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An Experimental Study on Response and Control of a Flapping-Wing Aerial Robot Under Wind Gusts

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Journal of Bionic Engineering 2024年第1期21卷 209-223页

作者： Kazuki shimura Hikaru Aono Chang-kwon Kang Graduate School of Science and Technology Shinshu University3-15-1 TokidaUedaNagano 3868567Japan Department of Mechanical Engineering and Robotics 3-15-1 TokidaUedaNagano 3868567Japan Department of Mechanical and Aerospace Engineering University of Alabama in HuntsvilleTechnology Hall N266HuntsvilleAL35899USA

Bioinspired flapping-wing micro-air-vehicles(FWMAVs)have the potential to be useful aerial tools for gathering information in various *** recent advancements in manufacturing technologies and better understanding of aerodynamic mechanisms behind of the flapping flight,outdoor flights have become a ***,to fully realize the potential of FWMAVs,further improvements are necessary,particularly in terms of stability and robustness under gusty *** this study,the response and control of a tailless two-winged FWMAV under the wind gusts are *** experiments are conducted with a one-degree-of-freedom gimbal to focus on effects of wind gusts on the rotational motion of the ***-derivative and sliding-mode controls are adopted for the attitude *** present that the body angles changed in time and reached approximately 50°at the maximum due to the wing *** sliding-mode controller can more effectively control the rotational angle in the presence of disturbances and both the wing speed and changes in wind speed have an impact on the effectiveness of attitude *** results contribute to the development of of tailless two-winged,single-motor driven FWMAVs in terms of the design of attitude controller and testing apparatus.

关键词： Flapping-wing micro-air vehicles Sliding-mode control Pitch and roll angle-Wind gus

Case of autoimmune hepatitis with markedly enlarged hepatoduodenal ligament lymph nodes

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World Journal of Gastroenterology 2013年第11期19卷 1834-1840页

作者： hideki Fujii Naoki Ohnishi Kazuho shimura Masafumi Sakamoto Tohru Ohkawara Yoshihiko Sawa Koichi Nishida Yasuo Ohkawara Tatsuro Kobata Kanji Yamaguchi Yoshito Itoh Department of Internal Medicine Aiseikai Yamashina HospitalShichouno-choTakehanaYamashinakuKyoto 602-8086Japan Department of Gastroenterology and Hepatology Uji Tokushukai HospitalKyoto 611-0042Japan Molecular Gastroenterology and Hepatology Kyoto Prefectural University of MedicineGraduate School of Medical ScienceKyoto 602-8566Japan

Autoimmune hepatitis(AIH) is a necroinflammatory liver disease of unknown *** disease is characterized histologically by interface hepatitis,biochemically by increased aspartate aminotransferase and alanine aminotransferase levels,and serologically by increased autoantibodies and immunoglobulin G *** we discuss AIH in a previously healthy 37-year-old male with highly elevated serum levels of soluble interleukin-2 receptor and markedly enlarged hepatoduodenal ligament lymph nodes(HLLNs,diameter,50 mm).Based on these observations,the differential diagnoses were AIH,lymphoma,or Castleman's *** biopsy revealed the features of interface hepatitis without bridging fibrosis along with plasma cell infiltration which is the typical characteristics of acute *** node biopsy revealed lymphoid follicles with inflammatory lymphocytic infiltration;immunohistochemical examination excluded the presence of lymphoma ***,he was administered corticosteroid therapy:after 2 mo,the enlarged liver reached an almost normal size and the enlarged HLLNs reduced in *** could not find AIH cases with such enlarged lymph nodes(diameter,50 mm) in our literature ***,we speculate that markedly enlarged lymph nodes observed in our patient may be caused by a highly activated,humoral immune response in AIH.

关键词： Autoimmune hepatitis Humoral immune response Hepatoduodenal ligament lymph nodes Corticosteroid Hepatomegaly

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World Journal of Gastroenterology 2006年第11期12卷 1805-1809页

作者： Yoshimi Nakajima Hitoshi Takagi Naondo Sohara Ken Sato Satoru Kakizaki Kenichi Nomoto hideki Suzuki Taketoshi Suehiro Tatsuo shimura Takayuki Asao Hiroyuki Kuwano Masatomo Mori Ken Nishikura Department of Medicine and Molecular Science Gunma University Graduate School of Medicine MaebashiGunma 371-8511Japan Department of Surgery Gunma University Graduate School of Medicine MaebashiGunma 371-8511Japan Division of Molecular and Functional Pathology Department of Cellular Function Niigata University Graduate School of Medicine and Dental SciencesNiigataNiigata 951-8510Japan

A 42-year-old woman was admitted to our hospital because of multiple liver tumors detected by ultrasonography. Colonoscopy revealed submucosal tumor in the rectum, which was considered the primary lesion. Endoscopic mucosal resection followed by histopathological examination revealed that the tumor was carcinoid. The resected margin of the tumor was positive for malignant cells. Two courses to transcatheter arterial chemotherapy for liver metastasis were ineffective. Accordingly, the rectal tumor and metastatic lymph nodes were surgically resected. One month after the operation, she received liver transplantation （left lateral segment and caudate lobe） from her son. No recurrent lesion has been observed at two years after the liver transplantation. Liver transplantation should be considered as a treatment option even in advanced case of carcinoid metastasis to the liver. We also discuss the literature on liver transplantation for metastatic carcinoid tumor.

关键词： Carcinoid Liver metastasis Living related liver transplantation

Inflammatory pseudotumor of the liver and peripheral eosinophilia in autoimmune pancreatitis

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World Journal of Gastroenterology 2005年第6期11卷 922-925页

作者： Naoki Sasahira Takao Kawabe Akira Nakamura Kenji shimura Haruhisa shimura Ei Itobayashi Manabu Asada Yasushi Shiratori Masao Omata Department of Gastroenterology

AIM: Inflammatory pseudotumor (IPT) of the liver is a rare benign lesion, the etiology of which remains *** is not associated with any particular diseases apart from phlebitis and Crohn's ***: A middle-aged male with hepatic IPT and peripheral eosinophilia associated with autoimmune pancreatitis (AIP) was selected for this study and review of ***: A 59-year-old male was admitted with obstructive jaundice, marked eosinophilia (1 343/mm3)and hypergammaglobulinemia (4 145 mg/dL). Imaging techniques revealed dilatation of the intrahepatic bile duct,stenosis of the common bile duct with diffuse wall thickening, gallbladder wall thickening, irregular narrowing of the pancreatic duct, and swelling of the pancreatic parenchyma. Multiple liver masses were also demonstrated and diagnosed as IPT by biopsy specimens. Six months later, the abnormal features of the biliary tree remarkably improved by the oral administration of prednisolone, and the liver masses disappeared. The swelling of the pancreatic head also improved. The peripheral eosinophil count normalized. IPT associated with AIP, as we know,has not been reported in the literature. The clinical features of the present case mimicked those of pancreatic cancer with liver metastasis. This case deserves to be documented to prevent misdiagnosis of similar cases.

关键词： Inflammatory pseudotumor Autoimmune pancreatitis

Hyperbaric oxygenation promotes regeneration of biliary cells and improves cholestasis in rats

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World Journal of Gastroenterology 2011年第17期17卷 2229-2235页

作者： Akihito Idetsu Taketoshi Suehiro Kohji Okada Tatsuo shimura Hiroyuki Kuwano Department of General Surgical Science Gunma University Graduate School of Medicine 3-39-22 Showamachi Maebashi Gunma 371-8511 Japan

AIM:To investigate the effects of hyperbaric oxygenation(HBO) on regeneration of the biliary ductal system and postoperative cholestasis in hepatectomized ***:HBO was performed in Wistar rats daily starting 12 h after a 70% partial *** liver weight,serum parameters and the proliferating cell nuclear antigen labeling index of hepatocytes and biliary ductal cells were *** growth factor(HGF),c-Met and transforming growth factor(TGF) β-1 mRNA expression levels were analyzed by quantitative reverse transcription polymerase chain ***:HBO improved the postoperative serum levels of total bile acid but not transaminase *** promoted hepatocyte and biliary ductal cell *** hematoxylin and eosin-stained specimens revealed fewer ballooned hepatocytes and higher cell densities in the HBO group compared to the control *** suppressed c-Met mRNA levels at 15 h but did not modulate HGF or TGF β-1 mRNA expression levels.

关键词： Hyperbaric oxygenation Liver regeneration Partial hepatectomy Cholestasis Ballooning

Readout Properties of Polychromatic Reconstruction for Nondestructive Holographic Data Storage

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红外与激光工程 2016年第9期45卷 36-42页

作者： Ryushi Fujimura Tsutomu shimura Kazuo Kuroda Department of Optical Engineering Utsunomiya University Center for Optical Research and Education Utsunomiya University Institute of Industrial Science The University of Tokyo

Polychromatic reconstruction(PCR) is a novel nondestructive readout method that utilizes a spectrally broad light source for the probe beam. The stored image can be completely reconstructed even though the probe wavelength is very different from the recording one. The large spectral width of the polychromatic probe beam also causes adverse effect on the storage density. But this can be overcomed if an additional optical component is inserted in the imaging system. Therefore, PCR has a great potential to achieve nondestructive readout and large storage density simultaneously. In addition, PCR enables us to design a simple memory system because its readout tolerance is quite large as compared to the conventional monochromatic readout. Unique and attractive features of the polychromatic reconstruction method was theoretically and experimentally demonstrated.

关键词：激光雷达成像仿真空间目标在轨

Method of Searching for Earthquake Disaster Evacuation Routes Using Multi-Objective GA and GIS

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Journal of Geographic Information System 2014年第5期6卷 492-525页

作者： Yuichiro shimura Kayoko Yamamoto Graduate School of Information Systems University of Electro-Communications Tokyo Japan

This study treats the determination of routes for evacuation on foot in earthquake disasters as a multi-objective optimization problem, and aims to propose a method for quantitatively searching for evacuation routes using a multi-objective genetic algorithm (multi-objective GA) and GIS. The conclusions can be summarized in the following three points. 1) A GA was used to design and create an evacuation route search algorithm which solves the problem of the optimization of earthquake disaster evacuation routes by treating it as an optimization problem with multiple objectives, such as evacuation distance and evacuation time. 2) In this method, goodness of fit is set by using a Pareto ranking method to determine the ranking of individuals based on their relative superiorities and inferiorities. 3) In this method, searching for evacuation routes based on the information on present conditions allows evacuation routes to be derived based on present building and road locations.?Further, this method is based on publicly available information;therefore, obtaining geographic information similar to that of this study enables this method to be effective regardless of what region it is applied to, or whether the data regards the past or the future. Therefore, this method has high degree of spatial and temporal reproducibility.

关键词： Evacuation Route Evacuation Site Earthquake Disaster Multi-Objective Optimization Problem Multi-Objective GA (Multi-Objective Genetic Algorithm) Pareto Ranking Method GIS

Increase in serum levels of phosphatidylserine-specific phospholipase A_(1) in COVID-19 patients

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Cellular & Molecular Immunology 2021年第9期18卷 2275-2277页

作者： Takuya shimura Makoto Kurano Koh Okamoto Daisuke Jubishi Kuniyuki Kano Koji Igarashi Satoshi Shimamoto Junken Aoki Kyoji Moriya Yutaka Yatomi Department of Clinical Laboratory The University of Tokyo HospitalTokyoJapan Department of Clinical Laboratory Medicine Graduate School of MedicineThe University of TokyoTokyoJapan Department of Infectious Diseases The University of Tokyo HospitalTokyoJapan Department of Health Chemistry Graduate School of Pharmaceutical SciencesThe University of TokyoTokyoJapan Bioscience Division TOSOH CorporationKanagawaJapan

The development of novel drugs to overcome the current global coronavirus disease 2019(COVID-19)pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is an important *** antiviral agents have been investigated,one of the important goals of treatment is also to control the biological response to the infection.A series of elegant basic studies have revealed that lysophosphatidylserine(LysoPS)might play important roles in inflammation through three kinds of G protein-coupled receptors[1];LysoPS reportedly suppresses activation of T cells[2]and secretion of inflammatory cytokines from macrophages[3]and promotes phagocytosis of apoptotic cells,including apoptotic neutrophils,by macrophages[4].

关键词： drugs inflammation acute

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GRIMSEL现场的气体渗透试验(英文)

岩石力学与工程学报 2006年第4期25卷 781-787页

作者： Fujiwara A Okamoto S Tsuboya T Vomvoris S Marschall P Ando K shimura T 放射性废弃物管理基金会与研究中心(RWMC) 放射性废弃物处置公司(Nagra) Obayashi Corporation

自 1976 年以来,日本核废料管理基金会与研究中心(RWMC)一直在进行核废料处置的研究。最近,RWMC非常关注核废料处置库的监测、遥控以及现场勘查技术等重要的社会公众与技术问题。其中,处置库溢出气体是一项重要的安全可靠性评估项目。... 详细信息

自 1976 年以来,日本核废料管理基金会与研究中心(RWMC)一直在进行核废料处置的研究。最近,RWMC非常关注核废料处置库的监测、遥控以及现场勘查技术等重要的社会公众与技术问题。其中,处置库溢出气体是一项重要的安全可靠性评估项目。这项名为“工程屏障的气体渗透试验”(GMT)的研究是在瑞士 Nagra 的 Grimsel现场实验室进行的。GMT 集中研究在粮仓形的处置库中由核废料产生的气体在工程屏障中的渗透问题。在 Grimsel现场,一个按比例缩小的工程屏障库由一个具有透气孔的混凝土仓和砂–膨润土缓冲材料组成,缓冲材料被放置在一个专门建造的洞室中。混凝土仓直径为 2.5 m,高为 2.5 m,放置在直径为 4 m 的从上到下开挖而成的竖井中。在工程屏障饱和及水渗透试验之后,气体分两个阶段被注入地窖中。气体第一次被注入之后,重复进行水渗透试验,以便观察工程屏障库的变化。第二次气体注入的时候,在工程屏障及岩石圈中采用一种可以多点取样的鸡尾酒气体跟踪器。在气体注入之后,小心挖掘出工程屏障库,然后用各种方法来进行鉴定,并采用实验室以及建模程序来进行现场的模拟研究。

关键词：放射性废物处置超铀废物原位试验工程屏障体系气体渗透两相流模拟