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Thermoelectric Properties of Silver Antimonate with Mixed Valency of Antimony

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Journal of Materials Science and Chemical Engineering 2017年第1期5卷 121-128页

作者： Kensuke Ozawa hirofumi Kakemoto Hiroshi Irie Interdisciplinary Graduate School of Medicine and Engineering University of Yamanashi Yamanashi Japan Clean Energy Research Center University of Yamanashi Yamanashi Japan

Silver (Ag) and silver antimonate (AgSbO3) composites with different amounts of Sb3+ were synthesized by normal sintering with the aim of realizing a thermoelectric material. The electrical conductivity (σ) increased in the sample containing larger amount of Sb3+, whereas Seebeck coefficient (S) decreased. Producing Sb3+ caused the generation of oxygen vacancies in the material, and thus the corresponding donor levels are created in the bandgap, providing more conduction electrons. The conductive Ag particles would contribute to the conduction path as bypasses for carrier transport. The thermal conductivity (κ) was slightly lower in the presence of Ag defects in AgSbO3.

关键词： Thermoelectric Material Silver Antimonate Seebeck Coefficient Electrical Conductivity Thermal Conductivity

Effects of Moisture Content on Cyclic Shear Properties of Soils during Epicentral Earthquakes

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Journal of Civil Engineering and Architecture 2011年第12期5卷 1091-1102页

作者： hirofumi Toyota Ayaka Susami Susumu Takada Department of Civil and Environmental Engineering Nagaoka University of Technology Japan

Numerous landslides occurred in hilly and mountainous areas during the 2004 Niigata-ken Chuetsu Earthquake. Social problems developed when many towns became isolated because landslides cut offtraffic and public service lifelines. The hilly areas are composed mainly alternate layer of soft sandstone and mudstone deposited in quaternary or tertiary period. This geomorphology formed by folding presents a prominent landslide area in this region. This area has been utilized as rice terraces or carp breeding ponds because of plenty of water in the ground all the time. In addition, there was rainfall of more than 100 mm caused by Typhoon No. 23 two days before the earthquake in Chuetsu area. Block samples were extracted from the failure sites. The samples obtained were mainly low-cemented sandy soils. Triaxial tests of the samples under saturated and unsaturated conditions were conducted to examine the soils＇ strength properties and estimate the indices for slope stability.

关键词： Triaxial test unsaturated soil landslide site investigation geology

A Transparent Polyimide Film as a Biological Cell Culture Sheet with Microstructures

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Journal of Biomaterials and Nanobiotechnology 2014年第1期5卷 17-23页

作者： Hirotaka Maenosono hirofumi Saito Yasushiro Nishioka Department of Precision Machinery College of Science and Technology Nihon University Chiba Japan

The research on stem cell cultures has attracted much attention due to the recent development of regenerative medicine. Therefore, higher functionalities for devices used for culturing cells are strongly demanded. In this study, we fabricated cell culture sheets using transparent polyimide (PI), parylene (PA), and polyetheretherketone (PEEK) to make polymer materials that had microstructures. We then cultured stromal marrow cells (OP9) on them and investigated the cell alignment within the microstructures. Hot embossing was used to fabricate the microstructures with a width and depth of 5 μm on the polymer substrates. Cultivation of the cells was confirmed on the transparent PI and PA sheets, however, it was not observed on the PEEK sheet. Slight alignment of the cells was also observed along with the microstructures.

关键词： Transparent Polymide Parylene Polyetheretherketone OP9 Cell Hot Embossing

Cytokines in adipose-derived mesenchymal stem cells promote the healing of liver disease

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World Journal of Stem Cells 2018年第11期10卷 146-159页

作者： Saifun Nahar Yoshiki Nakashima Chika Miyagi-Shiohira Takao Kinjo Zensei Toyoda Naoya Kobayashi Issei Saitoh Masami Watanabe hirofumi Noguchi Jiro Fujita Department of Infectious Respiratory and Digestive Medicine Graduate School of Medicine University of the Ryukyus Okinawa 903-0215 Japan Department of Regenerative Medicine Graduate School of Medicine University of the Ryukyus Okinawa 903-0215 Japan Department of Basic Laboratory Sciences School of Health Sciences in the Faculty of Medicine University of the Ryukyus Okinawa 903-0215 Japan Okayama Saidaiji Hospital Okayama 704-8192 Japan Division of Pediatric Dentistry Graduate School of Medical and Dental Science Niigata University Niigata 951-8514 Japan Department of Urology Okayama Univer sity Graduate School of Medicine Dentistry and Pharmaceutical Sciences Okayama 700-8558 Japan

Adipose-derived mesenchymal stem cells （ADSCs） are a treatment cell source for patients with chronic liver injury. ADSCs are characterized by being harvested from the patient’s own subcutaneous adipose tissue, a high cell yield （ i.e. , reduced immune rejection res-ponse）, accumulation at a disease nidus, suppression of excessive immune response, production of various growth factors and cytokines, angiogenic effects, anti-apoptotic effects, and control of immune cells via cell-cell interaction. We previously showed that conditioned medium of ADSCs promoted hepatocyte proliferation and improved the liver function in a mouse model of acute liver failure. Furthermore, as found by many other groups, the administration of ADSCs improved liver tissue fbrosis in a mouse model of liver cirrhosis. A comprehensive protein expression analysis by liquid chromatography with tandem mass spectrometry show-ed that the various cytokines and chemokines produced by ADSCs promote the healing of liver disease. In this review, we examine the ability of expressed protein com-ponents of ADSCs to promote healing in cell therapy for liver disease. Previous studies demonstrated that ADSCs are a treatment cell source for patients with chronic liver injury. This review describes the various cytokines and chemokines produced by ADSCs that promote the healing of liver disease.

关键词： Cell transplantation therapy Cytokine Hepatocytes Liquid chromatography with tandem mass spectrometry Liver cirrhosis Adipose-derived mesenchymal stem cells

Study on Deactivation and Regeneration of Modified Red Mud Catalyst Used in Biodiesel Production

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Green and Sustainable Chemistry 2017年第4期7卷 247-258页

作者： Agus Wahyudi Winarto Kurniawan hirofumi Hinode Department of International Development Engineering Tokyo Institute of Technology Tokyo Japan R & D Centre for Mineral and Coal Technology Ministry of Energy and Mineral Resources Bandung Indonesia

Deactivation of solid catalyst often occurs in biodiesel production. In this work, deactivated modified red mud catalysts used in biodiesel production were regenerated with hexane and calcination treatments. The deactivated and regenerated catalysts were characterized using XRD, FTIR, SEM, TG, N2 adsorption, measured for their basic strength, and tested in the transesterification of canola oil. The results revealed that the main cause of the catalyst deactivation is due to obstruction of the active sites by contaminants. The regeneration by washing with hexane followed by calcination can effectively improve the properties of the deactivated catalyst and increase its catalytic activity.

关键词： Modified Red Mud Catalyst Deactivation Regeneration Biodiesel

MEC-IoT-Healthcare: Analysis and Prospects

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Computers, Materials & Continua 2023年第6期75卷 6219-6250页

作者： Hongyuan Wang Mohammed Dauwed Imran Khan Nor Samsiah Sani Hasmila Amirah Omar hirofumi Amano Samih M.Mostafa College of Computer Science Guangdong University of Science and TechnologyDongGuan523083China Department of Medical Instrumentation Techniques Engineering Dijlah University CollegeBaghdadIraq Department of Electrical Engineering University of Engineering&TechnologyPeshawar814Pakistan Center for Artificial Intelligence Technology Faculty of Information Science and TechnologyUniversiti Kebangsaan Malaysia43600BangiSelangorMalaysia Research Institute for Information Technology Kyushu UniversityFukuoka819-0395Japan Computer Science-Mathematics Department Faculty of ScienceSouth Valley UniversityQena83523Egypt

Physical sensors,intelligent sensors,and output recommenda-tions are all examples of smart health technology that can be used to monitor patients’health and change their *** health is an Internet-of-Things(IoT)-aware network and sensing infrastructure that provides real-time,intelligent,and ubiquitous healthcare *** of the rapid development of cloud computing,as well as related technologies such as fog computing,smart health research is progressively moving in the right ***,fog computing,IoT sensors,blockchain,privacy and security,and other related technologies have been the focus of smart health research in recent *** the moment,the focus in cloud and smart health research is on how to use the cloud to solve the problem of enormous health data and enhance service performance,including cloud storage,retrieval,and calculation of health big *** article reviews state-of-the-art edge computing methods that has shifted to the collection,transmission,and calculation of health data,which includes various sensors and wearable devices used to collect health data,various wireless sensor technologies,and how to process health data and improve edge performance,among other ***,the typical smart health application cases,blockchain’s application in smart health,and related privacy and security issues were reviewed,as well as future difficulties and potential for smart health *** comparative analysis provides a reference for the the mobile edge computing in healthcare systems.

关键词： IoT mobile-edge computing cloud computing e-health

Interaction of <i>Helicobacter pylori</i>Cell Membrane with Non-Esterified Cholesterol and Other Steroids

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Open Journal of Medical Microbiology 2013年第1期3卷 70-79页

作者： hirofumi Shimomura Kouichi Hosoda Yoshikazu Hirai Division aof Bacteriology Department of Infection and Immunity Jichi Medical University Tochigi Japan Division of Bacteriology Department of Infection and Immunity Jichi Medical University Tochigi Japan

Helicobacter pylori performs the unique action of assimilating exogenous non-esterified cholesterol into its cell membrane. This bacterium aggressively incorporates non-esterified cholesterol into the membrane, induces its glucosylation, and uses both non-esterified cholesterol and glucosylated cholesterols as membrane lipid compositions. The reason for this assimilation of non-esterified cholesterol into the cell membrane of H. pylori has eluded investigators for many years. Recent hypotheses posit that the sterol-uptake and sterol-glucosylation contribute to the survival of H. pylori cells in different ways. The incorporation of the non-esterified cholesterol into the cell membrane fortifies the resistance of H. pylori against the antibacterial actions of phosphatidylcholines, antibiotics, and bile salts. In parallel, the glucosylation of the non-esterified cholesterol incorporated into the cell membrane serves H. pylori in two ways. First, it helps the bacterium evade host immune responses, such as phagocytosis by macrophages and activation of antigen-specific T cells. Second, it detoxifies sterols fatal to the bacterium via a novel action of sterol glucosylation recently described in another report from our group. The reluctance of H. pylori to absorb esterified cholesterol remains unexplained. A recent study by our group has demonstrated that the phosphatidylethanolamine (PE) in the outer membrane of H. pylori serves as a steroid-binding lipid the incorporation of non-esterified cholesterol into the membrane. We have also discovered that the myristic acid (C14:0) molecule attached to the PE of this bacterium plays an important role in the selective binding of non-esterified cholesterol but not esterified cholesterol.

关键词： Helicobacter pylori Cholesterol-α-Glucosyltransferase Phosphatidylethanolamine

Ectopic porcine spermatogenesis in murine subcutis： tissue grafting versus cell-injection methods

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Asian Journal of Andrology 2009年第3期11卷 317-323页

作者： Takeshi Watanabe hirofumi Hayashi Kaoru Kita Yoshinobu Kubota Takehiko Ogawa Department of Urology Ashigarakami Hospital Kanagawa 258-0003 Japan Department of Urology Yokohama Minami Kyousai Hospital Yokohama 236-0032 Japan Department of Urology Yokohama City University Graduate School of Medicine Yokohama 236-0004 Japan

Fragments of testis tissue from immature animals grow subcutaneous areas of immunodeficient mice. The same results testes of rodents are injected into the subcutis of nude mice. and develop spermatogenesis when grafted onto are obtained when dissociated cells from immature Those cells reconstitute seminiferous tubules and facilitate spermatogenesis. We compared these two methods, tissue grafting and cell-injection methods, in terms of the efficiency of spermatogenesis in the backs of three strains of immunodeficient mice, using neonatal porcine testicular tissues and cells as donor material. Nude, severe combined immunodeficient （SCID） and NOD/Shi- SCID, IL-2Rγc^null （NOG） mice were used as recipients. At 10 months after surgery, the transplants were examined histologically. Both grafting and cell-injection methods resulted in porcine spermatogenesis on the backs of recipient mice; the percentage of spermatids present in the transplants was 67% and 22%, respectively. Using the grafting method, all three strains of mice supported the same extent of spermatogenesis. As for the cell- injection method, although SCID mice were the best host for supporting reconstitution and spermatogenesis, any difference from the other strains was not signifcant. As NOG mice did not show any better results, the severity of immunodeficiency seemed to be irrelevant for supporting xeno-ectopic spermatogenesis. Our results confirmed that tubular reconstitution is applicable to porcine testicular cells. This method as well as the grafting method would be useful for studying spermatogenesis in different kinds of animals.

关键词： pigs seminiferous tubule spermatogenesis xeno-transplantation

Identification of Model Parameters of Vaporized Hydrogen Peroxide Decomposi-tion Flux on Building Materials for Compu-tational Fluid Dynamics

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Journal of Environmental Protection 2016年第2期7卷 212-229页

作者： Kazuhide Ito Sung-Jun Yoo hirofumi Horata Interdisciplinary Graduate School of Engineering Science Kyushu University Fukuoka Japan

To maintain healthy and sanitary indoor air quality, development of effective decontamination measures for the indoor environment is important and hydrogen peroxide is often used as decontamination agent in healthcare environment. In this study, we focused on the decomposition phenomena of vaporized hydrogen peroxide on wall surfaces in indoor environment and discussed a wall surface decomposition model for vaporized hydrogen peroxide using computational fluid dynamics to simulate the concentration distributions of vaporized hydrogen peroxide. A major drawback to using numerical simulations is the lack of sufficient data on boundary conditions for various types of building materials and hence. We also conducted the fundamental chamber experiment to identify the model parameters of wall surface decomposition model for targeting five types of building materials.

关键词： Vaporized Hydrogen Peroxide Computational Fluid Dynamics Wall Surface Decomposition Model Chamber Experiment