检索结果-南通市图书馆

肝癌高发区不同饮用水类型中微囊藻毒素含量调查

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

中华预防医学杂志 1996年第1期30卷 6-9页

作者：陈刚俞顺章卫国荣陈公超徐小英黄裕华 Ken-ichi harada Yoshio Ueno 上海医科大学流行病学教研室江苏省海门市卫生防疫站日本名城大学日本东京理科大学

为了解肝脏促癌剂微囊藻毒素（ＭＣ）在肝癌高发区饮用水中的污染情况，于１９９２至１９９３年对江苏海门居民饮用水中藻类及其产生的ＭＣ进行了检测，经鉴定在海门沟河水中颤藻是目前已被证明能产生ＭＣ的最常见的藻属；在６５个水样... 详细信息

为了解肝脏促癌剂微囊藻毒素（ＭＣ）在肝癌高发区饮用水中的污染情况，于１９９２至１９９３年对江苏海门居民饮用水中藻类及其产生的ＭＣ进行了检测，经鉴定在海门沟河水中颤藻是目前已被证明能产生ＭＣ的最常见的藻属；在６５个水样中有２份经高效液相和液相色谱／质谱分析确定含有ＭＣ。进一步于１９９４年７月在江苏海门采集不同饮用水源共９８９份，采用高敏感度酶联免疫方法测定ＭＣ含量。结果在沟塘水、河水、浅井水和深井水中ＭＣ的阳性率（＞５０ｐｇ／ｍｌ）分别为１７．３％，３１．９％，４．３％，０．０％；阳性样本中ＭＣ平均含量分别为１０１，１６０，６８，０。在沟塘水和河水中ＭＣ的阳性率和阳性样本中的平均含量均显著大于浅井水和深井水，提示应对饮用水中ＭＣ与肝癌的关系作进一步研究。

关键词：肝肿瘤饮水微囊藻毒素

76例淋巴瘤样胃病的临床病理分析：扩展该疾病的谱系到CD4-CD8＋的病例

在线全文

学校读者我要写书评

暂无评论

临床与实验病理学杂志 2015年第11期31卷 1227-1227页

作者： Takata K Noujima-harada M Miyata-Takata T 魏建国刘勇不详浙江省绍兴市人民医院病理科绍兴312000 江西省人民医院病理科南昌330006

淋巴瘤样胃病于2010年首次报道，是一种罕见的、病因未知的NK细胞增生性疾病，免疫组化标记为CD3＋CD4-CD5-CD8-CD56＋。由于组织病理学与恶性淋巴瘤具有相似性，诊断极具挑战性。

关键词：细胞增生性疾病淋巴瘤样病理分析胃病病例谱系临床免疫组化标记

在线全文

学校读者我要写书评

暂无评论

水-空(水冷式)进气中冷器的开发

汽车与新动力 2018年第1期1卷 44-47页

作者： M.harada T.Yasuda S.Terachi S.Pujols J.R.Spenny 陈佳

随着强调环境友好型社会的发展趋势,发动机的机械增压化和小型化正在普及。介绍了高性能和高质量的水-空进气中冷器的开发。为了达到更高的冷却性能,开发的水-空进气中冷器优化了翅片、管子和芯子矩阵,从而使其具有更高性能和更轻质量... 详细信息

随着强调环境友好型社会的发展趋势,发动机的机械增压化和小型化正在普及。介绍了高性能和高质量的水-空进气中冷器的开发。为了达到更高的冷却性能,开发的水-空进气中冷器优化了翅片、管子和芯子矩阵,从而使其具有更高性能和更轻质量。为了在热应力下具有更高的可靠性,基于瞬态分析和仿真技术确定了水-空进气中冷器的详细参数。

关键词：水-空进气中冷器均质化模型热应力仿真

Seven microcystins from Microcystis waterbloom in Lake Dalai,China

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 1997年第1期9卷 113-119页

作者： He Zhenrong He Jiawan Yu Minjuan Institute of Hydrobiology,Chinese Academy of Sciences,Wuhan 430072,ChinaQiao Mingye Shen Zhi Wu Liandi Inner Mongolia Environmental Science Research Instìtute,Huhehote 010010,ChinaWu Suozhu Guo Yunfeng Hulunbeer League Environmental Monitoring Station,Inner Mogolia 021008,ChinaFumio Kondo Aichi Prefectural Institute of Public Health,Tsuji-machi,Kita-ku,Nagoya 462,JapanKen-ichi harada Faculty of Pharmacy,Meijo University,Tempaku,Nagoya 468,Japan Institute of Hydrobiology Chinese Academy of Sciences Wuhan 430072 China Inner Mongolia Environ. Sci. Res. I. Huhehote 010010 China Hulunbeer League Environ. M.S. Inner Mogolia 021008 China Aichi Pref. Inst. of Public Health Tsuji-machi Kita-ku Nagoya 462 Japan Faculty of Pharmacy Meijo University Tempaku Nagoya 468 Japan

Seven types of microcystins,isolated from Microcystis waterbloom in Lake Dalai, were *** major toxins:MCYST-LR,MCYST-RR,[D-Asp^3]MCYST-LR and [Dha^7]MCYST-LR were identified by high performance liquid chromatography(HPLC),as com- pared with the authentic *** minor toxins:MCYST FR,[L-Mser^7]MCYST-LR and an unknown MCYST which was most likely to be MCYST-(H_4)YR were identified with frit- fast atom bombardment liquid chromatography/mass spectrometry(Frit-FAB LC/MS)and amino acid *** toxigenic diversity in blue-green algae(cyanobacteria)was discussed.

关键词： microcystin cyanobacteria waterbloom identification Frit-FAB LC/MS.

广东省二种兽类新纪录—鼩猬(Neotetracus sinensis)和短尾鼩(Anourosorex squamipes)

在线全文

学校读者我要写书评

暂无评论

兽类学报 2011年第3期31卷 317-319页

作者：吴毅本川雅治李玉春龚粤宁新宅勇太原田正史广州大学华南生物多样性保护与利用重点实验室广州510006 京都大学综合博物馆山东大学威海分校海洋学院威海264209 南岭国家级自然保护区韶关512700 京都大学理学研究科大阪市立大学医学部动物实验中心

2009年9月,在广东省南岭国家级自然保护区石坑崆（24°55＇7″N,112°59＇4″E;海拔1831～1895m）进行动物考察时采集到一批兽类标本。经鉴定,其中鼩猬（Neotetracus

关键词：鼩猬短尾鼩新纪录

256层螺旋CT低剂量对比剂低管电压高管电流扫描方案在肾功能衰竭病人腹部动态增强扫描中的临床应用

在线全文

学校读者我要写书评

暂无评论

国际医学放射学杂志 2012年第1期 72-73页

作者： T.Nakaura K.Awai N.Maruyama N.Takata I.Yoshinaka K.harada 李琼 Department of Diagnostic Radiology Amakusa Medical CenterKameba 854-1AmakusaKumamoto 863-0046Japan

目的探讨256层螺旋CT低剂量对比剂低管电压高管电流腹部动态增强扫描方案的临床应用的可行性。材料与方法本前瞻性研究获机构审查委员会批准,并获得了病人的知情同意书。此研究共纳入151例病人,其中估算肾小球滤过率(eGFR)大于或等于60m... 详细信息

目的探讨256层螺旋CT低剂量对比剂低管电压高管电流腹部动态增强扫描方案的临床应用的可行性。材料与方法本前瞻性研究获机构审查委员会批准,并获得了病人的知情同意书。此研究共纳入151例病人,其中估算肾小球滤过率(eGFR)大于或等于60mL·min-1·1.73m-2的117例

关键词：扫描方案低剂量对比剂低管电压管电流肾功能衰竭肾衰肾疾病螺旋动态增强扫描病人腹部躯干临床应用 CT

QuantiFERON~-TB Gold试验在结核病接触者筛查和活动性结核病预测中的应用

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

国际结核病与肺部疾病杂志 2011年第1期6卷 7-16页

作者： T.Yoshiyama N.harada K.Higuchi Y.Sekiya K.Uchimura 姜晓颖刘宇红 First Clinical Department Fukujuji HospitalTokyo Mycobacterium Reference and Research and Research Institute of TuberculosisYokyoKiyoseJapan Mycobacterium Reference and Research and Research Institute of TuberculosisYokyoKiyoseJapan Epidemiology and Clinical Research Research Institute of TuberculosisYokyoKiyoseJapan

目的:评估QuantiFERON-TBGold(QFT-G)试验在筛查结核病(TB)接触者、以及评估其发展为活动性结核病的风险方面的效果。方法:收集公共卫生中心结核病密切接触者接受QFT-G试验2年后,临床进展为活动性结核病的资料。结果:3102例观察的接... 详细信息

目的:评估QuantiFERON-TBGold(QFT-G)试验在筛查结核病(TB)接触者、以及评估其发展为活动性结核病的风险方面的效果。方法:收集公共卫生中心结核病密切接触者接受QFT-G试验2年后,临床进展为活动性结核病的资料。结果:3102例观察的接触者中,有419例QFT-G阳性,其中323例开始异烟肼(INH)治疗。419例中的20例(4.8%)发展为结核病。在平均随访的1.6年时间里,2683例QFT-G-阴性人群中,19例被诊断为结核病(0.7%)。QFT-G对于检测可能发展为活动性结核病的接触者的敏感性估计为51%,对于进行异烟肼治疗估计的敏感性为64%。在QFT-G阴性接触者中,所有发展为结核病的都是高度传染病例的接触者。没有进行大规模的结核分枝杆菌素皮肤试验。结论:QFT-G阳性接触者中结核病发病率比QFT-G阴性接触者要高,但是QFT-G阴性接触者中的结核病病例数也是不可忽视的,尤其是具有高传染性结核病例的接触者。

关键词：结核病 QuantiFERON-TBGold 进展为结核病预测

Hepcidin/ferroportin expression levels involve efficacy of pegylated-interferon plus ribavirin in hepatitis C virusinfected liver

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2015年第11期21卷 3291-3299页

作者： Motoyuki Kohjima Tsuyoshi Yoshimoto Munechika Enjoji Nobuyoshi Fukushima Kunitaka Fukuizumi Tsukasa Nakamura Miho Kurokawa Nao Fujimori Yusuke Sasaki Yasushi Shimonaka Yusuke Murata Susumu Koyama Ken Kawabe Kazuhiro Haraguchi Yorinobu Sumida Naohiko harada Masaki Kato Kazuhiro Kotoh Makoto Nakamuta Department of Gastroenterology and Clinical Research Center National Hospital Organization Kyushu Medical Center Health Care Center Fukuoka University Product Research Department Chugai Pharmaceutical Co.Ltd. Department of Medicine and Bioregulatory Science Kyushu University

AIM:To investigate the relationship between the ironmetabolism-related gene expression profiles and efficacy of antiviral therapy in chronic hepatitis C ***:The hepatic expression profile of ironmetabolism-related genes was analyzed and its association with virological response to pegylated-interferon plus ribavirin combination therapy was evaluated.A hundred patients with chronic hepatitis C(genotype1b,n = 50; genotype 2,n = 50) were enrolled and retrospectively *** biopsy samples were subjected to quantitative polymerase chain reaction for iron-metabolismrelated genes and protein expression(Western blotting analysis) for *** a control,normal liver tissue was obtained from 18 living donors of liver *** hepcidin level was measured by sensitive liquid chromatography/electrospray ionization tandem mass ***:Iron overload is associated with liver damage by increasing oxidative stress and hepatitis C virus(HCV)is reported to induce iron accumulation in hepatocytes in ***,iron administration suppresses HCV replication in ***,the association between HCV infection and iron metabolism remains *** with controls,patients had significantly higher gene expression for transferrin,iron-regulatoryproteins 1 and 2,divalent metal transporter 1,and ferroportin,but similar for transferrin receptors 1 and2,and *** the expression profiles were compared between sustained virological response(SVR)and non-SVR patients,the former showed significantly lower transcription and protein expression of hepcidin and *** of hepcidin-regulating genes,BMPR1,BMPR2,and hemojuvelin,was significantly increased,whereas BMP2 was decreased in HCV-infected ***2 and hemojuvelin expression was significantly lower in the SVR than non-SVR *** infection affects the expression of iron-metabolism-related genes,leading to iron accumulation in ***:Decrea

关键词： Chronic hepatitis C Iron-metabolism Hepcidin Ferro

Typical gastroduodenal endoscopic findings in a Crohn's disease patient in remission stage

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Endoscopy 2012年第3期4卷 96-98页

作者： Masahiro Iizuka Taku harada Hiro-o Yamano Takeshi Etou Shiho Sagara Department of Gastroenterology Akita Red Cross HospitalAkita 010-1495Japan Akita Health Care Center Akita Red Cross Hospital

A 39-year-old patient with Crohn's disease (CD) was referred to our hospital for maintenance treatment of *** was diagnosed as having CD of the small and large intestines at 32 years *** underwent partial resection of the ileum at 35 years old because of ileal *** had received enteral nutritional supplement (1200 kcal/d) and metronidazole preparation (500 mg/d),and was in remission Crohn's disease activity index *** performed a routine gastroduodenal endoscopic examination,which revealed the representative endoscopic findings of gastroduodenal lesions in CD,namely,bamboo-joint-like appearance of the gastric body and cardia and a notched sign in the *** findings were clearly observed by using indigo carmine dye *** our patient,typical gastroduodenal findings were observed even in the remission stage,suggesting that these findings would contribute to the early diagnosis of CD not only in the active stage but also during remission.

关键词： Crohn’s disease Gastroduodenal findings Bamboo-joint-like appearance Notched sign