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Numerical Determination of the Circumferential Residual Stress of Porcine Aorta by Pulling-Back Method

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Acta Mechanica Solida Sinica 2021年第3期34卷 346-355页

作者： heming chen Wanjie Wang Qiang chen Zhiyong Li School of Biological Science and Medical Engineering Southeast UniversityNanjing 210096China School of Mechanical Medical and Process EngineeringQueensland University of TechnologyBrisbaneQLD 4001Australia

Residual stress is very important for the study of cardiovascular-relevant issues,such as assessing the vulnerability of atherosclerosis and aneurysm.In this paper,the circumferential residual stress of porcine aorta was characterized by combining ex vivo experiments with numerical studies.In the experiments,porcine aortic rings were prepared and cut open,and the cross sections of the opened aortic rings were extracted to construct finite element models.The 5-parameter Mooney-Rivlin model was chosen to describe the tensile mechanical behavior of the aorta.In numerical studies,based on the finite element models and hyperelastic material model,a pulling-back displacement was applied to reclose the models of the opened aortic rings,and the equivalent circumferential residual stress to the pre-opened aorta was analyzed.The results showed that the circumferential residual stress of the aorta generally decreased from the proximal to the distal ends,and the residual stresses of the aortic rings close to the distal end did not show a great difference.This work provides an improved understanding of the residual stress distribution in aorta and may be used as a more realistic initial condition for future stress analysis of the arterial tissue.

关键词： Aorta Circumferential residual stress Opening angle Finite element model

Ultralow cross talk arrayed waveguide grating integrated with tunable microring filter array

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Chinese Optics Letters 2024年第3期22卷 50-54页

作者：胡鹤鸣刘世平李天文范永杰陈华方青 College of Science Kunming University of Science and TechnologyKunming 650093China College of Electronic Science and Engineering Jilin UniversityJilin 130012China

The silicon-based arrayed waveguide grating(AWG)is widely used due to its compact footprint and its compatibility with the mature CMOS process.However,except for AWGs with ridged waveguides of a few micrometers of cross section,any small process error will cause a large phase deviation in other AWGs,resulting in an increasing cross talk.In this paper,an ultralow cross talk AWG via a tunable microring resonator(MRR)filter is demonstrated on the SOI platform.The measured insertion loss and minimum adjacent cross talk of the designed AWG are approximately 3.2 and-45.1 d B,respectively.Compared with conventional AWG,its cross talk is greatly reduced.

关键词： SOI platform arrayed waveguide grating cross talk microring filter array thermo-optic effect

A novel conceptual design of a biomimetic oral implant and its biomechanical effect on the repairment of a large mandibular defect

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Medicine in Novel Technology and Devices 2022年第3期15卷 72-82页

作者： Yongheng Li Yuanbin Hu heming chen Xiangfeng Meng Du chen Hongcheng Gu Qiang chen Zhongde Mu Zhiyong Li School of Biological Science&Medical Engineering Southeast UniversityNanjing210096China Zhongda Hospital The Affiliated Hospital of Southeast UniversityNanjing210009China Department of Prothodontics Nanjing Stomatological HospitalMedical School of Nanjing UniversityNanjing210018China Jiangsu Institute of Cancer Research Jiangsu Cancer HospitalNanjing Medical University Affiliated Cancer HospitalNanjing210002China School of Mechanical Medical and Process EngineeringQueensland University of Technology(QUT)BrisbaneQLD4001Australia

This study aimed to propose a novel biomimetic design strategy of an oral implant and to numerically examine its biomechanical effect according to clinical interests.The designed implant conceptually mimicked the morphology and elastic modulus of the mandibular bone.Basing on a CT-image-based patient-specific reconstruction of the tumor-excised mandible,the biomechanical effects of the implants with three materials(PEEK/n-HA/CF,PEEK/HA and Ti6Al4V),two surgical conditions(removed and retained muscles),and two postoperative stages(early and late)were fully investigated by a static finite element analysis.Moreover,according to clinical interests(e.***.failure and stability of the implant and rivets),maximum von Mises stresses and strains of the implant and rivets,maximum implant-bone gap in the early postoperative stage,and maximum von Mises stress of the mandible were mainly analyzed.The results showed that the implant composed of Ti6Al4V material was suitable for the current design strategy with respect to the other two PEEK-based materials.Although the implants in the muscle-retained surgical condition had relative greater indices compared to the muscle-removed surgical condition,the index difference between the two conditions was slight.The biomechanical indices indicating the failure and loosening risks of implant and rivets were much reduced in the late postoperative stage with respect to the early postoperative stage due to the osteointegration at the implant-bone interface.Generally,the proposed novel design strategy could be useful to guide the design of the oral implant addressing different implant materials and surgical conditions,and further made proper suggestion to clinicians and patients.

关键词： Large mandibular defect Biomimetic oral implant Biomechanical effect Failure and instability Finite element method

蝴蝶兰属与钻喙兰属通用SSR引物的开发与应用

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园艺学报 2024年第5期51卷 1056-1068页

作者：肖文芳李佐陈和明吕复兵广东省农业科学院环境园艺研究所广东省园林花卉种质创新综合利用重点实验室广州510640

利用蝴蝶兰属28个种的38份原生种资源和钻喙兰属3个种的9份原生种资源的简化基因组测序数据,开发筛选出多态性高、通用性强的19对蝴蝶兰属内种间通用、12对钻喙兰属内种间通用和12对两属间通用的SSR引物。采用荧光标记毛细管电泳进行等... 详细信息

利用蝴蝶兰属28个种的38份原生种资源和钻喙兰属3个种的9份原生种资源的简化基因组测序数据,开发筛选出多态性高、通用性强的19对蝴蝶兰属内种间通用、12对钻喙兰属内种间通用和12对两属间通用的SSR引物。采用荧光标记毛细管电泳进行等位变异检测,12对属间通用引物在两个属的47份种质中共检测到134个等位基因,每对引物扩增出等位基因6~17个,平均观测等位基因数(N_(a))为11.17,平均有效等位基因数(N_(e))为6.36,期望杂合度(H_(e))为0.66~0.88,观测杂合度(H_(o))为0.07~0.38。所有引物位点均呈高多态性,Shannon指数介于1.30~2.43,均值为1.88,说明引物的多态性极高,适用于蝴蝶兰属和钻喙兰属种质资源的鉴定。47份种质资源聚类结果和群体结构分析能较明确地揭示蝴蝶兰属和钻喙兰属种质的亲缘关系,与植物学分类结果基本一致。在蝴蝶兰‘Red Rose’与钻喙兰的跨属杂交F1代群体检测中,有23对通用引物具多态性,扩增出75个多态性条带,杂种之间的遗传相似系数介于0.58~1.00,母本与属间杂种的平均遗传相似性系数(0.62)高于父本(0.54),表明该跨属杂交F1代偏母系遗传,与表型观测结果吻合。

关键词：蝴蝶兰属钻喙兰属跨属远缘杂交 SSR通用引物

Analysis of band gap of non-bravais lattice photonic crystal fiber

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Frontiers of Electrical and Electronic Engineering in China 2009年第2期4卷 239-242页

作者： Yichao MA heming chen College of Optoelectronic Engineering and Institute of Optical Communications Nanjing University of Posts and TelecommunicationsNanjing 210003China

This article designs a novel type of non-bravais lattice photonic crystal fiber.To form the nesting complexperiod with positive and negative refractive index materials respectively,a cylinder with the same radius and negative refractive index is introduced into the center of each lattice unit cell in the traditional square lattice air-holes photonic crystal fiber.The photonic band-gap of the photonic crystal fiber is calculated numerically by the plane wave expansion method.The result shows that compared with the traditional square photonic band-gap fiber(PBGF),when R=Λis 0.35,the refractive index of the substrate,airhole,and medium-column are 1.30,1.0,and–1:0,respectively.This new PBGF can transmit signal by the photonic band-gap effect.When the lattice constantΛvaries from 1:5μm to 3:0μm,the range of the wavelength ranges from 880 nm to 2300 nm.

关键词： photonic crystal fiber negative refractive index non-bravais lattice photonic band-gap

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1型糖尿病的免疫治疗进展

中华糖尿病杂志 2024年第1期16卷 101-105页

作者：朱蒙蒙郭鹤鸣李思诚方晨苏州大学第二附属医院内分泌科苏州215004

1型糖尿病(T1DM)是由T细胞介导以破坏胰腺β细胞为特征的慢性自身免疫性疾病。目前T1DM的治疗手段有限,常规方法包括注射胰岛素和胰岛/胰腺移植,但均没有从根本上解决胰岛功能减退的问题。人们期望基于病因治疗——免疫治疗以阻止或延... 详细信息

1型糖尿病(T1DM)是由T细胞介导以破坏胰腺β细胞为特征的慢性自身免疫性疾病。目前T1DM的治疗手段有限,常规方法包括注射胰岛素和胰岛/胰腺移植,但均没有从根本上解决胰岛功能减退的问题。人们期望基于病因治疗——免疫治疗以阻止或延缓β细胞的损伤,保护残存的胰岛功能以达到预防甚至逆转T1DM的目的,并且多年来包括针对T细胞、B细胞、炎性细胞因子以及微生物起源的免疫治疗开始取得成效。该文对近年来T1DM免疫治疗的进展进行总结和展望。

关键词：糖尿病 1型 T细胞功能 B细胞功能免疫治疗

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聚氨酯/黑种草子伤口敷料的制备与性能表征

功能高分子学报 2024年第2期37卷 148-156页

作者：陈鹤鸣胡娇康花于萍程璐王颖新疆大学纺织与服装学院乌鲁木齐830046

利用静电纺丝技术制备了负载不同浓度黑种草子提取物(NSS)的聚氨酯(PU)纳米纤维膜(PU/NSS)。对该纳米纤维膜的力学性能、亲水性、溶胀性、透气性、抗氧化性、抗菌性以及细胞毒性进行了表征,探讨了其在伤口敷料领域的应用潜力。结果表明:... 详细信息

利用静电纺丝技术制备了负载不同浓度黑种草子提取物(NSS)的聚氨酯(PU)纳米纤维膜(PU/NSS)。对该纳米纤维膜的力学性能、亲水性、溶胀性、透气性、抗氧化性、抗菌性以及细胞毒性进行了表征,探讨了其在伤口敷料领域的应用潜力。结果表明:PU/NSS纳米纤维膜的纤维直径随着NSS含量的增加而增大,且NSS的加入改善了PU纳米纤维膜的亲水性。另外,NSS中的活性成分使PU/NSS纳米纤维膜表现出优异的抗氧化性和抗菌性,可以有效避免伤口感染。细胞毒性试验结果证明PU/NSS纳米纤维膜具有良好的生物相容性。

关键词：静电纺丝黑种草子聚氨酯伤口敷料细胞毒性

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蝴蝶兰新品种‘娇红’

园艺学报 2024年第3期51卷 701-702页

作者：吕复兵陈和明肖文芳李佐广东省农业科学院环境园艺研究所广东省园林花卉种质创新综合利用重点实验室广州510640

‘娇红’是以‘红冠’为母本,‘红霞’为父本,通过人工授粉杂交选育出来的小花型紫花蝴蝶兰新品种。植株株幅28.4 cm,叶长16.8 cm,叶宽6.4 cm,单枝花朵数8.2朵,花枝长45.6 cm,花径7.0 cm;花形圆整,花色紫红,萼片和花瓣的RHS比色卡值为5... 详细信息

‘娇红’是以‘红冠’为母本,‘红霞’为父本,通过人工授粉杂交选育出来的小花型紫花蝴蝶兰新品种。植株株幅28.4 cm,叶长16.8 cm,叶宽6.4 cm,单枝花朵数8.2朵,花枝长45.6 cm,花径7.0 cm;花形圆整,花色紫红,萼片和花瓣的RHS比色卡值为57B,唇瓣RHS比色卡值为57A。花期长达2~3个月。

关键词：蝴蝶兰紫花小花型品种

PS@SiO_(2)微球的合成及其三维光子晶体的光学性能

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功能高分子学报 2024年第1期37卷 32-40页

作者：胡娇李帅康花陈鹤鸣王译泽王颖新疆大学纺织与服装学院乌鲁木齐830017

以乙烯基三乙氧基硅烷为硅源,通过其在碱性条件下的水解缩聚,在聚苯乙烯(PS)微球表面包覆乙烯基修饰的二氧化硅(Vi-SiO_(2))壳层制备PS@SiO_(2)微球,并通过刮涂法进一步制得PS@SiO_(2)三维光子晶体。对比了PS微球在包覆Vi-SiO_(2)前后... 详细信息

以乙烯基三乙氧基硅烷为硅源,通过其在碱性条件下的水解缩聚,在聚苯乙烯(PS)微球表面包覆乙烯基修饰的二氧化硅(Vi-SiO_(2))壳层制备PS@SiO_(2)微球,并通过刮涂法进一步制得PS@SiO_(2)三维光子晶体。对比了PS微球在包覆Vi-SiO_(2)前后的微观形貌、粒径和化学组成的差异,分析了PS@SiO_(2)光子晶体的形貌和光学性能。结果表明:Vi-SiO_(2)在PS微球表面形成了均匀且光滑的外壳,并且Vi-SiO_(2)的包覆对PS微球的单分散性和球形度无明显影响。由4种不同粒径的PS@SiO_(2)微球自组装的三维光子晶体都具有规则的面心立方结构,其结构色随PS@SiO_(2)微球粒径的增大发生红移,并且都具有虹彩效应。

关键词：光子晶体结构色核壳微球光学性能二氧化硅