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Robot-assisted laparoscopic pyeloureterostomy for ureteropelvic junction rupture sustained in a traffic accident:A case report

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World Journal of Clinical Cases 2020年第22期8卷 5802-5808页

作者： Si Hyun Kim Woong Bin Kim Jae heon Kim Sang Wook lee Department of Urology Soonchunhyang University Cheonan HospitalCheonan 31151South Korea Department of Urology Soonchunhyang University Bucheon HospitalBucheon 14584South Korea Department of Urology Soonchunhyang University Seoul HospitalSoonchunhyang University Medical CollegeSeoul 04401South Korea Department of Urology Soonchunhyang University Bucheon HospitalSoonchunhyang University School of MedicineBucheon 14584South Korea

BACKGROUND Ureteral reconstruction is a highly technical type of laparoscopic or open *** incidence of ureteral injury is low;however,ureteral injuries tend to be *** surgery for urinary reconstructive surgery is growing in popularity,which has made procedures such as pyeloplasty,ureteroureterostomy,and ureteroneocystostomy possible,with minimal damage to the *** the best of our knowledge,this is the first report of robot-assisted laparoscopic pyeloureterostomy in Korea,in a 17-year-old female patient with a ureteral *** SUMMARY The patient,a 17-year-old girl without previous medical history,was presented at the emergency room and complained of abdominal and back *** in the right upper quadrant was observed on physical *** in the right perirenal space was observed without abdominal organ injuries on the initial enhanced abdomen computed tomography(CT)*** injury was not suspected at this *** patient was stabilized via conservative treatment,but complained of right flank pain 3 wk later and revisited the emergency *** enhanced abdominal CT scan revealed a huge urinoma in the right perirenal space with hydronephrosis of the right *** and antegrade pyelography were *** and discontinuity of the ureter were found.A rupture of the ureteropelvic junction was diagnosed and reconstructive surgery was *** 3 mo,the patient did not complain of any symptoms without any abnormal radiologic *** This case report discusses the safety and effectiveness of this minimal invasive procedure as an alternative to conventional open or laparoscopic surgery.

关键词： Robot surgical procedure Ureteral injuries Minimal invasive surgical procedures Reconstructive surgical procedures Urology Case report

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Diagnostic value of PIVKA-Ⅱ and alpha-fetoprotein in hepatitis B virus-associated hepatocellular carcinoma

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World Journal of Gastroenterology 2015年第13期21卷 3928-3935页

作者： Seung In Seo Hyoung Su Kim Won Jin Kim Woon Geon Shin Doo Jin Kim Kyung Ho Kim Myoung Kuk Jang Jin heon lee Joo Seop Kim Hak Yang Kim Dong Joon Kim Myung Seok lee Choong Kee Park Department of Internal Medicine Hallym University Medical CenterSeoul 134-701South Korea Digestive Disease Center Hallym University Medical CenterSeoul 134-701South Korea Department of Surgery Hallym University Medical CenterSeoul 134-701South Korea

AIM: To determine the cutoff values and to compare the diagnostic role of alpha-fetoprotein(AFP) and prothrombin induced by vitamin K absence-Ⅱ(PIVKA-Ⅱ) in chronic hepatitis B(CHB).METHODS: A total of 1255 patients with CHB, including 157 patients with hepatocellular carcinoma(HCC), 879 with non-cirrhotic CHB and 219 with cirrhosis without HCC, were retrospectively enrolled. The areas under the receiver operating characteristic(AUROC) curves of PIVKA-Ⅱ, AFP and their combination were calculated and ***: The optimal cutoff values for PIVKA-Ⅱ and AFP were 40 m AU/m L and 10 ng/m L, respectively, for the differentiation of HCC from nonmalignant CHB. The sensitivity and specificity were 73.9% and 89.7%, respectively, for PIVKA-Ⅱ and 67.5% and 90.3% for AFP, respectively. The AUROC curves of both PIVKA-Ⅱ and AFP were not significantly different(0.854 vs 0.853, P = 0.965) for the differentiation of HCC from nonmalignant CHB, whereas the AUROC of PIVKA-Ⅱ was significantly better than that of AFP in patients with cirrhosis(0.870 vs 0.812, P = 0.042). When PIVKA-Ⅱ and AFP were combined, the diagnostic power improved significantly compared to either AFP or PIVKA-Ⅱ alone for the differentiation of HCC from nonmalignant CHB(P < 0.05), especially when cirrhosis was present(P < 0.05).CONCLUSION: Serum PIVKA-Ⅱ might be a better tumor marker than AFP, and its combination with AFP may enhance the early detection of HCC in patients with CHB.

关键词： Hepatitis B virus Hepatocellular carcinoma Alpha-f

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Pediatric appendicitis with appendicolith often presents with prolonged abdominal pain and a high risk of perforation

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World Journal of Pediatrics 2018年第2期14卷 184-190页

作者： Hee Mang Yoon Jung heon Kim Jong Seung lee Jeong-Min Ryu Dae Yeon Kim Jeong-Yong lee Department of Radiology and Research Institute of Radiology Asan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505South Korea Department of Emergency Medicine Asan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505South Korea Department of Pediatric Surgery Asan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505South Korea Department of Pediatrics Asan Medical CenterUniversity of Ulsan College of Medicine88Olympic-ro 43-gilSongpa-guSeoul 05505South Korea

Background Appendicolith can cause appendiceal obstruction and acute *** high prevalence may be related to the high perforation rate in pediatric *** study assessed the characteristics of appendicolith and its clinical significance in pediatric *** A retrospective study was performed among children and adolescents younger than 17 years who were preopera-tively diagnosed with appendicitis in the pediatric emergency department(ED).A total of 269 patients with a mean age of 9.98±3.37 years were *** features and contrast-enhanced computed tomography findings were *** Among the 269 patients,147(54.6%)had appendicoliths,with a mean maximal diameter of 5.21±2.34 ***-pared to the no appendicolith group,the appendicolith group demonstrated more prolonged abdominal pain(≥48 hours)before the ED visit(23.1%vs.11.5%;P=0.013),clinical features of severe appendicitis(presence of fever,vomiting,posi-tive urine ketone,and increased C-reactive protein),and higher rate of perforation(43.5%vs.9.8%;P<0.001).Multivariate risk factor analysis for perforated appendicitis in the appendicolith group revealed that maximal diameter of 5 mm or more in the appendicolith(adjusted odds ratio[aOR]2.919;95%CI 1.325-6.428,P=0.008)and proximal collapse adjacent to the appendicolith(aOR 2.943;95%CI 1.344-6.443,P=0.007)were *** Pediatric appendicitis with appendicolith often presents with prolonged abdominal pain and severe clinical conditions with a high risk of perforation.

关键词： Appendicitis Appendicolith Computed tomography Pediatrics Risk factors

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A Simple Method for Grain Refinement of Pure Aluminium

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Journal of Materials Science & Technology 2003年第2期19卷 187-188页

作者： Dae-heon Joo, Jeong-Keun lee and Myung-Ho KimSchool of Materials Science and Engineering, Inha University, Inchon 402-751, Korea Sch. of Mat. Sci. and Eng. Inha Univ. Inchon 402-75 South Korea

In order to produce the fully equiaxed and fine grained pure Al, a simple casting process that used cooling slope was examined and compared with conventional casting process under same casting conditions. By using cooling slope, grains over the whole section of castings were suddenly refined and ability of grain refinement kept up at very high mold temperature up to 550癈 in examined casting conditions.

关键词： Equiaxed microstructure Heterogeneous nucleation Grain refinement

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Interactions between Transmembrane Helices within Monomers of the Aquaporin AtPIP2;1 Play a Crucial Role in Tetramer Formation

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Molecular Plant 2016年第7期9卷 1004-1017页

作者： Yun-Joo Yoo Hyun Kyung lee Wonhee Han Dae heon Kim Myoung Hui lee Jouhyun Jeon Dong Wook lee Junho lee Yongjik lee Juhun lee Jin Seok Kim Yunje Cho Jin-Kwan Han Inhwan Hwang School of Interdisciplinary Bioscience and Bioengineering Pohang University of Science and Technology Pohang 790-784 Korea Department of Life Sciences Pohang University of Science and Technology Pohang 790-784 Korea Department of Biology Sunchon National University Sunchon 57922 Korea Division of Integrative Biosciences and Biotechnology Pohang University of Science and Technology Pohang 790-784 Korea

Aquaporin （AQP） is a water channel protein found in various subcellular membranes of both prokaryotic and eukaryotic cells. The physiological functions of AQPs have been elucidated in many organisms. However, understanding their biogenesis remains elusive, particularly regarding how they assemble into tetramers. Here, we investigated the amino acid residues involved in the tetramer formation of the Arabidopsis plasma membrane AQP AtPIP2;1 using extensive amino acid substitution mutagenesis. The mutant proteins V41A/ E44A, F51A/L52A, F87A/191A, F92A/193A, V95A/Y96A, and H216A/L217A, harboring alanine substitutions in the transmembrane （TM） helices of AtPIP2;1 polymerized into multiple oligomeric complexes with a vari- able number of subunits greater than four. Moreover, these mutant proteins failed to traffic to the plasma membrane, instead of accumulating in the endoplasmic reticulum （ER）. Structure-based modeling revealed that these residues are largely involved in interactions between TM helices within monomers. These results suggest that inter-TM interactions occurring both within and between monomers play crucial roles in tetramer formation in the AtPIP2;1 complex. Moreover, the assembly of AtPIP2;1 tetramers is critical for their trafficking from the ER to the plasma membrane, as well as water permeability.

关键词： aquaporin AtPIP2 tetramer formation interaction between transmembrane helices

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The effect of sunblock against oxidative stress in farmers：a pilot study

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The Journal of Biomedical Research 2017年第4期31卷 344-349页

作者： Yong-Dae Kim Dong-Hyuk Yim Sang-Yong Eom Ji Yeoun lee heon Kim Center for Farmers' Safety and Health Chungbuk National University Hospital Cheongju Republic of Korea Department of Preventive Medicme College of Medwme Chungbuk Nattonal Umverszty Cheonglu Repubhc of Korea Department of Dermatology College of Medicine Chungbuk National University Cheongju Republic of Korea

Farmers are frequently exposed to ultraviolet（UV） radiation which causes various diseases by inducing oxidative *** study aimed to assess the effects of sunblock on oxidative stress in the ***-seven farmers were divided into two groups：those who wore sunblock for five days and those who did *** total antioxidant capacity（TAC） in urine,which is an antioxidant indicator,and 8-hydroxy-2-deoxyguanosine（8-OHdG） levels in urine,an oxidative stress indicator,were *** urinary TAC of sunblock users was significantly higher than that of non-users,but urinary 8-OHdG levels were not significantly *** after adjustment for potential confounders,urinary TAC was found to be markedly increased with sunblock *** results suggest that sunblock is effective in preventing oxidative stress among *** addition,they show that urinary TAC can be used as a good effect marker of oxidative stress caused by UV exposure.

关键词： farmers ultraviolet rays sunscreening agents oxidative stress total antioxidant capacity

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Development of triple-layered tablets containing laxatives with a hydrophilic polymer

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Asian Journal of Pharmaceutical Sciences 2016年第1期11卷 134-135页

作者： Woo heon Song Jin Seob Oh Kyung Soo lee Jun Sang Park GL PharmTech Corporation

Constipation is a common functional gastrointestinal disorder which has caused much discomfort affecting the quality of life. The prevalence of constipation in the general population is approximately 20%(1)Various kinds of laxatives were introduced such as bulking agent, stool softener, stimulant, and osmotic agent (2)Fixed dose combination with bisacodyl as a stimulant and docusate sodium as a stool softener, Ducolax STM, was developed as enteric coated tablets targeting colon.

关键词： Hydrophilic polymer Sodium carboxymethylcellulose Bisacodyl Triple-layered tablet

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Phase-controlled synthesis of thermally stable nitrogen-doped carbon supported iron catalysts for highly efficient Fischer-Tropsch synthesis

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Nano Research 2019年第10期12卷 2568-2575页

作者： Jin Hee lee Hack-Keun lee Dong Hyun Chun Hyunkyung Choi Geun Bae Rhim Min Hye Youn heondo Jeong Shin Wook Kang Jung-ll Yang heon Jung Chui Sung Kim Ji Chan Park Clean Fuel Laboratory Korea Institute of Energy ResearchDaejeon 34129Republic of Korea Department of Chemical Engineering University of SeoulSeoul 02504Republic of Korea Advanced Energy and System Technology University of Science and TechnologyDaejeon 34113Republic of Korea Department of Physics Kookmin UniversitySeoul 02707Republic of Korea

Iron-based nan oparticles with un iform and high particle dispersi on,which are supported on carb on structures,have been used for various ***,their preparation still suffers from complicated synthesis involving multiple steps and from the high price of precursors and solve *** the prese nt work,a new carbon en capsulated iron-carbide nano particle supported on n itroge rvdoped porous carbon(Fe5C2@C/NPC)structure was *** was made using a simple solid-state reaction with sequential thermal ***5C2@C/NPC is a highly active and stable catalyst for the high-temperature Fischer-Tropsch synthesis *** showed very high hydrocarbon productivity(4.71 gHc gcat^-1·h^-1)with high CO conversions(up to 96%).

关键词： iron-carbide one-pot synthesis nitrogen-doped graphene Fischer-Tropsch synthesis Mdssbauer spectroscopy

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UV light driven high-performance room temperature surface acoustic wave NH_(3) gas sensor using sulfur-doped g-C_(3)N_(4) quantum dots

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Nano Research 2023年第5期16卷 7682-7695页

作者： Kedhareswara Sairam Pasupuleti Sourabh S.Chougule Devthade Vidyasagar Na-hyun Bak Namgee Jung Young-heon Kim Jong-Hee lee Song-Gang Kim Moon-Deock Kim Department of Physics Chungnam National University99 Daehak-roYuseong-guDaejeon 34134Republic of Korea Graduate School of Energy Science and Technology(GEST) Chungnam National University99 Daehak-roYuseong-guDaejeon 34134Republic of Korea Department of Materials Science and Engineering Kyungpook National University80 Daehak-roBuk-guDaegu 41566Republic of Korea Graduate School of Analytical Science and Technology Chungnam National University99 Daehak-roYuseong-guDaejeon 34134Republic of Korea Department of Digital Agricultural Promotion Agricultural Cooperative UniversityGoyang-siGyeonggi-do 10292Republic of Korea Department of Smart Information Technology Joonbu University305 Donghen-roGoyangKyunggi-do 10279Republic of Korea Institute of Quantum Systems(IQS) Chungnam National University99 Daehak-roYuseong-guDaejeon 34134Republic of Korea

Nanomaterials integrated surface acoustic wave(SAW)gas sensing technology has emerged as a promising candidate for realtime toxic gas sensing applications for environmental and human health ***,the development of novel chemical interface based on two-dimensional(2D)sensing materials for SAW sensors for the rapid and sensitive detection of NH_(3)gas at room temperature(RT)still remains ***,we report a highly selective RT NH_(3)gas sensor based on sulfur-doped graphitic carbon nitride quantum dots(S@g-C_(3)N_(4)QD)coated langasite(LGS)SAW sensor with enhanced sensitivity and recovery rate under ultraviolet(UV)***,the sensitivity of the S@g-C_(3)N_(4)QD/LGS SAW sensor to NH_(3)(500 ppb)at RT is dramatically enhanced by~4.5-fold with a low detection limit(~85 ppb),high selectivity,excellent reproducibility,fast response/recovery time(70 s/79 s)under UV activation(365 nm)as compared to dark ***,the proposed sensor exhibited augmented NH_(3)detection capability across the broad range of relative humidity(20%–80%).Such remarkable gas sensing performances of the as-prepared sensor to NH_(3)are attributed to the high surface area,enhanced functional groups,sulfur defects,UV photogenerated charge carriers,facile charge transfer in the S@g-C_(3)N_(4)QD sensing layer,which further helps to improve the gas molecules adsorption that causes the increase in conductivity,resulting in larger frequency *** gas sensing mechanism of S@g-C_(3)N_(4)QD/LGS SAW sensor is ascribed to the enhanced electroacoustic effect,which is supported by the correlation of resistive type and COMSOL Multiphysics simulation *** envisage that the present work paves a promising strategy to develop the next generation 2D g-C_(3)N_(4)based high responsive RT SAW gas sensors.

关键词： two-dimensional graphitic carbon nitride(2D g-C_(3)N_(4)) sulfur doping quantum dots surface acoustic wave(SAW)sensor NH_(3)gas electroacoustic effect

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Endovascular treatment of traumatic renal artery pseudoaneurysm with a Stanford type A intramural haematoma:A case report

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World Journal of Clinical Cases 2022年第27期10卷 9760-9767页

作者： Yook Kim Jin Young lee Jin Suk lee Jin Bong Ye Se heon Kim Young Hoon Sul Su Young Yoon Jung Hee Choi Hanlim Choi Department of Radiology Chungbuk National University HospitalCheongju-si 28644Chungcheongbuk-doSouth Korea Department of Trauma Surgery Chungbuk National University HospitalCheongju-si 28644Chungcheongbuk-doSouth Korea Department of Trauma Surgery College of MedicineChungbuk National UniversityCheongju-si 28644Chungcheongbuk-doSouth Korea Cardiovascular and Thoracic Surgery Chungbuk National University HospitalCheongju-si 28644Chungcheongbuk-doSouth Korea Anesthesiology and Pain Medicine Chungbuk National University HospitalCheongju-si 28644Chungcheongbuk-doSouth Korea Department of Surgery Chungbuk National University HospitalCheongju-si 28644Chungcheongbuk-doSouth Korea

BACKGROUND Aortic intramural hematoma(IMH) associated with aortic branch tear and intramurally located pseudoaneurysm after blunt trauma has not been ***,we report a case of progressive type A aortic IMH associated with a pseudoaneurysm arising from the injured proximal renal artery after blunt *** SUMMARY During logging operations,a 66-year-old man experienced blunt force trauma after being injured by a fallen *** arrived at our trauma center with a left flank pain *** tomography(CT) revealed a pseudoaneurysm arising from the proximal renal artery(localized within the aortic media) and Stanford type A IMH.A covered stent was deployed along the left main renal artery,bridging the pseudoaneurysm and covering the parent artery,successfully excluding the pseudoaneurysm as confirmed using ***,although the degree of the pseudoaneurysm decreased,follow-up CT revealed remnant pseudoaneurysm,likely caused by an ***,a covered stent was additionally installed through the previously deployed covered *** exclusion of the pseudoaneurysm was confirmed using final *** the 7-mo follow-up CT scan,the IMH and pseudoaneurysm completely disappeared with no evidence of stent-related *** Endovascular treatment such as stent-graft placement can be an effective and safe treatment for traumatic renal artery injury.

关键词： Aortic intramural hematoma Blunt trauma Intimomedial tear Renal arterial injury Stent-graft Case report

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