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Fate and Movement of Dioxins in the Lake Biwa Basin in Japan

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Fate and Movement of Dioxins in the Lake Biwa Basin in Japan

持久性有机污染物论坛2008暨第三届持久性有机污染物全国学术研讨会

作者： Yoshihisa Shimizu Keisuke Sato hiroshi murata Masafumi Nakamura Huang Chun-Ching Research Center for Environmental Quality Management Kyoto UniversityOtsu 520-0811Japan Hiyoshi Corporation Omihachiman 523-8555Japan

*** In Japan,the dioxins had been unintentionally produced as the byproducts of Chlorinated Organic Pesticides(COPs)(e.g,PCP and CNP)since 1960s to 1980s,and sprayed on the paddy *** major source of dioxins in Japan i...

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荧光素酶报告基因法测定飞灰中二噁英类物质

环境污染与防治 2016年第9期38卷 19-24页

作者：籍龙杰陆胜勇杜颖哲陈彤李晓东严建华黄俊卿 Masafumi Nakamura hiroshi murata 浙江大学能源清洁利用国家重点实验室热能工程研究所浙江杭州310027 株式会社日吉日本近江八幡市523-0806

荧光素酶报告基因法(CALUX)相比高分辨气相色谱/质谱法(HRGC/HRMS)测定二噁英浓度时,具有分析周期短、检测成本低、灵敏度高(皮克水平)、能反映样品的毒性总量且可进行高通量检测等优点。实际应用时,可先用CALUX对样品作初步筛选检测,... 详细信息

荧光素酶报告基因法(CALUX)相比高分辨气相色谱/质谱法(HRGC/HRMS)测定二噁英浓度时,具有分析周期短、检测成本低、灵敏度高(皮克水平)、能反映样品的毒性总量且可进行高通量检测等优点。实际应用时,可先用CALUX对样品作初步筛选检测,再将筛选出的阳性样品用化学分析法作进一步定性定量检测。通过对42个垃圾焚烧飞灰样品同时进行HRGC/HRMS和CALUX分析,得到两者的换算系数,从而可以利用快速检测的结果和换算系数来推算HRGC/HRMS的结果。实验表明,CALUX结果与HRGC/HRMS结果具有很好的线性相关性(R=0.96),换算系数为0.332。该换算系数与日本得到的结果不同,表明中国飞灰性质有别于日本飞灰。而且,不同环境介质之间换算系数也不一致。为增加该方法在中国的适用性,必须通过实验方法找出符合中国样品的换算系数。

关键词：二噁英荧光素酶报告基因法高分辨气相色谱/质谱法换算系数

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化学泵浦的碘激光器

中国激光 1983年第Z1期 589-589页

作者： Kazuhiko Serizawa Akira Otsuka hiroshi murata Taro Uchiyama Tomoo Fujioka 日本庆应大学电工系日本庆应大学电工系日本庆应大学电工系日本庆应大学电工系日本庆应大学电工系

本文给出了使用小尺寸真空泵的在低流速（2米/秒）下运转的横流化学泵浦碘激光器的性能。由化学发生器射出的气流经一个干冰乙醇吸附器,从而除去作为受激体的有效猝灭剂的水蒸气。激光器部分由一个70×2cm的管道组成,1m长的腔安装在离I... 详细信息

本文给出了使用小尺寸真空泵的在低流速（2米/秒）下运转的横流化学泵浦碘激光器的性能。由化学发生器射出的气流经一个干冰乙醇吸附器,从而除去作为受激体的有效猝灭剂的水蒸气。激光器部分由一个70×2cm的管道组成,1m长的腔安装在离I2注入点大约0.8cm的下游处,共振腔由两块反射镜组成:一块曲率半径为5米的全反射镜,另一块部分透过（T=1.5％）的平面镜。喉高为0.6cm的喷嘴放置在腔轴处,以便使分子碘和氧有效地混合。在90％（重量）H2O2,为1.1升和25％（重量）NaOH为0.5升时,采用大于40％的

关键词：碘激光器吸附器气体净化设备碘分子

组织调整材料的操作时间及固化时间的测量方法

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首都医科大学学报 2005年第4期26卷 505-508页

作者：赵晶洪光李英爱村田比吕司滨田泰三金辰中日友好医院口腔科广岛大学大学院医齿药学综合研究科齿科补缀学研究室德山齿科材料有限公司

目的利用移位式流变仪(Displacementrheometer),开发适当的测量组织调整材料的操作时间和固化时间的方法。方法使用5种组织调整材料。每个材料在23℃和37℃条件下各测量3次。在23℃下发生最初弹性回复的时间定义为操作时间,在37℃下弹... 详细信息

目的利用移位式流变仪(Displacementrheometer),开发适当的测量组织调整材料的操作时间和固化时间的方法。方法使用5种组织调整材料。每个材料在23℃和37℃条件下各测量3次。在23℃下发生最初弹性回复的时间定义为操作时间,在37℃下弹性复原率表现为稳定数据的时间定义为固化时间。结果各个组织调整材料的操作时间和固化时间有显著性差异,显示出不同的固化行为。5种组织调整材料中SR的操作时间最短,为(2.7±0.2)min,VG的操作时间最长,为(15.7±0.5)min。VG的固化时间最长〔(25.0±0.8)min〕,SR的固化时间最短〔(7.7±1.9)min〕。结论移位式流变仪方法可以用于测量组织调整材料的操作时间和固化时间,并对分析组织调整材料的固化过程有重大意义。

关键词：组织调整材料操作时间固化时间移位式流变仪

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Endoscopic identification of Peyer's patches of the terminal ileum in a patient with Crohn's disease

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World Journal of Gastroenterology 2004年第18期10卷 2767-2768页

作者： hiroshi Ishimoto Hajime Isomoto Saburo Shikuwa Chun Yang Wen Takashi Suematu Masahiro Ito Ikuo murata Hiromi Ishibashi Shigeru Kohno DepartmentofInternalMedicine NationalNagasakiMediealCenter2-1001KubaraOmuraNagasaki856-8562Japan GastrointestinalUnit.MassachusettsGenerulHospital DepartmentofMedicineHarvardMedicalSchoolJackson70655FruitStreetBostonMa02114USA DepartmentofMolecularPalhology AtomicBombDiseaseInstituteNagasakiUniversitySchoolofMedicine1-7-1SakarnotoNagasnki852-8501Japan ContralElectroscopeLaboratory NagasakiUniversitySchoolofMedicineNagasaki852-8501Japan DepartmentofPathology NationalNagasakiMedicalCenterj2-1001KubaraOmuraNagasaki856-8562Japan

We presented a 20-year-old patient with Crohn's disease (CD).Colonoscopy revealed longitudinal ulceration in the terminal ileum and rectal aphtoid *** treatment with mesalamine and total parenteral nutrition,repeat colonoscopy revealed a granular elevated area in the terminal ileum,which appeared as an irregular dome-like elevation with irregularly arranged villi on magnifying *** specimens taken from the region showed microgranulomas and lymphoid hyperplasia,Scanning electron microscopy revealed the presence of M cells,confirming that the area corresponded to Peyer's ***'s patches by magnifying endoscopy and electron microscopy may provide insights into the pathogenesis of CD.

关键词： Adult Biopsy Crohn Disease Endoscopes, Gastrointestinal Humans Ileum Intestinal Mucosa Male Microscopy, Electron, Scanning Peyer's Patches

Usefulness of the clip-flap method of endoscopic submucosal dissection: A randomized controlled trial

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World Journal of Gastroenterology 2018年第35期24卷 4077-4085页

作者： Hiromitsu Ban Mitsushige Sugimoto Taketo Otsuka Masaki murata Toshiro Nakata hiroshi Hasegawa Osamu Inatomi Shigeki Bamba Akira Andoh Division of Digestive Endoscopy Shiga University of Medical Science Hospital Department of Gastroenterology Shiga University of Medical Science Hospital Division of Clinical Nutrition Shiga University of Medical Science Hospital

AIM To prospectively investigate the efficacy and safety of clipflap assisted endoscopic submucosal dissection(ESD) for gastric *** From May 2015 to October 2016, we enrolled 104 patients with gastric cancer or adenoma scheduled for ESD at Shiga University of Medical Science Hospital. We randomized patients into two subgroups using the minimization method based on location of the tumor(upper, middle or lower third of the stomach), tumor size( 20 mm) and ulcer status: ESD using an endoclip(the clip-flap group) and ESD without an endoclip(the conventional group). Therapeutic efficacy(procedure time) and safety(complication: Gastrointestinal bleeding and perforation) were assessed. RESULTS En bloc resection was performed in all patients. Four patients had delayed bleeding(3.8%) and two had perforation(1.9%). No significant differences in en bloc resection rate(conventional group: 100%, clip flap group: 100%), curative endoscopic resection rate(conventional group: 90.9%, clip flap group: 89.8%, P = 0.85), procedure time(conventional group: 70.8 ± 46.2 min, clip flap group: 74.7 ± 53.3 min, P = 0.69), area of resected specimen(conventional group: 884.6 ± 792.1 mm^2, clip flap group: 1006.4 ± 1004.8 mm^2, P = 0.49), delayed bleeding rate(conventional group: 5.5%, clip flap group: 2.0%, P = 0.49), or perforation rate(conventional group: 1.8%, clip flap group: 2.0%, P = 0.93) were found between the two groups. Lessexperienced endoscopists did not show any differences in procedure time between the two *** For patients with early-stage gastric tumors, the clipflap method has no advantage in efficacy or safety compared with the conventional method.

关键词： Gastric cancer Clip flap method Endoscopic submucosal dissection Procedure time Complication Randomized clinical trial

Endovascular treatment of post-laparoscopic pancreatectomy splenic arteriovenous fistula with splenic vein aneurysm

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World Journal of Gastroenterology 2015年第25期21卷 7907-7910页

作者： Tatsuo Ueda Satoru murata Akira Yamamoto Jin Tamai Yuko Kobayashi Chiaki Hiranuma hiroshi Yoshida Shin-ichiro Kumita Department of Radiology Nippon Medical School Hospital Department of Radiology Nippon Medical School Tama Nagayama Hospital Department of Surgery Nippon Medical School Tama Nagayama Hospital

Splenic arteriovenous fistulas(SAVFs) with splenic vein aneurysms are extremely rare entities. There have been no prior reports of SAVFs developing after laparoscopic pancreatectomy. Here, we report the first case. A 40-year-old man underwent a laparoscopic, spleen-preserving, distal pancreatectomy for an endocrine neoplasm of the pancreatic tail. Three months after surgery, a computed tomography(CT) scan demonstrated an SAVF with a dilated splenic vein. The SAVF, together with the splenic vein aneurysm, was successfully treated using percutaneous transarterial coil embolization of the splenic artery, including the SAVF and drainage vein. After the endovascular treatment, the patient's recovery was uneventful. He was discharged on postoperative day 6 and continues to be well 3 mo after discharge. An abdominal CT scan performed at his 3-mo follow-up demonstrated complete thrombosis of the splenic vein aneurysm, which had decreased to a 40 mm diameter. This is the first reported case of SAVF following a laparoscopic pancreatectomy and demonstrates the usefulness of endovascular treatment for this type of complication.

关键词： Splenic arteriovenous fistula Splenic veinaneurysm Laparoscopic pancreatectomy Percutaneoustransarterial embolization Endovascular treatment

Geochemistry of groundwater in and around the MozumiSukenobu fault, northern central Japan

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Chinese Science Bulletin 1999年第S2期44卷 261-262页

作者： hiroshi Satake Masanobu murata Haruna Hayashi Department of Environmental Chemistry and Biology Toyama University Japan

IN the northern central part of Honshu Island, Japan, there is an Atostsugawa Active Fault system that isone of the most active faults in Japan. The Mozumi-Sukenobu fault is one of the Atotsugawa Active Faultsystems and is an ENE-WSW running right lateral strike slip fault. In February 1997, a fault survey tunnel was excavated across the Mozumi-Sukenobu fault from the Nagato tunnel excavated in the *** samples were collected along the Nagato and fault survey tunnels in and around the MozumiSukenobu fault and their chemical compositions, oxygen and hydrogen isotope ratios and tritium concentrations were measured. It is clearly observed that major chemical compositions of groundwater samples collected along theNagato tunnel are Ca and HCO3 ions. These sampling points are more than 500 m distant from the Mozumi-Sukenobu fault. This Ca-HCO3 type chemical composition is common in shallow groundwater. On thecontrary, groundwater samples in and adjacent to the Mozumi-Sukenobu fault have Ne-HCO3 type chemi-

关键词： geochemistry groundwater northern central Japan.

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Functional expression of a proliferation-related ligand in hepatocellular carcinoma and its implications for neovascularization

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World Journal of Gastroenterology 2005年第30期11卷 4650-4654页

作者： hiroshi Okano Katsuya Shiraki Yutaka Yamanaka Hidekazu Inoue Tomoyuki Kawakita Yukiko Saitou Yumi Yamaguchi Naoyuki Enokimura Keiichi Ito Norihiko Yamamoto Kazushi Sugimoto Kazumoto murata Takeshi Nakano First Department of Internal Medicine

AIM： To detect the expression of a proliferation-related ligand on human hepatocellular carcinoma （HCC） cell lines （SK-Hepl, HLE and HepG2） and in culture medium. METHODS： APRIL expression was analyzed by Western blotting in HCC cell lines. Effects of APRIL to cell count and angiogenesis were analyzed, too. RESULTS： Recombinant human APRIL （rhAPRIL） increased cell viability of HepG2 cells and, in HUVEC, rhAPRIL provided slight tolerance to cell death from serum starvation. Soluble APRIL （sAPRIL） from HLE cells increased after serum starvation, but did not change in SK-Hepl or HepG2 cells. These cells showed down-regulation of VEGF after incubation with anti-APRIL antibody. Furthermore, culture medium from the HCC cells treated with anti-APRIL antibody treatment inhibited tube formation of HUVECs. CONCLUSION： Functional expression of APRIL might contribute to neovascularization via an upregulation of VEGF in HCC.

关键词： A proliferation-inducing ligand HCC VEGF Cell proliferation Neovascularization