检索结果-南通市图书馆

Scalable fabrication of microneedle arrays via spatially controlled UV exposure

Microsystems & Nanoengineering 2016年第1期2卷 73-81页

作者： hidetoshi takahashi Yun Jung Heo Nobuchika Arakawa Tesuo Kan Kiyoshi Matsumoto Ryuji Kawano Isao Shimoyama Department of Mechano-Informatics Graduate School of Information Science and Technologythe University of Tokyo7-3-1 HongoBunkyo-kuTokyo 113-8656Japan Department of Mechanical Systems Engineering Graduate School of EngineeringTokyo University of Agriculture and Technology2-24-16 Naka-choKoganei-shiTokyo 184-8588Japan Department of Mechanical Engineering and Intelligent Systems Graduate School of Informatics and Engineeringthe University of Electro-Communications1-5-1 ChofugaokaChofu-shiTokyo 182-8585Japan IRT Research Initiative the University of Tokyo7-3-1 HongoBunkyo-kuTokyo 113-8656Japan Department of Biotechnology and Life Science Graduate School of EngineeringTokyo University of Agriculture and Technology2-24-16 Naka-choKoganei-shiTokyo 184-8588Japan

This paper describes a theoretical estimation of the geometry of negative epoxy-resist microneedles prepared via inclined/rotated ultraviolet(UV)lithography based on spatially controlled UV exposure *** comparison with other methods based on UV lithography,the present method can create microneedle structures with high *** negative photoresist is exposed to inclined/rotated UV through circular mask patterns,a three-dimensional,needle-shaped distribution of the exposure dose forms in the irradiated *** the inclination angles and the exposure dose modifies the photo-polymerized portion of the photoresist,thus allowing the variation of the heights and contours of microneedles formed by using the same mask *** an experimental study,the dimensions of the fabricated needles agreed well with the theoretical predictions for varying inclination angles and exposure *** results demonstrate that our theoretical approach can provide a simple route for fabricating microneedles with on-demand *** fabricated microneedles can be used as solid microneedles or as a mold master for dissolving microneedles,thus simplifying the microneedle fabrication *** envision that this method can improve fabrication accuracy and reduce fabrication cost and time,thereby facilitating the practical applications of microneedle-based drug delivery technology.

关键词： inclined/rotated lithography microneedle array UV exposure ratio

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Atrophoderma Vermiculata Successfully Treated by 595 nm Dye Laser and Carbon Dioxide Laser

引用

Journal of Cosmetics, Dermatological Sciences and Applications 2012年第3期2卷 130-131页

作者： hidetoshi takahashi Yoshio Hashimoto Masuru Honma Akemi Ishida-Yamamoto Hajime Iizuka Department of Dermatology Asahikawa Medical University Asahikawa Japan

The treatment of atrophoderma vermiculatum is challenging. A 7-year-old girl had a unilateral atrophic skin lesion on her right cheek, which was diagnosed as unilateral atrophoderma vermiculata. She was treated by carbon dioxide and 595 nm pulsed dye laser and carbon dioxide laser. This resulted in prevention of the lesional progression with favorable cosmetic appearance of the skin.

关键词： Atrophoderma Vermiculata Dyed Laser Carbon Dioxide Laser

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Telemonitoring of Patients with Implantable Cardiac Devices to Manage Heart Failure: An Evaluation of Tablet-PC-Based Nursing Intervention Program

引用

Open Journal of Nursing 2014年第4期4卷 237-250页

作者： Aya Umeda Tomoko Inoue Takuri takahashi hidetoshi Wakamatsu Department of Critical and Invasive-Palliative Care Nursing Tokyo Medical and Dental University Tokyo Japan Department of Life Sciences and Bio-Informatics Tokyo Medical and Dental University Tokyo Japan National Institute of Infectious Diseases Tokyo Japan

Background: With the rapid aging of society, the number of patients with heart failure has also increased. Implantable devices for heart failure have become standardized. Remote monitoring using cardiac devices has grown in popularity for medical efficiency and the early detection of abnormalities. Our first aim was to develop a tablet-PC-based nursing intervention program for patients requiring remote monitoring of implantable cardiac devices. The second purpose was to evaluate the efficacy of the program by using mixed-methods research. Methods: The study consisted of two phases. In phase 1, we designed a tablet-PC-based nursing intervention program, on the basis of a literature review and qualitative data collected via semi-structured interviews. In phase 2, we conducted a randomized controlled trial that served as a preliminary investigation of the program. The outcome measures were readmission, unexpected visits to the clinic for heart problems, quality of life, self-care behavior, and self-efficacy. After the study, we interviewed each participant about his or her experiences with the program. Interviews were audio recorded, coded, and thematically analyzed. Results: The 33 patients with heart failure were randomized into two groups as follows: 17 patients in the telenursing group and 16 in the control group. During 6 months of follow-up, the readmission for heart failure occurred in 11% of the intervention group and 18% of the control group. There were no statistically significant differences between the groups at any outcome measures. Three themes were extracted via qualitative analysis: “getting a sense of safety,” “triggering a health behavior change,” and “feeling like a burden.” Conclusion: No improvements in rates of rehospitalization or unexpected clinic visits were seen in the quantitative study. However, signs of behavior modification were seen in the qualitative study. This program has the possibility of improving patient outcomes.

关键词： Heart Failure Telemonitoring Telenursing Remote Monitoring Implantable Cardiac Devices

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：