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Hepatobiliary Surgery and Nutrition 2021年第2期10卷 261-263页

作者： Hiromitsu Hayashi hideo Baba Department of Gastroenterological Surgery Graduate School of Life SciencesKumamoto UniversityKumamotoJapan

We congratulate *** and colleagues for their recently published study entitled“Precision oncology in surgery:Patient selection for operable pancreatic cancer”in Annals of Surgery(1).In this unique study,the authors tried to define preoperative clinical and molecular characteristics in order to improve patient selection for operable pancreatic *** ductal adenocarcinoma(PDAC)remains the most lethal type of human cancer due to its high chemoresistance and invasiveness(2).In resected PDAC,the median overall survival has increased from 22.1 to 35 months during the past 10 years,largely owing to improvements in adjuvant therapies(3,4).On the other hand,the high recurrence rate even in patients who underwent curative resection,and chemoresistance in the recurrent sites to current systemic chemotherapies(FOLFIRINOX and nab-paclitaxel plus gemcitabine),are major issues in the treatment for unselected PDAC patient *** resection offers the only chance of cure,but surgery can be associated with significant morbidity and decreased activity of daily life(ADL),especially in the Whipple procedure(pancreaticoduodenectomy).Recently,the importance of preoperative chemotherapy even in operable PDAC has been increasingly recognized(5).Although molecular markers are being used more frequently to select patients for systemic targeted agents,only imaging modalities are used to stage patients and to assess their suitability for operative *** on primary surgery or a neoadjuvant approach are made without evaluation of biological measures of tumor aggressiveness,or of the risk of occult metastatic disease.

关键词： surgery cancer Surgery

Liver resection for hepatocellular carcinoma associated with hepatic vein invasion: is it time to reconsider the current treatment guidelines?

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Hepatobiliary Surgery and Nutrition 2018年第4期7卷 300-301页

作者： Katsunori Imai hideo Baba Department of Gastroenterological Surgery Graduate School of Life Sciences Kumamoto University Kumamoto Japan

Hepatocellular carcinoma (HCC) is the most common primary liver cancer and is responsible for 70–90% of cases (1,2).The presence of macrovascular invasion such as portal vein tumor thrombus (PVTT) or hepatic vein tum... 详细信息

关键词： invasion hepatic thrombus

Numerical and Experimental Studies of an Arc-heated Nonequilibrium Nozzle Flow

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Journal of Thermal Science 2003年第4期12卷 289-293页

作者： Michio Nishida Ken-ichi abe Hisashi Kihara Department of Aeronautics and Astronautics Kyushu University Fukuoka 812-8581 JapanDepartment of Aeronautics and Astronautics Kyushu University Fukuoka 812-8581 JapanDepartment of Aeronautics and Astronautics Kyushu University Fukuoka 812-8581 Japan

The arc-heated high-temperature gas is rotationally and vibrationally excited, and partially dissociated and ionized. When such gas flows inside a nozzle, energy transfers from rotational and vibrational energy modes to translational energy mode, and, in addition, recombination reactions occur. These processes are in thermal and chemical nonequilibrium. The present computations treat arc-heated nonequilibrium nozzle flows using a six temperature model (translational, rotational, N2 vibrational, O2 vibrational, NO vibrational and electron temperatures), and nonequilibrium chemical reactions of air. From the calculated flow properties, emission spectra at the nozzle exit were re-constructed by using the code for computing spectra of high temperature air. On the other hand, measurements of N2+(1-) emission spectra were conducted at the nozzle exit in the 20 kW arc-heated wind tunnel. Vibrational and rotational temperatures of N2 were determined using a curve fitting method on N2+(1-) emission spectra, with the vibrational and rotational temperatures for N2 and N2+ being assumed equal. Comparison of the measured and computed results elucidated that the experimental temperatures were larger than the computed ones. At present, we are trying to reveal the main reason for the discrepancy between the computed and measured N2 vibrational and rotational temperatures.

关键词： nozzle flow high temperature gas nonequilibrium flow arc-heated gas.

Probing the fate of transplanted hematopoietic stem cells: is the combinational approach “FIT” for purpose?

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Science China(Life Sciences) 2020年第11期63卷 1755-1758页

作者： Fang Dong Hui Cheng hideo Ema Tao Cheng State Key Laboratory of Experimental Hematology National Clinical Research Center for Blood DiseasesInstitute of Hematology&Blood Diseases HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeTianjin 300020China Center for Stem Cell Medicine Chinese Academy of Medical SciencesTianjin 300020China Department of Stem Cell&Regenerative Medicine Peking Union Medical CollegeTianjin 300020China

Hematopoietic stem cells (HSCs)—with their self-renewal and multi-lineage differentiation potential—are top of the hematopoietic cell hierarchy. Stress conditions activate the quiescent HSCs, which in turn enter cel... 详细信息

关键词： hematopoietic al. stem

Laparoscopic right hemicolectomy for ascending colon cancer with persistent mesocolon

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World Journal of Gastroenterology 2014年第18期20卷 5557-5560页

作者： Atsushi Tsuruta Akimasa Kawai Yasuo Oka hideo Okumura hideo Matsumoto Toshihiro Hirai Masafumi Nakamura Department of Digestive Surgery Kawasaki Medical SchoolOkayama 701-0192Japan

Persistent ascending or descending mesocolon is an embryological anomaly that occurs during the final process of intestinal development in ***,the primitive dorsal mesocolon fails to fuse with the parietal peritoneum in the fifth month of ***,we describe a case of ascending colon cancer with persistent ascending and descending mesocolon treated by laparoscopic right *** computed tomography imaging of the abdomen demonstrated that the descending colon shifted at the midline of the abdomen and the sigmoid colon was located under the ascending *** detailed preoperative imaging examination revealed malpositioning of the large intestine and aided in the procedural *** persistent mesocolon may result in the formation of abnormal adhesions,an accurate preoperative diagnosis is *** propose that it is important to consider this anomaly when making the preoperative imaging diagnosis to ensure a safe operation.

关键词： Laparoscopic surgery Colon cancer Persistent descending mesocolon Persistent ascending mesocolon Mobile cecum

Crystal structure,chemical bond characteristics,infrared reflection spectrum,and microwave dielectric properties of Nd_(2)(Zr_(1−x)Ti_(x))_(3)(MoO_(4))_(9) ceramics

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Journal of Advanced Ceramics 2023年第1期12卷 82-92页

作者： Jian BAO Yuping ZHANG hideo KIMURA Haitao WU Zhenxing YUE School of Environmental and Material Engineering Yantai UniversityYantai 264005China State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing 100084China

Microwave dielectric ceramics(MWDCs)with low dielectric constant and low dielectric loss are desired in contemporary society,where the communication frequency is developing to high frequency(sub-6G).Herein,Nd_(2)(Zr_(1−x)Ti_(x))_(3)(MoO_(4))_(9)(NZ_(1−x)T_(x)M,x=0.02-0.10)ceramics were prepared through a solid-phase *** to X-ray diffraction(XRD)patterns,the ceramics could form a pure crystal structure with the R3c(167)space *** internal parameters affecting the properties of the ceramics were calculated and analyzed by employing Clausius-Mossotti relationship,Shannon’s rule,and Phillips-van Vechten-Levine(P-V-L)***,theoretical dielectric loss of the ceramics was measured and analyzed by a Fourier transform infrared(IR)radiation ***,when x=0.08 and sintered at 700℃,optimal microwave dielectric properties of the ceramics were obtained,including a dielectric constant(ε_(r))=10.94,Q·f=82,525 GHz(at 9.62 GHz),and near-zero resonant frequency temperature coefficient(τ_(f))=−12.99 ppm/℃.This study not only obtained an MWDC with excellent properties but also deeply analyzed the effects of Ti^(4+)on the microwave dielectric properties and chemical bond characteristics of Nd_(2)Zr_(3)(MoO_(4))_(9)(NZM),which laid a solid foundation for the development of rare-earth molybdate MWDC system.

关键词： microwave dielectric ceramics(MWDCs) Nd_(2)(Zr_(1−x)Ti_(x))_(3)(MoO_(4))_(9)(NZ_(1−x)T_(x)M) Phillips-van Vechten-Levine(P-V-L)theory theoretical dielectric loss

Efficacy of balloon-occluded retrograde transvenous obliteration, percutaneous transhepatic obliteration and combined techniques for the management of gastric fundal varices

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World Journal of Gastroenterology 2006年第24期12卷 3866-3873页

作者： Hirotaka Arai Takehiko abe Hitoshi Takagi Masatomo Mori Department of Gastroenterology Maebashi Red Cross Hospital 3-20-14 Asahi-choMaebashi 371-0014Japan Department of Medicine and Molecular Science Gunma University Graduate School of Medicine (previously known as the First Department of Internal Medicine Gunma University School of Medicine)MaebashiGunma 371-8511Japan

AIM： To evaluate the effect of three interventional treatments involving transvenous obliteration for the treatment of gastric varices, and to compare the efficacy and adverse effects of these methods, METHODS： From 1995 to 2004, 93 patients with gastric fundal varices underwent interventional radiologic embolotherapy at our hospital. Of the 93 patients, 75 were treated with the balloon-occluded retrograde transvenous obliteration （BRTO） procedure; 8 were with the percutaneous transhepatic obliteration （PTO） procedure; and 10 were with the combined BRTO and PTO therapy. A follow-up evaluation examined the rates of survival, recurrence and rebleeding of the gastric varices, worsening of esophageal varices and complications in each group. RESULTS： The BRTO, PTO, and combined therapy were technically successful in 81% （75/93）, 44% （8/18）, and 100% （10/10） patients, respectively. Recurrence of gastric varices was found in 3 patients in the BRTO group and in 3 patients in the PTO group. Rebleeding was observed in 1 patient in the BRTO group and in 1 patient in the PTO group. The 1- and 3-year survival rates were 98% and 87% in the patients without hepatocellular carcinoma （HCC） in the BRTO group, 100% and 100% in the PTO group, and 90% and 75% in the combined therapy group, respectively. CONCLUSION： Combined BRTO and PTO therapy may rescue cases with uncontrollable gastric fundal varices that remained even after treatment with BRTO and/or PTO, though there were limitations of our study, including retrospective nature and discrepancy in sample size between the BRTO, PTO and combined therapy groups.

关键词： Gastric varices Balloon-occluded retrogradetransvenous obliteration Percutaneous transhepaticobliteration Combined therapy

The gut microbiome, antitumor immunity, and liver cancer

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Hepatobiliary Surgery and Nutrition 2019年第1期8卷 67-68页

作者： Kosuke Mima hideo Baba Department of Surgery National Hospital Organization Kumamoto Medical CenterKumamotoJapan Department of Gastroenterological Surgery Graduate School of Medical ScienceKumamoto UniversityKumamotoJapan

Primary liver cancer is one of the leading causes of cancer deaths globally(1).Hepatocellular carcinoma(HCC)is the most common primary liver malignancy,and the major risk factors for HCC include hepatitis B and C,alcohol consumption,non-alcoholic fatty liver disease,and liver cirrhosis(2).The liver is the common site of metastasis from breast,lung,and colorectal cancer,and malignant melanoma(3).

关键词： immunity cancer liver

Surface-mounted bender elements for measuring horizontal shear wave velocity of soils

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第11期9卷 1490-1496页

作者： Yan-guo ZHOU Yun-min CHEN Yoshiharu ASAKA Tohru abe MOE Key Laboratory of Soft Soils and Geoenvironmental Engineering Zhejiang University Hangzhou 310027 China Institute of Geotechnical Engineering Zhejiang University Hangzhou 310027 China Institute of Technology Shimizu Corporation Tokyo 135-8530 Japan

The bender element testing features its in-plane directivity, which allows using bender elements to measure the shear wave velocities in a wider range of in-plane configurations besides the standard tip-to-tip alignment. This paper proposed a novel bender element testing technique for measuring the horizontal shear wave velocity of soils, where the bender elements are surface- mounted and the axes of the source and receiver elements are parallel to each other. The preliminary tests performed on model ground of silica sand showed that, by properly determining the travel distance and time of the shear waves, the surface-mounted bender elements can perform as accurately as the conventional "tip-to-tip" configuration. Potentially, the present system provides a promising nondestructive tool for characterizing geomaterials and site conditions both in laboratory and in the fields.

关键词： Bender elements Shear wave velocity Model test Nondestructive evaluation Surface-mounted Sand

Preparation and characterization of tea tree oil-β-cyclodextrin microcapsules with super-high encapsulation efficiency

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生物质资源与工程(英文) 2023年第3期8卷 224-234页

作者： Peifu Kong Junichi Peter abe Shunsuke Masuo Toshiharu Enomae Degree Programs in Life and Earth Sciences University of TsukubaIbaraki 305-8572Japan Faculty of Life and Environmental Sciences University of TsukubaIbaraki305-8572Japan

This study aimed to prepare tea tree oil-β-cyclodextrin microcapsules using an optimized co-precipitated *** impact of the volume fraction of ethanol in the solvent system for microencapsulation on encapsulation efficiency was investigated and analyzed ***-high encapsulation efficiency was achieved when a 40%volume fraction of ethanol was used for the microencapsulation procedure,where the recovery yield of microcapsules and the embedding fraction of tea tree oil in microcapsules were as high as 88.3%and 94.3%,***,considering the operation cost,including time and energy consumption,an economical preparation was validated so that it would be viable for large-scale *** on the results of morphological and X-ray diffraction analysis,the crystal structure appeared to differ before and after *** results of gas chromatography-mass spectrometry and Fourier transform infrared spectroscopy confirmed the successful formation of ***,the antibacterial activity of the fabricated microcapsules was assessed by a simple growth inhibition test using Bacillus subtilis as the study object,and the hydrophilic property was proved by a water contact angle measurement.

关键词： β-cyclodextrin Co-precipitation Encapsulation efficiency Microcapsule Tea tree oil