we observed bronchial tissue damage by using a mouse model and performing immunostaining and scanning electron microscopy. The immunostaining study showed that M. pneumoniae-labeled fluorescence was found on the mucosal epithelium of mice, 6 days after inoculation. Clarithromycin treatment reduced the fluorescence. In this study, we demonstrated that the morphological alterations of bronchial mucosa, including the shortening and loss of ciliavisualized by scanning electron microscopy, and the inflammatory cell migration in the submucosal tissue visualized by differential interference contrast microscopy, were induced by mycoplasmal infection. We also showed that clarithromycin treatment, when administered from the first day of inoculation, attenuated both the bronchial epithelial damage and inflammatory cell migration in the submucosal tissue. These results suggest that the therapeutic effects of clarithromycin against mycoplasmal infection, may be due to its antibacterial and anti-inflammatory activities.

关键词： Mycoplasma pneumoniae Epithelial Cell Damage Clarithromycin Murine Model

Requirements for implementation of artificial intelligence in the practice of gastrointestinal pathology

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World Journal of Gastroenterology 2021年第21期27卷 2818-2833页

作者： hiroshi Yoshida Tomoharu Kiyuna Department of Diagnostic Pathology National Cancer Center HospitalTokyo 104-0045Japan Digital Healthcare Business Development Office NEC CorporationTokyo 108-8556Japan

Tremendous advances in artificial intelligence(AI)in medical image analysis have been achieved in recent *** integration of AI is expected to cause a revolution in various areas of medicine,including gastrointestinal(GI)***,deep learning algorithms have shown promising benefits in areas of diagnostic histopathology,such as tumor identification,classification,prognosis prediction,and biomarker/genetic alteration *** AI cannot substitute pathologists,carefully constructed AI applications may increase workforce productivity and diagnostic accuracy in pathology *** of these promising advances,unlike the areas of radiology or cardiology imaging,no histopathology-based AI application has been approved by a regulatory authority or for public ***,implying that there are still some obstacles to be overcome before AI applications can be safely and effectively implemented in real-life pathology *** challenges have been identified at different stages of the development process,such as needs identification,data curation,model development,validation,regulation,modification of daily workflow,and cost-effectiveness *** aim of this review is to present challenges in the process of AI development,validation,and regulation that should be overcome for its implementation in real-life GI pathology practice.

关键词： Artificial intelligence Deep learning Digital image analysis Digital pathology Clinical implementation Gastrointestinal cancer

Effects of Freestream Turbulence on Bypass Transition of Separated Boundary Layer on Low-Pressure Turbine Airfoils

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Journal of Thermal Science 2012年第3期21卷 230-235页

作者： Hideo Taniguchi hiroshi Sakai Ken-ichi Funazaki Department of Mechanical Systems Engineering Faculty of EngineeringIwate University

This paper presents experimental studies on bypass transition of separated boundary layer on low-pressure turbine airfoils,focusing on the effects of freestream turbulence on the transition ***-wire probe measurements are performed on the suction side of an airfoil in the low-pressure linear turbine cascade at several Reynolds number *** turbulence is enhanced by use of turbulence grid located upstream of the *** results of this experimental study show that the location of boundary layer separation does not strongly de-pend on the freestream turbulence ***,as the freestream turbulence level increases,the size of separa-tion bubble becomes small and the location of turbulent transition moves *** size of separation bubble becomes small as the Reynolds number *** low freestream turbulence intensity,the velocity fluctuation due to Kelvin-Helmholtz instability is observed clearly in the shear layer of the separation *** high frees-tream turbulence intensity,the streak structures appear upstream of the separation location,indicating bypass transition of attached boundary layer occurs at high Reynolds number.

关键词： Aeroengine Low-Pressure Turbine Bypass Transition Separation Bubble

Synergistic effects of anti-angiogenesis and immune checkpoint blockade-a new era of systemic chemotherapy for hepatocellular carcinoma

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Hepatobiliary & Pancreatic Diseases International 2021年第5期20卷 493-495页

作者： Yuji Eso hiroshi Seno Department of Gastroenterology and Hepatology Graduate School of MedicineKyoto UniversityKyotoJapan

Tumor growth requires oxygen and nutrient supplementation through angiogenesis from preexisting vascular beds. Hepatocellular carcinoma(HCC) is a hyper-vascularized tumor with a predominant arterial blood flow. Therefore, targeting angiogenesis is essential for treating HCC. Currently approved molecular-targeted agents(MTAs) for HCC affect angiogenic pathways.

关键词： angiogenesis arterial chemotherapy