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Preparation and ^(99m)Tc labeling of hydrazino nicotinamidemodified RC-160 conjugate

Nuclear Science and Techniques 2001年第2期12卷 94-98页

作者： HU Ji, SUZUKI Kazuko Horiuchi1, saji hideo1 (Isotope Department, China Institute of Atomic Energy, Beijing 102413 1Kyoto University’s Graduate School of Pharmaceutical Sciences Department of Patho-Functional Bioanalysis, Kyoto, Japan ) 中国原子能科学院同位素所北京 102413 日本京都大学药学研究生院日本

Conjugations of 6-Boo-hydrazinopyridine-3-carboxylic acid(Boc-HYNIC) with RC-160 [Lys5, Boc] using different coupling methods were studied. After deprotection, the resulted peptide conjugates were purified by RP-HPLC and characterized by Fab-MS. Combination with different coligands, 99mTc labeling of HYNIC modified RC-160 conjugate was carried out with high radiolabeling yield (>95%). In vitro stability studies indicated that the final radio-compound remained stable at least up to 20 h when nicotinic acid (NA) used as second coligand (tricine/NA).

关键词：结合作用 ^99mTc标记生长激素释放抑制因子

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Greater omentum gastrointestinal stromal tumor with PDGFRA-mutation and hemoperitoneum

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World Journal of Gastrointestinal Oncology 2012年第5期4卷 119-124页

作者： Yoko Murayama Masayuki Yamamoto Ryuichiro Iwasaki Tamana Miyazaki Yukiko saji Yoshinori Doi Haruki Fukuda Seiichi Hirota Masahiro Hiratsuka Department of Gastroenterology and Hepatology Itami City HospitalItami 6648540Japan Department of Surgery Itami City HospitalItami 6648540Japan Department of Gastroenterology and Hepatology Otemae HospitalOsaka 5400008Japan Department of Pathology Itami City HospitalItami 6648540Japan Department of Surgical Pathology Hyogo College of MedicineNishinomiya 6638501Japan

Although gastrointestinal stromal tumor(GIST) occurs generally in the digestive tract,omental GIST is very *** report the first case of an adult greater omental GIST with a new platelet-derived growth factor receptor α gene(PDGFRA)-mutation with hemoperitoneum.A 43-year-old man was admitted to our hospital complaining of acute abdominal *** contrast-enhanced computed tomography revealed a huge mass in the right abdominal cavity,and a large accumulation of fluid in the pelvic cavity,suggesting *** diagnosed the rupture as an intra-abdominal tumor,and an emergency tumorectomy was performed with resection of the greater *** tumor was located in the distal right side ofthe greater omentum,and showed no continuity with the gastric *** tumor occurred primarily in the greater *** resected tumor was about 19 cm × 12 cm × 14 cm in diameter,and weighed 1529 ***,the tumor was composed of epithelioidshaped cells with high cellularity,and was positive for CD117 and CD34,and negative for S-100,α-smooth muscle *** mitosis was 6/50 under high power *** case showed exon 18 mutation of PDGFRA with 846(Asp to Glu) substitution,848(Asn to Lys) *** is the first report of this PDGFRA mutation in omental GIST,and this might play an important role in the tumorigenesis of this *** on these findings,the tumor was diagnosed as high risk GIST primarily occurring in the greater *** patient was treated with imatinib at a dose of 400 mg/d as adjuvant chemotherapy,and has been followed up for 24 mo with no evidence of recurrence.

关键词： Gastrointestinal stromal tumor Greater omentum Hemoperitoneum Platelet-derived growth factor receptor α gene KIT

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日本人汉语学习者近义动词范畴化特征研究

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现代外语 2018年第4期41卷 493-504页

作者：王冲洪春子佐治伸郎刘晓颖大连理工大学御茶水女子大学镰仓女子大学

本文以"切割"类动词为研究对象,通过实验方法分析了日本人汉语学习者近义动词范畴化的特征。研究发现:学习者的语义范畴化习得受到了母语"为言而思"方式的影响,并出现了目标语中使用范围较广词汇、以及母语中使用范围较广词汇所对应的... 详细信息

本文以"切割"类动词为研究对象,通过实验方法分析了日本人汉语学习者近义动词范畴化的特征。研究发现:学习者的语义范畴化习得受到了母语"为言而思"方式的影响,并出现了目标语中使用范围较广词汇、以及母语中使用范围较广词汇所对应的目标语词汇的泛化现象;范畴化基准的特征是影响习得难易程度的一个重要因素;目标语中感知较显著的范畴化基准更容易习得,母语中感知较显著的范畴化基准容易发生迁移。

关键词：范畴化模式范畴化基准过度泛化为言而思

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丸山升先生的思想、人格和学问——日本东方学会“缅怀先学丸山升先生”座谈会记录

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现代中文学刊 2019年第4期 11-31页

作者：竹田晃佐治俊彦尾崎文昭藤井省三长堀祐造及川淳子王俊文(译) 铃木将久(校) 东京大学明海大学 "东阳文库" 和光大学庆应义塾大学樱美林大学不详

丸山升先生是日本著名的鲁迅研究家和中国现代文学研究家。2016年10月他去世十年之际,日本东方学会邀请日本学界不同世代的学者举行座谈会,缅怀和回顾丸山先生的生平、思想和相关研究,其内容实乃以丸山升先生为线索、以鲁迅研究为中心... 详细信息

丸山升先生是日本著名的鲁迅研究家和中国现代文学研究家。2016年10月他去世十年之际,日本东方学会邀请日本学界不同世代的学者举行座谈会,缅怀和回顾丸山先生的生平、思想和相关研究,其内容实乃以丸山升先生为线索、以鲁迅研究为中心而串连起来的日本战后关于中国革命和中国现代文学研究的学术史,具有丰富的历史内容。该座谈记录刊于2017年1月《东方学》第133辑。

关键词：《东方学》丸山升座谈会日本学会中国现代文学研究学问人格

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Comparison of Survey Results on Subjective Dizziness,Hearing and Tinnitus and Stabilometry Test Results in Yakumo Inhabitant Examination Study (Comparison of 2005, 2007 and 2015, 2017)

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Journal of Health Science 2019年第3期7卷 151-159页

作者： Naomi Katayama Shoko Kondo Yui Nakayama Takafumi Nakada Naoki saji Seiya Goto Satofumi Sugimoto Wakako kinoshita Masaaki Teranisi Michihiko Sone Yasushi Fujimoto Hironao Otake Hirokazu Suzuki Seiichi Nakata Tsutomu Nakashima Yukiharu Hasegawa Nagoya Women’s University Nagoya City 467-8610Japan Graduate School of Nagoya Women’s University Nagoya City 467-8610Japan Department of Otorhinolaryngology Nagoya University Graduate School of MedicineNagoya City 466-8550Japan Watanabe Hospital Mihama TownChita-gun 470-3235Japan National Center for Geriatrics and Gerontology Obu City 474-851Japan Otake Otolaryngology Hospital Kariya City 448-0857Japan Department of Otolaryngology Second Hospital Fujita Health University School of MedicineNagya City 545-8509Japan Ichinomiya Medical Treatment &Habitaiton Center Ichinomiya City 494-0018Japan Department of Occupational Therapy Kansai University of Welfare SciencesOsaka fu 582-0026Japan

Abstract: The Nagoya University Hospital otolaryngology department is doing the prospective cohort study in Yakumo-cho, Hokkaido, Japan from 2005, because this place is a little transfer of the population. Most of inhabitants of Yakumo-cho engage in fishery and agriculture as work mainly. We perform questionary survey using an interview vote. The item is “having feeling of dizziness or not”,“quality of hearing” and “having tinnitus or not”. Furthermore, we go for the examination of stabilometry, too. We compared 2015, 2017 with 2005, 2007 among Yakumo-cho inhabitant examination data this time. As a result, participant with a feeling of conscious dizziness got a bad reputation of the hearing consciously. In addition, participant with a feeling of conscious dizziness had tinnitus consciously. Furthermore, the participant with a feeling of conscious dizziness had bad stabilometry result. As a result of having compared ten years later, we understood that stabilometry result worsened if 60s became in 70s with or without a feeling of dizziness consciously. When there is a feeling of conscious dizziness, it is necessary to perform an examination of stabilometry as routine work. In addition, it is necessary to inspect stabilometry if participants have the bad hearing or tinnitus with a feeling of dizziness in particularly.

关键词： Feeling of dizziness hearing tinnitus stabilometry Yakumo study

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