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National trends in resection of the distal pancreas

World journal of Gastroenterology 2012年第32期18卷 4342-4349页

作者： Armando Rosales-Velderrain Steven P Bowers Ross F goldberg Tatyan M Clarke Mauricia A Buchanan john A Stauffer Horacio j Asbun Department of General Surgery Mayo Clinic FloridaJacksonvilleFL 32225United States

AIM:To investigate national trends in distal pancreatectomy(DP) through query of three national patient care ***:From the Nationwide Inpatient Sample(NIS,2003-2009),the National Surgical Quality Improvement Project(NSQIP,2005-2010),and the Surveillance Epidemiology and End Results(SEER,2003-2009) databases using appropriate diagnostic and procedural codes we identified all patients with a diagnosis of a benign or malignant lesion of the body and/or tail of the pancreas that had undergone a partial or distal *** of laparoscopy was defined in NIS by the International Classification of Diseases,Ninth Revision correspondent procedure code;and in NSQIP by the exploratory laparoscopy or unlisted procedure current procedural terminology *** SEER,patients were identified by the International Classification of Diseases for Oncology,Third Edition diagnosis codes and the SEER Program Code Manual,third edition procedure *** analyzed the databases with respect to trends of inpatient outcome metrics,oncologic outcomes,and hospital volumes in patients with lesions of the neck and body of the pancreas that underwent operative ***:NIS,NSQIP and SEER identified 4242,2681 and 11 082 DP resections,***,laparoscopy was utilized in 15%(NIS) and 27%(NSQIP).No significant increase was seen over the course of the *** was performed for malignancy in 59%(NIS) and 66%(NSQIP).Neither patient Body mass index nor comorbidities were associated with operative approach(P = 0.95 and P = 0.96,respectively).Mortality(3% vs 2%,P = 0.05) and reoperation(4% vs 4%,P = 1.0) was not different between laparoscopy and open *** complications(10% vs 15%,P < 0.001),hospital costs [44 741 dollars,interquartile range(IQR) 28 347-74 114 dollars vs 49 792 dollars,IQR 13 299-73 463,P = 0.02] and hospital length of stay(7 d,IQR 4-11 d vs 7 d,IQR 6-10,P < 0.001) were less when laparoscopy was *** and two year sur

关键词： Laparoscopic distal pancreatectomy Trends Nationwide Inpatient Sample National Surgical Quality Improvement Project Surveillance epidemiology and end results

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A meta-analysis of 1-year outcomes of transcatheter versus surgical aortic valve replacement in low-risk patients with severe aortic stenosis

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journal of Geriatric Cardiology 2020年第1期17卷 43-50,I0008-I0010页

作者： Aaqib H Malik Syed Zaid Hasan Ahmad joshua goldberg Tanya Dutta Cenap Undemir Martin Cohen Wilbert S Aronow Steven L Lansman Department of Medicine Westchester Medical Center and New York Medical CollegeValhallaNYUSA Department of Cardiology Westchester Medical Center and New York Medical CollegeValhallaNYUSA Section of Cardiothoracic Surgery Department of SurgeryWestchester Medical CenterValhallaNew YorkUSA

Background Transcatheter aortic valve replacement(TAVR)for the treatment symptomatic severe aortic stenosis(AS)is indicated in patients with intermediate or higher surgical *** trials showed TAVR,and surgical aortic valve replacement(SAVR)perform similarly at 1-year for the composite outcomes of mortality,stroke and *** performed a comprehensive meta-analysis to compare individual outcomes at 1-year for TAVR compared to SAVR in low-risk *** Pub Med,Embase,and Cochrane central were searched for all the randomized controlled trials(RCTs)that reported 1-year comparative outcomes of TAVR and surgical aortic valve replacement(SAVR).Our conclusions are based upon the random-effects model using Der Simonian-Laird *** Data from 4 trials and 2887 randomized patients showed that TAVR had lower rates of all-cause mortality,cardiovascular mortality,and atrial fibrillation compared to SAVR at 1-year follow-up(P<0.05 for all).Also,TAVR was also associated with a significantly higher risk of permanent pacemaker implantation and moderate-severe paravalvular leak(P<0.05).Conclusions The latest randomised trial data demonstrates that in short-term,TAVR is safe and effective in reducing all-cause mortality or *** follow-up of RCTs is needed to determine the durability of clinical benefits in TAVR over SAVR in low-risk patients.

关键词： Aortic stenosis Low surgical risk Meta-analysis Transcatheter aortic valve replacement

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Retrograde intrarenal surgery for lower pole stones utilizing stone displacement technique yields excellent results

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Asian journal of Urology 2023年第1期10卷 58-63页

作者： Dor Golomb Hanan goldberg Shlomi Tapiero Yariv Stabholz Paz Lotan Abd Elhalim Darawsha Ronen Holland Yaron Ehrlich David Lifshitz Department of Urology Rabin Medical Center-Beilinson HospitalPetach TikvaSackler Faculty of MedicineTel Aviv UniversityTel AvivIsrael Department of Urology State University of New York Upstate Medical UniversitySyracuseNYUSA

Objective:To evaluate the long-term stone-free rate(SFR)of retrograde intrarenal surgery(RIRS)in the treatment of lower pole renal calculi using only basket relocation and identify independent predictors of stone-free ***:All consecutive patients undergoing RIRS lower pole renal calculi at a single highvolume tertiary center were analyzed *** pole stones were relocated to the upper pole,where laser lithotripsy was *** patients were followed up in the clinic following the surgery and yearly *** stone-free status was assessed with a combination of an abdominal ultrasound and abdominal X-ray,or an abdominal non-contrast computed tomography if the stones were known to be ***:A total of 480 consecutive patients who underwent RIRS for treatment of lower pole renal calculi,between january 2012 and December 2018,were analyzed from a prospectively maintained database of 3000 *** a median follow-up time of 18.6 months,the mean SFR was 94.8%.The procedures were unsuccessful in 26(5.4%)patients due to unreachable *** median stone size of the unreachable stones was 12 mm(range 10e30 mm).Multivariable logistic regression analysis revealed two predictors of SFR for lower pole stones:a small cumulative stone burden(odds ratio[OR]:0.903,95%confidence interval[CI]:0.867e0.941,p<0.0001)and preoperative ureteral stent insertion(OR:0.515,95%CI:0.318e0.835,pZ0.007).Conclusion:The long-term SFR of RIRS for the treatment of lower pole stones with basket displacement with appropriate patient selection is high.

关键词： Ureteroscopy Lower pole stones Retrograde intrarenal surgery Stone-free rate Basketing

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Nogo在神经再生中的作用

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神经解剖学杂志 2000年第2期16卷 189-190页

作者： goldberg jL and BarresBA DepartmentofNeurobiology

体内大部分组织如肌肉、皮肤、肝脏和外周神经,损伤后均有很强的再生能力.然而,中枢神经系统(CNS)几乎没有这种能力,损伤后的轴突及神经元不能再生.导致损伤后功能迟迟得不到恢复,如脊髓损伤导致的瘫痪.

关键词：中枢神经系统抑制性蛋白 Nogo基因神经再生

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Paul Klee, 1879-1940

Paul Klee, 1879-1940

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作者： (author.)Partsch Susanna (artist..1879-1940 )Klee Paul (translator.)Schmitt-Thomas hilary

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贵州瓮安陡山沱组剖面碳同位素生物地球化学研究

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矿物岩石 2005年第2期25卷 75-80页

作者：郭庆军刘丛强 Harald Strauss Tatiana goldberg 杨卫东中国科学院地球化学研究所环境地球化学国家重点实验室 Geologisch-Palontologisches Institut Universitt MünsterCorrensstrasse 2448149 MünsterGermany

　在对扬子地台贵州瓮安陡山沱组剖面干酪根碳同位素组成进行分析后发现其变化显示了一定的规律性。碳同位素规律变化反映了最初的沉积信息,特别是有机质埋藏量的变化。获得的陡山沱期沉积岩中碳同位素组成研究结果初步反映了震旦-寒武... 详细信息

　在对扬子地台贵州瓮安陡山沱组剖面干酪根碳同位素组成进行分析后发现其变化显示了一定的规律性。碳同位素规律变化反映了最初的沉积信息,特别是有机质埋藏量的变化。获得的陡山沱期沉积岩中碳同位素组成研究结果初步反映了震旦-寒武交变期沉积环境的面貌;碳同位素组成变化规律可以用于反映扬子地台沉积层序和世界同期地层全球碳循环的对比和参考。为扬子区陡山沱期环境变化和生物演化提供了证据。δ13Cker值在-32.3‰和-24.5‰(PDB)间漂移与δ13Ccarb值在-4.9‰和3.6‰(PDB)间的变化,反映了当时海水的碳同位素组成。无机和有机碳同位素组成之差的Δδorg-carb值沿剖面不断变化,是由于沉积有机质中有促进发酵功能的细菌数量比例变化所致。

关键词：瓮安震旦-寒武交变期陡山沱组瓮安生物群成磷事件碳酸盐岩和干酪根碳同位素组成

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An Essential Oil Blend Decreases Methane Emissions and Increases Milk Yield in Dairy Cows

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Open journal of Animal Sciences 2019年第3期9卷 259-267页

作者： Kenton j. Hart Hefin G. jones Kate E. Waddams hilary j. Worgan Beatrice Zweifel C. jamie Newbold Institute of Biological Environmental and Rural Sciences (IBERS) Aberystwyth University Aberystwyth Ceredigion UK Caltech Crystalyx Siloth Cumbria UK Agolin SA Switzerland Scotland’s Rural College Kings Buildings Edinburgh UK

This study was conducted to investigate the effect of a commercial essential oil (EO) additive on milk production and methane (CH4) emissions from dairy cows. Early lactation Holstein-Friesian dairy cows were fed grass, whole crop wheat and corn silage total mixed ration. Cows were allocated to one of two experimental treatments: Control (no additive, CON) or 1 g/head/day of EO. Cows were housed in a free stall barn, split into two pens for the duration of the experiment. Two gas data loggers units used to measure CH4 emissions were provided per pen for the duration of the 22 week-long study. Milk yield was determined daily, and milk components were analyzed every two weeks. CH4 was recorded continuously, and daily values were tabulated. Body weight and body condition score were determined at the start and bi-weekly. Results were analyzed as a randomized complete block trial. In total, 149 cows participated in the study (76 CON, 73 EO). Milk yields were greater (P 0.05) by treatment. Yields of fat, protein, lactose, and solids were higher for EO fed cows (P 4 output was reduced with the EO compared to the CON treatment (411 g/day vs 438 g/day;13.8 g/L of milk vs 17.2 g/L of milk, P < 0.05) over the duration of the trial. There were no effects of treatment on reproductive performance or the occurrence of mastitis. Feeding EO to dairy cows reduced CH4 emissions whilst also increasing performance.

关键词： Dairy Cows Essential Oils Methane Milk Yield

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Angiographic and clinical outcomes in elderly subjects treated with percutaneous coronary intervention following fibrinolytic administration for ST-elevation myocardial infarction

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journal of Geriatric Cardiology 2005年第1期2卷 10-14页

作者： Ajay j.Kirtane Adam H.Skolnick hilary Oman Christopher Ruisi Leida Perez Nicole Kraimer Dimitrios Karmpaliotis Duane S.Pinto Eugene Braunwald C.Michael Gibson Cardiovascular Division Department of Medicine Beth Israel Deaconess Medical Center and Harvard Medical SchoolBostonMAUSA TIMI Study Group Cardiovascular Division Department of MedicineBrighton and Women's HospitalBostonMAUSA TIMI Study Group Cardiovascular Division Department of MedicineBrigham and Women's HospitalBostonMAUSA

Background Prior studies have demonstrated that the achievement of faster coronary artery flow following reperfusion therapies is associated with improved outcomes among ST-elevation myocardial infarction (STEMI) patients. The association of patient age with angiographic characteristics of flow and perfusion after rescue/adjunctive percutaneous coronary intervention (PCI) following the administration of fibrinolytic therapy has not been previously investigated. Objectives and Methods We examined the association between age (≥ 70 years or ＜ 70years)and clinical and angiographic outcomes in 1472 STEMI patients who underwent rescue/adjunctive PCI following fibrinolytic therapy in 7 TIMI trials. We hypothesized that elderly patients would have slower post-PCI epicardial flow and worsened outcomes compared to younger patients. Results The 218 patients aged ≥ 70 years (14.8%) had more comorbidities than younger patients. Although these patients had significant angiographic improvement in TIMI frame counts and rates of TIMI Grade 3 flow following rescue/adjunctive PCI, elderly patients had higher (slower)post-PCI TIMI frame counts compared to the younger cohort (25 vs 22 frames, P = 0.039), and less often achieved post-PCI TIMI Grade 3 flow (80.1 vs 86.4%, P = 0.017). The association between age ( ≥70 years) and slower post-PCI flow was independent of gender, time to treatment, left anterior descending (LAD) lesion location, and pulse and blood pressure on admission. Elderly patients also had 4-fold higher mortality at 30 days (12.0 vs 2.7%,P = 0. 001 ). Conclusions This study suggests one possible mechanism underlying worsened outcomes among elderly STEMI patients insofar as advanced chronological age was associated with higher TIMI frame counts and less frequent TIMI Grade 3 flow after rescue/adjunctive PCI.

关键词： TIMI flow grade TIMI frame count percutaneous coronary intervention age elderly

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Hospital healthcare costs attributable to heat and future estimations in the context of climate change in Perth, Western Australia

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Advances in Climate Change Research 2021年第5期12卷 638-648页

作者： Michael Xiaoliang TONG Berhanu Yazew WONDMAGEGN Susan WILLIAMS Alana HANSEN Keith DEAR Dino PISANIELLO jianjun XIANG jianguo XIAO Le jIAN Ben SCALLEY Monika NITSCHKE john NAIRN hilary BAMBRICK jonathan KARNON Peng BI School of Public Health The University of AdelaideAdelaideSouth Australia5005Australia Department of Health Western Australia6004Australia Department of Health South Australia5000Australia Australian Bureau of Meteorology Adelaide5000Australia School of Public Health and Social Work Queensland University of TechnologyBrisbaneQueensland4000Australia College of Medicine and Public Health Flinders UniversityBedford ParkSouth Australia5001Australia

Climate change with increasing temperature is making a significant impact on human health, including more heat-related diseases, and increasing the burden on the healthcare system. Although many studies have explored the association between increasing temperatures and negative health outcomes, research on the associated costs of heat-related diseases remains relatively sparse. Furthermore, estimations of future costs associated with heat-attributable hospital healthcare have not been well explored. This study used a distributed lag nonlinear model to estimate heat-attributable hospital healthcare costs in Perth, Western Australia. Using 2006–2012 as the baseline, future costings for 2026–2032 and 2046–2052 were estimated under RCP2.6, RCP4.5, and RCP8.5. Higher temperatures were found to be associated with increased hospital healthcare costs. The total hospital costs attributable to heat over the baseline period 2006–2012 was estimated to be 79.5 million AUD, with costs for mental health hospitalizations being the largest contributor of the heat-related conditions examined. Costs are estimated to increase substantially to 125.8–129.1 million AUD in 2026–2032, and 174.1–190.3 million AUD by midcentury under climate change scenarios. Our findings of a notable burden of heat-attributable healthcare costs now and in the future emphasize the importance of climate change adaptation measures to reduce the adverse health effects of increasing temperatures and heat exposure on the people of Perth.

关键词： Heat-attributable disease Hospital healthcare cost Climate change Perth Australia

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太阳·天气·气候第1版

太阳·天气·气候

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1984年

作者：（美）j.R.Herman （美）R.A.goldberg 盛承禹等译

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