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Do patients with gastroesophageal reflux disease and somatoform tendencies benefit from antireflux surgery?

World Journal of Gastroenterology 2019年第3期25卷 388-397页

作者： Hans Friedrich Fuchs Benjamin Babic Karl-hermann Fuchs Wolfram Breithaupt Gabor Varga Frauke Musial Department of General Surgery University of Cologne Department of General Surgery University of Mainz Department of Surgery University of California San Diego Department of Surgery Goethe University Frankfurt National Research Center in Complementary and Alternative Medicine NAFKAM Department of Community Medicine UiT The Arctic University of Norway

BACKGROUND The clinical presentation of gastroesophageal reflux disease(GERD) shows a large symptom variation also in different intensities among patients. As several studies have shown, there is a large overlap in the symptomatic spectrum between proven GERD and other disorders such as dyspepsia, functional heartburn and/or somatoform *** To prospectively evaluate the GERD patients with and without somatoform disorders before and after laparoscopic antireflux *** In a tertiary referral center for foregut surgery over a period of 3 years patients with GERD, qualifying for the indication of laparoscopic antireflux surgery, were investigated prospectively regarding their symptomatic spectrum in order to identify GERD and associated somatoform disorders. Assessment of symptoms was performed by an instrument for the evaluation of somatoform disorders[Somatoform Symptom Index(SSI) > 17]. Quality of life was evaluated by Gastrointestinal Quality of Life Index(GIQLI).RESULTS In 123 patients an indication for laparoscopic antireflux surgery was established and in 43 patients further medical therapy was suggested. The portion of somatoform tendencies in the total patient population was 20.48%(34 patients).Patients with a positive SSI had a preoperative GIQLI of 77(32-111). Patients with a normal SSI had a GIQLI of 105(29-140)(P < 0.0001). In patients with GERD the quality of life could be normalized from preoperative reduced values of GIQLI102(47-140) to postoperative values of 117(44-144). In patients with GERD and somatoform disorders, the GIQLI was improved from preoperative GIQLI 75(47-111) to postoperative 95(44-122)(P < 0.0043).CONCLUSION Patients with GERD and associated somatoform disorders have significantly worse levels of quality of life. The latter patients can also benefit from laparoscopic fundoplication, however they will not reach a normal level.

关键词： Gastroesophageal reflux disease Antireflux surgery Laparoscopic fundoplication Somatization Gastroesophageal reflux disease symptoms

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Mrchen vom Korbstuhl

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德语学习 2008年第2期 10-15页

作者： hermann Hesse

hermann Hesse wurde a m *** 1877 in Calw/Wrttemberg als Sohn eines baltendeutschen Missionars und einer wrttembergischen Missionarstochter

关键词：德语学习方法阅读训练教学方法

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Altered PIWI-LIKE 1 and PIWI-LIKE 2 mRNA expression in ejaculated spermatozoa of men with impaired sperm characteristics

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Asian Journal of Andrology 2018年第3期20卷 260-264页

作者： Maria Giebler Thomas Greither Lisa Muller Carina Mosinger hermann M Behre Center for Reproductive Medicine and Andrology Martin Luther University Halle-Wittenberg Halle (Saale) 06120 Germany.

In about half the cases of involuntary childlessness, a male infertility factor is involved. The PIWI-LIKE genes, a subclade of the Argonaute protein family, are involved in RNA silencing and transposon control in the germline. Knockout of murine Piwi-like 1 and 2 homologs results in complete infertility in males. The aim of this study was to analyze whether the mRNA expression of human PIWI-LIKE I-4 genes is altered in ejaculated spermatozoa of men with impaired sperm characteristics. Ninety male participants were included in the study, among which 47 were with normozoospermia, 36 with impaired semen characteristics according to the World Health Organization （WHO） manual, 5th edition, and 7 with azoospermia serving as negative control for the PIWI-LIKE 1-4 mRNA expression in somatic cells in the ejaculate. PIWI-LIKE 1-4 mRNA expression in the ejaculated spermatozoa of the participants was measured by quantitative real-time PCR. In nonazoospermic men, PIWIoLIKE 1-4 mRNA was measurable in ejaculated spermatozoa in different proportions. PIWI-LIKE 1 （100.0%） and PIWI-LIKE 2 （49.4%） were more frequently expressed than PIWI-LIKE3 （9.6%） and PIWI-LIKE 4 （15.7%）. Furthermore, a decreased PIWI-LIKE2 mRNA expression showed a significant correlation with a decreased sperm count （P = 0.022） and an increased PIWI-LIKE 1 mRNA expression with a decreased progressive motility （P = 0.048）. PIWI-LIKE 1 and PIWI-LIKE 2 mRNA expression exhibited a significant association with impaired sperm characteristics and may be a useful candidate for the evaluation of the impact of PIWI-LIKE 1-4 mRNA expression on male infertility.

关键词： male infertility Piwi PIWI-LIKEgenes sperm quality parameters

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Galactic Route to the Strong Coupling Constant α_s(m_z) and Its Implication on the Mass Constituents of the Universe

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Journal of Applied Mathematics and Physics 2022年第12期10卷 3572-3585页

作者： Hans hermann Otto Materials Science and Crystallography Clausthal University of Technology Clausthal-Zellerfeld Germany

Some fundamental physical quantities need an alternative description. We derive the word average value of interaction coupling constant αs(mz) from the observed maximum galactic rotation velocity by the simple relation , where is the velocity, at which the difference between galactic rotation velocity and Thomas precession is equal, and α is Sommerfeld’s constant. The result is in excellent agreement with the value of αs = 0.1170 ± 0.0019, recently measured and verified via QCE analysis by CERN researchers. One can formulate a reciprocity relation, connecting αs with the circle constant: . It is the merit of Preston Guynn to derive the Milky Way maximum value of the galactic rotation velocity βg, pointing to its “extremely important role in all physics”. The mass (energy) constituents of the Universe follow a golden mean hierarchy and can simply be related to the maximum of Guynn’s difference velocity respectively to αs(mz), therewith excellently confirming Bouchet’s WMAP data analysis. We conclude once more that the golden mean concept is the leading one of nature.

关键词： Strong Coupling Constant Sommerfeld’ Constant Gravitational Coupling Constant Galactic Velocity Structure-Matter Theory Reciprocity Relation Goldem Mean Hierarchy Mass and Energy Constituents of the Universe Superconductivity Matter-Antimatter Asymmetry Unification of Science

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Golden Quartic Polynomial and Moebius-Ball Electron

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Journal of Applied Mathematics and Physics 2022年第5期10卷 1785-1812页

作者： Hans hermann Otto Materials Science and Crystallography Clausthal University of Technology Clausthal-Zellerfeld Germany

A symmetrical quartic polynomial, named golden one, can be connected to coefficients of the icosahedron equation as well as to the gyromagnetic correction of the electron and to number 137. This number is not a mystic one, but is connected with the inverse of Sommerfeld’s fine-structure constant and this way again connected with the electron. From number-theoretical realities, including the reciprocity relation of the golden ratio as effective pre-calculator of nature’s creativeness, a proposed closeness to the icosahedron may point towards the structure of the electron, thought off as a single-strand compacted helically self-confined charged elemantary particle of less spherical but assumed blunted icosahedral shape generated from a high energy double-helix photon. We constructed a chiral Moebius “ball” from a 13 times 180˚twisted double helix strand, where the turning points of 12 generated slings were arranged towards the vertices of a regular icosahedron, belonging to the non-centrosymmetric rotation group I532. Mathematically put, we convert the helical motion of an energy quantum into a stationary motion on a Moebius stripe structure. The radius of the ball is about the Compton radius. This chiral closed circuit Moebius ball motion profile can be tentatively thought off as the dominant quantum vortex structure of the electron, and the model may be named CEWMB (Charged Electromagnetic Wave Moebius Ball). Also the gyromagnetic factor of the electron (ge = 2.002319) can be traced back to this special structure. However, nature’s energy infinity principle would suggest a superposition with additional less dominant (secondary) structures, governed also by the golden mean. A suggestion about the possible structure of delocalized hole carriers in the superconducting state is given.

关键词： Golden Qartic Polynomial Number Theory Icosahedron Equation Golden Mean Fifth Power of the Golden Mean Moebius Ball Electron Structure Chirality Fine-Structure Constant Fibonacci Number 13 Lucas Numbers Superconductivity

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BUME

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德语人文研究 1999年第2期 4-9页

作者： hermann Hese

ＢｉｎｄｆüｒｍｉｃｈｉｍｍｅｒｄｉｅｅｉｎｄｒｉｎｇｌｉｃｈｓｔｅｎＰｒｅｄｉｇｅｒｇｅｗｅｓｅｎ．Ｉｃｈｖｅｒｅｈｒｅｓｉｅ，ｗｅｎｎｓｉｅｉｎＶｌｋｅｒｎｕｎｄＦａｍｉｌｉｅｎｌｅｂｅｎ，ｉｎＷｌｄｅｒｎｕｎｄ... 详细信息

ＢｉｎｄｆüｒｍｉｃｈｉｍｍｅｒｄｉｅｅｉｎｄｒｉｎｇｌｉｃｈｓｔｅｎＰｒｅｄｉｇｅｒｇｅｗｅｓｅｎ．Ｉｃｈｖｅｒｅｈｒｅｓｉｅ，ｗｅｎｎｓｉｅｉｎＶｌｋｅｒｎｕｎｄＦａｍｉｌｉｅｎｌｅｂｅｎ，ｉｎＷｌｄｅｒｎｕｎｄＨａｉｎｅｎ．Ｕｎｄｎｏｃｈｍｅｈ...

关键词：高飞远走讲道者贝多芬小树丛隐居者合理分配长篇大论原始规母亲家乡

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Nuclear Fusion Research and Development Need New Relativistic Mass and Energy Corrections Given by the Information Relativity Theory

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Journal of Applied Mathematics and Physics 2022年第5期10卷 1813-1836页

作者： Hans hermann Otto Materials Science and Crystallography Clausthal University of Technology Clausthal-Zellerfeld Germany

Hundred years after the conjecture of the British astronomer Eddington that the sun is powered by nuclear fusion of hydrogen, new physics theory may help make energy harvesting by nuclear fusion soon a reality. Researchers as well as investors funding fusion megaprojects are asked to deal with new relativistic corrections for mass and energy proposed by Suleiman in his Information Relativity Theory (IRT). These corrections were calculated in this contribution. It will help to decide whether a venture will be successful and to save big investments when in doubt. The assumed optimal kinetic energy for controlled nuclear fusion must be corrected to a somewhat higher level. At very high kinetic energy in the upper GeV range, it remains not enough baryonic mass to be transformed in energy. The fusion probability faded out to zero already at the golden limit of the recession speed of between target nucleon and projectile nucleon. Cold nuclear fusion, if ever possible, is recommended for protons rather than deuterons at highest experimental possible temperatures around 1000 (K) and needs fine-tuned kinetic nucleon energy. It would be also of interest whether a golden ratio based nuclear fuel confinement chamber could be beneficial. In this connection, also cold nuclear fusion setups should be discussed. Nature is governed by the golden ratio and criticality of physical systems influenced by it, and nuclear physics is not an exception. Computer simulations of the underlying controlled nuclear fusion processes should gain profit from IRT corrected starting information and may tackle anew possible low energy nuclear transmutations considering the wave-like dark components of matter and energy.

关键词： Controlled Thermonuclear Fusion IRT Theory Relativistic Mass Correction Low Energy Nuclear Reaction Golden Ratio Golden Limit of Nuclear Fusion

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Phase Transitions Governed by the Fifth Power of the Golden Mean and Beyond

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World Journal of Condensed Matter Physics 2020年第3期10卷 135-158页

作者： Hans hermann Otto Materials Science and Crystallography Clausthal University of Technology Clausthal-Zellerfeld Lower Saxony Germany

In this contribution results from different disciplines of science were compared to show their intimate interweaving with each other having in common the golden ratio φ respectively its fifth power φ5. The research fields cover model calculations of statistical physics associated with phase transitions, the quantum probability of two particles, new physics of everything suggested by the information relativity theory (IRT) including explanations of cosmological relevance, the ε-infinity theory, superconductivity, and the Tammes problem of the largest diameter of N non-overlapping circles on the surface of a sphere with its connection to viral morphology and crystallography. Finally, Fibonacci anyons proposed for topological quantum computation (TQC) were briefly described in comparison to the recently formulated reverse Fibonacci approach using the

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Fibonacci Stoichiometry and Superb Performance of Nb₁₆W₅O₅₅ and Related Super-Battery Materials

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Journal of Applied Mathematics and Physics 2022年第6期10卷 1936-1950页

作者： Hans hermann Otto Materialwissenschaftliche Kristallographie Clausthal University of Technology Clausthal-Zellerfeld Lower Saxony Germany

In this contribution, two important crystallographic concepts for the formation of a series of block structures associated with channeling have been compared: chemical twinning and crystallographic shear. Twin planes respectively shear planes besides formed channels serve as a sink for charge carriers or, when the oxidation state of metal ions can be reduced, as a reservoir for intercalated lithium. In this way, Wadsley-Roth shear phases such as niobium tungsten oxide exhibit channels for ultra-fast lithium-ion diffusion. They are in focus as anode material for super-batteries, superb in terms of energy respectively power density, charging time, cycle life and safety. It should be noted that the transition metal to oxygen ratio TM/O = 21/55 of the title compound is a Fibonacci number quotient. Also, the crystal lattice can be traced back to Fibonacci geometry. When replacing only 0.0213 tungsten atoms in the formula with less expensive titanium, a TM/O ratio of 0.381966 =ϕ2 can be adapted besides an average valence electron concentration of 2⋅ϕ-2, where represents the most irrational number of the golden mean. The additional disorder caused by even such small titanium replacement and accompanied oxygen vacancies could fasten up the already high lithium diffusion further. Ultrasonic treatment may be applied besides thermal cycling to prepare phase-pure of the highest electrochemical performance. A replacement of oxygen by some fluorine atoms is an obvious synthesis possibility, but the higher binding energy expected between lithium and fluorine in contrast to oxygen may rather hinder than promote lithium diffusion.

关键词： Super Battery Niobium Tungsten Oxide Crystallographic Shear Chemical Twinning Fibonacci Stoichiometry Ti Substitution

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Beyond a Quartic Polynomial Modeling of the DNA Double-Helix Genetic Code

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Journal of Applied Mathematics and Physics 2021年第10期9卷 2558-2577页

作者： Hans hermann Otto Materials Science and Crystallography Clausthal University of Technology Clausthal-Zellerfeld Germany

By combination of finite number theory and quantum information, the complete quantum information in the DNA genetic code has been made likely by Planat et al. (2020). In the present contribution a varied quartic polynomial contrasting the polynomial used by Planat et al. is proposed that considered apart from the golden mean also the fifth power of this dominant number of nature to adapt the code information. The suggested polynomial is denoted as g(x) = x4 - x3 - (4 - ϕ2 )x2 + (4 – ϕ2)x + 1, where is the golden mean. Its roots are changed to more golden mean based ones in comparison to the Planat polynomial. The new coefficients 4 – ϕ2 instead of 4 would implement the fifth power of the golden mean indirectly applying . As an outlook, it should be emphesized that the connection between genetic code and resonance code of the DNA may lead us to a full understanding of how nature stores and processes compacted information and what indeed is consciousness linking everything with each other suggestedly mediated by all-pervasive dark constituents of matter respectively energy. The number-theoretical approach to DNA coding leads to the question about the helical structure of the electron.

关键词： DNA Genetic Code DNA Resonance Code Qartic Polymial Golden Mean Silver Mean Fifth Power of the Golden Mean Fiboacci Number 13 α-Helix Icosahedron Equation Number Theory Quantum Computation Consciousness Dark Energy Electron’s Structure

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