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Oxidation behavior of ferritic/martensitic steels in flowing supercritical water

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Journal of Materials Science & Technology 2021年第5期64卷 114-125页

作者： Quanqiang Shi Wei Yan Yanfen Li Naiqiang Zhang Yiyin Shan Ke Yang hiroaki abe Key Laboratory of Nuclear Materials and Safety Assessment Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China Key Laboratory of Condition Monitoring and Control for Power Plant Equipment of Ministry of Education North China Electric Power UniversityBeijing 102206China Institute of Metal Research Chinese Academy of SciencesShenyang 110016China School of Engineering The University of TokyoTokaiIbaraki319-1188Japan

The oxidation behavior of two Ferritic/Martensitic(F/M)steels including novel SIMP steel and commercial P91 steel were investigated by exposure to flowing deaerated supercritical water(SCW)at 700℃for up to 1000 *** kinetic weight gain curves follow parabolic and near-cubic rate equations for SIMP and P91 steels,respectively.X-Ray Diffraction analysis showed the presence of magnetite and a spinel phase in flowing SCW for both *** morphology and structure of the oxide scales formed on these two steels were *** relationship between the microstructure and oxidation behavior and the reason that SIMP steel showed better oxidation resistance than P91 steel were discussed.

关键词： Ferritic/martensitic steel Supercritical water Oxidation Oxide scale SIMP steel

The Reliability of Assessment of Ki-67 Expression on Core Needle Biopsy and the Surgical Specimens of Invasive Breast Cancer: Comparison of Local Pathologists’ Assessment and Central Review

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Journal of Cancer Therapy 2012年第5期3卷 841-845页

作者： Yoshio Mizuno Tsuneo Natori Naoko Takeda Junichi Yamada hiroaki abe Yuko Inoue Hiroshi Seto Kazuhiko Sato Clinical Testing Business Testing Division Special Reference Laboratories Inc. Tokyo Japan Department of Breast Oncology Tokyo-West Tokushukai Hospital Tokyo Japan Department of Clinical Pathology Tokyo-West Tokushukai Hospital Tokyo Japan Inoue Ladies Clinic Tokyo Japan Seto Hospital Saitama Japan

Purpose: The aim of this study was to assess the reliability of Ki-67 expression on core needle biopsy (CNB) and the surgical specimens of invasive breast cancer. We examined the concordance rate of Ki-67 expressions, hormone receptors, and human epidermal growth factor receptor 2 (HER2) status from a CNB with from a surgery in invasive breast cancer. Methods: A retrospective study was conducted on a clinical database of patients who underwent surgery for early breast cancer. Of these, 193 patients who underwent CNB before the surgery were enrolled. A cut-off value of 20% was used for Ki-67-positive criteria. Expression of estrogen receptor (ER), progesterone receptor (PgR), and HER2 were examined and compared with that of Ki-67. To evaluate discordance between the pathologists’ earlier assessments, we re-examined Ki-67 expression among the Ki-67 discordant group in a central laboratory. Results: The concordance rate for Ki-67 expression between the two specimen types was 77.7%, which was significantly lower than that for ER, PgR, and HER2 expression (95.9%, 88.1%, and 91.6%, respectively). The concordance rate for re-examined Ki-67 expression among the Ki-67 discordant group improved to 93.8% and was not significantly different from that for the other receptors. Conclusion: The concordance rate for Ki-67 expression between biopsy and surgical specimens was significantly lower than that for ER, PgR, and HER2 expressions, but re-examination of Ki-67 expression in a central laboratory revealed no significant difference among the receptors, suggesting the need for standard pathological assessment of Ki-67 expression for clinical use as a predictive marker of breast cancer.

关键词： Ki-67 CNB Concordance Rate Standard Assessment

Standardized Assessment of Ki-67 in Breast Cancer Patients Using Virtual Slides and an Automated Analyzer in Comparison to Central/Local Pathological Assessments

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Journal of Cancer Therapy 2014年第2期5卷 141-146页

作者： Yoshio Mizuno Hiromi Fuchikami Tsuneo Natori Naoko Takeda Yuko Inoue Junichi Yamada hiroaki abe Hiroshi Seto Kazuhiko Sato Clinical Testing Business Testing Division SRL Inc. Tokyo Japan Department of Breast Oncology Tokyo-West Tokushukai Hospital Tokyo Japan Department of Clinical Pathology Tokyo-West Tokushukai Hospital Tokyo Japan Inoue Ladies Clinic Tokyo Japan Seto Hospital Tokorozawa Japan

Purpose: To standardize the methods to measure Ki-67, there is an interest in automating the assessment of Ki-67. Therefore, we reviewed the possibility of introducing an automated analyzer to standardize the Ki-67 evaluation method. Methods: We retrospectively reviewed a clinical database of patients who underwent surgery for early breast cancer at Tokyo-West Tokushukai Hospital. Among them, those who underwent preoperative core needle biopsy (CNB) were enrolled. The concordance rates of estrogen receptor (ER), progesterone receptor (PgR), human epidermal growth factor receptor 2 (HER2), and Ki-67 by local pathologists were reviewed (valuations made by local pathologists), and nonmatching cases (from August 2008 to October 2011) were reassessed both by central review and using an automated analyzer with virtual slides. The results were compared with the evaluations made by local pathologists, and we reexamined the concordance rate by using central review and the automated analyzer. Results: The concordance rate of Ki-67 evaluations made by local pathologists in the preoperative CNB and surgical specimens was 78.7% in 287 cases pathologically assessed from October 2008 to March 2013. This rate was significantly lower (p < 0.01) than that of ER (95.6%), PgR (88.5%), and HER2 (91.6%). Reassessment of the 37 cases of nonmatching Ki-67 values from 2008 to October 2011 using central review and an automated analyzer resulted in clear improvement in matching of 22 (92.1%) and 24 (93.1%) of 37 cases, respectively. Conclusion: The concordance rate of Ki-67 in preoperative CNB and surgical specimens was lower than that of other biological markers;however, they were nearly equal by reassessment using central review and an automated analyzer.

关键词： Ki-67 Core Needle Biopsy Concordance Rate Virtual Slides Automated Analyzer Standardized Assessment

抽吸获取的脂肪组织中活脂肪细胞、未成活脂肪细胞和其他细胞成分数量的测定

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中国美容整形外科杂志 2011年第7期22卷 I0022-I0023页

作者： Hirotaka Suga Daisuke Matsumoto Keita Inoue Tomokuni Shigeura Hitomi Eto Noriyuki Aoi Harunosuke Kato hiroaki abe Kotaro Yoshimura 魏峰(译) 高景恒(译) 张晨(译) 日本东京东京大学医学院整形外科 Biomaster公司研究所《中国美容整形外科杂志》编辑部大连大学附属新华医院整形外科

背景分析脂肪组织中脂肪细胞和其他细胞成分生存能力和数量的方法仍需进一步评估。方法作者采用抽吸法获得1g脂肪组织，利用离心分离法将脂肪组织分层（顶层、中层和底层），利用烟酸己可碱33342和碘化丙啶为细胞染色，采用二甲氧唑黄... 详细信息

背景分析脂肪组织中脂肪细胞和其他细胞成分生存能力和数量的方法仍需进一步评估。方法作者采用抽吸法获得1g脂肪组织，利用离心分离法将脂肪组织分层（顶层、中层和底层），利用烟酸己可碱33342和碘化丙啶为细胞染色，采用二甲氧唑黄比色法（2，3-bis（2-methoxy-4-nitro-5-sulfophenyl）-5-[（phenyl-amino）carbonyl]-2H-tet-razoliumhydroxide，XTT）和甘油一3．磷酸脱氢酶试验（n=10）评估细胞生存能力和数量。分析配制细胞（脂肪细胞，脂肪基质细胞，和白细胞）数量与XTY和甘油-3-磷酸脱氢酶试验分析结果之间的关联（凡=5）。从相同脂肪组织中分离血管基质部分细胞，并利用多色流式细胞术检测其细胞成分（n=5）。结果烟酸己可碱33342和碘化丙啶染色法将活的脂肪细胞从脂肪粒，死亡脂肪细胞和其他细胞中区分开。作者从1g的抽吸脂肪组织中获得6．9×10^5个未破碎脂肪细胞；原脂肪细胞中有30％发生破碎。XTT和甘油-3-磷酸脱氢酶试验均显示了活脂肪细胞的数量与分析结果之间具有显著相关关系，但是只有甘油-3-磷酸脱氢酶试验结果对脂肪细胞有严格特异性。本研究还发现，脂肪基质细胞与脂肪细胞的比率大于之前研究的描述。结论本研究中单独使用一种或联合使用2种生存能力分析法，均能确定脂肪细胞和其他细胞的数量，但是不采用组织分离而直接评估原始细胞仍有困难。

关键词：脂肪细胞脂肪组织细胞成分抽吸法脂肪基质细胞细胞生存能力多色流式细胞术数

Coexisting Phenomena of Surge and Rotating Stall in an Axial Flow Compressor

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Journal of Thermal Science 2013年第6期22卷 547-554页

作者： Takuya abe hiroaki MITSUI Yutaka OHTA Graduate Student Graduate School of Science and EngineeringWaseda University Department of Applied Mechanics and Aerospace Engineering Waseda University

The unsteady inner flow structure of a single-stage axial flow compressor under the coexisting conditions of surge and rotating stall was experimentally investigated via detailed measurements of the unsteady characteristics and the internal flow velocity fluctuations. The main relevant feature of the tested compressor is a shock tube with a capacity tank connected in series to the compressor outlet through slits and a concentric duplex pipe: surge and rotating stall can both be generated by connecting the shock tube. Research attention is focused on the unsteady behavior of a rotating stall during the surge cycle. The size of the rotating stall cell during the recovery process of an irregular surge cycle was experimentally determined by the circumferential flow velocity fluctuations ahead of the rotor blade. The results suggested that the size of the rotating stall cell at the switching point of the performance curve between large and small cycles is considered to be the key parameter in determining the following surge cycle. In addition, the surge cycle is largely influenced by the unsteady behavior of the rotating stall cell.

关键词： Axial flow compressor Surge Rotating stall Coexisting state of surge and rotating stall

Influence of the safety and diagnostic accuracy of preoperative endoscopic ultrasound-guided fine-needle aspiration for resectable pancreatic cancer on clinical performance

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World Journal of Gastroenterology 2014年第13期20卷 3620-3627页

作者： Taiki Kudo Hiroshi Kawakami Masaki Kuwatani Kazunori Eto Shuhei Kawahata Yoko abe Manabu Onodera Nobuyuki Ehira hiroaki Yamato Shin Haba Kazumichi Kawakubo Naoya Sakamoto Department of Gastroenterology and Hepatology Hokkaido University Graduate School of MedicineSapporo 060-8638Japan

AIM: To evaluate the safety and diagnostic accuracy of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in a cohort of pancreatic cancer patients.

关键词： Pancreatic cancer Diagnosis Biopsy Endoscopic ultrasound-guided fine-needle aspiration Preoperative diagnosis

CO₂ Capture at Room Temperature and Ambient Pressure: Isomer Effect in Room Temperature Ionic Liquid/Propanol Solutions

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Green and Sustainable Chemistry 2016年第2期6卷 116-124页

作者： Hiroshi abe Azusa Takeshita Hirokazu Sudo Koichi Akiyama hiroaki Kishimura Department of Materials Science and Engineering National Defense Academy Yokosuka Japan

A CO2 capture system without supercritical CO2 was optimized for mixtures of hydrophobic room temperature ionic liquids (RTILs) and propanol. We tested RTILs using bis(trifluoromethanesulfonyl)imide, TFSI-, anion and four quaternary ammonium cations, two quaternary phosphonium cations, and one imidazolium cation. The addition of 2-propanol into the RTILs clearly promoted the capture of normal CO2(nCO2) at ambient temperature and pressure. When combined with 2-propanol, the most efficient RTILs for nCO2 capture were N-butyl-N,N,N-trimethylammonium TFSI-. This enhancement of nCO2 capture was not observed in RTIL mixtures with 1-propanol or in propanol mixtures containing other phosphonium- and imidazolium-based RTILs. The torsion angle of TFSI-, which was calculated using density functional theory, is thought to be related to high nCO2 capture efficiently.

关键词： CO2 Capture Room Temperature Ionic Liquids Propanol Isomer Effect Torsion Angle of TFSI- Anion

DEVELOPMENT AND DEMONSTRATION OF ATR-MOX FUEL

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DEVELOPMENT AND DEMONSTRATION OF ATR-MOX FUEL

Feasibility study of laser-driven neutron sources for pharmaceutical applications

第十三届国际核工程大会

作者： Tomoyuki abe Seiichiro Maeda hiroaki Nakazawa Japan Nuclear Cycle Development Institute Japan Nuclear Cycle Development Institute Japan Nuclear Cycle Development Institute

＜正＞ Advanced thermal reactor （ATR） is a heavy-water-moderated, boiling-light-water-cooled, pressure-tube-type reactor developed by Japan Nuclear Cycle Development Institute （JNC）. And the prototype ATR "FUGEN" is the world first thermal neutron power reactor to utilize uranium and plutonium mixed oxide （MOX） fuel practically and the operation of FUGEN ended in 2003 after 25 years of pioneering works. JNC developed MOX fuels for ATR to provide a flexible utilization of plutonium. The

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High Power Laser Science and Engineering 2023年第2期11卷 37-43页

作者： Takato Mori Akifumi Yogo Yasunobu Arikawa Takehito Hayakawa Seyed R.Mirfayzi Zechen Lan Tianyun Wei Yuki abe Mitsuo Nakai Kunioki Mima hiroaki Nishimura Shinsuke Fujioka Ryosuke Kodama Institute of Laser Engineering Osaka UniversitySuitaJapan National Institutes for Quantum Science and Technology TokaiJapan Tokamak Energy Ltd. AbingdonUK Graduate School of Engineering Osaka UniversitySuitaJapan Fukui University of Technology FukuiJapan

We predict the production yield of a medical radioisotope^(67)Cu using^(67)Zn(n,p)^(67)Cu and ^(68)Zn(n,pn)^(67)Cu reactions with fast neutrons provided from laser-driven neutron *** neutrons were generated by the p+9Be and d+9Be reactions with high-energy ions accelerated by laser–plasma *** evaluated the yield to be(3.3±0.5)×10^(5) atoms for^(67)Cu,corresponding to a radioactivity of 1.0±0.2 Bq,for a Zn foil sample with a single laser *** a simulation with this result,we estimated^(67)Cu production with a high-frequency *** result suggests that it is possible to generate^(67)Cu with a radioactivity of 270 MBq using a future laser system with a frequency of 10 Hz and 10,000-s radiation in a hospital.

关键词： laser ion acceleration laser-driven neutron source medical radioisotope