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涂料技术与文摘 2003年第3期24卷 38-43页

作者： sakaguchi, Shinya

本发明涉及水性涂料用室温可固化树脂组合物,其基本上不含挥发性有机化合物(VOC),最低成膜温度(MFT)低,形成的涂膜具有优异的防粘连性和优异的各种物理性能,如耐水性、光滑性和耐候性.

关键词：水性涂料树脂组合物室温可固化耐水性光滑性耐候性

Time-dependent closure and permeability of a hydraulic fracture under constant normal stress

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Time-dependent closure and permeability of a hydraulic fract...

A Sandwich Technique Employing Right Ventricular Incision to Repair Posterior Ventricular Septal Rupture with Right Ventricular Wall Dissection: A Case Report

The 2001 ISRM International Symposium-2nd Asian Rock Mechanics Symposium(ISRM 2001-2nd ARMS)

作者： K.MATSUKI K.sakaguchi K.OKUMURA Tohoku University SendaiJapan

＜正＞Time-dependent closure and permeability of a small-scale hydraulic fracture created in granite and sandstone were measured under constant normal *** time-dependent closure increased to be constant at 50 to 70 hours for both *** ultimate time-dependent closure did not depend on the normal stress when the elastic closure curve obeyed the Goodman’s formula as for granite,while it increased with the normal stress when the elastic closure curve did not obey the Goodman’s formula as for sandstone. The hydraulic aperture decreased with time to be constant at about 50 hours for both *** hydraulic aperture produced by the elastic closure was very small（2.2 to 3.5μm）.and was finally 1.3 to 1.8μ*** larger the initial hydraulic aperture was,the more the hydraulic aperture decreased with time,regardless of the normal *** decrease in the hydraulic aperture was small in comparison with the increase in the time-dependent closure for both *** was because the fractures used in this study were all well mated and,accordingly,the contact area was developed well.

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World Journal of Cardiovascular Surgery 2023年第10期13卷 145-153页

作者： Daichi Sakurahara Koji Furukawa Hirohito Ishii Shuhei sakaguchi Katsuya Kawagoe Tomoaki Taniguchi Risa Meiri Department of Cardiovascular Surgery Faculty of Medicine University of Miyazaki Miyazaki Japan

Background: Ventricular septal rupture (VSR) leading to right ventricular (RV) wall dissection is an extremely rare and life-threatening complication of inferior myocardial infarction (MI) with posterior VSR. Its rare incidence and complex pathology make it difficult to select the appropriate surgical procedures to prevent fatalities. Case Presentation: A 68-year-old woman was transferred to our hospital because of a post-infarction VSR 12 days after symptom onset. Short-axis image obtained using transthoracic echocardiography demonstrated a large posterior VSR. Moreover, the VSR was continuous, with a large echo-free space in the posterior wall of the right ventricle. Color echocardiography showed blood flowing into the echo-free space through the septal defect and blood flowing out into the RV lumen. Coronary angiography revealed complete occlusion of the second segment of the right coronary artery. Thus, dissection of the posterior wall of the right ventricle that continued into the RV lumen was considered to have been caused by the posterior VSR caused by an inferior MI. The patient underwent urgent surgery to repair the VSR using the sandwich double-patch technique by making a posterior RV incision that was repaired using a third patch. No additional procedure was required to block the flow from the cavity of the RV wall dissection into the RV lumen. Postoperative echocardiography and contrast-enhanced computed tomography demonstrated that the VSR was closed securely and the RV wall dissection was almost completely thrombosed. Conclusion: In this case, a patient with a posterior VSR and RV wall dissection was successfully treated using the sandwich double-patch technique with a posterior RV incision. No additional procedure may be needed for RV wall dissection when a secure VSR repair is complete;however, close follow-up is essential to improve the long-term prognosis.

关键词： Ventricular Septal Rupture Right Ventricular Wall Dissection Surgery Sandwich Technique Right Ventricular Incision

Supraceliac Aortic Clamping for Repair of Ruptured Abdominal Aortic Aneurysm in Patients with Short Aortic Neck Length

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World Journal of Cardiovascular Surgery 2016年第1期6卷 5-13页

作者： Koji Furukawa Mitsuhiro Yano Eisaku Nakamura Masakazu Matsuyama Shuhei sakaguchi Katsuya Kawagoe Kunihide Nakamura Department of Cardiovascular Surgery Miyazaki Medical Association Hospital Miyazaki Japan Department of Cardiovascular Surgery University of Miyazaki Miyazaki Japan

Objective: Prompt bleeding control with proximal aortic clamping and subsequent aortic repair are very important for ruptured abdominal aortic aneurysm. However, unsuitable anatomy, such as short aortic neck length, not only disturbs the means to an expeditious repair, but may also increase morbidity and mortality. In the present study, we aimed to evaluate the efficacy of supraceliac aortic clamping for improving surgical outcomes for patients with ruptured abdominal aortic aneurysm, who have a short aortic neck length. Method: Between April 2010 and September 2015, eighteen patients underwent emergent open surgical repair of ruptured abdominal aortic aneurysm. Eight patients with a short aortic neck length underwent supraceliac aortic clamping, and 10 underwent infrarenal aortic clamping. Results: The mean supraceliac aortic clamping time was 30 ± 7 minutes. There was 1 operative death in the infrarenal aortic clamping group due to respiratory failure, and the overall operative mortality was 6%. There were no significant differences between the 2 groups with respect to postoperative complication rates or mortality. Furthermore, there were no significant differences in variables of renal function between the 2 groups, through-out the study period. Conclusion: Supraceliac aortic clamping was associated with minimal mortality and morbidity, but not with harmful effects on postoperative renal function. Thus, supraceliac aortic clamping can be safely applied for ruptured abdominal aortic aneurysm with short aortic neck length.

关键词： Ruptured Abdominal Aortic Aneurysm Short Aortic Neck Length Open Surgical Repair Supraceliac Aortic Clamping

Cell-Based Microfluidic Device Utilizing Cell Sheet Technology

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Cyborg and Bionic Systems 2022年第1期2022卷 35-42页

作者： Katsuhisa sakaguchi Kei Akimoto Masanori Takaira Ryu-ichiro Tanaka Tatsuya Shimizu Shinjiro Umezu Department of Integrative Bioscience and Biomedical Engineering Graduate School of Advaneed Science and Enginring TWInsWaseda University2-2 Wakamatsu-ChoShinju-KuTokyo 162-8480Japan Department of Modern Mechanical Engineering Graduate School of Creative Science and Engineering Waseda University 1-104 Totsuka-ChoShinju-KuTokyo 169-8555Japan Insttute of Advanced BiomedicalEngineering and Seience TWIns Tokyo Women's Medical University8-1 Kawada-ChoShinju-KuTokyo 162-8666Japan

The developmentof microelectromechanical systems hasresulted in the rapid development of polydimethylpolysiloxane(PDMS)microfluidic devices for drug screening *** cell functions,such as the response of endothelial cells to fluids,have beenelucdated using microuidic ***,organon-achip systems that includeorgans that are importantfor biologicalcirculation,such as the heart,liver,pancreas,kidneys,and brain,have been *** organs realize the biologicalcirculation system in a manner that cannot be reproduced by artificial organs;however,the flow channels between the organsare often artifically created by *** this study,we developeda microfluidic device consisting only of cels,by combiningcell sheet technology with microtitanium *** were placed between stacked fibroblast cellsheets,and the celisheets adhered to each other,afer which the microwires were removed leaving a luminal structure with a size approximatelyequal to the arteriolar *** lumen structure was constructed using wires with diameters of 50,100,150,and 200μm,which were approximations of the arteriole *** using a perfusion device,we successfully perfused theluminal structure created inside the *** results revealed that a aulture solution can be supplied toa cellsheet witha very high cell *** biofabrication technology proposed in this study can contribute to the development of organ-on-a-chip systems.

关键词： organs fluid diameters

Characterization of Bubble Liposomes by Measurements of Ultrasound Attenuation:Effects of Shell Materials

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Characterization of Bubble Liposomes by Measurements of Ultr...

Sessile serrated adenoma detection rate is correlated with adenoma detection rate

2008 IEEE International Ultrasonics Symposium

作者： Katsuji sakaguchi Nobuki Kudo Ryo Suzuki Kazuo Maruyama Katsuyki Yamamoto Hokkaido University Graduate school of Information Science and TechnologySapporoHokkaido Teikyo University Department of BiopharmaceuticsSchool of Pharmaceutical Sciences

＜正＞Background,Motivation and Objective"Bubble liposomes"are gas-encapsulated liposomes of several hundred nanometers in *** bubbles are expected to create new applications in the field of gene delivery and drug del...

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World Journal of Gastrointestinal Oncology 2018年第3期10卷 82-90页

作者： Daisuke Ohki Yosuke Tsuji Tomohiro Shinozaki Yoshiki sakaguchi Chihiro Minatsuki Hiroto Kinoshita Keiko Niimi Satoshi Ono Yoku Hayakawa Shuntaro Yoshida Atsuo Yamada Shinya Kodashima Nobutake Yamamichi Yoshihiro Hirata Tetsuo Ushiku Mitsuhiro Fujishiro Masashi Fukayama Kazuhiko Koike Department of Gastroenterology Graduate School of Medicinethe University of Tokyo Department of Biostatistics School of Public Healththe University of Tokyo Center for Epidemiology and Preventive Medicine Graduate School of Medicinethe University of Tokyo Department of Endoscopy and Endoscopic Surgery Graduate School of Medicinethe University of Tokyo Department of Pathology Graduate School of Medicine the University of Tokyo

AIM To investigated the association between adenoma detection rate(ADR) and sessile serrated ADR(SSADR) and significant predictors for sessile serrated adenomas(SSA) *** This study is a retrospective, single-center analysis. Total colonoscopies performed by the gastroenterologists at the University of Tokyo Hospital between January and December 2014 were retrospectively identified. Polyps were classified as low-grade or high-grade adenoma, cancer, SSA, or SSA with cytological dysplasia, and the prevalence of each type of polyp was investigated. Predictors of adenoma and SSA detection were examined using logistic generalized estimating equation models. The association between ADR and SSADR for each gastroenterologist was investigated by calculating a correlation coefficient weighted by the number of each gastroenterologist's *** A total of 3691 colonoscopies performed by 35 gastroenterologists were assessed. Overall, 978 (26.5%) low-and 84 (2.2%) high-grade adenomas, 81 (2.2%) cancers, 66 (1.8%) SSAs, and 2 (0.1%) SSAs with cytological dysplasia were detected. Overall ADR was 29.5%(men 33.2%, women 23.8%) and overall SSADR was 1.8%(men 1.7%, women 2.1%). In addition, 672 low-grade adenomas (68.8% of all the detected lowgrade adenomas), 58 (69.9%) high-grade adenomas, 29 (34.5%) cancers, 52 (78.8%) SSAs, and 2 (100%) SSAs with cytological dysplasia were found in the proximal colon. Adenoma detection was the only significant predictor of SSA detection (adjusted OR: 2.53, 95%CI: 1.53-4.20; P < 0.001). The correlation coefficient between ADR and SSADR weighted by the number of each gastroenterologist's examinations was 0.606(P < 0.001).CONCLUSION Our results demonstrated that ADR is correlated to SSADR. In addition, patients with adenomas had a higher prevalence of SSAs than those without adenomas.

关键词： Sessile serrated adenoma Sessile serrated adenoma detection rate Adenoma detection rate Colonoscopy Interval colorectal cancer

Simulation of rice paddy systems in SWAT:A review of previous applications and proposed SWAT+rice paddy module

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International Journal of Agricultural and Biological Engineering 2022年第1期15卷 1-24页

作者： Philip W.Gassman Jaehak Jeong Julien Boulange Balaji Narasimhan Tasuku Kato Hiroaki Somura Hirozumi Watanabe Sadao Eguchi Yuanlai Cui Atsushi sakaguchi Le Hoang Tu Rui Jiang Min-Kyeong Kim Jeffrey G.Arnold Wei Ouyang Center for Agricultural and Rural Development Iowa State UniversityAmesIowa 50011-1070USA Blackland Research&Extension Center Texas A&M AgriLifeTempleTexas 76502USA Department of International Environmental and Agricultural Sciences Tokyo University of Agriculture and TechnologyFuchuTokyo 183-8509Japan Department of Civil Engineering Indian Institute of Technology MadrasChennai 600036India Graduate School of Environmental and Life Science Faculty of EngineeringOkayama UniversityOkayama 700-8530Japan Institute for Agro-Environmental Sciences National Agriculture and Food Research OrganizationTsukuba 305-8604Japan State Key Laboratory of Water Resources and Hydropower Engineering Science Wuhan UniversityWuhan 430072China Department of Biological&Environmental Sciences Faculty of AgricultureYamaguchi UniversityYamaguchi 753-8515Japan Key Laboratory of Plant Nutrition and the Agri-environment in Northwest China Ministry of AgricultureCollege of Natural Resources and EnvironmentNorthwest A&F UniversityYangling 712100ShaanxiChina Rural Development Administration Jeonju54875Republic of Korea Grassland Soil and Water Research Laboratory U.S.Department of Agriculture-Agricultural Research ServiceTempleTexas 76502USA School of Environment State Key Laboratory of Water Environment SimulationBeijing Normal UniversityBeijing 100875China

The Soil and Water Assessment Tool(SWAT)is an ecohydrological watershed-scale model which was initially developed in the early 1990s to simulate the impacts of land use,management systems,and climate on hydrology and/or water *** adopted in the U.S.,the use of the model then spread to Europe and then later to Asia and other *** range of applications that SWAT has been applied to have also expanded dramatically,which influenced ongoing model development which has been virtually continuous over the past two decades.A key component of many SWAT applications in Asia is accounting for rice paddy production that is common in some subregions within the ***,most of these studies do not provide explicit details of how rice production was simulated in *** research has revealed that significant problems occur when trying to represent rice paddy systems in standard versions of SWAT,due to limitations in algorithms based on the runoff curve number approach or the pothole *** response,key modifications have been made to SWAT in recent studies that have resulted in more accurate representation of rice paddy *** developments point to the need for the incorporation of an enhanced rice paddy module within SWAT to better capture rice paddy hydrological and pollutant dynamics,which would support improved use of the model in Asia and other rice production *** related to simulating rice production in SWAT are discussed as follows:1)an overview of global rice production;2)history of SWAT development;3)typical approaches for simulating rice production;4)problems associated with the typical approaches;5)recent code modifications to address deficiencies in replicating rice paddy systems;6)recommendations for developing a standard rice paddy module for future SWAT codes.

关键词： SWAT rice paddies potholes hydrology pollutants modified SWAT models

Evaluation of preferable insertion routes for esophagogastroduodenoscopy using ultrathin endoscopes

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World Journal of Gastroenterology 2014年第17期20卷 5045-5050页

作者： Satoshi Ono Keiko Niimi Mitsuhiro Fujishiro Yu Takahashi Yoshiki sakaguchi Chiemi Nakayama Chihiro Minatsuki Rie Matsuda Itsuko Hirayama-Asada Yosuke Tsuji Satoshi Mochizuki Shinya Kodashima Nobutake Yamamichi Atsuko Ozeki Lumine Matsumoto Yumiko Ohike Tsutomu Yamazaki Kazuhiko Koike Center for Epidemiology and Preventive Medicine Graduate School of MedicineUniversity of TokyoTokyo 113-8655Japan Department of Gastroenterology Graduate School of MedicineUniversity of TokyoTokyo 113-8655Japan Department of Endoscopy and Endoscopic Surgery Graduate School of MedicineUniversity of TokyoTokyo 113-8655Japan

AIM: To evaluate the discomfort associated with esophagogastroduodenoscopy (EGD) using an ultrathin endoscope through different insertion routes.

关键词： Esophagogastroduodenoscopy Ultrathin endoscope Visual analog scale

Comparing reduced-dose sodium phosphate tablets to 2L of polyethylene glycol: A randomized study

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World Journal of Gastroenterology 2017年第24期23卷 4454-4461页

作者： Soichiro Ako Koji Takemoto Eriko Yasutomi Chihiro sakaguchi Mayu Murakami Tomoko Sunami Shohei Oka Hamada Kenta Noriko Okazaki Yuki Baba Yasushi Yamasaki Toshiyuki Asato Daisuke Kawai Ryuta Takenakai Hirohumi Tsugeno Sakiko Hiraoka Jun Kato Shigeatsu Fujiki Department of Gastroenterology Tsuyama Chuo HospitalTsuyama City Department of Gastroenterology and Hepatology Okayama University Graduate School of MedicineDentistry and Pharmaceutical Sciences Second Department of Internal Medicine Wakayama Medical UniversityWakayama city

To compare the tolerability and quality of bowel cleansing between 2 L polyethylene glycol (PEG) and reduced-dose sodium phosphate (NaP) tablets as a preparation for colonoscopy. METHODSTwo hundred patients were randomly assigned to the PEG or NaP groups at the same ratio. The NaP group patients took 30 tablets with 2 L of clear liquid, while the PEG group patients took 2L of PEG. Tolerability was assessed by a questionnaire about taste, volume, and the overall impression. The bowel cleansing quality was evaluated by colonoscopists. RESULTSAlthough NaP showed better tolerability in terms of taste, volume and overall impression (P < 0.01, P < 0.01 and P = 0.02, respectively), the overall cleansing quality was better in the PEG group (P < 0.01). A subgroup analysis, stratified by sex and age, indicated that NaP was associated with better tolerability and equivalent bowel cleansing quality in females of < 50 years of age. CONCLUSIONDespite the better tolerability, the use of 30 NaP tablets with 2 L of clear liquid should be limited due to its lower cleansing quality; however, in certain cases the regimen may deserve consideration, particularly in cases involving young women.

关键词： Colonoscopy Sodium phosphate tablets Polyethylene glycol Preparation