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Cone beam computed tomographic evaluation of pharyngeal airway in North Indian children with different skeletal patterns

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World Journal of Radiology 2021年第2期13卷 40-52页

作者： Anuraj Singh Kochhar Maninder Singh Sidhu Ritasha Bhasin Gulsheen Kaur Kochhar himanshu dadlani Jagpreet Sandhu Bobby Virk Former Orthodontist Max HospitalGurgaon 122001India Department of Orthodontics Faculty of Dental SciencesSGT UniversityGurugram 122001India Faculty of Dentistry University of TorontoToronto M5G 1G6Canada Department of Pediatric and Preventive Dentistry National Dental College and HospitalDerabassi 140507PunjabIndia Department of Periodontology Kalka Dental CollegeUttar Pradesh 210507India Senior Consultant Department of Dental SurgeryMax HospitalGurgaon 122001Indi Formerly at Department of Orthodontics Genesis Institute of Dental SciencesPunjab 152001India Chief Orthodontist Smile With BracesPuyallupWA 98371United States

BACKGROUND In growing patients with skeletal discrepancies,early assessment of functional factors can be vital for the restoration of normal craniofacial *** To compare airway volumes in patients with mandibular retrognathism with the normal anteroposterior skeletal relationship,thereby assessing the association between cephalometric variables and airway *** Cone-beam computed tomography volume scans,and lateral cephalograms,3-dimensional airway volume and cross-sectional areas of 120 healthy children(54 boys and 66 girls mean age 15.19±1.28)which were done for orthodontic assessment were *** subjects were divided into 2 groups based on the angle formed between point A,Nasion and point B(ANB)values and cephalometric variables(such as anterior and posterior facial height,gonial angle etc.)airway volumes,and cross-sectional measurements were compared using independent t ***’s correlation coefficient test was used to detect any relationship of different parts of the airway and between airway volume and 2-dimensional cephalometric *** Means and standard deviations for cephalometric,cross-sectional,and volumetric variables were ***,mandibular body length and facial convexity were statistically highly significant(P<0.01)whereas condylion to point A,nasal airway and total airway volume(P<0.05)were statistically *** nasal airway volume and the superior pharyngeal airway volume had a positive correlation(P<0.01),nasal airway was correlated to middle(P<0.05)and total airway superior had a relation with middle(P<0.05),inferior and total airway(P<0.05),middle was related to all other airways;inferior was also related to all the airways except *** cephalometric values were positively correlated with the airway volume with Frankfurt Mandibular Plane Angle and facial convexity showed significant correlations with total airway volume(P<0.05).Additionally,ANB angle was significantly correlated wit

关键词： Pharyngeal airway Cone beam computed tomography Skeletal pattern Malocclusion Retrognathic Airway volume

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Improved survival at the cost of more chronic lung disease?Current management and outcomes in extremely preterm infants born in New South Wales and the Australian Capital Territory:2010-2020

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World Journal of Pediatrics 2024年第3期20卷 230-238页

作者： Nele Legge himanshu Popat Dominic Fitzgerald Liverpool Hospital Corner Elizabeth and Goulburn StreetsLiverpoolNSWAustralia University of Sydney CamperdownAustralia Children's Hospital Westmead WestmeadAustralia

Background Since 2010,most tertiary care hospitals in Australia have changed how they care for extremely premature ***,in-hospital and longer-term outcome data have suggested unchanged or even worse health outcomes in later epochs,especially respiratory *** study examined the trend in outcomes since these changes were introduced,particularly the prevalence of chronic neonatal lung disease(CLD).Methods This is a retrospective cross-sectional analysis of data from the Neonatal Intensive Care Units'(NICUS)database of all perinatal intensive care units in New South Wales and the Australian Capital Territory,including infants born at≥24 and≤28 weeks of gestational age in tertiary perinatal units between January 1,2010,and December 31,*** trends and changes in primary outcome were examined by linear and adjusted multivariable logistic regression *** This study included 3258 *** saw significant changes in antenatal magnesium sulfate(75% increase),delayed cord clamping(66% increase),delivery room intubations(30% decrease),any time(20% decrease),duration on mechanical ventilation(100-hour decrease),and hours on noninvasive ventilation(200-hour increase).Mortality decreased from 17% to 6%.The incidence of CLD increased significantly even when adjusted for confounders(15% increase).Any time and mean hours spent on mechanical ventilation significantly increased the odds of *** study could not find a significant association of any of the protective antenatal treatments on *** The last decade saw a significant improvement in survival and survival to discharge without major *** was increased use of magnesium sulfate,delayed cord clamping,and less invasive respiratory management of extremely preterm *** avoidance of mechanical ventilation may impact the incidence of CLD.

关键词： Chronic lung disease Extreme prematurity Health outcomes Survival

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Collective wetting transitions of submerged gas-entrapping microtextured surfaces

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Droplet 2024年第3期3卷 102-106页

作者： Sankara Arunachalam himanshu Mishra Environmental Science and Engineering Program Biological and Environmental Sciences and Engineering DivisionKing Abdullah University of Science and Technology(KAUST)ThuwalKingdom of Saudi Arabia Water Desalination and Reuse Center King Abdullah University of Science and Technology(KAUST)ThuwalKingdom of Saudi Arabia

Numerous natural and industrial processes entail the spontaneous entrapment of gas/air as rough/patterned surfaces are submerged under *** the wetting transitions ensue,the gas diffuses into the water leading to the fully water-filled ***,the standard models forwetting do not accountfor the microtexture’s topography on collective wetting *** other words,it is not clear whether the lifetime of n cavities arranged in a one-dimensional(I-D)line or a two-dimensional(II-D)(circular or square)lattice would be the same or not as a single 0-D *** response,we tracked the time-dependentfates of gas pockets trapped in I-D and II-D lattices and compared them with wetting transitions in commensurate 0-D ***,the collective wetting transitions in the I-D and the II-D arrays had a directionality such thatthe gas from the outermost cavities was lostthe first,while the innermost gotfilled by water the *** essence,microtexture’s spatial organization afforded shielding to the loss of the gas from the innermost cavities,which we probed as a function of the microtexture’s pitch,surface density,dimensionality,and hydrostatic *** findings advance our knowledge of wetting transitions in microtextures and inspiring surface textures to protect electronic devices against liquid ingression.

关键词： topography transitions submerged

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Identification of gene classifier and modules associated with SARS-CoV-2 ARI in nasal swab

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Genes & Diseases 2024年第1期11卷 38-41页

作者： Pandikannan Krishnamoorthy Athira S.Raj himanshu Kumar Department of Biological Sciences Laboratory of Immunology and Infectious Disease BiologyIndian Institute of Science Education and Research(llSER)BhopalBhopalMP 462066India Laboratory of Host Defense WPl ImmunologyFrontier ResearchCentreOsakaUniversityOsaka 5650871Japan

During a sudden viral pandemic,where the pathogenesis and nature of the infection are unclear,early and accurate identification of the patients infected with the pandemiccausing pathogen is crucial to prevent excess *** the coronavirus disease 2019(COvID-19)pandemic,early diagnosis of severe acute respiratory syndrome virus-2(SARS-CoV-2)is limited by the incidence of the symptoms that are shared with acute respiratory illnesses(ARl)caused by other pathogens.

关键词： acute diagnosis respiratory

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Dengue causing relapse of minimal change disease: A double-edged sword

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Asian Pacific Journal of Tropical Medicine 2024年第5期17卷 237-238页

作者： Sourabh Sharma himanshu Verma Sanjay Kalra Department of Nephrology VMMC&Safdarjung HospitalNew DelhiIndia Department of Endocrinology Bharti HospitalKarnalIndia

Dengue virus infection is endemic in India with seasonal *** can lead to lethal consequences with plasma leakage and/or bleeding[1,2].Dengue shock syndrome has high mortality in developing countries like *** can cause functional proteinuria and even heavy proteinuria[3-6].Though dengue has been implicated to cause glomerulonephritis[7],to the best of our knowledge,dengue as a cause of relapse of minimal change disease(MCD)has not been reported.

关键词： relapse mortality bleeding

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Charting the course:India's health expenditure projections for 2035

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Global Health Journal 2024年第2期8卷 58-66页

作者： Pragyan Monalisa Sahoo himanshu Sekhar Rout Department of Analytical&Applied Economics Utkal UniversityBhubaneswarOdishaIndia Department of Analytical and Applied Economics&RUSA Centre of Excellence in Public Policy and Governance Utkal UniversityVani ViharBhubaneswarOdishaIndia

Objectives Understanding past trends and forecasting future changes in health spending is vital for planning and reducing reliance on out-of-pocket(OOP)*** current study analyzed health expenditure patterns in India and forecasted future trends and patterns until *** Data on health expenditure in India from 2000 to 2019 was collected from the Organisation for Economic Co-operation and Development(OECD)iLibrary and National Health Accounts 2019 *** domestic product(GDP)data from the World Bank was also *** statistics analyzed the composition and pattern,while the exponential smoothing model forecasted future health *** The findings revealed that expenditure made by OOP is the primary health financing source,followed by government and pre-paid private *** percentage of GDP allocated to total health expenditure remains stable,while the per capita health expenditure *** in expenditure among states are observed,with Karnataka relying heavily on pre-paid private *** projections suggest a decline in per capita and total health expenditure as a share of GDP,with a slight increase in the government’s ***-paid private expenditure per capita and OOP health expenditure as a share of the total is projected to remain relatively constant but still high in absolute *** The study highlights variations in health spending in India,characterized by high OOP spending,limited public coverage,and a need for investments,and reforms to improve healthcare access and equity.

关键词： Health expenditure Health spending Health financing Forecasting Exponential smoothing India

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Recombinant vaccines:Current updates and future prospects

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Asian Pacific Journal of Tropical Medicine 2024年第8期17卷 338-350页

作者： Vivek Kumar Anuj Verma Riddhi Singh Priyanshi Garg Santosh Kumar Sharma himanshu Narayan Singh Santosh Kumar Mishra Sanjay Kumar Department of Allied Medical Sciences School of Allied Medical SciencesLovely Professional UniversityPhagwaraPunjabIndia Bioengineering Division of Department of Bioscience and Biomedical EngineeringIndian Institute of Technology BhilaiChhattisgarhIndia Department of Biotechnology IMS Engineering CollegeGhaziabadU.P.India Department of Chemistry and Biochemistry University of WindsorOntario N9B3P4Canada Biological and Biocomputational Laboratory Department of Life SciencesSharda School of Basic Sciences and ResearchSharda UniversityGreater NoidaU.P.India Department of System Biology Columbia University Irving Medical CenterNew YorkNY 10032USA Department of Life Sciences Sharda School of Basic Sciences and ResearchSharda UniversityGreater NoidaU.P.India

Recombinant technology-based vaccines have emerged as a highly effective way to prevent a wide range of *** technology improved vaccine manufacturing,rendering it more efficient and *** vaccines have multiple advantages compared to conventional *** pandemic has heightened awareness of the advantages of these vaccine technologies;trust and acceptance of these vaccines are steadily growing *** work offers an overview of the prospects and advantages associated with recombinant ***,it discusses some of the challenges likely to arise in the *** ability to target diverse pathogen classes underscores their contributions to preventing previously untreatable diseases(especially vector-borne and emerging diseases)and hurdles faced throughout the vaccine development process,especially in enhancing the effectiveness of these ***,their compatibility with emerging vaccination platforms of the future like virus-like particles and CRISPR/Cas9 for the production of next-generation vaccines may offer many *** review also reviewed the hurdles faced throughout the vaccine development process,especially in enhancing the effectiveness of these vaccines against vector-borne diseases,emerging diseases,and untreatable diseases with high mortality rates like AIDS as well as cancer.

关键词： Malaria Dengue Emerging diseases Immunoinformatics Virus-like particles CRISPR-Cas9

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Identification of optimal composition with superior electrochemical properties along the zero Mn^(3+)line in Na_(0.75)(Mn-Al-Ni)O_(2)pseudo ternary system

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Journal of Energy Chemistry 2024年第9期96卷 206-216页

作者： Hari Narayanan Vasavan Manish Badole Samriddhi Saxena Velaga Srihari Asish Kumar Das Pratiksha Gami Neha Dagar Sonia Deswal Pradeep Kumar himanshu Kumar Poswal Sunil Kumar Department of Metallurgical Engineering and Materials Science Indian Institute of Technology IndoreSimrol 453552India High Pressure&Synchrotron Radiation Physics Division Bhabha Atomic Research Centre400085 MumbaiIndia School of Physical Sciences Indian Institute of Technology MandiHimachal Pradesh 175005India Center for Electric Vehicle and Intelligent Transport Systems Indian Institute of Technology IndoreSimrol 453552India

Biphasic layered oxide cathodes,known for their superior electrochemical performance,are prime candidates for commercializing in Na-ion ***,we unveil a series of P3/P2 monophasic and biphasic Al-substituted Na_(3/4)Mn_(5-x/8)Al_(2x/8)Ni_(3-x/8)O_(2)layered oxide cathodes that lie along the‘zero Mn^(3+)line’in the Na_(3/4)(Mn-Al-Ni)O_(2)pseudo-ternary *** structural analysis showed a larger Na^(+)conduction bottleneck area in both P3 and P2 structures with a higher Al3+content,which enhanced their rate *** each composition,the P3/P2 biphasic compound with nearly equal fractions of P3 and P2 phases outperformed their monophasic counterparts in almost all electrochemical performance *** synchrotron XRD measurements obtained for the monophasic P3 and biphasic P2/P3 samples revealed the absence of the O3 phase during *** high structure stability and faster Na^(+)transport kinetics in the biphasic samples underpins the enhancement of electrochemical properties in the Al-substituted P3/P2 *** results highlight fixed oxidation state lines as a novel tool to identify and design layered oxide cathodes for Na-ion batteries in pseudo-ternary diagrams involving Jahn-Teller active cations.

关键词： Layered oxides Biphasic cathode Operando Synchrotron XRD Electrochemical behavior Cyclic performance

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Tuberculosis in kidney transplant candidates and recipients

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World Journal of Transplantation 2024年第3期14卷 59-69页

作者： Pallavi Prasad Sourabh Sharma Subashri Mohanasundaram Anupam Agarwal himanshu Verma Department of Nephrology Vardhman Mahavir Medical College and Safdarjung HospitalNew Delhi 110029DelhiIndia Department of Nephrology Prashanth HospitalChennai 600042Tamil NāduIndia

Tuberculosis(TB)is the leading cause of infectious mortality and morbidity in the world,second only to coronavirus disease *** with chronic kidney disease and kidney transplant recipients are at a higher risk of developing TB than the general *** TB is difficult to diagnose in this population due to close *** transplant candidates should be screened for latent TB infection and given TB *** who develop active TB pre-or post-trans-plantation should receive multidrug combination therapy of antitubercular therapy for the recommended duration with optimal dose modification as per glomerular filtration rate.

关键词： Tuberculosis Latent Antitubercular therapy Kidney transplantation Donor Interferon-gamma release assays Tuberculin Rifampicin Isoniazid

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Renal resistive index measurements by ultrasound in patients with liver cirrhosis:Magnitude and associations with renal dysfunction

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World Journal of Radiology 2024年第6期16卷 221-231页

作者： himanshu Surya Ramesh Kumar Rajeev Nayan Priyadarshi Sabbu Surya Prakash Sudhir Kumar Department of Gastroenterology All India Institute of Medical SciencesPatna 801507India Department of Radiodiagnosis All India Institute of Medical SciencesPatna 801507India

BACKGROUND The hemodynamic alterations seen in liver cirrhosis lead to renal vasoconstriction,ultimately causing acute kidney injury(AKI).The renal resistive index(RRI)is the most common Doppler ultrasound variable for measuring intrarenal vascular *** To evaluate the association of the RRI with AKI in patients with liver cirrhosis and to identify risk factors for high *** This was a prospective observational study,where RRI was measured using Doppler ultrasound in 200 consecutive hospitalized patients with *** association of RRI with AKI was *** receiver operating characteristic(ROC)curve analysis was utilized to determine discriminatory cut-offs of RRI for various AKI *** analysis was conducted to determine the predictors of high *** The mean patient age was 49.08±11.68 years,with the majority(79.5%)being male;the predominant etiology of cirrhosis was alcohol(39%).The mean RRI for the study cohort was 0.68±0.09,showing a progressive increase with higher Child-Pugh class of ***,AKI was present in 129(64.5%)*** mean RRI was significantly higher in patients with AKI compared to those without it(0.72±0.06 vs 0.60±0.08;P<0.001).A total of 82 patients(41%)had hepatorenal syndrome(HRS)-AKI,29(22.4%)had prerenal AKI(PRA),and 18(13.9%)had acute tubular necrosis(ATN)-*** mean RRI was significantly higher in the ATN-AKI(0.80±0.02)and HRS-AKI(0.73±0.03)groups than in the PRA(0.63±0.07)and non-AKI(0.60±0.07)*** demonstrated excellent discriminatory ability in distinguishing ATN-AKI from non-ATN-AKI(area under ROC curve:93.9%).AKI emerged as an independent predictor of high RRI(adjusted odds ratio[OR]:11.52),and high RRI independently predicted mortality among AKI patients(adjusted OR:3.18).CONCLUSION In cirrhosis patients,RRI exhibited a significant association with AKI,effectively differentiated between AKI phenotypes,and predicted AKI mortality.

关键词： Renal resistive index Cirrhosis Acute kidney injury Hepatorenal syndrome Renal Doppler

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