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Characterization of focal liver lesions with SonoVue~-enhanced sonography: International multicenter-study in comparison to CT and MRI

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World Journal of Gastroenterology 2009年第30期15卷 3748-3756页

作者： hervé trillaud Jean-Michel Bruel Pierre-Jean Valette Valérie Vilgrain Gérard Schmutz Raymond Oyen Wieslaw Jakubowski Jan Danes Vlastimil Valek Christian Greis Department of radiology University of Victor Segalen Bordeaux 2CHU Bordeaux Hospital Saint André1 rue Jean Burguet33075 BordeauxFrance Department of radiology CHU of Montpellier HospitalSaint Eloi34295 MontpellierCedex 5France Department of radiology CHU Lyon University69437 Lyon Cedex 03France Department of radiology Hospital Beaujon92110 ClichyFrance Department of radiology Hospital CaenCaen14033 Caen CedexFrance Department of radiology University Hospitals LeuvenGasthuisbergHerestrat 493000 LeuvenBelgium Department of radiology Zaklad Diagnostyki ObrazowejWojewodzki Zespol Publicznych ZakladowOpieki Zdrowotnejul Kendrtatowicza 803-242 WarszawaPoland Department of Radiology General University HospitalU Nemocnice 212000 Praha 2Czech Republic Department of Radiology University Hospital Brno BohuniceJihlavka 2063900 BrnoCzech Republic Ultrasound Medical Department Bracco Imaging Deutschland GmbHMax-Stromeyer-Strasse 11678467 KonstanzGermany

AIM： To evaluate in a multicenter study whether the sonographic characterization of focal liver lesions can be improved using SonoVue-enhancement; and to compare this method with computed tomography （CT） and magnetic resonance imaging （MRI）. METHODS： One hundred and thirty four patients withone focal liver lesion detected in baseline ultrasound （US） were examined with conventional US, contrastenhanced US （n = 134）, contrast-enhanced CT （n = 115） and/or dynamic contrast-enhanced MRI （n = 70）. The lesions were classified as malignant, benign or indeterminate and the type of lesion was determined. The final diagnosis based on the combined information of all imaging examinations, clinical information and histology （n = 32） was used. Comparisons were made to see whether the addition of contrast-enhanced US led to the improvement of the characterization of doubtful focal liver lesions.RESULTS： In comparison with unenhanced US, SonoVue markedly improves sensitivity and specificity for the characterization （malignant/benign） of focal liver lesions. In comparison with CT and/or dynamic MRI, SonoVue -enhanced sonography applied for characterization of focal liver lesions was 30.2% more sensitive in the recognition of malignancy and 16.1% more specific in the exclusion of malignancy and overall 22.9% more accurate. In the subgroup with confirmative histology available （n = 30）, sensitivity was 95.5% （CEUS）, 72.2% （CT） and 81.8% （MRI）, and specificity was 75.0% （CEUS）, 37.5% （CT） and 42.9% （MRI）. The sensitivity and specificity of CEUS for the identification of focal nodular hyperplasia （FNH） and hemangiomas was 100% and 87%, resulting in an accuracy of 94.5%.CONCLUSION： SonoVue-enhanced sonography emerges as the most sensitive, ost specific and thus most accurate imaging modality for the characterization of focal liver lesions.

关键词： Contrast-enhanced sonography Contrastmedia Dynamic sonography Liver lesion Liverdisease Liver Oncologic imaging Sonography

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OLD AND RECENT RESULTS IN THE ANALYTIC THEORY OF DIRICHLET SERIES:A SURVEY

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Acta Mathematica Scientia 2021年第6期41卷 2107-2122页

作者： hervé QUEFFéLEC Université des Sciienes et Technologies de Lille Laboratoire Paul Painlevé U.M.R.CNRS 8524 U.F.R.de Mathématiques59655VILLENEUVE D’ASCQ CedexFrance

This survey is dedicated to the memory of Professor Jiarong Yu,who recently passed *** is concerned by a topic of which he was fond,an interest shared by myself:the analytic theory of Dirichlet series.

关键词： Dirichlet series analytic theory

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2-Dimensional FEM modeling of macrosegregation in the directional solidification with mesh adaptation

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Acta Metallurgica Sinica(English Letters) 2009年第3期22卷 233-240页

作者： Weitao LIU Changchuan XIE Michel Bellet hervé Combeau Beijing Metallurgical Technology Research Institute CCTEC Engineering Corporation Limited Beijing 100081 China School of Metallurgical and Ecological Engineering University of Science and Technology Beijing Beijing 100083 China Ecole des Mines de Paris Sophia Antipolis 06904 France and Ecole des Mines de Nancy Nancy 54042France

In order to improve the prediction accuracy of macrosegregation channel, an algorithm for dynamic remeshing is proposed. The basic idea is to generate fine elements near the liquidus isotherm. The norm of the gradient of solid fraction is used for piloting the remeshing in the mushy zone; whereas, the objective mesh size in the liquid is considered as a function of the distance to the liquidus isotherm. The efficiency of mesh adaptation is demonstrated by prediction of macrosegregation channel in a case of unidirectional solidification.

关键词： Freckle Solidification Modeling Adaptive remeshing

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Solids behavior in dilute zone of a CFB riser under turbulent conditions

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Particuology 2011年第6期9卷 598-605页

作者： Abdelghafour Zaabout hervé Bournot René Occelli Abdeslam Draoui IUSTI Technople de Chateau Gombert 5 rue Enrico FERMI Laboratoire d'Energétique Université Abdelmalek Essaadi

The behavior of the solid phase in the upper zone of a circulating fluidized bed riser was studied using a phase Doppler anemometer. Glass particles of mean diameter 107μm and superficial gas velocities UE covering the turbulent and the beginning of the fast fluidization regime were investigated. Three static bed heights were tested. Ascending and descending particles were found co-existing under all oper ating conditions tested, and at all measurement locations. Superficial gas velocity proved/happened to have a larger effect on descending particles at the wall and on ascending particles in the central region. Transversal particle velocities in both directions （toward the center and toward the wall） behaved rela- tively equivalently, with only slight difference observed at the wall. However, observation of the number of particles moving in either transversal direction showed a change in bed structure when increasing Ug. Furthermore, a balance was constantly observed between the core zone and the annulus zone where the mutual mass transfer between these two zones occurred continuously. Transition from a slow to a fast particle motion was accompanied by a transition to high levels of velocity fluctuations, and was found corresponding to the appearance of significant solid particle flow rate.

关键词： Bed structure Turbulent fluidization regime Solid phase behavior Phase Doppler anemometer Particle velocity Transition velocity

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Displacement manifold method for type synthesis of lower-mobility parallel mechanisms

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Science China(Technological Sciences) 2004年第6期47卷 641-650页

作者： LI Qinchuan HUANG Zhen Jacques Marie hervé Center of Integration Engineering Zhejiang University of SciencesHangzhou 310033China Robotics Research Center Yanshan UniversityQinhuangdao 066004China Ecole Centrale Paris France

Type synthesis of lower-mobility parallel mechanisms is a hot and frontier topic in international academic and industrial field. Based on the Lie group theory, a displacement manifold synthesis method is proposed. For all the nine kinds of lower-mobility parallel mechanisms, the mechanism displacement manifold, limb displacement manifold and the geometrical conditions which guarantee that the intersection of the limb displacement manifold is the desired mechanism displacement manifold are enumerated. Various limb kinematic chains can be obtained using the product closure of displacement subgroup. Parallel mechanisms can be constructed with these limbs while obeying the geometrical conditions. Hence, all the nine kinds of lower-mobility parallel mechanisms can be synthesized using this method. Since displacement manifold deals with finite motion, the result mechanism of synthesis have full-cycle mobility. Novel architectures of lower-mobility parallel mechanisms can be obtained using this method.

关键词： lower-mobility parallel mechanisms Lie group displacement manifold type synthesis

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Artificial intelligence and liver transplantation:Looking for the best donor-recipient pairing

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Hepatobiliary & Pancreatic Diseases International 2022年第4期21卷 347-353页

作者： Javier Briceno Rafael Calleja César hervás Unit of Liver Transplantation Department of General SurgeryHospital Universitario Reina SofíaCórdobaSpain Maimónides Institute of Biomedical Research of Córdoba(IMIBIC) CórdobaSpain Department of Computer Sciences and Numerical Analysis Universidad de CórdobaCórdobaSpain

Decision-making based on artificial intelligence(AI)methodology is increasingly present in all areas of modern *** recent years,models based on deep-learning have begun to be used in organ *** into account the huge number of factors and variables involved in donor-recipient(DR)matching,AI models may be well suited to improve organ ***-based models should provide two solutions:complement decision-making with current metrics based on logistic regression and improve their *** of classifiers could be used to address this ***,not all of them are really useful for D-R ***,in the decision to assign a given donor to a candidate in waiting list,a multitude of variables are handled,including donor,recipient,logistic and perioperative *** these last two,some of them can be inferred indirectly from the team’s previous *** groups of AI models have been used in the D-R matching:artificial neural networks(ANN)and random forest(RF).The former mimics the functional architecture of neurons,with input layers and output *** algorithms can be uni-or *** general,ANNs can be used with large databases,where their generalizability is ***,they are models that are very sensitive to the quality of the databases and,in essence,they are black-box models in which all variables are ***,these models do not allow to know safely the weight of each *** the other hand,RF builds decision trees and works well with small *** addition,they can select top variables as with logistic ***,they are not useful with large databases,due to the extreme number of decision trees that they would generate,making them *** ANN and RF allow a successful donor allocation in over 80%of D-R pairing,a number much higher than that obtained with the best statistical metrics such as model for end-stage liver disease,balance of risk

关键词： Donor-recipient matching Artificial intelligence Deep learning Artificial neural networks Random forest Liver transplantation outcome

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Combining Thermochronology and Geochronology to Constrains Orogenic Processes in the Alps and Tibet

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Acta Geologica Sinica(English Edition) 2024年第S1期98卷 41-43页

作者： Philippe hervéLELOUP Antoine MERCIER GE Chenglong Laboratoire de Géologie de Lyon:Terre Planètes et EnvironnementCNRSUniversitéClaude Bernard Lyon 1ENSLUJM2 rue Raphaël Dubois69622 VilleurbanneFrance Key Laboratory of Deep-Earth Dynamics of Ministry of Natural Resources Institute of GeologyChinese Academy of Geological SciencesBeijing 100037China

Deciphering the kinematics of deformation is key to understand the crustal *** the last decades several techniques have been developed to help constraining the timing of *** one side geochronology techniques allow the dating of a wider range of minerals with higher spatial *** the other side thermochronology,with the help of numerical simulations(PeCube,QTQt…),help to constrain the rock exhumation history that is often linked to the vertical component of *** both cases the deformation timing can accurately be discussed only together with a serious structural analysis.

关键词： timing of crustal deformation eochronology thermochronology Alpine external crystalline range Mont-Blanc Aiguilles Rouges

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Side channel attacks for architecture extraction of neural networks

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CAAI Transactions on Intelligence Technology 2021年第1期6卷 3-16页

作者： hervéChabanne Jean-Luc Danger Linda Guiga Ulrich Kühne Idemia ParisFrance Télécom Paris Institut Polytechnique de ParisParisFrance

Side channel attacks(SCAs)on neural networks(NNs)are particularly efficient for retrieving secret information from *** differentiate multiple types of threat scenarios regarding what kind of information is available before the attack and its purpose:recovering hyperparameters(the architecture)of the targeted NN,its weights(parameters),or its *** this survey article,we consider the most relevant attacks to extract the architecture of *** also categorize SCAs,depending on access with respect to the victim:physical,local,or *** targeting the architecture via local SCAs are most *** of today,physical access seems necessary to retrieve the weights of an *** notably describe cache attacks,which are local SCAs aiming to extract the NN's underlying *** countermeasures have emerged;these are presented at the end of the survey.

关键词： architecture networks neural

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Enhancement of the group delay in quadratic coupling optomechanical systems subjected to an external force

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Chinese Physics B 2023年第12期32卷 325-331页

作者： Jimmi hervéTalla Mbé Ulrich Chancelin Tiofack Demanou Christian Kenfack-Sadem Martin Tchoffo Research Unit of Condensed Matter Electronics and Signal ProcessingDepartment of PhysicsUniversity of DschangP.O.Box 67DschangCameroon African Institute for Mathematical Sciences P.O.Box 608LimbeCameroon

We theoretically study the effect of the quadratic coupling strength on optomechanical systems subjected to a continuous external force. Quadratic coupling strength originates from strong coupling between the optical and the mechanical degrees of freedom. We show that the quadratic coupling strength reduces the amplitude of the dispersion spectra at the resonance in both blue-and red-sideband regimes. However, it increases(decreases) the amplitude of the absorption spectrum in the blue-(red-)sideband regime. Furthermore, in both sideband regimes, the effective detuning between the pump and the cavity deviates with the quadratic coupling strength. Thereby, appropriate selection of the quadratic coupling strength results in an important magnification(in absolute value) of the group delay for both slow and fast light exiting from the optomechanical cavity.

关键词： slow and fast light optomechanical systems group delay quadratic coupling

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Parity violation in chiral structure creation under femtosecond laser irradiation in silica glass?

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Light(Science & Applications) 2016年第1期5卷 371-377页

作者： Bertrand Poumellec Matthieu Lancry Rudy Desmarchelier Evelyne hervé Bernard Bourguignon SP2M/ICMMO CNRS-UPSudUniversitéParis SudUniversitéParis SaclayBâtiment 410Orsay 91405 CedexFrance Centre des matériaux Mines ParisParistechUMR CNRS-UPMC 7633BP87Evry F-91003 CedexFrance ISMO CNRS-UPSudUniversitéParis SudUniversitéParis SaclayBâtiment 210Orsay 91405 CedexFrance

The paper addresses the creation of circular optical properties from a femtosecond laser light beam with a linear polarization in an achiral material(glass)under an orthogonal *** this situation,all aspects of the experiment are achiral and therefore should not give rise to chiral property *** that observation,we propose an interpretation that involves the action of a light-induced torque on the matter carrying a light-induced dielectric *** found that a direct current(DC)electric field could be produced in the lattice by the femtosecond laser in our conditions and that a non-collinear dielectric moment is created by a nonlinear effect between the DC electric field and the stress field due to the transformation of the *** reveal that it is possible to break the chiral symmetry of glass using an intense,ultrashort laser light pulse.

关键词： chirality chiroptical properties circular dichroism femtosecond laser processing glass optical rotation silica

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