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Incidental Uptake of In-111 Ibritumomab Tiuxetan in Surgically Treated Fracture

Advances in Molecular Imaging 2011年第1期1卷 12-15页

作者： hidenari hirata Makoto Nakagawa Koichiro Abe Takashi Okafuji Kenji Shinozaki Ilseung Choi Naokuni Uike Shuji Sakai Department of Clinical Radiology Graduate School of Medical Sciences Kyushu University Department of Hematology National Kyushu Cancer Center Fukuoka Japan Department of Radiology National Kyushu Cancer Center Fukuoka Japan

In-111 ibritumomab tiuxetan pretherapy imaging is performed prior to radioimmunotherapy with Y-90 ibritumomab tiuxetan in patients with lymphoma in order to estimate the biodistribution of the radiolabeled antibodies. We report the case of a 61-year-old woman with relapsed follicular lymphoma. In-111 ibritumomab tiuxetan pretherapy imaging showed tracer accumulation in a surgically treated fracture of the left calcaneus as well as in the involved lesions. The patient had fractured her left calcaneus 6 months before the radioimmunotherapy, and fracture of the left calcaneus without lymphoma involvement had been revealed operatively at that time. Clinical features and magnetic resonance imaging (MRI) indicated an inflammatory response in the left heel. We concluded that this inflammation played an important role in the uptake on pretherapy imaging. It should be kept in mind that the inflammation is a differential diagnosis of lymphoma involvement in In-111 ibritumomab tiuxetan pretherapy imaging. To the best of our knowledge, this is the first case report of In-111 ibritumomab tiuxetan uptake in a surgically treated fracture.

关键词： In-111 Ibritumomab Fracture Lymphoma

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The Effect of Treatment Position on Rectal and Bladder Dose-Volume Histograms for Prostate Radiotherapy Planned with 3-Dimensional Conformal Radiotherapy, Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2014年第2期3卷 88-97页

作者： Kotaro Terashima Katsumasa Nakamura Tomonari Sasaki Saiji Ohga Tadamasa Yoshitake Kazushige Atsumi Makoto Shinoto Kaori Asai Keiji Matsumoto hidenari hirata Yoshiyuki Shioyama Akihiro Nishie Hiroshi Honda Department of Clinical Radiology Graduate School of Medical Sciences Kyushu University Fukuoka Japan Department of Radiology Kyushu University Hospital at Beppu Beppu Japan Kyushu International Heavy Ion Beam Therapy Center Tosu Saga Japan

Purpose: To compare target coverage and organ at risk (OAR) sparing in the supine and prone positions with 3-dimensional conformal radiotherapy (3DCRT), intensity-modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) in low- and high-risk prostate radiotherapy cases. Materials and Methods: Using magnetic resonance images of five healthy volunteers, six treatment plans (supine 3DCRT, prone 3DCRT, supine IMRT, prone IMRT, supine VMAT and prone VMAT) were generated. Planning target volume 1 (PTV1) was defined as the prostate gland plus the seminal vesicles with adequate margins in a high-risk setting, while PTV2 was defined as prostate only with margins in a low-risk setting. The mean dose for both PTV1 and PTV2 was set at 78 Gy. Plans generated by each of the 3 techniques were compared between the supine and prone positions using dose-volume histograms (DVHs). Results: For PTV1, prone 3DCRT provided a significantly higher D98% than did supine 3DCRT, and its homogeneity index (HI) was significantly better. IMRT and VMAT values did not differ significantly between the prone and supine positions. For PTV2, no values differed significantly between the supine and prone positions under any treatment plan. With respect to OAR, the rectal D mean, D2%, V50, and V60 values of PTV1 were statistically higher in supine 3DCRT than in prone 3DCRT, while there were no significant differences in rectal values between the supine and prone positions with IMRT or VMAT. The rectal Dmean, V50, V60, V70, and V75 values of prone 3DCRT were significantly higher than those of supine IMRT or supine VMAT. There were no significant differences in any values for the rectum and bladder for PTV2. Conclusion: Although prone 3DCRT was found to be superior to supine 3DCRT in terms of rectal sparing in high-risk prostate cancer, IMRT and VMAT techniques could possibly cover this disadvantage.

关键词： Prostate Radiotherapy Dosimetric Comparison 3DCRT IMRT VMAT

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Resolution of epidural hematoma related to osteoporotic fracture after percutaneous vertebroplasty

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World Journal of Radiology 2013年第8期5卷 325-327页

作者： hidenari hirata Akio Hiwatashi Takashi Yoshiura Osamu Togao Koji Yamashita Hironori Kamano Kazufumi Kikuchi Hiroshi Honda Department of Clinical Radiology Graduate School of Medical SciencesKyushu University

We are the first to report a case that showed spontaneous resolution of epidural hematoma which was related to a steroid-induced osteoporotic compression *** patient had a painful fracture with an intravertebral cleft at L1 accompanying an epidural hematoma *** pain relief was achieved after percutaneous *** resolution of hematoma was noted three months after *** theorized that intravertebral stability after treatment might have played a role in this patient.

关键词： Vertebroplasty Osteoporosis Epidural hematoma Spinal canal compromise Intravertebral cleft

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