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Laparoscopic retroperitoneal lymph node dissection versus open retroperitoneal lymph node dissection for testicular cancer:A comparison of clinical and perioperative outcomes

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Asian Journal of Urology 2022年第2期9卷 119-124页

作者： Toshihide Shishido Takatsugu Okegawa Kenjiro Hayashi Kazuki Masuda Satoru Taguchi Yu Nakamura Mitsuhiro Tambo hiroshi fukuhara Department of Urology Hachioji Medical CenterTokyo Medical University1163TatemachiHachiojiTokyoJapan Department of Urology Kyorin University School of Medicine6-20-2 ShinkawaMitakaTokyoJap

Objective:This study was performed to evaluate the clinical and perioperative outcomes of laparoscopic retroperitoneal lymph node dissection(L-RPLND)and open retroperitoneal lymph node dissection(O-RPLND)performed by one surgeon at a single ***:We evaluated 30 patients with stage IIA germ cell tumors who underwent retroperitoneal lymph node dissection(15 underwent L-RPLND and 15 underwent O-RPLND)at our institution between April 1,2010 and March 31,*** clinical parameters were compared between patients who underwent L-RPLND using the retroperitoneal approach and those who underwent O-RPLND using the transperitoneal *** were no significant differences in the background characteristics of the two groups except for the median follow-up duration(46 months for L-RPLND and 71 months for O-RPLND,p=0.02).Results:L-RPLND was associated with a shorter mean operative time(mean 222 min for L-RPLND vs.453 min for O-RPLND,p<0.001).There was significantly less blood loss during surgery in the L-RPLND group compared to the O-RPLND group(mean 165 mL for L-RPLND vs.403 mL for O-RPLND,p<0.001).Parameters related to postoperative recovery were significantly better for the L-RPLND group than for the O-RPLND *** were no differences in the histopathological characteristics between the two *** patients in either group exhibited disease ***:Patients who underwent L-RPLND had more rapid recovery,and shorter hospital stay compared to those who underwent O-RPLND;complications were comparable between the two groups.L-RPLND is an efficient procedure with the benefits of minimally invasive surgery.

关键词： Laparoscopic surgery Retroperitoneal lymph node dissection Testicular tumor

脆壁克鲁维酵母蛋白二硫化物异构酶KfPDI的结构分析

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高技术通讯 1999年第8期9卷 39-43页

作者：赵翔包卫国霍克克李育阳 fukuharaH 复旦大学遗传学研究所基因工程国家重点实验室上海200433

利用ＤＮＡ限制性内切酶图谱分析将一个带有脆壁克鲁维酵母（Ｋｌｕｙｖｅｒｏｍｙｃｅｓｆｒａｇｉｌｉｓ）蛋白二硫化物异构酶基因（ＫｆＰＤＩ）的１０ｋｂ初始克隆缩短为４ｋｂ的亚克隆，并测定了该基因的ＤＮＡ全序列。经... 详细信息

利用ＤＮＡ限制性内切酶图谱分析将一个带有脆壁克鲁维酵母（Ｋｌｕｙｖｅｒｏｍｙｃｅｓｆｒａｇｉｌｉｓ）蛋白二硫化物异构酶基因（ＫｆＰＤＩ）的１０ｋｂ初始克隆缩短为４ｋｂ的亚克隆，并测定了该基因的ＤＮＡ全序列。经分析发现：（１）该基因编码产物由５２０个氨基酸残基组成。（２）它与乳酸克鲁维酵母（Ｋ．ｌａｃｔｉｓ）蛋白二硫化物异构酶在氨基酸序列上的同源性为７８。（３）它与其他物种的ＰＤＩ基因在核苷酸和蛋白质水平上的同源性较弱，

关键词：脆壁克鲁维酵母 PDI KfPDI 序列分析

One-Dimensional Analysis of Supersonic Two-Stage HVOF Process

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Journal of Thermal Science 2009年第4期18卷 332-337页

作者： hiroshi KATANODA Junichi HAGI Minoru fukuhara Dept.Mechanical Engineering Kagoshima University

The one-dimensional calculation of the gas/particle flows of a supersonic two-stage high-velocity oxy-fuel(HVOF) thermal spray process was performed. The internal gas flow was solved by numerically integrating theequations of the quasi-one-dimensional flow including the effects of pipe friction and heat transfer. As for the supersonicjet flow, semi-empirical equations were used to obtain the gas velocity and temperature along the centerline. The velocity and temperature of the particle were obtained by an one-way coupling method. The material ofthe spray particle selected in this study is ultra high molecular weight polyethylene (UHMWPE). The temperaturedistributions in the spherical UHMWPE particles of 50 and 150 m accelerated and heated by the supersonic gasflow was clarified.

关键词： Compressible Flow Supersonic Flow Two-Stage HVOF Thermal Spray One-Dimensional Analysis UHMWPE

Cooling Curve's Effect on Hardening Behavior of Steel

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材料热处理学报 2004年第5期25卷 462-464页

作者： Kazuto fukuhara Shigeru Asada Yoshihiro Tomita Syusaku Maeda Nippon Grease Co. Ltd. Osaka JapanNippon Grease Co. Ltd. Osaka JapanNippon Grease Co. Ltd. Osaka JapanNippon Grease Co. Ltd. Osaka Japan

Quenching Oils are comprised mostly of mineral oil as major component, but mineral oil alone result in lower cooling performance. Therefore, various additives are formulated as required for each particular case. Cooling curves of mineral oil as determined by JIS method can be divided into three stages, vapor film stage, boiling stage and convection stage. And there are many types of additives used for quenching oil, one effective to shorten vapor film stage and another to shift boiling stage toward lower temperature side. As rapid quenching required temperature range for particular steel varies pending on its shape of CCT curve"1, it is possible to provide higher quench hardening performance using quenching oil formulated of adequate additives.

关键词：淬火油冷却效果硬化性能钢

Catalytic liquid phase oxidation of 1,4-dioxane over a Pt/CeO_(2)-ZrO_(2)-Bi_(2)O_(3)/SBA-16 catalyst

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Journal of Advanced Ceramics 2015年第1期4卷 71-75页

作者： Pil-Gyu CHOI Takanobu OHNO Nashito fukuhara Toshiyuki MASUI Nobuhito IMANAKA Department of Applied Chemistry Faculty of EngineeringOsaka University2-1 YamadaokaSuitaOsaka 565-0871Japan

A Pt/CeO_(2)-ZrO_(2)-Bi_(2)O_(3)/SBA-16(Santa Barbara Amorphous No.16)catalyst was prepared by hydrothermal and wet impregnation methods for catalytic purification of 1,4-dioxane in ***-16 has a number of mesopores and the average size of the pores is 9.4 *** the present catalyst,platinum and CeO_(2)-ZrO_(2)-Bi_(2)O_(3)were successfully dispersed in the pores of the SBA-16 support,and the temperature dependence of the liquid phase oxidation of 1,4-dioxane was *** oxidation reaction proceeded effectively in the air atmosphere in the temperature range of 40-80℃.

关键词： composite materials oxidation porous materials 1,4-dioxane catalyst

Characterization of a Microhollow Cathode Discharge Plasma in Helium or Air with Water Vapor

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Plasma Science and Technology 2013年第2期15卷 129-132页

作者： D. fukuhara S. NAMBA K. KOZUE T. YAMASAKI K. TAKIYAMA Graduate school of Engineering Hiroshima University1-4-1 KagamiyamaHigashi-HiroshimaHiroshima 739-8527Japan

Microhollow cathode discharge （MHCD） plasmas were generated in gas mixtures containing water vapor at pressures of up to 100 kPa of He or 20 kPa of air. The cathode diameter was 1.0 mm with a length of 2.0 ram. The electricM characteristics showed an abnormal glow mode. Spectroscopic measurements were carried out to examine the plasma and radicals. An analysis of the spectral profile of Ha at 656.3 nm enabled a derivation of the electron densities, namely 2× 1014 cm-3 （at 10 kPa） and 6× 1014 cm-3 （at 4 kPa） for the helium and air atmospheres, respectively, in the negative glow region. By comparing the observed OH radical spectra with those calculated by the simulation code L[FBASE, the gas temperature was deduced to be 900 K for 4 kPa of He at a discharge current of 50 mA.

关键词： microhollow cathode discharge atmospheric pressure plasma plasma spec-troscopy

Physical multimorbidity patterns and depressive symptoms:a nationwide cross-sectional study in Japan

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Family Medicine and Community Health 2020年第1期8卷 14-19页

作者： Takuya Aoki Yosuke Yamamoto Sayaka Shimizu Shunichi fukuhara Department of Healthcare Epidemiology Kyoto UniversityKyotoJapan Institute for Health Outcomes and Process Evaluation Research(iHope International) KyotoJapan Department of General Medicine Fukushima Medical UniversityFukushimaJapan Center for Innovative Research for Communities and Clinical Excellence(CIRC2LE) Fukushima Medical UniversityFukushimaJapan

Objective The associations of physical multimorbidity with depressive symptoms have been investigated in a number of ***,whether patterns of chronic physical conditions have comparatively different associations with depressive symptoms remains *** study aimed to investigate the associations of physical multimorbidity patterns with depressive *** This study was designed as a nationwide cross-sectional survey in *** General sample of the Japanese *** Adult Japanese residents were selected by a quota sampling *** were analysed from 1788 residents who reported one or more chronic health *** Among four physical multimorbidity patterns:cardiovascular-renal metabolic(CRM),skeletal-articular digestive(SAD),respiratory-dermal(RDE)and malignant-digestive urologic(MDU),multivariable logistic regression analyses revealed that the RDE pattern showed the strongest association with depressive symptoms(aOR=1.68,95%CI:1.21 to 2.31 for the pattern score highest quartile,compared with the lowest quartile),followed by SAD and MDU patterns(aOR=1.41,95%CI:1.01 to 1.98 for the SAD pattern score highest quartile;1.41,95%CI:1.01 to 1.96 for the MDU pattern score highest quartile,compared with the lowest quartile).In contrast,the CRM pattern score was not significantly associated with depressive symptoms(aOR=1.31,95%CI:0.90 to 1.89 for the pattern score highest quartile,compared with the lowest quartile).Conclusions Physical multimorbidity patterns have different associations with depressive *** these patterns,patients with the RDE pattern may be at a higher risk for developing depressive *** study reinforces the evidence that cluster pattern of chronic health conditions is a useful measure for clinical management of multimorbidity as it is differently associated with mental health status,which is one of the crucial outcomes for multimorbid patients.

关键词： pattern nationwide sectional

Nitrogen Discharged from the Earth’s Interior Regions

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Journal of Modern Physics 2014年第2期5卷 75-81页

作者： Mikio fukuhara 1Research Institute for Electromagnetic Materials Sendai Japan 2Fracture and Reliability Research Institute Tohoku University Sendai Japan 3Green Device Laboratory Waseda University Tokyo Japan

The abundant nitrogen in the Earth’s atmosphere can be interpreted as the result of endothermic nuclear transmutation of carbon and oxygen atom pairs in (Ca, D) CO3 or CaCO3 aragonite lattice of Earth’s crust from the Archean era to the present time, by physical catalytic help of excited electrons e* generated by stick sliding due to plate tectonics and geoneutrinos ν by the radioactive decay of elements such as uranium and thorium in Earth’s mantle: through a nuclear attraction effect that is due to deuteron catalysis of nitrogen formation. The relationship between the critical temperature T and the critical pressure P for the nuclear transmutation is expressed as 7253 × e-0.014P, and the formation of nitrogen in the mantle is possible at temperatures ≥ 2510 K and pressure ≥ 58 GPa.

关键词： Nitrogen Earth Nuclear Transmutation Calcium Carbonate Geoneutrinos Excited Electrons Tectonics

Peritoneal dissemination of pancreatic cancer caused by endoscopic ultrasound-guided fine needle aspiration:A case report and literature review

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World Journal of Gastroenterology 2021年第3期27卷 294-304页

作者： Hideaki Kojima Minoru Kitago Eisuke Iwasaki Yohei Masugi Yohji Matsusaka hiroshi Yagi Yuta Abe Yasushi Hasegawa Shutaro Hori Masayuki Tanaka Yutaka Nakano Yusuke Takemura Seiichiro fukuhara Yoshiyuki Ohara Michiie Sakamoto Shigeo Okuda Yuko Kitagawa Department of Surgery Keio University School of MedicineTokyo 160-8582Japan Division of Gastroenterology and Hepatology Department of Internal MedicineKeio University School of MedicineTokyo 160-8582Japan Department of Pathology Keio University School of MedicineTokyo 160-8582Japan Department of Radiology Keio University School of MedicineTokyo 160-8582Japan

BACKGROUND Endoscopic ultrasound-guided fine needle aspiration(EUS-FNA)is a biopsy technique widely used to diagnose pancreatic tumors because of its high sensitivity and *** needle-tract seeding caused by EUS-FNA has been recently reported,dissemination of pancreatic cancer cells is generally considered to be a rare complication that does not affect patient ***,the frequency of dissemination and needle-tract seeding appears to have been *** present a case of peritoneal dissemination of pancreatic cancer due to preoperative *** SUMMARY An 81-year-old man was referred to the Department of Surgery of our hospital in Japan owing to the detection of a pancreatic mass on computed tomography during medical ***-gastric EUS-FNA revealed that the mass was an adenocarcinoma;hence laparoscopic distal pancreatectomy with lymphadenectomy was *** intraoperative peritoneal dissemination and liver metastasis were visually detected,and pelvic lavage cytology was negative for carcinoma *** postoperative surgical specimen was negative for carcinoma cells at the dissected margin and the cut end margin;however,pathological findings revealed adenocarcinoma cells on the peritoneal surface proximal to the needle puncture site,and the cells were suspected to be disseminated via ***,the patient received adjuvant therapy with S-1(tegafur,gimeracil,and oteracil potassium);however,computed tomography performed 5 mo after surgery revealed liver metastasis and cancerous *** patient received palliative therapy and died 8 mo after the *** The indications of EUS-FNA should be carefully considered to avoid iatrogenic dissemination,especially for cancers in the pancreatic body or tail.

关键词： Case report Pancreatic carcinoma Endoscopic ultrasound-guided fine needle aspiration Peritoneal dissemination Cancerous peritonitis Biopsy