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International Journal of Ophthalmology(English edition) 2020年第7期13卷 1167-1169页

作者： Satoru Kase Shinki Chin Teruhiko Hamanaka Yasuhiro Shinmei Takeshi Ohguchi Susumu ishida Department of Ophthalmology Faculty of Medicine and Graduate School of MedicineHokkaido UniversitySapporo CityHokkaido 060-8638Japan Department of Ophthalmology Japan Red Cross Medical CenterTokyo 150-8935Japan

Dear Editor,I am *** Kase,from the Department of Ophthalmology,Faculty of Medicine and Graduate School of Medicine,Hokkaido University.I write to present the case of clinicopathological findings in Axenfeld-Rieger syn... 详细信息

关键词： Medicine Rieger congenital

Environmental agricultural policy in Japan in harmony with WTO agricultural agreements:current situation and its development (I)

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Agricultural Science & Technology 2004年第4期5卷 2-5页

作者： Masaaki ishida Faculty of Bioresources Mie UniversityJapan

Introduction'Agriculture' could be defined as the human activity of obtaining a larger volume of food and raw materials from a limited land area in order to sustain a growing population. To accomplish this, humans must transform an ecological system of nature into a partly man-made ecological system of arable land. In this ecological system of arable land, crops that require human assistance are predominant, and any other wild species are generally considered undesirable, and so are removed. There are significantly fewer species in an ecological system of arable land than in an ecological system of nature, and the interrelationship among species is weaker. Given these facts,agriculture is in effect accompanied by the destruction of nature, and cannot be said to contribute to the protection of the environment.

关键词：世界贸易组织日本农业环境政策农业协定发展态势

Strength of plastic with various helical wheels meshed types of worms

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材料与冶金学报 2015年第3期14卷 232-235,238页

作者： Makoto Nomura Takao Koide Akio Ueda Yusuke ishida Atsutaka Tamura Tottori University 4 - 101 Minami Koyama - cho Tottori 680 - 8552 Japan Amtec INC. BayTower 2510 1-2-1 Minato-ku Benten Osaka 552-0007 Japan

One-day seminar for residents for implementing abdominal pocketsized ultrasound

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World Journal of Methodology 2021年第4期11卷 208-221页

作者： Hiroko Naganuma Hideaki ishida Department of Gastroenterology Yokote Municipal HospitalYokote 0138602AkitaJapan Department of Gastroenterology Akita Red Cross HospitalAkita-City 010-1495Japan

Despite its proven high utility,integration of pocked-sized portable ultrasound(US)into internal medicine residency training remains *** 10 years,we have held a 1-d seminar biannually,consisting of lecture(half-day)and handson training(half-day)on pocket-sized US of the abdomen and *** lecture consists of training on US physics and clinical applications of pocket-sized US,followed by a lecture covering the basic anatomy of the abdomen and lungs and introducing the systemic scanning *** the simple structure of pocketsized US devices,understanding the basic physics is sufficient yet necessary to operate the pocket-sized US *** is important to understand the selection of probes,adjustment of B mode gain,adjustment of color gain,and acoustic *** comprehension may have a significant positive impact on the overall utilization of pocket-sized US *** easiest and most reliable way to observe the whole abdomen and lungs is a combination of transverse,sagittal,and oblique scanning,pursuing the main vascular system from the center to the periphery of the organ in the abdomen and systemic scanning of the *** is usually a marked change in knowledge and attitudes among the program participants,although skill gaps remain among *** discuss the limitations and problems to this education system as well.

关键词： Pocket-sized ultrasound Abdomen Lung Medical education Resident Ultrasound physics

Two cases of adenocarcinoma occurring in sporadic fundic gland polyps observed by magnifying endoscopy with narrow band imaging

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World Journal of Gastroenterology 2016年第40期22卷 9028-9034页

作者： Kazumi Togo Tetsuya Ueo Hirotoshi Yonemasu Hideho Honda Tetsuya ishida Hiroshi Tanabe Kenshi Yao Akinori Iwashita Kazunari Murakami Departments of Gastroenterology Oita Red Cross Hospital Departments of Pathology Oita Red Cross Hospital Department of Pathology Fukuoka University Chikushi Hospital Department of Endoscopy Fukuoka University Chikushi Hospital Department of Gastroenterology Faculty of Medicine Oita University

Gastric fundic gland polyps(FGPs) are common nonadenomatous gastric polyps arising from normal fundic mucosa without Helicobacter pylori(H. pylori) infection. Although systemic FGPs associated with familial adenomatous polyposis(FAP) often have dysplasia, there are few reports of dysplasia occurring in sporadic F G P s, e s p e c i a l l y w h e n d e t e c t e d b y m a g n i f y i n g endoscopy with narrow band imaging(ME-NBI). We experienced two cases of adenocarcinoma occurring in sporadic FGPs, and their ME-NBI findings were very useful for differentiating FGP with cancer from nondysplastic FGP. A 68-year-old man and a 63-year-old woman were referred to our institution for medical checkup. H. pylori was negative in both patients. Endoscopic examination revealed a small reddishpolypoid lesion on the anterior wall of the upper gastric body and several FGPs. ME-NBI showed an irregular microvascular architecture composed of closed loop- or open loop-type vascular components, plus an irregular microsurface structure composed of oval-type surface components which was different from that of FGPs. FAP was denied because of the absence of colon polyps and no familial history of FAP. Pathological diagnosis was adenocarcinoma occurring in sporadic FGP.

关键词：分散的类型腺癌与狭窄的乐队成像放大内视镜检查法没有 Helicobacter pylori 感染的腺癌 Fundic 腺息肉

Nurse-led group cognitive behavioral therapy for major depressive disorder among adults in Japan: A preliminary single-group study

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International Journal of Nursing Sciences 2018年第3期5卷 218-222页

作者： Hiroki Tanoue Naoki Yoshinaga Sayaka Kato Keiko Naono-Nagatomo Yasushi ishida Yuko Shiraishi Department of Psychiatric and Mental Health Nursing School of NursingFaculty of MedicineUniversity of MiyazakiJapan Organization for Promotion of Tenure Track University of MiyazakiJapan Center for the Support and Development of Medical Professionals Faculty of MedicineUniversity of MiyazakiJapan Department of Psychiatry Faculty of MedicineUniversity of MiyazakiJapan Department of Psychiatric and Mental Health Nursing Faculty of NursingInternational University of Health and WelfareFukuokaJapan

Objectives:The prevalence and burden of disease of depression necessitates effective and accessible treatment options *** April 2016,Japanese national health insurance has covered nurseadministered cognitive behavioral therapy(CBT)for mood ***,empirical support for nurse-led CBT for depression in Asian countries,especially in Japan,is still *** preliminary study aimed to examine the feasibility and acceptability of nurse-led group CBT for Japanese patients with ***:In this single-arm study,we evaluated the effects of a 6-week group CBT,led by trained nurses,on patients with major *** primary outcome was the Beck Depression Inventory-Ⅱ(BDI-Ⅱ).Assessments were conducted at the beginning and end of the ***:Of 25 participants screened,23 were eligible for the study(of these,three dropped out during the trial but were included in the analysis).Nurse-led group CBT led to significant improvements in the severity of depression(BDI-Ⅱ,P<0.001).The mean total BDI-Ⅱscore improved from 23.1(SD=7.56)to 12.4(SD=8.57),and the pre-to post-effect size was large(Cohen's d=1.33).After CBT,45%of the participants were judged to be treatment responders,and 34%met the remission ***:Our preliminary findings indicate that 6 weeks of nurse-led group CBT produced a favorable treatment outcome for individuals with major depression in a Japanese clinical *** results of this study might encourage more Asian nurses to provide CBT as a part of their nursing *** controlled trials that address the limitations of this study are required.

关键词： Behavior therapy Cognitive therapy Depressive disorder Group psychotherapy Nursing care

Left hepatic trisectionectomy for perihilar cholangiocarcinoma with a right-sided round ligament:A case report

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World Journal of Gastrointestinal Surgery 2020年第2期12卷 68-76页

作者： Tomoyuki ishida Satoshi Nara Keiichi Akahoshi Takeshi Takamoto Yoji Kishi Minoru Esaki Nobuyoshi Hiraoka Kazuaki Shimada Department of Hepatobiliary and Pancreatic Surgery National CancerCenter HospitalTokyo 104-0045Japan Department of Pathology and Clinical Laboratories National Cancer Center HospitalTokyo 104-0045Japan

BACKGROUND A right-sided round ligament(RSRL)is a rare,congenital anomaly of the intrahepatic portal vein,with a reported frequency of 0.2%-1.2%.For patients with perihilar cholangiocarcinoma associated with an RSRL,an accurate understanding of the vascular and biliary anatomy is *** SUMMARY We report a 70-year-old male with perihilar cholangiocarcinoma associated with an *** percutaneous transhepatic embolization of the left and anterior portal branches,we conducted a left trisectionectomy of the liver with extrahepatic bile duct resection and *** postoperative course was uneventful,and R0 resection was *** the liver volume of each section was compared between 7 patients with an RSRL and 20 patients with normal portal vein anatomy,the posterior section in RSRL patients was significantly larger than that in patients with normal portal vein anatomy(median:457 mL vs 306 mL,P=0.031).In patients with perihilar cholangiocarcinoma associated with an RSRL,left trisectionectomy has several surgical advantages:(1)The posterior branch of the portal vein often ramifies independently,and the division of the portal vein is easily conducted;(2)A relatively large amount of remnant liver can be retained;and(3)The anatomy of the posterior branch of the Glissonian pedicle is similar to that in patients with normal *** In patients with an RSRL and perihilar cholangiocarcinoma that does not involve the posterior section,left trisectionectomy may be a favorable choice.

关键词： Right-sided round ligament Left-sided gallbladder Perihilar cholangiocarcinoma Case report

Effects of Fuscoporia obliqua on Postprandial Glucose Excursion and Endothelial Dysfunction in Type 2 Diabetic Patients

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Journal of Traditional Chinese Medicine 2008年第1期28卷 49-57页

作者： Toshihiro Maenaka Masami Oshima Yuka Itokawa Takashi Masubuchi Yasuyuki Takagi Jung-Sook Choi Torao ishida Yeunhwa Gu Graduate School of Health Science Suzuka University of Medical ScienceJapan Gyeongdo provincial college Kyoungbook Korea Hi-tech Research Center Suzuka University of Medical Science Japan Graduate School of Health Science Suzuka University of Medical Science Japan Hi-tech Research Center Suzuka University of Medical Science Japan

Postprandial hyperglycemia has been reported to elicit endothelial dysfunction and provoke future cardiovascular complications. A reduction of postprandial blood glucose levels by the glucosidase inhibitor Fuscoporia obliqua was associated with a risk reduction of cardiovascular complications, but the effects of Fuscoporia obliqua on endothelial function have never been elucidated. This study is aimed to assess the efficacy of Fuscoporia obliqua on postprandial metabolic parameters and endothelial function in type 2 diabetic patients. Postprandial peak glucose (14.47±1.27 vs. 8.50±0.53 mmol/liter), plasma glucose excursion (PPGE), and change in the area under the curve (AUC) glucose after a single loading of test meal (total 450 kcal; protein 15.3%; fat 32.3%; carbohydrate 51.4%) were significantly higher in the diet-treated type 2 diabetic patients (n=14) than the age-and sex-matched controls (n=12). The peak forearm blood flow response and total reactive hyperemic flow (flow debt repayment) during reactive hyperemia, indices of resistance artery endothelial function on strain-gauge plethysmography, were unchanged before and after meal loading in the controls. But those of the diabetics were significantly decreased 120 and 240 min after the test meal. A prior administration of Fuscoporia obliqua decreased postprandial peak glucose, PPGE, and AUC glucose. The peak forearm blood flow and flow debt repayment were inversely well correlated with peak glucose, PPGE, and AUC glucose, but not with AUC insulin or the other lipid parameters. Even a single loading of the test meal was shown to impair the endothelial function in type 2 diabetic patients, and the postprandial endothelial dysfunction was improved by a prior use of Fuscoporia obliqua. Fuscoporia obliqua might reduce macrovascular complication by avoiding endothelial injury in postprandial hyperglycemic status.

关键词： 2型糖尿病胰岛素中医疗效

Early serum albumin changes in patients with ulcerative colitis treated with tacrolimus will predict clinical outcome

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World Journal of Gastroenterology 2021年第22期27卷 3109-3120页

作者： Natsuki ishida Takahiro Miyazu Satoshi Tamura Shinya Tani Mihoko Yamade Moriya Iwaizumi Yasushi Hamaya Satoshi Osawa Takahisa Furuta Ken Sugimoto First Department of Medicine Hamamatsu University of School of MedicineHamamatsu 431-3192Japan Department of Laboratory Medicine Hamamatsu University of School of MedicineHamamatsu 431-3192Japan Department of Endoscopic and Photodynamic Medicine Hamamatsu University of School of MedicineHamamatsu 431-3192Japan Center for Clinical Research Hamamatsu University of School of MedicineHamamatsu 43131Japan

BACKGROUND Oral tacrolimus is a therapeutic agent for moderate to severe steroid-dependent or resistant ulcerative colitis(UC),but remission induction is difficult,and it is necessary to treat the patient while considering the next *** To examine serum albumin(Alb)level as a prognostic factor for the therapeutic effect of tacrolimus in clinical *** Forty-seven patients with UC treated with tacrolimus at our institution were divided into remission and failure groups(colectomy or switch to biologics),and the biological data at the start of observation and at weeks 1 and 2 were retrospectively ***-Meier and multivariate analyses were performed using Alb as a prognostic factor in UC *** During the three months observed,17(36.2%)patients failed treatment with tacrolimus.A comparison between the failure and remission groups showed a significant difference only in Alb in week 2,and in the week 2/week 0 Alb ratio,which showed the rate of change in *** cut-off value of the week 2/week 0 Alb ratio that predicted failure was 1,and its area under the curve was 0.751(95%CI:0.604-0.898).In the Kaplan-Meier analysis,a week 2/week 0 Alb ratio≤1 had a significantly higher failure rate than that of>1;Cox proportional hazard regression analysis also showed that a week 2/week 0 Alb ratio≤1 was an independent prognostic factor for failure within 3 mo after the start of tacrolimus *** A week 2/week 0 Alb ratio≤1 predicts failure within 3 mo of tacrolimus administration for *** failure risk exists with week 2 Alb values≤1 on admission.

关键词： Ulcerative colitis Tacrolimus Albumin

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一种耐高温聚苯并噁嗪的电化学合成

高等学校化学学报 2001年第3期22卷 506-507页

作者：万晓波何金波徐宁薛奇 ishida H. 南京大学化学化工学院高分子材料与工程系南京210093 DepartmentofPolymerScience

A new kind of polybenzoxazine could be synthesized by electrochemical method in acetonitrile/alkaline aqueous solution. The obtained polymer shows good heat resistance properties.

关键词：聚苯并恶嗪电化学聚合薄膜化学性质