检索结果-南通市图书馆

Curation,nomenclature,and topological classification of receptor-like kinases from 528 plant species for novel domain discovery and functional inference

在线全文

学校读者我要写书评

暂无评论

Molecular Plant 2024年第4期17卷 658-671页

作者： Qian Liu Qiong Fu Yujie Yan Qian Jiang Longfei Mao Long Wang Feng Yu heping zheng State Key Laboratory of Chemo/Biosensing and Chemometrics Hunan University College of BiologyChangshaHunan 410082China Bioinformatics Center Hunan University College of BiologyChangshaHunan 410082China

Receptor-like kinases(RLKs)are the most numerous signal transduction components in plants and play important roles in determining how different plants adapt to their ecological *** on RLKs has focused mainly on a small number of typical RLK members in a few model *** is an urgent need to study the composition,distribution,and evolution of RLKs at the holistic level to increase our understanding of how RLKs assist in the ecological adaptations of different plant *** this study,we collected the genome assemblies of 528 plant species and constructed an RLK *** this dataset,we identified and characterized 524948 RLK family *** member underwent systematic topological classification and was assigned a gene ID based on a unified nomenclature ***,we identified two novel extracellular domains in some RLKs,designated Xiao and *** analysis of the RLK family revealed that the RLCK-XVII and RLCK-XII-2 classes were present exclusively in dicots,suggesting that diversification of RLKs between monocots and dicots may have led to differences in downstream cytoplasmic *** also used an interaction proteome to help empower data mining for inference of new RLK functions from a global perspective,with the ultimate goal of understanding how RLKs shape the adaptation of different plants to the environments/*** assembled RLK dataset,together with annotations and analytical tools,forms an integrated foundation of multiomics data that is publicly accessible via the metaRLK web portal(http://***).

关键词： RLK RLCK domain signaling pathway receptor-protein interactions

FERONIA is involved in phototropin 1-mediated blue light phototropic growth in Arabidopsis

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Plant Biology 2022年第10期64卷 1901-1915页

作者： Chiyu Li Jia Chen Xiaoyan Li Xin Zhang Ying Liu Sirui Zhu Long Wang heping zheng Sheng Luan Jiada Li Feng Yu School of Life Sciences Central South UniversityChangsha 410078China State Key Laboratory of Chemo/Biosensing and Chemometrics College of BiologyHunan UniversityChangsha 410082China Hunan Key Laboratory of Plant Functional Genomics and Developmental Regulation Hunan UniversityChangsha 410082China Department of Plant and Microbial Biology University of CaliforniaBerkeleyCA94720USA State Key Laboratory of Hybrid Rice Hunan Hybrid Rice Research CenterChangsha 410125China

Plant shoot phototropism is triggered by the formation of a light-driven auxin gradient leading to bending *** blue light receptor phototropin 1(phot1)senses light direction,but how this leads to auxin gradient formation and growth regulation remains poorly *** studies have suggested phot1’s role for regulated apoplastic acidification,but its relation to phototropin and hypocotyl phototropism is ***,we show that blue light can cause phot1 to interact with and phosphorylate FERONIA(FER),a known cell growth regulator,and trigger downstream phototropic bending growth in Arabidopsis *** mutants showed defects in phototropic growth,similar to phot1/2 *** also interacts with and phosphorylates phytochrome kinase substrates,the phot1 downstream *** phot1-FER pathway acts upstream of apoplastic acidification and the auxin gradient formation in hypocotyl under lateral blue light,both of which are critical for phototropic bending growth in *** study highlights a pivotal role of FER in the phot1-mediated phototropic cell growth regulation in plants.

关键词： blue light FERONIA H+and auxin gradience formation hypocotyl phototropin 1 phototropism

Structural and biochemical basis of Arabidopsis FERONIA receptor kinase-mediated early signaling initiation

在线全文

学校读者我要写书评

暂无评论

Plant Communications 2023年第4期4卷 132-145页

作者： Yanqiong Kong Jia Chen Lingli Jiang Hong Chen Yanan Shen Lifeng Wang Yujie Yan Huan Zhou heping zheng Feng Yu Zhenhua Ming State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources College of Life Science and TechnologyGuangxi Key Laboratory for Sugarcane BiologyGuangxi UniversityNanning 530004P.R.China State Key Laboratory of Chemo/Biosensing and Chemometrics College of BiologyHunan Key Laboratory of Plant Functional Genomics and Developmental RegulationHunan UniversityChangsha 410082P.R.China State Key Laboratory of Hybrid Rice Hunan Hybrid Rice Research CenterChangsha 410125P.R.China Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghaiP.R.China

Accumulating evidence indicates that early and essential events for receptor-like kinase(RLK)function involve both autophosphorylation and substrate ***,the structural and biochemical basis for these events is largely ***,we used RLK FERONIA(FER)as a model and crystallized its core kinase domain(FER-KD)and two FER-KD mutants(K565R,S525A)in complexes with ATP/ADP and Mg^(2+) in the unphosphorylated *** FER-KD was found to adopt an unexpected active conformation in its crystal ***,unphosphorylated FER-KD mutants with reduced(S525A)or no catalytic activity(K565R)also adopt similar active *** studies revealed that FER-KD is a dual-specificity kinase,and its autophosphorylation is accomplished via an intermolecular *** investigations confirmed that initiating substrate phosphorylation requires autophosphorylation of the activation segment on T696,S701,and *** study reveals the structural and biochemical basis for the activation and regulatory mechanism of FER,providing a paradigm for the early steps in RLK signaling initiation.

关键词： FERONIA active conformation kinase activity autophosphorylation activation

Desmoglein 2(DSG2) Is A Receptor of Human Adenovirus Type 55 Causing Adult Severe Community-Acquired Pneumonia

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Virologica Sinica 2021年第6期36卷 1400-1410页

作者： Jing Zhang Kui Ma Xiangyu Wang Yinbo Jiang Shan Zhao Junxian Ou Wendong Lan Wenyi Guan Xiaowei Wu heping zheng Bin Yang Chengsong Wan Wei Zhao Jianguo Wu Qiwei Zhang Guangdong Provincial Key Laboratory of Virology Institute of Medical MicrobiologyJinan UniversityGuangzhou510632China Guangdong Provincial Key Laboratory of Tropical Disease Research School of Public HealthSouthern Medical UniversityGuangzhou510515China Guangdong Provincial Dermatology Hospital Southern Medical UniversityGuangzhou510091China

Human adenovirus type 55(HAdV-B55) is a re-emergent acute respiratory disease pathogen that causes adult communityacquired pneumonia(CAP). Previous studies have shown that the receptor of HAdV-B14, which genome is highly similar with HAdV-B55, is human Desmoglein 2(DSG2). However, whether the receptor of HAdV-B55 is DSG2 is undetermined because there are three amino acid mutations in the fiber gene between HAdV-B14 and HAdV-B55. Here, firstly we found the 3T3 cells, a mouse embryo fibroblast rodent cell line which does not express human DSG2, were able to be infected by HAdV-B55 after transfected with pcDNA3.1-DSG2, while normal 3T3 cells were still unsusceptible to HAdV-B55 infection. Next, A549 cells with h DSG2 knock-down by siRNA were hard to be infected by HAdV-B3/-B14/-B55, while the control siRNA group was still able to be infected by all these types of HAdVs. Finally, immunofluorescence confocal microscopy indicated visually that Cy3-conjugated HAdV-B55 viruses entered A549 cells by binding to DSG2 ***, DSG2 is a major receptor of HAdV-B55 causing adult CAP. Our finding is important for better understanding of interactions between adenoviruses and host cells and may shed light on the development of new drugs that can interfere with these processes as well as for the development of potent prophylactic vaccines.

关键词： Human adenovirus type 55(HAdV-B55) Severe community-acquired pneumonia Adenovirus receptor Desmoglein 2(DSG2)

在线全文

学校读者我要写书评

暂无评论

中国农村土地产权权能弱化论析

四川大学学报（哲学社会科学版） 2013年第6期 108-115页

作者：郑和平段龙龙西南交通大学公共管理学院四川成都610031 西南交通大学经济管理学院四川成都610031

当前中国农村集体土地产权权能弱化趋势凸显,主要体现在农村集体土地终极所有权主体虚置导致的产权权能弱化和所有权裂变情境下农民土地承包经营权权能保障不足两个方面,究其根本动因主要源于政治制度变迁与政策变革的双重影响、农村集... 详细信息

当前中国农村集体土地产权权能弱化趋势凸显,主要体现在农村集体土地终极所有权主体虚置导致的产权权能弱化和所有权裂变情境下农民土地承包经营权权能保障不足两个方面,究其根本动因主要源于政治制度变迁与政策变革的双重影响、农村集体土地所有权权能体系残缺和产权保障政策不全、行政强权侵犯产权三个层面,因而必须从强化土地产权、确权改革、构筑新型集体经济治理机制和推进行政体制改革,规范政府公权力运行三个方位重构农村集体土地产权权能在生产、流通与分配三个环节所体现的排他性职能。

关键词：农村土地所有权产权土地承包经营权集体经济组织

在线全文

学校读者我要写书评

暂无评论

某水电站右岸断层施工稳定性研究

水力发电 2010年第10期36卷 13-15页

作者：郑和平杨健中国葛洲坝集团第二工程有限公司四川成都610091 中国水电工程顾问集团公司北京100120

以某水电站大坝右岸f13断层置换处理为例,运用FLAC3D软件分析f13断层防渗斜井处理效果和斜井施工期间的稳定性。结果表明,f13断层防渗处理采用斜井置换,通过锚喷支护、混凝土衬砌、回填低热微膨胀混凝土处理后,完全可以满足大坝坝基和... 详细信息

以某水电站大坝右岸f13断层置换处理为例,运用FLAC3D软件分析f13断层防渗斜井处理效果和斜井施工期间的稳定性。结果表明,f13断层防渗处理采用斜井置换,通过锚喷支护、混凝土衬砌、回填低热微膨胀混凝土处理后,完全可以满足大坝坝基和抗力体防渗稳定要求。

关键词： FLAC 稳定性分析断层防渗处理

在线全文

学校读者我要写书评

暂无评论

纳米蒙脱土复合降凝剂的制备及性能评价

精细化工 2022年第11期39卷 2364-2370页

作者：罗晓雯郑和平邹永鑫唐建华四川大学化学工程学院四川成都610065 四川煤炭产业集团有限责任公司四川成都610091

以丙烯酸十八酯、马来酸酐、苯乙烯为原料,偶氮二异丁腈为引发剂,通过自由基聚合反应制备了一种传统共聚物降凝剂(PSMS);为提升PSMS降凝效果及稳定性,选用十六烷基三甲基溴化铵改性后的蒙脱土(OMMT)与共聚物PSMS进行插层复合制备纳米复... 详细信息

以丙烯酸十八酯、马来酸酐、苯乙烯为原料,偶氮二异丁腈为引发剂,通过自由基聚合反应制备了一种传统共聚物降凝剂(PSMS);为提升PSMS降凝效果及稳定性,选用十六烷基三甲基溴化铵改性后的蒙脱土(OMMT)与共聚物PSMS进行插层复合制备纳米复合降凝剂PSMS/OMMT,将其应用于克拉玛依原油进行效果评价,并借助偏光显微镜(POM)和其他测试初步阐明了降凝机理。结果表明,使用原油质量0.1%的PSMS/OMMT[其中OMMT加入量为10%(以PSMS质量为基准,下同)]可使原油凝点降幅达25℃,降黏率达65.7%(20℃下);与PSMS相比,使用量减少1/3、凝点降低3℃、降黏率提升约10%(20℃下),并且抗老化性能也得到大幅提升。

关键词：原油降凝剂纳米材料插层复合蒙脱土性能评价油田化学品

在线全文

学校读者我要写书评

暂无评论

河南省产业结构调整节能研究(上)

科技创业月刊 2010年第10期23卷 5-7页

作者：郑和平濮阳市公路管理局河南濮阳457000

聚焦于三次产业、产业内部结构调整,研究它与能源消耗强度下降(能源节约)的方向、困难、措施。分析表明:河南省产业结构虽经历了20多年的调整,在现有的产业结构框架下,经济增长与能源消耗呈倒U型曲线,且调整尚未到达转折点,短期内能源... 详细信息

聚焦于三次产业、产业内部结构调整,研究它与能源消耗强度下降(能源节约)的方向、困难、措施。分析表明:河南省产业结构虽经历了20多年的调整,在现有的产业结构框架下,经济增长与能源消耗呈倒U型曲线,且调整尚未到达转折点,短期内能源消耗量随着经济增长将持续增长,但从长远来看,一旦河南省进入工业化后期或者后工业化时期,产业结构调整与优化肯定能降低能源强度。提出了产业结构调整的节能建议:一是适应需求结构的变化调整产业结构;二是优先扶持发展选择符合新型工业化特点的产业,改造和提升传统支柱产业;三是大力推进"一个载体、三个体系建设";四是通过促消费、引民资、扩出口,加大第三产业发展的力度、强度。

关键词：能源消耗能源消耗强度节能产业结构结构调整

维普期刊数据库博看期刊

ICU患者气管插管的心血管应激反应与不同麻醉手段相关性

在线全文

学校读者我要写书评

暂无评论

中国医药科学 2014年第23期4卷 81-82,85页

作者：郑和平福建省同民医院重症医学科福建厦门361101

目的对比不同麻醉方法应用于ICU患者气管插管的效果,观察心血管应激反应,探寻最佳麻醉疗法。方法选取我院治疗的60例ICU患者为研究对象,随机分为观察组与对照组,均采用气管插管诱导,静脉麻醉。观察组予5μg/kg芬太尼、1.5mg/kg丙泊酚、0... 详细信息

目的对比不同麻醉方法应用于ICU患者气管插管的效果,观察心血管应激反应,探寻最佳麻醉疗法。方法选取我院治疗的60例ICU患者为研究对象,随机分为观察组与对照组,均采用气管插管诱导,静脉麻醉。观察组予5μg/kg芬太尼、1.5mg/kg丙泊酚、0.1mg/kg维库溴铵、1mg/kg氯胺酮联合使用;对照组予5μg/kg芬太尼、1.5mg/kg丙泊酚、0.1mg/kg维库溴铵、0.1mg/kg咪达唑仑联合使用,对比观察两组麻醉前后血液动力学变化。结果与麻醉前相比,观察组与对照组气管插管麻醉诱导后血压、心率均有明显改变,其差异有统计学意义(P<0.05)。观察组血压、心率波动幅度明显小于对照组,其差异有统计学意义(P<0.05)。结论氯胺酮联合丙泊酚、芬太尼应用于气管插管麻醉诱导患者,效果显著,安全性高,具有临床应用价值。

关键词：心血管应激反应麻醉重症监护病房气管插管