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Cancer Communications 2022年第7期42卷 673-676页

作者： Johannes Diers Laura Acar Johanna C.Wagner Philip Baum Mohammed Hankir Sven Flemming Carolin Kastner Christoph-Thomas Germer helmut L’hoest Ursula Marschall Johan Friso Lock Armin Wiegering Department of General VisceralTransplantationVascular and Pediatric SurgeryUniversity HospitalUniversity of WuerzburgWuerzburg 97080Germany Department Medizin und Versorgungsforschung Institut fuer GesundheitssystemforschungBarmerWuppertal 42275Germany Department of Biochemistry and Molecular Biology University ofWuerzburgWuerzburg 97074Germany Comprehensive Cancer Centre Mainfranken University of Wuerzburg Medical CentreWuerzburg 97080Germany

Dear Editor,The coronavirus disease of 2019(COVID-19)pandemic has necessitated that semi-urgent and elective medical cases,including cancer screenings,are postponed in hospitals worldwide to accommodate the increasing number of patients with severe COVID-19 symptoms[1-4].Consequently,several reports from the first COVID-19 wave in spring 2020 showed a significant decrease in new cancer diagnoses as well as cancer therapy and screenings[5,6].

关键词： diagnosis cancer Cancer

Improved allometric equations for tree aboveground biomass estimation in tropical dipterocarp forests of Kalimantan,Indonesia

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Forest Ecosystems 2017年第2期4卷 83-92页

作者： Solichin Manuri Cris Brack Fatmi Noor'an Teddy Rusolono Shema Mukti Anggraini helmut Dotzauer Indra Kumara Fenner School of Environment and Society The Australian NationalUniversityLinnaeus Way Building 141Canberra ACT2601Australia Dipterocarps Research Center Forest Research Development and Innovation AgencyMinistry of Environment and ForestryJl.AW SyahraniSamarindaEast KalimantanIndonesia Faculty of Forestry Bogor Agricultural UniversityJl Raya DarmagaKampus IPBBogor 16680Indonesia Forests and Climate Change Program Deutsche Gesellschafc fur Internationale Zusammenarbeit(FORCLIME-GIZ)Manggala Wanabakti BuildingBlock VII6th floorJakartaIndonesia Biodiversity and Climate Change Program Deutsche Gesellschafr fur Internationale Zusammenarbeit(BIOCLIME-GIZ)Manggala Wanabakti BuildingBlock VIL 6th floorJakartaIndonesia District Forestry and Plantation Service Jl.Antasarl No 4 Putussibaa Kapuas Hulu 78711West KalimantanIndonesia

Background： Currently, the common and feasible way to estimate the most accurate forest biomass requires ground measurements and allometric *** studies have been conducted on allometric equations development for estimating tree aboveground biomass（AGB） of tropical dipterocarp forests（TDFs） in Kalimantan（Indonesian Borneo）.However, before the use of existing equations, a validation for the selection of the best allometric equation is required to assess the model bias and *** study aims at evaluating the validity of local and pantropical equations; developing new allometric equations for estimating tree AGB in TDFs of Kalimantan; and validating the new equations using independent ***： We used 108 tree samples from destructive sampling to develop the allometric equations, with maximum tree diameter of 175 cm and another 109 samples from previous studies for validating our *** performed ordinary least squares linear regression to explore the relationship between the AGB and the predictor variables in the natural logarithmic ***： This study found that most of the existing local equations tended to be biased and imprecise, with mean relative error and mean absolute relative error more than 0.1 and 0.3, *** developed new allometric equations for tree AGB estimation in the TDFs of *** a validation using an independent dataset,we found that our equations were reliable in estimating tree AGB in *** pantropical equation, which includes tree diameter, wood density and total height as predictor variables performed only slightly worse than our new ***： Our equations improve the precision and reduce the bias of AGB estimates of *** models developed from small samples tend to systematically bias.A validation of existing AGB models is essential before the use of the models.

关键词： Allometric equation Local and pantropical models AGB Model validation Destructive sampling Tropical dipterocarp forest

Precise Control of Highly Ordered Arrays of Nested Semiconductor/Metal Nanotubes

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Nano Research 2011年第2期4卷 164-170页

作者： Diefeng Gu helmut Baumgart Kandabara Tapily Pragya Shrestha Gon Namkoong Xianyu Ao Frank Müller Department of Electrical Engineering Old Dominion University Norfolk Virginia 23529 USA The Applied Research Center Newport News Virginia 23606 USA Max Planck Institute of Microstructure Physics Halle Germany

与原子层免职(ALD ) 一起的平版画地定义的多微孔的模板技术启用复杂新奇嵌套的 nanotube 结构的显著控制。物理进程参数的到目前为止三维的控制充分没与高精确分辨率被认识到，并且要求优化以便完成大量潜在的应用程序。而且，与半导... 详细信息

与原子层免职(ALD ) 一起的平版画地定义的多微孔的模板技术启用复杂新奇嵌套的 nanotube 结构的显著控制。物理进程参数的到目前为止三维的控制充分没与高精确分辨率被认识到，并且要求优化以便完成大量潜在的应用程序。而且，与半导体的层和金属轮流出现的合成绝缘氧化物层的联合能提供新奇应用的各种各样的类型并且最后提供多功能的 nanoscale 设备的唯一、先进的层次。半导体的 TiO2 nanotubes 在光电的设备有潜在的应用。nanostructured 的联合有嵌套的金属 nanotubes 的半导体的材料有潜力生产新奇多功能的垂直地命令的三维的 nanodevices。由 ALD 的铂生长被探索了，盖住薄电影成核过程和高方面比率 nanotube 结构的合成的起始的阶段。进有各种各样的毛孔尺寸和方面比率的多孔的模板的磅的穿入深度被调查了。在系列的几多围的嵌套的 TiO2 磅 nanotubes 成功地用多微孔的 Si 模板被制作了。这些创新嵌套的 nanostructures 有潜力在光电、察觉到的技术生产新奇多功能的垂直地命令的三维的 nanodevices。

关键词：碳纳米管阵列精确控制半导体层嵌套金属 TiO2纳米管纳米半导体材料纳米管结构

Monte Carlo Hamiltonian: Linear Potentials

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Communications in Theoretical Physics 2002年第5期38卷 561-565页

作者： LUO Xiang-Qian LIU Jin-Jiang HUANG Chun-Qing JIANG Jun-Qin helmut KROGER Department of Physics Zhongshan University Guangzhou 510275 China Department of Physics Zhongshan University Guangzhou 510275 China Department of Physics Zhongshan University Guangzhou 510275 China Department of Physics Zhongshan University Guangzhou 510275 China 2Département de Physique Université Laval Québec Québec G1K 7P4 Canada

We further study the validity of the Monte Carlo Hamiltonian method. The advantage of the method,in comparison with the standard Monte Carlo Lagrangian approach, is its capability to study the excited states. Weconsider two quantum mechanical models: a symmetric one V(x) = |x|/2; and an asymmetric one V(x) = ∞, forx ＜ 0 and V(x) = x, for x ≥ 0. The results for the spectrum, wave functions and thermodynamical observables are inagreement with the analytical or Runge-Kutta calculations.

关键词： Monte Carlo method, quantum mechanics, computational physics

FIRST AMMONITE AND INOCERAMID DATA FROM THE UPPER CRETACEOUS OF THE TINGRI SECTION IN SE-TIBET:BIOSTRATIGRAPHICAL AND PALAEOENVIRONMENTAL IMPLICATIONS

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地学前缘 2005年第2期12卷 105-112页

作者： Jens LEHMANN Ines WENDLER Jens WENDLER helmut WILLEMS Xiumian HU Geosciences Collection Department of GeosciencesUniversity of BremenKlagenfurter StrasseD-28359 BremenGermany Historical Geology and Palaeontology Department of GeosciencesUniversity of BremenKlagenfurter StrasseD-28359 BremenGermany Department of Earth Sciences Nanjing UniversityNanjing 210093China

A section in the Zhepure Mountains near Old Tingri in SE-Tibet,ranging from the Upper Albian to Paleogene,was described in detail by Willems et al.(1996).These authors worked on the litho-and microfacies and set up the biostratigraphical framework by planktonic *** et al.(1996)established their section as a standard for southern Tibet and compared it to the Gamba *** the 2004 Tibet-expedition of Chengdu University of Technology in China,in co-operation with Bremen and Kiel universities in Germany,the locality was revisited for the purpose of collecting invertebrate *** field-work included only the Upper Cretaceous part of the Tingri section and its invertebrate faunal *** today almost no ammonite and inoceramid data existed for this *** is true for most Cretaceous sections in Tibet,although the Upper Cretaceous succession was interpreted as shelf *** in other parts of the world contains rich faunas of these macrofossil *** newly discovered continuous record of rare ammonites and inoceramids is probably limited since the preservation in the wacke-and packstones is *** addition,sampling conditions were unfavorable and the environmental conditions disadvantageous for most groups of invertebrates,as possibly indicated by larger amounts of small bivalve debris(filaments)in the upper part of the Gamba *** the collected fauna is sparse and poorly preserved,the following biostratigraphical data can be added to the hitherto described microfauna:Calycoceras?from the Upper Gamba Group is Late Cenomanian in age and is accompanied by indeterminable juvenile *** follows a record of the ammonite Forresteria sp.,indicating that this level in the upper part of the Gamba Group belongs to the Lower *** supports the finding of Inoceramus(Cremnoceramus)waltersdorfensis?hannovrensis?from the same ***?is an individual ammonite finding from the

关键词： ammonite inoceramid Upper Cretaceous biostratigraphy palaeoenvironment Tingri Maastrichtian Tibet

A Fundamentally Irreversible World as an Opportunity towards a Consistent Understanding of Quantum and Cosmological Contexts

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Journal of Modern Physics 2016年第12期7卷 1455-1482页

作者： helmut Tributsch Bio-Mimetics in Energy Systems Program Carinthia University for Applied Sciences Villach Austria

In a preceding publication a fundamentally oriented and irreversible world was shown to be derivable from the important principle of least action. A consequence of such a paradigm change is avoidance of paradoxes within a “dynamic” quantum physics. This becomes essentially possible because fundamental irreversibility allows consideration of the “entropy” concept in elementary processes. For this reason, and for a compensation of entropy in the spread out energy of the wave, the duality of particle and wave has to be mediated via an information self-image of matter. In this publication considerations are extended to irreversible thermodynamics, to gravitation and cosmology with its dependence on quantum interpretations. The information self-image of matter around particles could be identified with gravitation. Because information can also impose an always constant light velocity there is no need any more to attribute such a property to empty space, as done in relativity theory. In addition, the possibility is recognized to consider entropy generation by expanding photon fields in the universe. Via a continuous activation of information on matter photons can generate entropy and release small energy packages without interacting with matter. This facilitates a new interpretation of galactic redshift, emphasizes an information link between quantum- and cosmological phenomena, and evidences an information-triggered origin of the universe. Self-organized processes approach maximum entropy production within their constraints. In a far from equilibrium world also information, with its energy content, can self-organize to a higher hierarchy of computation. It is here identified with consciousness. This appears to explain evolution of spirit and intelligence on a materialistic basis. Also gravitation, here identified as information on matter, could, under special conditions, self-organize to act as a super-gravitation, offering an alternative to dark matter. Time is not an il

关键词： Fundamental Irreversibility Gravitation as Information Redshift as Entropy Phenomenon Constancy of Light Velocity Time Information Driven Universe

On the Fundamental Meaning of the Principle of Least Action and Consequences for a “Dynamic” Quantum Physics

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Journal of Modern Physics 2016年第4期7卷 365-374页

作者： helmut Tributsch Bio-Mimetics in Energy Systems Program Carinthia University for Applied Sciences Villach Austria

The principle of least action, which has so successfully been applied to diverse fields of physics looks back at three centuries of philosophical and mathematical discussions and controversies. They could not explain why nature is applying the principle and why scalar energy quantities succeed in describing dynamic motion. When the least action integral is subdivided into infinitesimal small sections each one has to maintain the ability to minimize. This however has the mathematical consequence that the Lagrange function at a given point of the trajectory, the dynamic, available energy generating motion, must itself have a fundamental property to minimize. Since a scalar quantity, a pure number, cannot do that, energy must fundamentally be dynamic and time oriented for a consistent understanding. It must have vectorial properties in aiming at a decrease of free energy per state (which would also allow derivation of the second law of thermodynamics). Present physics is ignoring that and applying variation calculus as a formal mathematical tool to impose a minimization of scalar assumed energy quantities for obtaining dynamic motion. When, however, the dynamic property of energy is taken seriously it is fundamental and has also to be applied to quantum processes. A consequence is that particle and wave are not equivalent, but the wave (distributed energy) follows from the first (concentrated energy). Information, provided from the beginning, an information self-image of matter, is additionally needed to recreate the particle from the wave, shaping a “dynamic” particle-wave duality. It is shown that this new concept of a “dynamic” quantum state rationally explains quantization, the double slit experiment and quantum correlation, which has not been possible before. Some more general considerations on the link between quantum processes, gravitation and cosmological phenomena are also advanced.

关键词： Least Action Calculus of Variations Dynamic Energy Quantum Paradoxes Quantum Correlation

Pancreatic cancer–Staging laparoscopy

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The Chinese-German Journal of Clinical Oncology 2007年第2期6卷 129-132页

作者： Wenhao Tang Junsheng Li Weidong Chen helmut Friess Department of General Surgery Southeast University Zhongda Hospital Nanjing 210009 China Department of General Surgery University of Heideiberg Im Neuenheimer Feld 110 69120 Heidelberg Germany

Objective: Accurate staging of patients with pancreatic cancer is crucial to clarify whether meaningful resection is indeed possible. Staging laparoscopy has been suggested as a tool for staging which may spare up to two-fifth of these patients from undergoing nontherapeutic laparotomy. A controversy exists, however, as to whether the procedure should be used routinely or selectively in these patients with no evidence of metastasis on noninvasive staging. This review aims to evaluate the available literature critically, identify its limitations and address the existing controversies. Methods: The current available English literature was reviewed on this topic. Results: A direct and conclusive comparison of the controversial literature is difficult because of inconsistent use of high-quality CT scans, different study designs and dissimilarity of judgment for non-resectability among patients staged by laparoscopy. However, recent studies reveal that not more than 14% of the patients benefit from diagnostic laparoscopy when a dual-contrast thin cut and 3-D digital reformatting CT scan has been performed previously. Conclusion: We conclude that routine use of diagnostic laparoscopy does not appear warranted in all patients with pancreatic cancer, especially for patients with early-staged pancreatic cancer or non-pancreatic periampullary cancers, because diagnostic laparoscopy is costly and ultrasonography is largely operator-dependent. Rather, selective use is appropriate, especially in patients with a large primary tumor, a tumor in the body or tail of the pancreas, equivocal findings of metastasis on CT, the presence of ascites, severe weight loss, hypoalbuminemia, and a markedly elevated CA 19–9.

关键词：胰腺癌分期腹腔镜检查诊断 CT

Time-Neutrality of Natural Laws Challenged: Time Is Not an Illusion but Ongoing Energy-Driven Information Loss

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Journal of Modern Physics 2021年第3期12卷 300-327页

作者： helmut Tributsch Institute for physical and theoretical Chemistry Free University Berlin Germany Helmholtz Centre Berlin for Materials and Energy Berlin Germany

It is shown that the time of entropy increase, here called action time, is caused by a dynamically understood energy. It drives time by decreasing its presence per state, that is by abandoning order, information, and creating entropy. This mechanism can be derived from basic principles via the Lagrange-Euler formalism, just considering the properties of really experienced, oriented time and thus abandoning the paradigm of time neutrality. It describes nature driven by a dynamically understood principle of least action, which is identified as manifestation of fundamental irreversibility in nature. This readily explains the second law of thermodynamics and also yields the entropy law for non-linear irreversible thermodynamics: maximum entropy production within the restraints of the system. Dynamic energy-driven time, action time, and time asymmetry is generated via the process of erasing information and liberating its energy irreversibly as heat. It is not an illusion but information-based reality. It is the loss of information to the past and different from clock-time, which is just an artificial scale, using information for tracking real time, action time. Energy-driven fundamental irreversibility of nature can better describe experienced reality and opens the way to understand and finally imitate the self-organizing creativity in nature. It also draws far reaching consequences for understanding quantum physics, gravitation and cosmology as well as biology. From the point of view of irreversibility, nature turns out to be more elegant, simpler and rationally understandable. For the first time, it can be explained in a few words what energy and nature basically represent and why it must have been information, which has started the universe.

关键词： Time-Invariance Energy Time Entropy Information Irreversibility Self-Organization Nature

Lotz:Bohmisches Glas 1880 bis 1940=洛茨的波西米亚玻璃艺术1880-1940/

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