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Success factors for high-quality oak forest(Quercus robur, Q. petraea) regeneration

Forest Ecosystems 2019年第4期6卷 367-383页

作者： Andreas M?lder Holger Sennhenn-Reulen Christoph Fischer hendrik rumpf Egbert Sch?nfelder Johannes Stockmann Ralf-Volker Nagel Department A (Forest Growth) Northwest German Forest Research Institute(NW-FVA)

Background: Within the framework of close-to-nature forestry, oak forest(Quercus robur, Q. petraea) regeneration techniques that consider both silvicultural and nature conservation demands have become a very important *** there are many experimental and local studies that aim at disentangling the relationships between different environmental and silvicultural factors and the success of oak regeneration, systematic supra-regional studies at the greater landscape level are missing so *** this background, the first objective(a) of this study was to present an efficient and sufficiently accurate sampling scheme for supra-regional forest regrowth inventories, which we applied to young oaks stands. The second, and major, objective(b) was to identify the crucial success factors for high-quality oak forest regeneration in northwest ***: Objective(a): Factors that have been identified as potentially crucial for the success or failure of oak regeneration were either included in a field inventory procedure or extracted from forest inventory databases. We found that the collected data were suitable to be analyzed in a three-step success model, which was aimed at identifying the crucial success factors for high-quality oak forest ***(b): Our modeling procedure, which included a Bayesian estimation approach with spike-and-slab priors,revealed that competitive pressure from the secondary tree species was the most decisive success factor;no competition, or low competition by secondary tree species appeared to be particularly beneficial for the success of high-quality oak regeneration. Also fencing and the absence of competitive vegetation(weeds, grass, bracken)seemed to be beneficial factors for the success of oak ***: Trusting in biological automation was found to be mostly useless regarding economically viable oak forest regeneration. To efficiently organize oak regeneration planning and silvicultural decision-ma

关键词： Close-to-nature forestry Competition Ecological continuity Forest inventory Forest management Plantplant interactions Quercus robur Quercus petraea Regeneration Silviculture

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Littoral landforms of Lake Hulun and Lake Buir(China and Mongolia):Wind-driven hydro-sedimentary dynamics and resulting clastics distribution

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Journal of Palaeogeography 2024年第2期13卷 309-326页

作者： Li Wang Mathieu Schuster Shi-Wei Xin Florin Zainescu Xin-Yu Xue Joep Storms Jan-hendrik May Alexis Nutz Helena van der Vegt Guilherme Bozetti Zai-Xing Jiang School of Energy Resources China University of Geosciences(Beijing)Beijing100083China Universite de Strasbourg CNRSENGEESInstitut Terre et Environnement de StrasbourgUMR 70635 Rue DescartesStrasbourgFrance Tamsag Mongolia(XIX)Ltd. PetroChinaDaqing 163000China CEREGE Aix-Marseille UniversitéCNESIRDCollege de FranceINRAAix en ProvenceFrance School of Marine Science Sun Yat-sen UniversityZhuhai 519083China Delft University of Technology Department of Geoscience and EngineeringDelfthe Netherlands School of Geography Earth and Atmospheric SciencesUniversity of Melbourne253 Elgin St.CarltonVIC 3053Australia Deltares Delfthe Netherlands SCMF Faculty of GeographyUniversity of Bucharest1 N.Balcescu Blv.BucharestRomania

Two rectangular-shaped lakes,Lake Hulun and Lake Buir,located at the boundary between China and Mongolia,only c.75 km apart and therefore experiencing similar wind fields,have been studied based on satellite images and field surveys in order to compare their geomorphological and sedimentological *** wind-driven hydrodynamics,which have a significant effect on the development of littoral landforms and on sediment distribution,have been discussed for the two similar lakes that experienced a prevailing wind perpendicular to their long axis.A conceptual model related to wind-driven water bodies and sediment distribution is ***-influenced to wave-dominated deltas,beaches,spits,and eolian dune deposits develop around these two lakes,with a strikingly similar distribution *** features locally inform the longshore drift and help reconstruct the water circulation induced by wind *** the NW prevailing wind regime,the spits developed on the SW coast with a NW—SE extension,which was influenced by the NW—SE longshore *** same influence was observed in the delta extension in the NE *** differences lie in the presence of fan deltas in the NW region of Lake Hulun,but not in Lake ***,the width of the beach and eolian deposits on the downwind coast of Lake Hulun is three times greater than that of Lake Buir which were caused by the differences in sediment supply and wind fetch between the two *** Hulun and Lake Buir provide two reliable examples to understand the relationship among the wind field,provenance,hydrodynamics,landforms,and asymmetrical distribution of clastics in elongated *** also represent relevant modern analogs,which may also be of guiding significance to wind-driven sand body prediction in lacustrine basins.

关键词： Wind-driven lakes Fetch Sedimentary facies Hydrodynamics Geomorphology Spits Shoreline Lake Hulun Lake Buir

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德国政府新设转化与创新署——应用科学大学特色化发展的新契机?

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应用型高等教育研究 2024年第1期9卷 32-36,56页

作者： hendrik Lackner 奥斯纳布吕克应用科学大学德国奥斯纳布吕克49076

德国政府试图通过设立一个新的国家科研资助机构来扩展国家资助体系下的科研、科研成果转化和创新生态系统。一直以来,德国科学基金会(DFG)都以资助德国综合性大学的基础研究为重。现在,新设立的德国转化与创新署(DATI)将特别向与企业... 详细信息

德国政府试图通过设立一个新的国家科研资助机构来扩展国家资助体系下的科研、科研成果转化和创新生态系统。一直以来,德国科学基金会(DFG)都以资助德国综合性大学的基础研究为重。现在,新设立的德国转化与创新署(DATI)将特别向与企业进行密切合作、扎根于地方的应用科学大学提供资助。随着该机构的成立,德国联邦政府致力于实现知识和创新更为迅速地转化为应用、转移到企业以及创建新的商业模式。文章介绍了德国转化与创新署的纲领和首个资助项目,将其与联邦飞跃式创新促进署(SPRIND)进行区分,并探讨了该机构的成立为应用科学大学的进一步特色化发展进程带来的机遇。

关键词：德国转化与创新署 DATI 应用导向应用科学大学

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A HybridManufacturing ProcessMonitoringMethod Using Stacked Gated Recurrent Unit and Random Forest

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Intelligent Automation & Soft Computing 2024年第2期39卷 233-254页

作者： Chao-Lung Yang Atinkut Atinafu Yilma Bereket Haile Woldegiorgis hendrik Tampubolon Hendri Sutrisno Department of Industrial Management National Taiwan University of Science and TechnologyTaipeiTaiwanChina Faculty of Mechanical and Industrial Engineering Bahir Dar Institute of Technology(BiT)Bahir DarUniversityBahir Dar6000Ethiopia Department of Computer Science and Information Engineering National Taiwan University of Science and TechnologyTaipeiTaiwanChina Department of Information System Faculty of Engineering and Computer ScienceKridaWacana Christian UniversityJakartaIndonesia Department of Information Management National Dong Hwa UniversityHualienTaiwanChina

This study proposed a new real-time manufacturing process monitoring method to monitor and detect process shifts in manufacturing *** real-time production process monitoring is critical in today’s smart *** more robust the monitoring model,the more reliable a process is to be under *** the past,many researchers have developed real-time monitoring methods to detect process shifts ***,thesemethods have limitations in detecting process shifts as quickly as possible and handling various data volumes and *** this paper,a robust monitoring model combining Gated Recurrent Unit(GRU)and Random Forest(RF)with Real-Time Contrast(RTC)called GRU-RF-RTC was proposed to detect process shifts *** effectiveness of the proposed GRU-RF-RTC model is first evaluated using multivariate normal and nonnormal distribution ***,to prove the applicability of the proposed model in a realmanufacturing setting,the model was evaluated using real-world normal and non-normal *** results demonstrate that the proposed GRU-RF-RTC outperforms other methods in detecting process shifts quickly with the lowest average out-of-control run length(ARL1)in all synthesis and real-world problems under normal and non-normal *** experiment results on real-world problems highlight the significance of the proposed GRU-RF-RTC model in modern manufacturing process monitoring *** result reveals that the proposed method improves the shift detection capability by 42.14%in normal and 43.64%in gamma distribution problems.

关键词： Smart manufacturing process monitoring quality control gated recurrent unit neural network random forest

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Unraveling the routes to distant metastases in colorectal cancer:Tumor deposits and lymph node metastases as the gateway

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Cancer Communications 2024年第10期44卷 1209-1213页

作者： Nelleke Pietronella Maria Brouwer Ayse Selcen Oguz Erdogan Shannon van Vliet Natasja Rutgers Nikki Knijn Gesina van Lijnschoten Jessica Juliana Tan Johannes hendrik Willem de Wilt Niek Hugen Gina Brown Femke Simmer Iris Dionne Nagtegaal Department of Pathology Radboud University Medical CenterNijmegenGelderlandThe Netherlands Department of Pathology PathologyDNAArnhemGelderlandThe Netherlands Department of Pathology Eurofins/Laboratoria voor Pathologie en Medische Microbiologie NederlandEindhovenNoord-BrabantThe Netherlands GI Cancer Imaging Research Unit The Royal Marsden HospitalSuttonLondonUnited Kingdom Department of Surgery Radboud University Medical CenterNijmegenGelderlandThe Netherlands Department of Surgery Netherlands Cancer InstituteAmsterdamNoord-HollandThe Netherlands Department of Surgery Rijnstate HospitalArnhemGelderlandThe Netherlands Imperial College London Hammersmith Campus LondonLondonUnited Kingdom

Currently,lymph node metastases(LNM)are seen as the gateway to distant metastases in CRC and play a crucial role in the Tumor Node Metastasis(TNM)staging system[1,2].Tumor deposits(TD)have been identified as another histological feature with a strong prognostic impact but are currently only deemed clinically relevant in the absence of LNM[2,3].TD are clusters of tumor cells in the fat surrounding the bowel and are often associated with nerves,vessels and lymphatic tissue,giving the cancer cells access to multiple routes of spread[4].

关键词： metastases cancer gateway

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Numerical and experimental investigation of sloshing under large amplitude roll excitation

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Journal of Hydrodynamics 2021年第4期33卷 787-803页

作者： Ronja Hoch Frank-hendrik Wurm Institute of Turbomachinery University of RostockRostockGermany

To enable a virtual design and optimization process of partially filled coolant tanks a reliable numerical approach is needed to predict the liquid and gas two phase flow inside the *** this study numerical results are validated by experimental data to examine the suitability of the method for the tank design *** liquid motion inside the tanks can be described as sloshing with high amplitude,off-resonant roll excitation and was examined using a homogeneous multiphase model and VOF interface capturing approach as well as an experimental setup including piezoelectric pressure sensors and qualitative observation of the free *** effect of two vertical baffles on the maximum pressure and the position of phase interface was *** comparison between the computational and experimental results reveals that the numerical model tends to under predict the experimental peak pressures but resolves the liquid surface in close agreement with the experiments.

关键词： Multiphase flows sloshing unsteady Reynolds averaged Navier-Stokes(URANS)

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Role of mucosal dendritic cells in inflammatory bowel disease

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World Journal of Gastroenterology 2008年第33期14卷 5138-5148页

作者： Jan hendrik Niess Department of Internal Medicine I Ulm UniversityUlm 89031 Germany

The gastrointestinal innate and adaptive immune system continuously faces the challenge of potent stimuli from the commensal microflora and food constituents. These local immune responses require a tight control, the outcome of which is in most cases the induction of tolerance. Local T cell immunity is an important compartment of the specif ic intestinal immune system. T cell reactivity is programmed during the initial stage of its activation by professional presenting cells. Mucosal dendritic cells (DCs) are assumed to play key roles in regulating immune responses in the antigen-rich gastrointestinal environment. Mucosal DCs are a heterogeneous population that can either initiate (innate and adaptive) immune responses, or control intestinal inflammation and maintain tolerance. Defects in this regulation are supposed to lead to the two major forms of inflammatory bowel disease (IBD), Crohn's disease (CD) and ulcerative colitis (UC). This review will discuss the emerging role of mucosal DCs in regulating intestinal inflammation and immune responses.

关键词： Dendritic cells Commensal Inflammatory bowel disease Mucosal immunity Host defence

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Realising Data-Centric Scientific Workflows with Provenance-Capturing on Data Lakes

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Data Intelligence 2022年第2期4卷 426-438页

作者： hendrik Noltet Philipp Wieder Gesellschaft fur wissenschaftliche Datenverarbeitung mbH Gottingen Gottingen Gottingen 37077Germany

Since their introduction by James Dixon in 2010,data lakes get more and more attention,driven by the promise of high reusability of the stored data due to the schema-on-read *** on this idea,several additional requirements were discussed in literature to improve the general usability of the concept,like a central metadata catalog including all provenance information,an overarching data governance,or the integration with(high-performance)processing *** the necessity for a logical and a physical organisation of data lakes in order to meet those requirements is widely recognized,no concrete guidelines are yet *** most common architecture implementing this conceptual organisation is the zone architecture,where data is assigned to a certain zone depending on the degree of *** paper discusses how FAIR Digital Objects can be used in a novel approach to organize a data lake based on data types instead of zones,how they can be used to abstract the physical implementation,and how they empower generic and portable processing capabilities based on a provenance-based approach.

关键词： Data lake Provenance Workflows FAIRDigital Objects CWFR

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Accurate simulation of surfaces and interfaces of ten FCC metals and steel using Lennard–Jones potentials

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npj Computational Materials 2021年第1期7卷 205-219页

作者： Krishan Kanhaiya Seonghan Kim Wonpil Im hendrik Heinz Department of Chemical and Biological Engineering University of Colorado at BoulderBoulderCO 80301USA Departments of Biological Sciences Chemistryand BioengineeringLehigh UniversityBethlehemPA 18015USA

The earlier integration of validated Lennard–Jones(LJ)potentials for 8 fcc metals into materials and biomolecular force fields has advanced multiple research fields,for example,metal–electrolyte interfaces,recognition of biomolecules,colloidal assembly of metal nanostructures,alloys,and *** we introduce 12-6 and 9-6 LJ parameters for classical all-atom simulations of 10 further fcc metals(Ac,Ca(α),Ce(γ),Es(β),Fe(γ),Ir,Rh,Sr(α),Th(α),Yb(β))and stainless *** parameters reproduce lattice constants,surface energies,water interfacial energies,and interactions with(bio)organic molecules in 0.1 to 5%agreement with experiment,as well as qualitative mechanical properties under standard *** are reduced up to a factor of one hundred in comparison to earlier Lennard–Jones parameters,embedded atom models,and density functional *** also explain a quantitative correlation between atomization energies from experiments and surface energies that supports parameter *** models are computationally very efficient and applicable to an exponential space of *** with a wide range of force fields such as the Interface force field(IFF),AMBER,CHARMM,COMPASS,CVFF,DREIDING,OPLS-AA,and PCFF enables reliable simulations of nanostructures up to millions of atoms and microsecond time ***-friendly model building and input generation are available in the CHARMM-GUI Nanomaterial *** a limitation,deviations in mechanical properties vary and are comparable to DFT *** discuss the incorporation of reactivity and features of the electronic structure to expand the range of applications and further increase the accuracy.

关键词： steel metals qualitative

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Rationally designed treatment for metastatic colorectal cancer:Current drug development strategies

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World Journal of Gastroenterology 2014年第30期20卷 10288-10295页

作者： Pavlina Spiliopoulou hendrik-Tobias Arkenau Drug Development Unit Sarah Cannon Research Institute United KingdomLondon W1G 6ADUnited Kingdom UCL Cancer Institute Medical OncologyUniversity College LondonLondon WC1E 6BTUnited Kingdom

The therapeutic landscape of metastatic colorectal cancer(mCRC)has changed substantially with the emergence of new molecularly targeted agents(MTA)usedas single agents or alongside standard *** use of these MTAs extended the overall survival ofpatients with mCRC to a level that current chemotherapeutics alone could not *** addition,improvement in surgical techniques and ablation modalities offer cure to a limited subset of patients with mCRC andMTAs have been found to have a significant role heretoo,as they aid ***,for the majority of patients,mCRC remains an invariably incurabledisease necessitating continued courses of combinedtreatment *** the course of these treatments,either cytotoxic or biological,cancer cells maintain their ability to acquire mitogenic mutations whichrender them resistant to *** challengesremain to identify appropriate subsets of patients whowill most likely benefit from these new MTAs and effectively select these based on validated ***,better knowledge of the biology of colorectal cancer and the mechanisms via which it bypasses blockade of known signalling pathways will help us design better and more rational sequencing of these treatments,so that we can maximise the survivorship of mCRC *** review outlines treatment strategies for known molecular alterations with new MTAs and highlights some promising strategies.

关键词： Colorectal cancer Molecularly targeted therapies Drug development

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