检索结果-南通市图书馆

Recent advances in the surgical treatment of hepatocellular carcinoma

World Journal of Gastroenterology 2014年第39期20卷 14381-14392页

作者： Zenichi Morise Norihiko Kawabe hirokazu tomishige Hidetoshi Nagata Jin Kawase Satoshi Arakawa Rie Yoshida Masashi Isetani Department of Surgery Fujita Health University School of Medicine Banbuntane Houtokukai Hospital Nagoya 454-8509 Japan

Hepatocellular carcinoma(HCC) is the most common primary liver malignancy. The treatment of HCC is complex and complicated by the severity of associated chronic liver disease, the stage of HCC, and the clinical condition of the patient. Liver resection(LR) is one of the most efficient treatments for patients with HCC, with an expected 5-year survival of 38%-61% depending on the stage of the disease. Improved liver function assessment, increased understanding of segmental liver anatomy from advanced imaging studies, and surgical technical progress are important factors that have led to reduced mortality in patients with HCC. The indication for LR may be expanded due to emerging evidences from laparoscopic hepatectomies and combined treatments with newly developed chemotherapies. Liver transplantation(LT) is considered as an ideal treatment for removal of existing tumors and the injured/preneoplastic underlying liver tissue with impaired liver function and the risk of multicentric carcinogenesis that results from chronically injured liver. However, LT is restricted to patients with minimal risk of tumor recurrence under immunosuppression. The expansion of criteria for LT in HCC patients is still under trial and discussion. Limited availability of grafts, as well as the risk and the cost of transplantation have led to considerable interest in expansion of the donor pool, living donor-related transplantation, and combined treatment involving LR and LT. This highlight presents evidence concerning recent studies evaluating LR and LT in HCC patients. In addition, alternative therapies for the treatment of early stage tumors and the management of patients on transplant waiting lists are discussed.

关键词： Hepatocellular carcinoma Surgical treatment Hepatectomy Liver transplantation Laparoscopic hepatectomy Tumor thrombi Chemotherapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pure laparoscopic hepatectomy as repeat surgery and repeat hepatectomy

引用

World Journal of Gastroenterology 2015年第3期21卷 961-968页

作者： Masashi Isetani Zenichi Morise Norihiko Kawabe hirokazu tomishige Hidetoshi Nagata Jin Kawase Satoshi Arakawa Department of Surgery Fujita Health University School of MedicineBanbuntane Houtokukai HospitalAichiNagoya 454-8509Japan

AIM:To assess clinical outcomes of laparoscopic hepatectomy(LH) in patients with a history of upper abdominal surgery and repeat ***:This study compared the perioperative courses of patients receiving LH at our institution that had or had not previously undergone upper abdominal *** the 80 patients who underwent LH,22 had prior abdominal surgeries,including hepatectomy(n = 12),pancreatectomy(n = 3),cholecystectomy and common bile duct excision(n = 1),splenectomy(n = 1),total gastrectomy(n = 1),colectomy with the involvement of transverse colon(n = 3),and extended hysterectomy with extensive lymph-node dissection up to the upper abdomen(n = 1).Clinical indicators including operating time,blood loss,hospital stay,and morbidity were compared among the ***:Eighteen of the 22 patients who had undergone previous surgery had severe adhesions in the area around the ***,there were no conversions to laparotomy in this *** the 58 patients without a history of upper abdominal surgery,the median operative time was 301 min and blood loss was 150 m *** patients with upper abdominal surgical history or repeat hepatectomy,the operative times were 351 and 301 min,and blood loss was 100 and 50 m L,*** median postoperative stay was 17,13 and 12 d for patients with no history of upper abdominal surgery,patients with a history,and patients with repeat hepatectomy,*** were five cases with complications in the group with no surgical history,compared to only one case in the group with a prior *** were no statistically significant differences in the perioperative results between the groups with and without upper abdominal surgical history,or with repeat ***:LH is feasible and safe in patients with a history of upper abdominal surgery or repeat hepatectomy.

关键词： Chronic liver disease Laparoscopic hepatectomy Liv

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Case report of the fourth laparoscopic liver resection and review of repeat laparoscopic resection for recurrent hepatocellular carcinoma in cirrhotic liver

引用

Hepatoma Research 2016年第1期2卷 253-258页

作者： Zenichi Morise Masashi Isetani Norihiko Kawabe hirokazu tomishige Hidetoshi Nagata Satoshi Arakawa Masahiro Ikeda Kenshiro Kamio Department of Surgery Fujita Health University School of MedicineToyoakeAichi 470-1192Japan Department of Surgery Fujita Health University Banbuntane Houtokukai HospitalNagoyaAichi 454-8509Japan

A 73-year-old woman with liver cirrhosis caused by hepatitis C virus(HCV)underwent treatment of three hepatocellular carcinomas(HCCs)in liver segment 4,following three previous laparoscopic liver resections(LLRs)over 73 ***-enhanced computed tomography showed three 0.5-1.2 cm HCCs deep within the portal territories of subsegments 4a and *** patient underwent laparoscopic resection of 4a and 4b,with the preservation of the portal branch to 4c,after minimal adhesiolysis around segment *** operation lasted 284 min,there was 50 mL of intra-operative bleeding and her recovery was *** was well,had experienced no recurrence and was HCV-negative,after taking oral anti-HCV therapy,21 months *** is associated with fewer adhesions after surgery and requires less adhesiolysis,because the laparoscope and forceps can be used in the small spaces between *** present patient underwent four LLRs over 6 years without severe deterioration of liver functional *** is a useful localized therapy,which can be performed repeatedly and may prolong the survival of patients with multicentric metachronous HCCs.

关键词： Laparoscopic liver resection,repeat liver resection hepatocellular carcinoma liver cirrhosis anatomical liver resection subsegmentectomy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

X-ray diagnosis with a bloating agent for foreign object ingestion

引用

World Journal of Clinical Cases 2014年第5期2卷 157-159页

作者： hirokazu tomishige Zenichi Morise Tatsuya Suzuki Fujio Hara Masahito Hibi Takazumi Kato Takashi Hashimoto Department of Surgery Fujita Health University School of MedicineBanbuntane Houtokukai HospitalNagoyaAichi 454-8509Japan Department of Pediatric Surgery Fujita Health University School of MedicineToyoakeAichi 470-1192Japan

The location of an ingested foreign object is often difficult to determine by X-ray if gastric air bubbles are not clear in the *** that provide negative contrast can facilitate precise object localization,which is important for object retrieval and treatment of the *** case report describes a male child,2 years and 2 mo of age,who accidentally swallowed a lithium battery while playing at home.A plain X-ray showed that the battery was in the abdomen,but it was unclear whether the object was still inside the stomach.A second X-ray examination performed after oral administration of a bloating agent to produce expansion of the stomach and provide negative contrast confirmed that the ingested battery was still in the *** battery was then carefully removed using magnetic and balloon catheters under fluoroscopic *** case report describes the successful use of an orally administered bloating agent without pain to the child in orderto determine the precise location of a foreign object in the abdomen.

关键词： Accidental ingestion Bloating agent X-ray Minimal invasion Foreign object

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Factors Impacting Participatory Post‑Disaster Relocation and Housing Reconstruction:The Case of Tsholotsho District,Zimbabwe

引用

International Journal of Disaster Risk Science 2024年第1期15卷 58-72页

作者： Nombulelo Kitsepile Ngulube hirokazu Tatano Subhajyoti Samaddar Department of Social Informatics Graduate School of InformaticsKyoto UniversityKyoto 606-8507Japan Disaster Prevention Research Institute(DPRI) Kyoto UniversityKyoto 611-0011Japan

Relocation is not typically considered the best planning option for post-disaster reconstruction and rehabilitation,but it may be necessary if the site has suffered severe damage or is at imminent *** is a growing recognition that strong community participation is necessary in the post-disaster relocation decision-making process since relocation can have detrimental effects on a community’s livelihood,cultural system,and way of life,among ***,the realization of this still needs to be *** of yet,few studies have examined a comprehensive account of meaningful community engagement in post-disaster relocation and reconstruction,particularly in developing *** study investigated what factors influenced local communities’ participation in post-disaster relocation and reconstruction works after the 2017Cyclone Dineo flood disaster in the Tsholotsho District of *** research methods such as face-to-face interviews,observations,and focus groups were used to collect qualitative data from a purposive sample of 25 community members and 6 *** empirical investigation showed that despite the fact that the relocation project was conceived as a community-centered project,there was no meaningful community engagement,due to the absence of a participatory framework or planning guidelines for stakeholder engagement,as well as the lack of political willingness among government *** study concluded that the lack of community involvement led to local communities abandoning the reconstruction sites because relocation projects failed to accommodate the cultural beliefs,place attachments,and livelihood concerns of local *** study suggested that it is imperative to enhance the awareness of government officials and other stakeholders about the importance of community participation for the effective implementation of post-disaster relocation *** community participation can also provide avenues fo

关键词： Community rehabilitation Housing reconstruction-Participatory relocation Zimbabwe

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The chemical structures,biosynthesis,and biological activities of secondary metabolites from the culinary-medicinal mushrooms of the genus Hericium:a review

引用

Chinese Journal of Natural Medicines 2024年第8期22卷 676-698页

作者： QI Jianzhao WU Jing KANG Shijie GAO Jingming hirokazu Kawagishi LIU Hongwei LIU Chengwei Key Laboratory for Enzyme and Enzyme-Like Material Engineering of Heilongjiang College of Life ScienceNortheast Forestry UniversityHarbin 150040China Shaanxi Key Laboratory of Natural Products&Chemical Biology College of Chemistry&PharmacyNorthwest A&F UniversityYangling 712100China Faculty of Agriculture Shizuoka UniversityShizuoka 422-8529Japan State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China

Fungal phytochemicals derived from higher fungi,particularly those from the culinary-medicinal genus Hericium,have gained significant attention in drug discovery and *** review aims to provide a comprehensive analysis of the chemical structures,biosynthetic pathways,biological activities,and pharmacological properties of monomeric compounds isolated from Hericium *** the past 34 years,253 metabolites have been identified from various Hericium species,including cyathane diterpenes,alkaloids,benzofurans,chromenes,phenols,pyrones,steroids,and other miscellaneous *** investigations into the biosynthesis of erinacines,a type of cyathane diterpene,have led to the discovery of novel cyathane *** research has highlighted the biological activities and pharmacological properties of Hericium-derived compounds,with particular emphasis on their neuroprotective and neurotrophic effects,immunomodulatory capabilities,anti-cancer activity,antioxidant properties,and antimicrobial *** A,in particular,has been extensively ***,transcriptomic,and proteomic analyses of Hericium species have facilitated the discovery of new compounds and provided insights into enzymatic reactions through genome *** diverse chemical structures and biological activities of Hericium compounds underpin their potential applications in medicine and as dietary *** review not only advances our understanding of Hericium compounds but also encourages further research into Hericium species within the realms of medicine,health,functional foods,and agricultural *** broad spectrum of compound types and their diverse biological activities present promising opportunities for the development of new pharmaceuticals and edible products.

关键词： Hericium Secondary metabolites Biological activity Biosynthesis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Laparoscopic liver resection for the treatment of hepatocellular carcinoma

引用

World Journal of Surgical Procedures 2015年第1期5卷 137-141页

作者： Norihiko Kawabe Zenichi Morise hirokazu tomishige Hidetoshi Nagata Jin Kawase Satoshi Arakawa Masashi Isetani Department of Surgery Fujita Health University School of MedicineBanbuntane Houtokukai Hospital

Accumulation of experiences and technological advances after the first report of laparoscopic liver resection(LLR) are now revealing the characteristics and specific advantages of this approach, especially for hepatocellular carcinoma(HCC) patients with chronic liver diseases(CLD). Inlaparoscopic approach, there are minimum needs for:(1) laparotomy and dissection of the attachments and adhesion which may cause destructions in the collateral blood and lymphatic flows; and(2) compression of the liver which may cause parenchymal damage for the liver resection(LR). These are especially beneficial for the patients with CLD. LLR results in minimal postoperative ascites and the other complications, which could potentially lead to lowering the risk of fatal liver failure. These characteristics of LLR facilitate surgical treatment application to the patients of HCC with background CLD. Laparoscopic approach also results in improved vision and manipulation in a small operative field under several conditions, including the cases where it is necessary to perform repeat LR between adhesions. These characteristics make LLR safer and more accessible to the repeat treatment, such as multicentric and metachronous lesions in the cirrhotic liver. These advantages of LLR indicate it is a superior method than open LR under certain conditions in patients of HCC with background CLD.

关键词： Laparoscopic hepatectomy Hepatocellular carcinoma Liver cirrhosis Chronic liver disease Liver tumor Liver resection Repeat hepatectomy Bridging therapy to transplantation Ascites Postoperative liver failure

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

引用

Journal of Computer and Communications 2024年第5期12卷 42-52页

作者： hirokazu Ito Yuko Yasuhara Tetsuya Tanioka Department of Nursing Institute of Biomedical Sciences Tokushima University Graduate School Tokushima Japan

Lengthening periods of hospitalization, increasing numbers of patients with age-related complications, and a shortage of nursing staff have been of great concern in medical psychiatry in Japan. Under these circumstances, countries such as Japan that face a super-aging society and a decline in the working-age population, have been recommended for use of advanced information and communications technology (ICT) to improve the efficiency of medical treatment and care. This study aims to develop the “Monitoring Application for Inappropriate Expressions in Nursing Records” for using PsyNACS©, which will enable psychiatric nursing plans to harness the advantages of ICT. The functions considered necessary are as follows: 1) identification of users who enter information;2) a necessary database for lists of inappropriate expressions;3) development of a matching function to recommend proper writing input and a warning function;and 4) a management function for an inappropriate expression list database. A demonstration experiment for developing the application in this study was conducted at a specialized psychiatric hospital. To introduce them to the application, nurses and nurse managers were informed about the system developed in this study, and a survey regarding their opinions on the functions of the application was conducted with ten nurse managers. The results were evaluated in terms of usefulness for nursing care, documentation, and the education of nurses from an ethical perspective. This study suggests that matching their input with an inappropriate expression database will allow nurses to record more appropriate expressions. From an ethical perspective, the ability to use appropriate expressions makes records more likely to withstand disclosure requests from patients and their families.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pure laparoscopic hepatectomy for hepatocellular carcinoma with chronic liver disease

引用

World Journal of Hepatology 2013年第9期5卷 487-495页

作者： Zenichi Morise Norihiko Kawabe Jin Kawase hirokazu tomishige Hidetoshi Nagata Hisanori Ohshima Satoshi Arakawa Rie Yoshida Masashi Isetani Department of Surgery Fujita Health University School of MedicineBanbuntane Houtokukai HospitalAichi 454-8509Japan

Pure laparoscopic hepatectomy is a less invasive procedure than conventional open hepatectomy for the resection of hepatic lesions. Increases in experiences with the technique, in combination with advances in technology, have promoted the popularity of pure laparoscopic hepatectomy. However, indications for usage and potential contraindications of the procedure remain unresolved. The characteristics and specific advantages of the procedure, especially for hepatocellular carcinoma(HCC) patients with chronic liver diseases,are reviewed and discussed in this paper. For cirrhotic patients with liver tumors, pure laparoscopic hepatectomy minimizes destruction of the collateral blood and lymphatic flow from laparotomy and mobilization, and mesenchymal injury from compression. Therefore, pure laparoscopic hepatectomy has the specific advantage of minimal postoperative ascites production that leads to lowering the risk of disturbance in water or electrolyte balance and hypoproteinemia. It minimizes complications that routinely trigger postoperative serious liver failure. Under adequate patient positioning and port arrangement, the partial resection of the liver in the area of subphrenic space, peri-inferior vena cava area or next to the attachment of retro-peritoneum is facilitated in pure laparoscopic surgery by providing good vision and manipulation in the small operative ***, the features of reduced post-operative adhesion, good vision, and manipulation within the small area between the adhesions make this procedure safer in the context of repeat hepatectomy *** improved features are especially advantageous for patients with liver cirrhosis and multicentric and/or metachronous HCCs.

关键词： Laparoscopic hepatectomy Hepatocellular carcinoma Liver cirrhosis Chronic liver disease Liver Tumor Liver resection Repeat hepatectomy Bridging therapy to transplantation Ascites Postoperative liver failure

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Caudal approach to pure laparoscopic posterior sectionectomy under the laparoscopy-specific view

引用

World Journal of Gastrointestinal Surgery 2013年第6期5卷 173-177页

作者： hirokazu tomishige Zenichi Morise Norihiko Kawabe Hidetoshi Nagata Hisanori Ohshima Jin Kawase Satoshi Arakawa Rie Yoshida Masashi Isetani Department of Surgery Fujita Health University School of MedicineBanbuntane Houtokukai HospitalNagoya Aichi 454-8509Japan

AIM:To study our novel caudal approach laparoscopic posterior-sectionectomy with parenchymal transection prior to mobilization under laparoscopy-specific ***:Points of the procedure are:(1) Patients are put in left lateral position and posterior sector is not mobilized;(2) Glissonian pedicle of the sector is encircled and clamped extra-hepatically and divided afterward during the transection;(3) Dissection of inferior vena cava(IVC) anterior wall behind the liver is started from ***,liver transection is performed to search right hepatic vein(RHV) from caudal;(4) Liver transection proceeds to the bifurcation of the vessels from caudal to cranial,exposing the surfaces of IVC and *** the remnant liver sinks down,the cutting surface is well-opend;and(5) After the completion of transection,dissection of the resected liver from retroperitoneum is easily performed using the *** approach was performed for a 63 years old woman with liver metastasis close to ***:RHV exposure is required for R0 resection of the *** the cutting plane is horizontal in supine position and the gravity obstructs the exposure in the small subphrenic space,the use of specific characteristics of laparoscopic hepatectomy,such as the good vision for the dorsal part of the liver and IVC and facilitated dissection using the gravity with the patient positioning,made the complete RHV exposure during the liver transection easy to *** operation time was 341 min and operative blood loss was 1356 *** postoperative hospital stay was uneventfull and she is well without any signs of recurrences 14 mo after ***:The new procedure is feasible and useful for the patients with tumors close to RHV and the need of the exposure of RHV.

关键词： Laparoscopic hepatectomy Posterior sectionectomy Caudal approach Right hepatic vein Mobilization of the liver Left lateral position

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：