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Collagen fleece(Tachosil®)for treating testis torsion:A case report

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World Journal of Clinical Cases 2023年第18期11卷 4306-4312页

作者： Ki Min kim Jae heon kim Department of Urology Soonchunhayng University Seoul HospitalSeoul 04410South Korea

BACKGROUND Testicular torsion is an emergent disease in urology,and there has been discussion of the treatment of testicular *** decompression has been established as a critical treatment for testicular compartment syndrome(TCS),which occurs after detorsion in a patient who is diagnosed with testis *** now,testicular fasciotomy and incision of tunica albuginea with tunica vaginalis flap(TVF)graft have been suggested for decompression,and some studies about the efficacy of TVF were ***,this method is time consuming and needs meticulous technique,so other methods such as orchio-septopexy are *** objective of this clinical case report was to propose new surgical method using collagen fleece(Tachosil®)instead of tunica vagina *** SUMMARY A 5-year-old boy with scrotal pain visited our hospital 24 h after symptom *** history taking,physical examination,and scrotum ultrasonography,he was diagnosed with testis *** surgery was performed after *** the incision of scrotum and fasciotomy,we covered his tunica albuginea with collagen fleece called Tachosil®instead of covering with *** Short-term follow-up showed normal blood flow in testis without a *** is the first case report of using Tachosil®in testicular torsion surgery,and its advantages were already reported in other surgeries like Peyronie’s *** case suggests this new technique is an appropriate method because of its advantages including its cost-effective and time-saving *** main limitation is the short follow-up,so more studies are needed to provide a high level of evidence about its efficacy and safety.

关键词： Testicular torsion Testicular compartment syndrome Collagen fleece Tachosil® Case report

UV light driven high-performance room temperature surface acoustic wave NH_(3) gas sensor using sulfur-doped g-C_(3)N_(4) quantum dots

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Nano Research 2023年第5期16卷 7682-7695页

作者： Kedhareswara Sairam Pasupuleti Sourabh S.Chougule Devthade Vidyasagar Na-hyun Bak Namgee Jung Young-heon kim Jong-Hee Lee Song-Gang kim Moon-Deock kim Department of Physics Chungnam National University99 Daehak-roYuseong-guDaejeon 34134Republic of Korea Graduate School of Energy Science and Technology(GEST) Chungnam National University99 Daehak-roYuseong-guDaejeon 34134Republic of Korea Department of Materials Science and Engineering Kyungpook National University80 Daehak-roBuk-guDaegu 41566Republic of Korea Graduate School of Analytical Science and Technology Chungnam National University99 Daehak-roYuseong-guDaejeon 34134Republic of Korea Department of Digital Agricultural Promotion Agricultural Cooperative UniversityGoyang-siGyeonggi-do 10292Republic of Korea Department of Smart Information Technology Joonbu University305 Donghen-roGoyangKyunggi-do 10279Republic of Korea Institute of Quantum Systems(IQS) Chungnam National University99 Daehak-roYuseong-guDaejeon 34134Republic of Korea

Nanomaterials integrated surface acoustic wave(SAW)gas sensing technology has emerged as a promising candidate for realtime toxic gas sensing applications for environmental and human health ***,the development of novel chemical interface based on two-dimensional(2D)sensing materials for SAW sensors for the rapid and sensitive detection of NH_(3)gas at room temperature(RT)still remains ***,we report a highly selective RT NH_(3)gas sensor based on sulfur-doped graphitic carbon nitride quantum dots(S@g-C_(3)N_(4)QD)coated langasite(LGS)SAW sensor with enhanced sensitivity and recovery rate under ultraviolet(UV)***,the sensitivity of the S@g-C_(3)N_(4)QD/LGS SAW sensor to NH_(3)(500 ppb)at RT is dramatically enhanced by~4.5-fold with a low detection limit(~85 ppb),high selectivity,excellent reproducibility,fast response/recovery time(70 s/79 s)under UV activation(365 nm)as compared to dark ***,the proposed sensor exhibited augmented NH_(3)detection capability across the broad range of relative humidity(20%–80%).Such remarkable gas sensing performances of the as-prepared sensor to NH_(3)are attributed to the high surface area,enhanced functional groups,sulfur defects,UV photogenerated charge carriers,facile charge transfer in the S@g-C_(3)N_(4)QD sensing layer,which further helps to improve the gas molecules adsorption that causes the increase in conductivity,resulting in larger frequency *** gas sensing mechanism of S@g-C_(3)N_(4)QD/LGS SAW sensor is ascribed to the enhanced electroacoustic effect,which is supported by the correlation of resistive type and COMSOL Multiphysics simulation *** envisage that the present work paves a promising strategy to develop the next generation 2D g-C_(3)N_(4)based high responsive RT SAW gas sensors.

关键词： two-dimensional graphitic carbon nitride(2D g-C_(3)N_(4)) sulfur doping quantum dots surface acoustic wave(SAW)sensor NH_(3)gas electroacoustic effect

Recent Advances in Patterning Strategies for Full‑Color Perovskite Light‑Emitting Diodes

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Nano-Micro Letters 2024年第3期16卷 99-137页

作者： Gwang heon Lee Kiwook kim Yunho kim Jiwoong Yang Moon Kee Choi Graduate School of Semiconductor Materials and Devices Engineering Center for Future Semiconductor Technology(FUST)Ulsan National Institute of Science and Technology(UNIST)Ulsan 44919Republic of Korea Department of Energy Science and Engineering Daegu Gyeongbuk Institute of Science and Technology(DGIST)Daegu 42988Republic of Korea Energy Science and Engineering Research Center Daegu Gyeongbuk Institute of Science and Technology(DGIST)Daegu 42988Republic of Korea Department of Materials Science and Engineering Ulsan National Institute of Science and Technology(UNIST)Ulsan 44919Republic of Korea Center for Nanoparticle Research Institute for Basic Science(IBS)Seoul 08826Republic of Korea

Metal halide perovskites have emerged as promising light-emitting materials for next-generation displays owing to their remarkable material characteristics including broad color tunability,pure color emission with remarkably narrow bandwidths,high quantum yield,and solution *** recent advances have pushed the luminance efficiency of monochromic perovskite light-emitting diodes(PeLEDs)to their theoretical limits,their current fabrication using the spincoating process poses limitations for fabrication of full-color *** integrate PeLEDs into full-color display panels,it is crucial to pattern red–green–blue(RGB)perovskite pixels,while mitigating issues such as cross-contamination and reductions in luminous ***,we present state-of-the-art patterning technologies for the development of full-color ***,we highlight recent advances in the development of efficient ***,we discuss various patterning techniques of MPHs(i.e.,photolithography,inkjet printing,electron beam lithography and laserassisted lithography,electrohydrodynamic jet printing,thermal evaporation,and transfer printing)for fabrication of RGB pixelated *** patterning techniques can be classified into two distinct approaches:in situ crystallization patterning using perovskite precursors and patterning of colloidal perovskite *** review highlights advancements and limitations in patterning techniques for PeLEDs,paving the way for integrating PeLEDs into full-color panels.

关键词： Perovskite Light-emitting diode Full-color display High-resolution patterning Electroluminescence

AAV6 as an effective gene delivery vector for prolonged transgene expression in intervertebral disc cells in vivo

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Genes & Diseases 2022年第4期9卷 1074-1085页

作者： Chi heon kim Colleen Oliver Hamid Dar Hicham Drissi Steven M.Presciutti Department of Orthopaedics Emory University School of MedicineAtlantaGA 30329USA Atlanta Veteran Affairs Medical Center DecaturGA 30030USA

Intervertebral disc degeneration is the main contributor to low back pain,now the leading cause of disability *** transfer,either in a therapeutic attempt or in basic research to understand the mechanisms of disc degeneration,is a fascinating and promising tool to manipulate the complex physiology of the *** vectors based on the adeno-associated virus(AAV)have emerged as powerful transgene delivery vehicles yet a systematic investigation into their respective tropism,transduction efficiency,and relative toxicity have not yet been performed in the disc in ***,we used in vivo bioluminescence imaging to systematically compare multiple AAV serotypes,injection volumes,titers,promoters,and luciferase reporters to determine which result in high transduction efficiency of murine nucleus pulposus(NP)cells in *** find that AAV6 using a CAG promoter to drive transgene expression,delivered into the NP of murine caudal discs at a titer of 1011 GC/mL,provides excellent transduction efficiency/kinetics and low toxicity in *** also show,for the first time,that the transduction of NP cells can be significantly boosted in vivo by the use of small cell permeabilization ***,to our knowledge,we are the first to demonstrate the use of optical tissue clearing and three-dimensional lightsheet microscopy in the disc,which was used to visualize fine details of tissue and cell architecture in whole intact discs following AAV6 *** together,these data will contribute to the success of using AAV-mediated gene delivery for basic and translational studies of the IVD.

关键词： Adeno-associated virus Bioluminescence imaging Cell permeabilization peptide Intervertebral disc Lightsheet microscopy Nucleus pulposus transduction Tissue clearing

Biochar improves soil properties and corn productivity under drought conditions in South Korea

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Biochar 2023年第1期5卷 1148-1158页

作者： Jae-Hyuk Park Jin-Ju Yun Seong-heon kim Jong-Hwan Park Bharat Sharma Acharya Ju-Sik Cho Se-Won Kang Department of Agricultural Chemistry Sunchon National UniversitySuncheon 57922Republic of Korea Division of Soil and Fertilizer National Institute of Agricultural SciencesRDAWanju 55365Republic of Korea Department of Life Resources Industry Dong-A UniversityBusan 49315Republic of Korea Rodale Institute Southeast Organic CenterChattahoochee HillsGA 30268USA Department of Agricultural Life Sciences Sunchon National UniversitySuncheon 57922Republic of Korea

Biochar has been shown to improve soil properties and plant productivity in soils with inherently low ***,little has been reported for upland corns under dry and wet precipitation *** study investigates the effect of biochar addition on a range of soil physicochemical,biological,and hydrological properties,and corn growth and productivity under agrometeorological drought and wet ***,experiments were laid out in a randomized complete block design with three replications at two sites during 2017 and 2018 in South *** included(i)CN:control(ii)IF:inorganic fertilizer(N-P-K)at 145-30-60 kg ha^(−1);(iii)BS:barley straw at 5 t ha^(−1);(iv)CWBC:corn waste biochar at 5 t ha^(−1);(v)CWBC+IF:corn waste biochar+inorganic fertilizer;(vi)CWBC+BS:corn waste biochar+barley *** year 2017 was relatively dry,whereas the year 2018 was *** drought conditions in the year 2017,biochar facilitated soil water ***,higher precipitation in 2018 increased the quantity and distribution of soil water and nutrients in the top 15 *** reduced soil bulk density,and increased porosity,cation exchange capacity and total organic carbon in both years but increased total bacterial counts during the dry year *** population was generally higher under wet ***,more soil CO_(2) was emitted in the wet year than in the dry *** further indicated that biochar can enhance corn biomass and grain yield regardless of precipitation *** grain index was,however,affected by rainfall and was significantly different across treatments in the year 2018 *** biomass,grain yield,and grain index were highest in CWBC+IF treatment and lowest under CN ***,biochar addition appeared to improve soil quality and soil conditioning effects in the drought and wet years,ameliorating soil and plant ***,biochar can improve water and nutrients storage,availability,and uptake,and

关键词： Biochar Drought Precipitation Soil CO_(2)

Endovascular treatment of traumatic renal artery pseudoaneurysm with a Stanford type A intramural haematoma:A case report

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World Journal of Clinical Cases 2022年第27期10卷 9760-9767页

作者： Yook kim Jin Young Lee Jin Suk Lee Jin Bong Ye Se heon kim Young Hoon Sul Su Young Yoon Jung Hee Choi Hanlim Choi Department of Radiology Chungbuk National University HospitalCheongju-si 28644Chungcheongbuk-doSouth Korea Department of Trauma Surgery Chungbuk National University HospitalCheongju-si 28644Chungcheongbuk-doSouth Korea Department of Trauma Surgery College of MedicineChungbuk National UniversityCheongju-si 28644Chungcheongbuk-doSouth Korea Cardiovascular and Thoracic Surgery Chungbuk National University HospitalCheongju-si 28644Chungcheongbuk-doSouth Korea Anesthesiology and Pain Medicine Chungbuk National University HospitalCheongju-si 28644Chungcheongbuk-doSouth Korea Department of Surgery Chungbuk National University HospitalCheongju-si 28644Chungcheongbuk-doSouth Korea

BACKGROUND Aortic intramural hematoma(IMH) associated with aortic branch tear and intramurally located pseudoaneurysm after blunt trauma has not been ***,we report a case of progressive type A aortic IMH associated with a pseudoaneurysm arising from the injured proximal renal artery after blunt *** SUMMARY During logging operations,a 66-year-old man experienced blunt force trauma after being injured by a fallen *** arrived at our trauma center with a left flank pain *** tomography(CT) revealed a pseudoaneurysm arising from the proximal renal artery(localized within the aortic media) and Stanford type A IMH.A covered stent was deployed along the left main renal artery,bridging the pseudoaneurysm and covering the parent artery,successfully excluding the pseudoaneurysm as confirmed using ***,although the degree of the pseudoaneurysm decreased,follow-up CT revealed remnant pseudoaneurysm,likely caused by an ***,a covered stent was additionally installed through the previously deployed covered *** exclusion of the pseudoaneurysm was confirmed using final *** the 7-mo follow-up CT scan,the IMH and pseudoaneurysm completely disappeared with no evidence of stent-related *** Endovascular treatment such as stent-graft placement can be an effective and safe treatment for traumatic renal artery injury.

关键词： Aortic intramural hematoma Blunt trauma Intimomedial tear Renal arterial injury Stent-graft Case report

Robot-assisted laparoscopic pyeloureterostomy for ureteropelvic junction rupture sustained in a traffic accident:A case report

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World Journal of Clinical Cases 2020年第22期8卷 5802-5808页

作者： Si Hyun kim Woong Bin kim Jae heon kim Sang Wook Lee Department of Urology Soonchunhyang University Cheonan HospitalCheonan 31151South Korea Department of Urology Soonchunhyang University Bucheon HospitalBucheon 14584South Korea Department of Urology Soonchunhyang University Seoul HospitalSoonchunhyang University Medical CollegeSeoul 04401South Korea Department of Urology Soonchunhyang University Bucheon HospitalSoonchunhyang University School of MedicineBucheon 14584South Korea

BACKGROUND Ureteral reconstruction is a highly technical type of laparoscopic or open *** incidence of ureteral injury is low;however,ureteral injuries tend to be *** surgery for urinary reconstructive surgery is growing in popularity,which has made procedures such as pyeloplasty,ureteroureterostomy,and ureteroneocystostomy possible,with minimal damage to the *** the best of our knowledge,this is the first report of robot-assisted laparoscopic pyeloureterostomy in Korea,in a 17-year-old female patient with a ureteral *** SUMMARY The patient,a 17-year-old girl without previous medical history,was presented at the emergency room and complained of abdominal and back *** in the right upper quadrant was observed on physical *** in the right perirenal space was observed without abdominal organ injuries on the initial enhanced abdomen computed tomography(CT)*** injury was not suspected at this *** patient was stabilized via conservative treatment,but complained of right flank pain 3 wk later and revisited the emergency *** enhanced abdominal CT scan revealed a huge urinoma in the right perirenal space with hydronephrosis of the right *** and antegrade pyelography were *** and discontinuity of the ureter were found.A rupture of the ureteropelvic junction was diagnosed and reconstructive surgery was *** 3 mo,the patient did not complain of any symptoms without any abnormal radiologic *** This case report discusses the safety and effectiveness of this minimal invasive procedure as an alternative to conventional open or laparoscopic surgery.

关键词： Robot surgical procedure Ureteral injuries Minimal invasive surgical procedures Reconstructive surgical procedures Urology Case report

Effects of ciglitazone and troglitazone on the proliferation of human stomach cancer cells

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World Journal of Gastroenterology 2009年第3期15卷 310-320页

作者： Chan Woo Cheon Dae Hwan kim Dong heon kim Yong Hoon Cho Jae Hun kim Department of Surgery School of MedicineMedical Research InstitutePusan National UniversityBusan 602-739South Korea

AIM:To determine the cytological and molecular effects of peroxisome proliferation-activated receptor(PPAR)-γ and PPAR-γ agonists on stomach cancer ***:To determine the proliferation-suppressive effects of troglitazone and ciglitazone,SNU-216 and SNU-668 stomach cancer cells were plated in media containing 40 μmol/L troglitazone and ciglitazone at a density of 1 × 104 cells/*** 3,5 and 7 d,the cells were counted with a *** assess the appearance of PPAR-γ,a reverse-transcription polymerase chain reaction analysis was *** day 7,Western blotting was used to determine the effects of troglitazone and ciglitazone on the expression of p21 and phosphorylated-ERK(pERK) *** cytometry analysis was used to determine which portion of the cell cycle was delayed when troglitazone was used to suppress cell *** order to clarify the mechanism underlying the activity of troglitazone,microarray analysis was ***:PPAR-γ was manifested in both SNU-216 and SNU-668 *** and troglitazone suppressed cell growth,and troglitazone was a stronger suppressor of stomach cancer cells than ciglitazone,an inducer of cell cycle arrest in the G1 ***-668 cells were also determined to be more sensitive to ciglitazone and troglitazone than SNU-216 *** troglitazone and ciglitazone were administered to stomach cancer cells,levels of p21 expression were increased,but ERK phosphorylation levels were *** GW9662,an antagonist of PPAR-γ,was applied in conjunction with ciglitazone and troglitazone,the cell growth suppression effect was *** gene transcription program revealed a variety of alterations as the consequence of troglitazone treatment,and multiple troglitazone-associated pathways were *** genes whose expression was increased by troglitazone treatment were associated with cell development,differentiation,signal transmission between cells,and cell adhesion,and were also associated

关键词： Peroxisome proliferating-activated receptor-γ Ciglitazone Troglitazone Stomach cancer cells

Adiponectin restores the obesity-induced impaired immunomodulatory function of mesenchymal stromal cells via glycolytic reprogramming

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Acta Pharmaceutica Sinica B 2024年第1期14卷 273-291页

作者： Duc-Vinh Pham Thi-Kem Nguyen Bao-Loc Nguyen Jong-Oh kim Jee-heon Jeong Inho Choi Pil-Hoon Park Department of Pharmacology Hanoi University of PharmacyHanoi 100000Viet Nam College of Pharmacy Yeungnam UniversityGyeongsan 38541Republic of Korea Department of Medical Biotechnology Yeungnam UniversityGyeongsan 38541Republic of Korea Research Institute of Cell Culture Yeungnam UniversityGyeongsan 38541Republic of Korea Department of Precision Medicine School of MedicineSungkyunkwan UniversitySuwon 16419Republic of Korea

Obesity has been known to negatively modulate the life-span and immunosuppressive potential of mesenchymal stromal cells(MSC).However,it remains unclear what drives the compromised potency of obese *** this study,we examined the involvement of adiponectin,an adipose tissuederived hormone,in obesity-induced impaired therapeutic function of ***-induced obesity leads to a decrease in serum adiponectin,accompanied by impairment of survival and immunomodulatory effects of adipose-derived MSC(ADSC).Interestingly,priming with globular adiponectin(gAcrp)improved the immunomodulatory potential of obese *** effects were also observed in lean *** addition,gAcrp potentiated the therapeutic effectiveness of ADSC in a mouse model of DSS-induced ***,while obesity inhibited the glycolytic capacity of MSC,gAcrp treatment induced a metabolic shift toward glycolysis through activation of adiponectin receptor type 1/p38 MAPK/hypoxia inducible factor-1a *** findings suggest that activation of adiponectin signaling is a promising strategy for enhancing the therapeutic efficacy of MSC against immune-mediated disorders.

关键词： Adiponectin Adipose-derived stromal cells Colitis Glycolytic induction HIF1a Immunomodulation Mesenchymal stromal cells Obesity