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SnO-SnO_(2) modified two-dimensional MXene Ti3C2Tx for acetone gas sensor working at room temperature

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Journal of Materials Science & Technology 2021年第14期73卷 128-138页

作者： Zijing Wang Fen Wang Angga Hermawan Yusuke Asakura Takuya hasegawa Hiromu Kumagai hideki Kato Masato Kakihana Jianfeng Zhu Shu Yin School of Material Science and Engineering Shaanxi Key Laboratory of Green Preparation and Functionalization for Inorganic MaterialsShaanxi University of Science and TechnologyXi'an710021China Institute of Multidisciplinary Research for Advanced Materials Tohoku UniversitySendai980-8577Japan The Institute of Scientific and Industrial Research(ISIR) Osaka University Mihogaoka 8-1IbarakiOsaka567-0047Japan

Acetone,as widely used reagents in industry and laboratories,are extremely harmful to the human.So the detection of acetone gas concentrations and leaks in special environments at room temperature is essential.Herein,the nanocomposite combining SnO-SnO_(2)(p-n junction)and Ti_(3)C_(2)T_(x) MXene was successfully synthesized by a one-step hydrothermal method.Because of the existence of a small amount of oxygen during the hydrothermal conditions,part of the p-type SnO was oxidized to n-type SnO_(2),forming in-situ p-n junctions on the surface of Sn O.The hamburger-like SnO-SnO_(2)/Ti_(3)C_(2)T_(x) sensor exhibited improved acetone gas sensing response of 12.1(R_(g)/R_(a))at room temperature,which were nearly 11 and 4 times higher than those of pristine Ti_(3)C_(2)T_(x) and pristine SnO-SnO_(2),respectively.Moreover,it expressed a short recovery time(9 s)and outstanding reproducibility.Because of the different work functions,the Schottky barrier was formed between the SnO and the Ti_(3)C_(2)T_(x) nanosheets,acting as a hole accumulation layer(HALs)between Ti_(3)C_(2)T_(x) and tin oxides.Herein,the sensing mechanism based on the formation of hetero-junctions and high conductivity of the metallic phase of Ti_(3)C_(2)T_(x) MXene in SnO-SnO_(2)/Ti_(3)C_(2)T_(x) sensors was discussed in detail.

关键词： p-n junction Ti_(3)C_(2)T_(x)MXene Nanocomposites Acetone gas sensor Room temperature sensing

Different Starting Dominant Strain of Seasonal Influenza in China and Other Neighboring Asian Countries in 2019−2020 Winter Season

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China CDC weekly 2020年第4期2卷 57-60页

作者： Jing Yang Weijuan Huang Yanhui Cheng Tao Chen Minju Tan Qian Guo Hejiang Wei Fei Zhu Tomoko Kuwahara Xiyan Li Xiang Zhao Hideki Hasegawa George F.Gao Dayan Wang National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and PreventionWHO Collaborating Center for Reference and Research on InfluenzaKey Laboratory for Medical VirologyNational Health CommissionBeijingChina Laboratory of Influenza Virus Surveillance Influenza Virus Research CenterNational Institute of Infectious DiseasesWHO Collaborating Center for Reference and Research on InfluenzaTokyoJapan Chinese Center for Disease Control and Prevention BeijingChina.

Introduction:Seasonal influenza is a prevalent and highly contagious acute respiratory disease that causes a major global disease burden.New strains of influenza viruses also have the potential to cause an influenza pandemic.Due to the high variability and the consequent uncertainty about virus strains,the prevention and control of influenza are faced with many challenges.Surveillance is considered a key strategy to lead to the prevention and control of influenza,and influenza is one of first infectious diseases to be monitored globally.Methods:The Chinese National Influenza Surveillance Network conducts routine influenza surveillance and includes 410 network laboratories and 554 sentinel hospitals based on the requirements of National Influenza Surveillance Guidelines.China and other countries submit epidemiological and virological data to the WHO FluMart database,which can be viewed online.Results:Seasonal influenza H3N2 virus was the dominant subtype in China when entering the 2019–2020 winter influenza season,while neighboring countries such as Japan and Republic of Korea reported the dominance of H1N1pdm09 and Mongolia and Russia reported a higher proportion of type B virus than type A virus.Conclusions and Implications for Public Health Practice:Asian countries entered the 2019–2020 winter influenza season with different type/subtypes of influenza virus dominant in different areas.Influenza surveillance needs to be strengthened to closely monitor changes in the antigenicity and genetic characteristics of emerging viruses.

关键词： prevention strengthened submit

Development of highly sensitive and rapid antigen detection assay for diagnosis of COVID-19 utilizing optical waveguide immunosensor

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Journal of Molecular Cell Biology 2021年第10期13卷 763-766页

作者： Rikako Funabashi Kei Miyakawa Yutaro Yamaoka Seiko Yoshimura Satoshi Yamane Sundararaj Stanleyraj Jeremiah Kohei Shimizu Hiroki Ozawa Chiharu Kawakami Shuzo Usuku Nobuko Tanaka Etsuko Yamazaki Hirokazu Kimura Hideki Hasegawa Akihide Ryo Department of Microbiology Yokohama City University Graduate School of MedicineKanagawajapan Life Science Laboratory Technology and Development DivisionKanto Chemical Co.Inc.KanagawaJapan Primary Care Testing Solution Development Department Canon Medical Systems CorporationTochigiJapan Yokohama City Institute of Public Health KanagawaJapan Clinical Laboratory Department Yokohama City University HospitalKanagawaJapan Department of Health Science Gunma Paz University Graduate SchoolGunmajapan Center for Influenza and Respiratory Virus Research National Institute of Infectious DiseasesMusashimurayamaTokyoJapan

Ever since its outbreak,the COVID-19 pandemic caused by SARS-CoV-2 has been spreading rapidly causing a global health crisis.Accurate diagnosis and instituting appropriate intervention to relevant individuals are essential not only to slow down the spread of this pandemic but also to manage our resources efficiently.To date,testing for SARS-CoV-2 infection mostly relies on reverse transcription-quantitative polymerase chain reaction(RT-qPCR)on a nasopharyngeal or saliva specimen and remains the gold standard for diagnosis as it exhibits high sensitivity and specificity.

关键词： diagnosis specificity nasopharyngeal

H_∞Loop Shaping Control for Plasma Vertical Position Instability on QUEST

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Plasma Science and Technology 2013年第3期15卷 295-299页

作者：刘晓龙 Kazuo NAKAMURA Tatsuya YOSHISUE Osamu MITARAI Makoto hasegawa Kazutoshi TOKUNAGA 薛二兵 hideki ZUSHI Kazuaki HANADA Akihide FUJISAWA Hiroshi IDEI Shoji KAWASAKI Hisatoshi NAKASHIMA Aki HIGASHIJIMA Kuniaki ARAKI IGSES Kyushu University RIAM Kyushu University Tokai University

QUEST has a divertor configuration with a high and a negative n-index, and the problem of plasma vertical position instability control in QUEST is still under extensive study for achieving high efficiency plasma. The instability we considered is that the toroidal plasma moves either up or down in the vacuum chamber until it meets the vessel wall and is extinguished. The actively controlled coils （HCU and HCL） outside the vacuum vessel are serially connected in feedback with a measurement of the plasma vertical position to provide stabilizing control. In this work, a robust controller is employed by using the loop synthesis method, and provides robust stability over a wide range of n-index. Moreover, the gain of the robust controller is lower than that of a typical proportional derivative （PD） controller in the operational frequency range; it indicates that the robust controller needs less power consumption than the PD controller does.

关键词： vertical position instability robust control loop shaping QUEST

Retinal ganglion cell protection by hop-flower extract as a novel neuroprotective strategy for glaucoma

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Neural Regeneration Research 2022年第6期17卷 1267-1268页

作者： Tomoko hasegawa Hanako Ohashi Ikeda Department of Ophthalmology and Visual Sciences Kyoto University Graduate School of MedicineKyotoJapan Research Fellow of Japan Society for the Promotion of Science TokyoJapan

In glaucoma,a leading cause of blindness,retinal ganglion cells are progressively damaged.Intraocular pressure reduction is the only established treatment for glaucoma(Collaborative Normal-Tension Glaucoma Study Group,1998;Vass et al.,2007).However,in some cases,visual field loss progresses despite sufficiently reduced intraocular pressure(Collaborative Normal-Tension Glaucoma Study Group,1998;Killer and Pircher,2018).While intraocular pressure and age are known risk factors for glaucoma(Ernest et al.,2013),the underlying mechanisms of glaucoma progression are not fully understood.

关键词： glaucoma al. protective

Complex-Valued Neural Networks:A Comprehensive Survey

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IEEE/CAA Journal of Automatica Sinica 2022年第8期9卷 1406-1426页

作者： ChiYan Lee Hideyuki hasegawa Shangce Gao Faculty of Engineering University of ToyamaToyama 930-8555Japan

Complex-valued neural networks(CVNNs)have shown their excellent efficiency compared to their real counterparts in speech enhancement,image and signal processing.Researchers throughout the years have made many efforts to improve the learning algorithms and activation functions of CVNNs.Since CVNNs have proven to have better performance in handling the naturally complex-valued data and signals,this area of study will grow and expect the arrival of some effective improvements in the future.Therefore,there exists an obvious reason to provide a comprehensive survey paper that systematically collects and categorizes the advancement of CVNNs.In this paper,we discuss and summarize the recent advances based on their learning algorithms,activation functions,which is the most challenging part of building a CVNN,and applications.Besides,we outline the structure and applications of complex-valued convolutional,residual and recurrent neural networks.Finally,we also present some challenges and future research directions to facilitate the exploration of the ability of CVNNs.

关键词： Complex activation function complex backpropagation algorithm complex-valued learning algorithm complex-valued neural network deep learning

Expression of Acetaldehyde Dehydrogenase Gene Increases Hydrogen Production and Acetate Consumption by <i>Rhodobacter sphaeroides</i>

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Energy and Power Engineering 2015年第9期7卷 396-402页

作者： Shinya hasegawa Jyumpei Kobayashi Tomoe Komoriya hideki Kohno Kazuaki Yoshimune Department of Applied Molecular Chemistry Graduate School of Industrial Technology Nihon University Narashino Chiba Japan Microbial Genetic Division Institute of Genetic Resources Faculty of Agriculture Kyushu University Fukuoka Japan Department of Sustainable Engineering College of Industrial Technology Nihon University Narashino Chiba Japan

Rhodobacter sphaeroides RV (RV) produces high yields of hydrogen from organic acids in the presence of light. The hydrogen production from acetate is lower than that from lactate, probably because of its low ability to metabolize acetate. In this study, gene of acetaldehyde dehydrogenase (ACDH, EC 1.***.1.10) that catalyzes the reversible conversion of acetaldehyde and CoA to acetyl-CoA with the concurrent reduction of NAD to NADH, is overexpressed in the RV strain. The produced acetyl-CoA can be oxidized to carbon dioxide in the tricarboxylic acid (TCA) cycle, wherein electrons are generated and used for hydrogen production. The byproduct NADH can be used as reducing agent for acetate to produce acetaldehyde by acetate dehydrogenase. The recombinant RV strain (RVAC) expressing the ACDH gene showed ACDH activity with a specific activity of 3.2 mU/ mg, and the RV and the recombinant RV strain that harbored the intact (empty) plasmid pLP-1.2 (RVI) showed no detectable ACDH activity. The hydrogen yields of the RVAC strain from 21-mM acetate were 1.5-fold higher than that of the wild type RV strain and also that of the RVI strain. In contrast, hydrogen yield from 21-mM lactate was 30% lower than that in the control strains.

关键词： Acetate Lactate Photosynthetic Bacteria Rhodobacter sphaeroides Aldehyde Dehydrogenase

Adenosine triphosphate maintenance by branched chain amino acids as a novel neuroprotective strategy for retinal neurodegenerative diseases

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Neural Regeneration Research 2019年第1期14卷 82-84页

作者： Tomoko hasegawa Hanako Ohashi Ikeda Department of Ophthalmology and Visual Sciences Kyoto University Graduate School of Medicine Department of Experimental Therapeutics Institute for Advancement of Clinical and Translational Science Kyoto University Hospital

Retinal neuronal cell death is caused in many incurable eye diseases such as retinitis pigmentosa(RP)and glaucoma,which are leading causes of adult blindness.In RP,progressive loss of photoreceptor cells leads to visual disturbance.No established treatments are available to date for this condition,although potential treatments,including regenerative medicine,gene therapy,and neurotropic factor therapy are being investigated.In glaucoma。

关键词：眼睛疾病视网膜氨基酸基因治疗腺苷分叉维护光敏电阻器

Dendritic Learning-Incorporated Vision Transformer for Image Recognition

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IEEE/CAA Journal of Automatica Sinica 2024年第2期11卷 539-541页

作者： Zhiming Zhang Zhenyu Lei Masaaki Omura Hideyuki hasegawa Shangce Gao Faculty of Engineering University of ToyamaToyama-shi 930-8555Japan IEEE

Dear Editor,This letter proposes to integrate dendritic learnable network architecture with Vision Transformer to improve the accuracy of image recognition.In this study,based on the theory of dendritic neurons in neuroscience,we design a network that is more practical for engineering to classify visual features.Based on this,we propose a dendritic learning-incorporated vision Transformer(DVT),which out-performs other state-of-the-art methods on three image recognition benchmarks.

关键词： Image network image