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Important amino acid in the hemagglutinin glycoprotein of measles virus(MV)that governs hemadsorption

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Chinese Science Bulletin 1999年第7期44卷 612-617页

作者： Michiko watanabe Shigeharu Ueda Institute of Microbial Diseases Osaka University Osaka 565Institute of Microbial Diseases Osaka University Osaka 565 JapanJapan

Two strains of measles virus IMA and SMD that were isolated using B95a cell line show hemadsorption negative. After adaptation to Vero cells, these strains gain the ability to agglutinate AGM-RBC and show hemadsorption positive. Sequence analysis of these two kinds of virus reveals that the two strains all have a Ser (HAD negative) to Gly (HAD positive) mutation at position 546 in the H protein. Site-directed mutagenesis and expression in COS cells were used to confirm that the mutation Ser→Gly is responsible for hemadsorption alteration. Then the monoclonal antibody against CD46 was used to identify that this mutation also governs the binding function of MV H protein to CD46 receptor. The data provide a new important amino acid of MV H protein that governs the hemadsorption and binding to CD46 receptor.

关键词： H protein CD46 receptor hemadsorption site-directed mutagenesis.

Adaptive Learning with Large Variability of Teaching Signals for Neural Networks and Its Application to Motion Control of an Industrial Robot

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International Journal of Automation and computing 2011年第1期8卷 54-61页

作者： Fusaomi Nagata Keigo watanabe Department of Mechanical Engineering Faculty of Engineering Tokyo University of Science Department of Intelligent Mechanical Systems Graduate School of Natural Science and Technology Okayama University

Recently, various control methods represented by proportional-integral-derivative （PID） control are used for robotic control. To cope with the requirements for high response and precision, advanced feedforward controllers such as gravity compensator, Coriolis/centrifugal force compensator and friction compensators have been built in the controller. Generally, it causes heavy computational load when calculating the compensating value within a short sampling period. In this paper, integrated recurrent neural networks are applied as a feedforward controller for PUMA560 manipulator. The feedforward controller works instead of gravity and Coriolis/centrifugal force compensators. In the learning process of the neural network by using back propagation algorithm, the learning coefficient and gain of sigmoid function are tuned intuitively and empirically according to teaching signals. The tuning is complicated because it is being conducted by trial and error. Especially, when the scale of teaching signal is large, the problem becomes crucial. To cope with the problem which concerns the learning performance, a simple and adaptive learning technique for large scale teaching signals is proposed. The learning techniques and control effectiveness are evaluated through simulations using the dynamic model of PUMA560 manipulator.

关键词： Neural networks large-scale teaching signal sigmoid function adaptive learning servo system PUMA560 manipulator trajectory following control nonlinear control.

Observation of~100%valley-coherent excitons in monolayer MoS_(2) through giant enhancement of valley coherence time

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Light(Science & Applications) 2023年第8期12卷 1644-1650页

作者： Garima Gupta Kenji watanabe Takashi Taniguchi Kausik Majumdar Department of Electrical Communication Engineering Indian Institute of ScienceBangaloreIndia Research Center for Functional Materials National Institute for Materials ScienceTsukubaJapan international Center for Materials Nanoarchitectonics National Institute for Materials ScienceTsukubaJapan

In monolayer transition metal dichalcogenide semiconductors,valley coherence degrades rapidly due to a combination of fast scattering and inter-valley exchange *** leads to a sub-picosecond valley coherence time,making coherent manipulation of exciton a highly challenging task Using monolayer MoS_(2) sandwiched between top and bottom graphene,here we demonstrate fully valley-coherent excitons by observing~100%degree of linear polarization in steady state *** is achieved in this unique design through a combined effect of(a)suppression in exchange interaction due to enhanced dielectric screening,(b)reduction in exciton lifetime due to a fast inter-layer transfer to graphene,and(c)operating in the motional narrowing *** disentangle the role of the key parameters affecting valley coherence by using a combination of calculation(solutions of Bethe-Salpeter and Maiallle-Silva-Sham equations)and a careful choice of design of experiments using four different stacks with systematic variation of screening and exciton *** the best of our knowledge,this is the first report in which the excitons are found to be valley coherent in the entire lifetime in monolayer semiconductors,allowing optical readout of valley coherence possible.

关键词： coherent monolayer lifetime

THEORETICAL ASPECTS OF ELECTRON CAPTURE BY C6+ AND O8+ FROM H,He AND H2

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原子与分子物理学报 1991年第2期 1796-1809页

作者： Tsutomu watanabe Atomic Processes Laboratory Saitama-Ken 351-01 Japan The Institute of Physical and Chemical Research (RIKEN) Hirosawa Wako-shi

Many theoretical approaches to electron capture by C6+, a nd O8+fromthe targets H,He and H2are discussed from the practical stand point at thepresent *** validity of several representative methods for the calcul-ation of total and state selective partial cross sections is given. For the total cross section in many theoretical methods can be appliedand give reasonable *** the state selective partial cross section for adominant channel at low impact velocities manylevel coupled channel calcul-ations can be used and give reliable results,if it belongs to a dominant cha-nnel.

关键词： In THEORETICAL ASPECTS OF ELECTRON CAPTURE BY C AND O FROM H,He AND H2

Improvement in the information-oriented construction of temporary soil-retaining walls using sparse modeling

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Underground Space 2019年第3期4卷 210-224页

作者： Yu Otake Shinnosuke Kodama Shinya watanabe Niigata University Japan

This fundamental study investigates how“super-resolution”technology based on sparse modeling,which has attracted attention in various fields,can be applied to the information-oriented construction of temporary soil-retaining *** machine learning process adopted here is based on the analytical results of numerical computations that involve many preliminary assumptions related to soilretaining walls,rather than the collection of images utilized in the image reconstruction ***,bases for vectors related to the displacement of retaining walls are generated using efficient inverse analysis and“super-resolution”processing from sparse amounts of physical observation *** purpose is to improve the properties of the inverse problem by artificial interpolation based on numerical *** has been shown that the inverse analysis related to the displacement of retaining walls can be performed efficiently and that highly accurate predictions can be achieved even with limited physical *** general,the inverse analysis of retaining walls is an ill-posed ***,if the number of apparent observations reconverted by“super-resolution”technology exceeds the number of unknown parameters,then the displacement distribution of a retaining wall can be estimated *** original idea is to break down the inverse problem into two separate problems by addressing the earth pressure distribution acting on the retaining *** makes it possible to identify the part to which the nonlinear inverse problem can be applied and to facilitate the efficient estimation and interpretation of the results.

关键词： Information-oriented construction Temporary soil-retaining wall Super-resolution Sparse modeling

Geochemistry of Rare Earth Elements(REE) in the Weathered Crusts from the Granitic Rocks in Sulawesi Island, Indonesia

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Journal of Earth Science 2014年第3期25卷 460-472页

作者： Adi Maulana Kotaro Yonezu Koichiro watanabe Department of Geology Engineering Faculty of Engineering Hasanuddin University Department of Earth Resources Engineering Kyushu University

We report for the first time the geochemistry of rare earth elements（REE） in the weathered crusts of I-type and calc-alkaline to high-K（shoshonitic） granitic rocks at Mamasa and Palu region, Sulawesi Island, Indonesia. The weathered crusts can be divided into horizon A（lateritic profile） and B（weathered horizon）. Quartz, albite, kaolinite, halloysite and montmorrilonite prevail in the weathered crust. Both weathered profiles show that the total REE increased from the parent rocks to the horizon B but significantly decrease toward the upper part（horizon A）. LREE are enriched toward the upper part of the profile as shown by La/YbN value. However, HREE concentrations are high in horizon B1 in Palu profile. The total REE content of the weathered crust are relatively elevated compared to the parent rocks, particularly in the lower part of horizon B in Mamasa profile and in horizon B2 in Palu profile. This suggests that REE-bearing accessory minerals may be resistant against weathering and may remain as residual phase in the weathered crusts. The normalized isocon diagram shows that the mass balance of major and REE components between each horizon in Mamasa and Palu weathering profile are different. The positive Ce anomaly in the horizon A of Mamasa profile indicated that Ce is rapidly precipitated during weathering and retain at the upper soil horizon.

关键词： rare earth element geochemistry weathered crust granitic rock Sulawesi Indonesia.

Digital Terrain Modelling Using Corona and ALOS PRISM Data to Investigate the Distal Part of Imja Glacier,Khumbu Himal,Nepal

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Journal of Mountain Science 2011年第3期8卷 390-402页

作者： LAMSAL Damodar SAWAGAKI Takanobu watanabe Teiji Graduate School of Environmental Science Hokkaido University Faculty of Environmental Earth Science Hokkaido University

This study used Corona KH-4A and Advanced Land Observing Satellite (ALOS) PRISM images to generate digital terrain models (DTMs) of the distal part of Imja Glacier,where a few supraglacial ponds (～0.07 km 2) expanded into the large Imja Glacier Lake (Imja Tsho,～0.91 km 2) between 1964 and *** and subsequently derived topographical maps with contour intervals of 1 m were created from the high-resolution images (Corona in 1964 and ALOS in 2006) in the Leica Photogrammetric Suite (LPS) *** DTMs and topographic maps provided excellent representation of the elevation and micro-topography of the glacier surface,such as its supra-glacial ponds/lake,surface depressions,and moraine ridges,with an error of about +/-4 m (maximum).The DTMs produced from the Corona and ALOS PRISM images are suitable for use in studies of the surface change of *** topographical maps produced from the Corona data (1964) showed that part of the dead ice in the down-glacier area was even higher than the top of the lateral moraine ridges,while the glacier surface in the up-glacier area was noticeably lower than the moraine *** suggests more extensive melting of glacier ice in the up-glacier area before *** average lowering of the glacier surface from 1964 to 2006 was 16.9 m for the dead-ice area west of the lake and 47.4 m for the glacier surface east of the lake;between 1964 and 2002,the lake surface lowered by 82.3 *** figures represent average lowering rates of 0.4,1.1,and 2.2 m/year for the respective areas.

关键词： Imja Glacier Nepal Himalaya DTM Topographic map Surface lowering Corona ALOS PRISM

Synthesis of affinity column of phosphatidylinositol-3,4-diphosphate

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Chinese Journal of Chemistry 1997年第6期15卷 556-561页

作者： OZAKI Shoichiro watanabe Yutaka OGASAWARA Tomio Department of Chemistry Shandong University Jinan Shandong 250100 ChinaDepartment of Applied ChemistryFaculty of EngineeringEhime UniversityMatsuyama790JapanDepartment of Applied ChemistryFaculty of EngineeringEhime UniversityMatsuyama790Japan

Phosphatidylinositol polyphosphates (PIPx) are related with tyrosine kinase activation, cell proliferation and carcinogenesis. In order to investigate the action mechanism of PIPx, it is desirable to synthesize affinity column of PI-3,4-P-2, which is expected to be able to isolate the binding proteins of PI-3,4-P-2. Thyramine reacted with CH-Sepharose 4B giving column 13. The p-amino group of 3'-(1',2'-distearoyl-glyceryl)-1-(2-p-aminobenzyl)-3,4-di-O-phosphoryl-myo-inosityl phosphate (12) was diazotized, then diazo-coupled with column 13 to give PI-3,4-P-2 affinity column 14. This PI-3,4-P-2 affinity column is an effective tool to pick up binding proteins of PI-3,4-P-2.

关键词： phosphatydylinositol-3,4-diphosphate binding protein inositol PI-3,4-P-2-affinity

A NOTE ON THE UNIQUENESS AND THE NON-DEGENERACY OF POSITIVE RADIAL SOLUTIONS FOR SEMILINEAR ELLIPTIC PROBLEMS AND ITS APPLICATION

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Acta Mathematica Scientia 2018年第4期38卷 1121-1142页

作者： Shinji ADACHI Masataka SHIBATA Tatsuya watanabe Department of Mathematical and Systems Engineering Faculty of Engineering Shizuoka University 3-5-1 Johoku Naka-ku Hamarnatsu 432-8551 Japan Department of Mathematics Tokyo Institute of Technology 2-12-1 Oh-okayama Meguro-ku Tokyo 15248551 Japan Department of Mathematics Faculty of Science Kyoto Sangyo University Motoyama Kamigamo Kita-ku Kyoto 603-8555 Japan

In this paper, we are concerned with the uniqueness and the non-degeneracy of positive radial solutions for a class of semilinear elliptic equations. Using detailed ODE anal- ysis, we extend previous results to cases where nonlinear terms may have sublinear growth. As an application, we obtain the uniqueness and the non-degeneracy of ground states for modified SchrSdinger equations.

关键词： positive radial solution uniqueness non-degeneracy shooting method