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Interictal and Ictal MEG in presurgical evaluation for epilepsy surgery

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Acta Epileptologica 2020年第1期2卷 83-92页

作者： hermann stefan stefan Rampp Department of Neurology-Biomagnetism University Hospital Erlangen6Schabachanlage91054 ErlangenGermany. Department of Neurosurgery University Hospital Erlangen6SchabachanlageErlangenGermany.

Although presurgical evaluation of patients with pharamacoresistent focal epilepsies provides essential information for successful epilepsy surgery,there is still a need for further *** of noninvasive electrophysiological recording and analysis techniques offer additional information based on interictal and ictal epileptic *** this review,we provide an overview on the application of ictal magnetoencephalography(MEG).The results of a literature research for published interictal/ictal MEG findings and experiences with own cases are demonstrated and *** MEG may provide added value in comparison to interictal *** results may be more focal and closer to the invasively determined seizure onset *** some patients without clear interictal findings,ictal MEG could provide correct *** recording and analysis techniques facilitate ictal ***,extended recording durations,movement and artifacts still represent practical *** MEG may provide added value regarding the localization of the seizure onset zone but depends on the selection of patients and the application of optimal analysis techniques.

关键词： Ictal MEG Interictal MEG Localization of epileptic activity Presurgical evaluation

Ictal semiology,functional anatomy and multimodal diagnostic in patients with insular epilepsies

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Acta Epileptologica 2019年第1期1卷 49-58页

作者： hermann stefan Stephanie Gollwitzer Department of Neurology BiomagnetismUniversity Hospital Erlangen10SchwabachanlageD-91054 ErlangenGermany. Department of Neurology Epilepsy CenterUniversity Hospital ErlangenErlangenGermany.

Background:The insula is a hidden part in the cerebral *** epilepsy is underrecognized and it bears a special risk for misdiagnosis with regard to nonepileptic seizures or wrong localization of epileptic *** presentations:The manuscript describes 2 cases with ictal semiology of paresthesia and pain followed by hyperkinetic movements,noninvasive findings of source localization and/or invasive SEEG ***:Magnetic source imaging,ictal SPECT as noninvasive and invasive recordings with depth electrodes(SEEG)can provide important preoperative information for the involvement of insular and periinsular regions in focal pharmacoresistant *** optimal use of these methods presupposes extensive knowledge of ictal semiology and other clinical *** clinical localization hypothesis can be optimally proofed by SEEG exploration.

关键词： Insular epilepsy Ictal semiology Source localization MEG/EEG SEEG

Correction to:Ictal semiology,functional anatomy and multimodal diagnostic in patients with insular epilepsies

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Acta Epileptologica 2019年第1期1卷 59-61页

作者： hermann stefan Stephanie Gollwitzer Department of Neurology BiomagnetismUniversity Hospital Erlangen10SchwabachanlageD91054 ErlangenGermany Department of Neurology Epilepsy CenterUniversity Hospital ErlangenErlangenGermany

After publication of this article [1], it is noticed there are errors with figure numbering and matching between figure artwork and caption with Figs. 3, 4, 5 and 6. The correct Figs. 3, 4, 5 and 6 are as follows. We ...

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可靠监测水处理工艺流程

流程工业 2015年第12期 34-34,37页

作者： Joe hermann stefan Diepenbrock Baumer电气技术公司

传感器保证了供水过程的可靠监控——在水资源的输送和分配过程中，必须用传感器对地下水开采过程进行监控和调节，以防止潜水泵空转。为了保证工艺流程的一切正常，Baumer公司不断推出最合适的监控解决方案。

关键词：工艺流程水处理监测供水过程开采过程传感器水资源监控

不可或缺的监控传感器保证了供水过程的可靠性

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流程工业 2014年第2期 24-25页

作者： Joe hermann stefan Diepenbrock 瑞士Frauenfeld市Baumer电气公司

在水资源的开采、准备处理和分配中要利用传感器对地下水的开采过程进行监控和调节。为了保证潜水泵不出现失油干运行、海水淡化设备无故障的正常运行，Baumer公司提供了最合适的监控工具。

关键词：监控工具传感器供水过程可靠性海水淡化设备开采过程正常运行水资源

Preparing for a “dirty bomb” attack: The optimum mix of medical countermeasure resources

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Military Medical Research 2021年第3期8卷 336-351页

作者： Alexis Rump Patrick Ostheim stefan Eder Cornelius hermann Michael Abend Matthias Port Bundeswehr Institute of Radiobiology Neuherberg Str.n80937 MunichGermany

Background: In radiological emergencies with radionuclide incorporation, decorporation treatment is particularly effective if started early. Treating all people potentially contaminated("urgent treatment") may require large antidote stockpiles. An efficacious way to reduce antidote requirements is by using radioactivity screening equipment. We analyzed the suitability of such equipment for triage purposes and determined the most efficient mix of screening units and antidote daily ***: The committed effective doses corresponding to activities within the detection limits of monitoring portals and mobile whole-body counters were used to assess their usefulness as triage tools. To determine the optimal resource mix, we departed from a large-scale scenario(60,000 victims) and based on purchase prices of antidotes and screening equipment in Germany, we calculated efficiencies of different combinations of medical countermeasure resources by data envelopment analysis. Cost-effectiveness was expressed as the costs per life year saved and compared to risk reduction opportunities in other sectors of society as well as the values of a statistical ***: Monitoring portals are adequate instruments for a sensitive triage after cesium-137 exposure with a high screening throughput. For the detection of americium-241 whole-body counters with a lower daily screening capacity per unit are needed. Assuming that 1% of the potentially contaminated patients actually need decorporation treatment, an efficient resource mix includes 6 monitoring portals and 25 mobile whole-body counters. The optimum mix depends on price discounts and in particular the fraction of victims actually needing treatment. The costeffectiveness of preparedness for a "dirty bomb" attack is less than for common health care, but costs for a life year saved are less than for many risk-reduction interventions in the environmental ***: To achieve economic efficiency a high daily screening ca

关键词： Radiological emergency Dirty bomb Medical countermeasures Radionuclide incorporation Decorporation treatment Screening Efficiency Data envelopment analysis

CO_(2)capture costs of chemical looping combustion of biomass:A comparison of natural and synthetic oxygen carrier

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Journal of Energy Chemistry 2024年第5期92卷 296-310页

作者： Benjamin Fleiß Juraj Priscak Martin Hammerschmid Josef Fuchs stefan Müller hermann Hofbauer Institute of Chemical Environmental and Bioscience EngineeringTU WienVienna1060 ViennaAustria BEST–Bioenergy and Sustainable Technologies GmbH Graz8010 StyriaAustria

Chemical looping combustion has the potential to be an efficient and low-cost technology capable of contributing to the reduction of the atmospheric concentration of CO_(2) in order to reach the 1.5/2°C goal and mitigate climate *** this process,a metal oxide is used as oxygen carrier in a dual fluidized bed to generate clean CO_(2) via combustion of *** commonly,natural ores or synthetic materials are used as oxygen carrier whereas both must meet special requirements for the conversion of solid *** oxygen carriers are characterized by higher reactivity at the expense of higher costs versus the lower-cost natural *** determine the viability of both possibilities,a techno-economic comparison of a synthetic material based on manganese,iron,and copper to the natural ore ilmenite was *** synthetic oxygen carrier was characterized and tested in a pilot plant,where high combustion efficiencies up to 98.4%and carbon capture rates up to 98.5%were *** techno-economic assessment resulted in CO_(2) capture costs of 75 and 40€/tCO_(2) for the synthetic and natural ore route respectively,whereas a sensitivity analysis showed the high impact of production costs and attrition rates of the synthetic *** synthetic oxygen carrier could break even with the natural ore in case of lower production costs and attrition rates,which could be reached by adapting the production process and recycling *** comparison to state-of-the-art technologies,it is demonstrated that both routes are viable and the capture cost of CO_(2) could be reduced by implementing the chemical looping combustion technology.

关键词： Chemical looping combustion BECCS Techno-economic assessment CO_(2)capture costs Oxygen carrier development Synthetic materials Ilmenite

Estimation of radiation-induced health hazards from a“dirty bomb”attack with radiocesium under different assault and rescue conditions

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Military Medical Research 2022年第1期9卷 106-125页

作者： Alexis Rump stefan Eder Cornelius hermann Andreas Lamkowski Patrick Ostheim Michael Abend Matthias Port Bundeswehr Institute of Radiobiology Neuherberg Str.1180937 MunichGermany

In the case of a terrorist attack by a“dirty bomb”,blast injuries,external irradiation and the incorporation of radioactivity are to be *** from information about the radiological attack scenario with cesium-137 in the *** Scenario Planning Guide,we estimated the radiological doses *** calculations were performed for a smaller plume size and a detonation in a *** conditions as described in the ***,the committed effective dose amounted to a maximum of 848 mSv,even for very unfavorable *** bone marrow equivalent doses are insufcient to induce acute radiation sickness(ARS).In the case of a smaller plume size,the ARS threshold may be exceeded in some *** a subway bombing,doses are much higher and the occurrence of ARS should be *** health hazards from a dirty bomb attack will depend on the location and the explosive *** derived Haddon matrix indicates that preparing for such an event includes education of all the medical staff about radiation effects,the time lines of radiation damages and the treatment *** determinants of the outcome include rapid evacuation even from difficult locations,the availability of a specific triage tool to rapidly identify victims at risk for ARS,the availability of an antidote stockpile and dedicated hospital beds to treat seriously irradiated victims.

关键词： Medical NRBC protection Terrorism Radiological emergency Dirty bomb Combined injuries Triage Acute radiation sickness Radionuclide incorporation

Analysis of metabolic alterations in Arabidopsis following changes in the carbon dioxide and oxygen partial pressures

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Journal of Integrative Plant Biology 2014年第9期56卷 941-959页

作者： Alexandra Florian stefan Timm Zoran Nikoloski Takayuki Tohge hermann Bauwe Wagner L.Araujo Alisdair R.Fernie Max Planck Institute for Molecular Plant Physiology Department of Plant Physiology University of Rostock Max-Planck Partner group at the Departament of Plant Biology Federal University of Vicosa

As sessile organisms,plants are subject to a multitude of environmental variations including several which directly affect their interaction with the *** the indiscriminant nature of Rubisco,the relative rates of photosynthesis and photorespiration are known to be responsive to changes in gas ***,comprehensive profiling methods have not yet been applied in order to characterize the wider consequences of these changes on primary metabolism in ***,although transcriptional profiling has revealed that a subset of photorespiratory enzymes are co-expressed,whether transcriptional responses play a role in short-term responses to atmospheric compositional changes remains *** address these questions,plants Arabidopsis thaliana（Arabidopsis） ecotype Columbia（Col-O） grown under normal air conditions were transferred to different CO_2 and O_2 concentrations and characterized at the physiological,molecular,and metabolic levels following this *** results reveal alterations in the components,which are directly involved in,or supporting,photorespiration,including transcripts and metabolite *** results further highlight that the majority of the regulation of these pathways is not mediated at the level of transcription and that the photorespiratory pathway is essential also in conditions in which flux through the pathway is minimized,yet suggest that flux through this pathway is not mediated at the level of transcription.

关键词： Carbon dioxide partial pressures gene expression metabolic profiling oxygen partial pressures