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Evaluation of Biochemical, Hematological and Histological Parameters in Non Diabetic and Diabetic Wistar Rats Fed with Monosodium Glutamate

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Food and Nutrition Sciences 2013年第1期4卷 66-76页

作者： hellen D.B.Maluly Miguel A.Areas Primavera Borelli Felix G.R.Reyes Department of Food Science School of Food EngineeringUniversity of CampinasSao PauloBrazil Department of Structural and Functional Biology Institute of BiologyUniversity of CampinasSao PauloBrazil Faculty of Pharmaceutical Sciences University of Sao PauloSao PauloBrazil

The parenteral or oral administration of monosodium glutamate (MSG) has been reported to have a deleterious effect on the hypothalamic arcuate nucleus, which changes appetite control. This alteration in function may lead to obesity and disorders related to metabolic syndrome, such as alterations in carbohydrate metabolism (glucose and insulin resistance), dyslipidemia and cardiovascular disease. This study evaluates the induction of metabolic alterations due to subchronic consumption of diets containing MSG at levels of 1.0%, 2.5% and 5.0%. Initially the animals (newborn male Wistar rats) consumed the diets containing MSG for a period of 70 days. At the end of this period diabetes was induced by streptozotocin (STZ) and the rats maintained on the same diets for additional 21 days. The induction of diabetes is based on the susceptibility of diabetic animals to metabolic disorders. Methods capable of evaluating the entire metabolic profile of the diabetic condition were used, including biochemical tests and tests able to detect alterations in the organs usually affected by this disease. It was concluded that the consumption of diets containing up to 5.0% MSG did not change the studied parameters for both: diabetic or non-diabetic animals. The alterations observed in the diabetic animals mainly reflected metabolic changes caused by the disease and were not related to the administration of MSG.

关键词： MSG Glutamate Wistar Rat Diabetes

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如何看待中国当代艺术市场 005

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上海证券报

作者：杨琳 hellen

胡润百富近日在上海举办了一场“中国当代艺术思路引导者”颁奖典礼，邀请了2009胡润艺术榜5位上榜艺术家周春芽、尹朝阳、王沂东、李山和向京以及50多位业内藏家、专业人士和商界精英。本刊在现场特别采访了到场的十多位专业人士，包...

胡润百富近日在上海举办了一场“中国当代艺术思路引导者”颁奖典礼，邀请了2009胡润艺术榜5位上榜艺术家周春芽、尹朝阳、王沂东、李山和向京以及50多位业内藏家、专业人士和商界精英。本刊在现场特别采访了到场的十多位专业人士，包括艺术家、艺术机构经营者和管理者以及商界

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我在雪乡过大年杠杠的,贼过瘾!

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东北之窗 2019年第1期 44-45页

作者：赵燕文秀(图) hellen(图) 不详

一铺大炕,两张炕桌,来上个十个八个人凑在一起,那绝对是贼热闹。走在大街上,满街都是叫卖声和飘散四溢的香味。集市上人们比肩接踵,肩扛手提,道路两旁年货,生活用品琳琅满目,所有人脸上都洋溢着笑容和喜悦。小孩拉着大人讨要着心爱的糖... 详细信息

一铺大炕,两张炕桌,来上个十个八个人凑在一起,那绝对是贼热闹。走在大街上,满街都是叫卖声和飘散四溢的香味。集市上人们比肩接踵,肩扛手提,道路两旁年货,生活用品琳琅满目,所有人脸上都洋溢着笑容和喜悦。小孩拉着大人讨要着心爱的糖果和零食;热气腾腾的大锅里炖着各种卤煮;活鸡现杀当场拔毛;还有大活鱼,大旱烟大麻花,总之,就不让你的嘴闲着。没错,这就是东北农村最常见的过年场景。一进入腊月,这里的村镇便热闹了起来,年味儿越来越浓。

关键词：老少爷们儿零食活鸡满街旱烟雪乡杠杠东北

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Comparison between Elderly Persons of the Urban Community, According to the Indicative of Depression

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Open Journal of Nursing 2017年第2期7卷 158-168页

作者： Lilane Maria Alves Silva Sheron hellen da Silva Darlene Mara dos Santos Tavares Leiner Resende Rodrigues The Federal University of Triângulo Mineiro Uberaba MG Brazil

Objectives: To compare the sociodemographic and economic profile, functional capacity, number of self-referred morbidities and level of physical activity among the elderly with and without indicative of depression. Methods: Cross-sectional and analytical study, with 980 elderly persons (250 with and 730 without indicative of depression) residing in the city of Uberaba, in the State of Minas Gerais, Brazil, between August 2012 and May 2013. We used the BOMFAQ Questionnaire, GDS 15, Katz Index, Lawton and Brody Scale and IPAQ. For data analysis, descriptive statistics and the Chi-square test (p Results: In the comparison between the groups, there were significant differences regarding the female gender (p = 0.009), education (p = 0.008), individual income (p Conclusion: The comparison of the existence or not of depressive symptoms among the elderly enables a more effective planning of public policies aimed at health promotion and adequate treatment in cases of disease already present and the subsidization of preventive strategies, using data such as risk factors and associated factors and ways to research depression.

关键词： Depression Aged Motor Activity Activities of Daily Living

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Dietary Monosodium Glutamate Does Not Affect the Electrocardiographic Profiles of Diabetic and Nondiabetic Wistar Rats

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Food and Nutrition Sciences 2019年第6期10卷 613-625页

作者： Miguel Arcanjo Areas hellen Dea Barros Maluly Jean Franciesco Vettorazzi Everardo Magalhaes Carneiro Felix Guillermo Reyes Reyes Institute of Biology University of Campinas/UNICAMPCampinasBrazil School of Food Engineering University of Campinas/UNICAMPCampinasBrazil

Background and Aims: Some studies have recently indicated that dietary monosodium glutamate (MSG) is linked to obesity and the development of diabetes. Both diseases induce cardiovascular changes, such as increases in blood pressure and arrhythmias, including ventricular fibrillation, which may result in sudden death. Here, we aimed to investigate the effects of oral MSG administration on the electrical conduction and histological dysfunctions of the heart in control and diabetic Wistar rats. Methods and Results: Twenty-one-day-old Wistar rats were fed diets containing 0.0%, 1.0%, 2.5% or 5.0% MSG for 70 days. After this period, diabetes was induced with streptozotocin (STZ;50 mg/kg bw) in half the rats and after an additional 21 days period;the electrocardiographic parameters and heart histology were evaluated. Diabetic rats demonstrated a reduction in heart rate as well as an enlargement of the QRS complex and QT and QTc intervals. Nevertheless, those changes are typical of STZ-induced diabetes, mainly because of electrolyte disturbances. The presence of MSG in the diet did not change the parameters evaluated between the group that received MSG and the group that did not receive MSG. Moreover, no histological alterations in the heart were observed due to MSG ingestion. Conclusion: Based on this evidence, diets containing MSG did not interfere with cardiovascular changes due to diabetes;there were no differences in the electrocardiographic and histological characteristics of the hearts of rats treated with MSG.

关键词： Monosodium Glutamate Diabetes Cardiovascular Changes Streptozotocin

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Self monitoring of blood glucose and its association with glycaemic control and lipid levels in type 2 diabetic patients aged 40 - 75 in Trinidad and Tobago

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Journal of Diabetes Mellitus 2012年第3期2卷 294-300页

作者： B. Shivananda Nayak Khateija Gowrie Renelle Romano Carl Spencer Domonique Noel hellen Bissoon Ikageng Dipatene Nadia Mahabir Rissa Ragbir Shalane Xavier Department of Preclinical Sciences Faculty of Medical Sciences The University of the West Indies St. Augustine Trinidad and Tobago

This study was done to assess whether self monitoring of blood glucose is associated with better glycaemic control in type 2 diabetic Trinidadians. Data was collected from 146 type 2 diabetics via interviews and medical files. Variables extracted included fasting blood glucose, HbA1c and lipid profile. Recent users of the glucometer had better glycemic control compared with longstanding users (HbA1c: 8.4% ± 0.28% vs 9.4% ± 0.62%). Diabetics using a glucometer for >11 years had the highest cholesterol (234 ± 27mg/dL) while those using it 6 months to 5 yrs had the lowest values (206 ± 8 mg/dL). Using the glucometer occasionally or once a week had little impact on these indices. Usage of insulin preparation was positively correlated with HbA1c (r = 0.295;p = 0.001) while those relying on oral hypoglycaemic agents showed a negative correlation (r = -0.265). Further, those who took their medication as prescribed had a lower HbA1c than those who took their medication occasionally. Ironically, HbA1c fell with increasing duration between clinic visits with those visiting annually having the lowest HbA1c (9.0% ± 0.2% vs 7.1% ± 0.7%). Compliance with lifestyle and exercise resulted in lower HbA1c and blood lipids. Poor client education on glucometer usage, administration of insulin and non-compliance with diet and exercise were associated with higher HbA1c.

关键词： Glucometer Blood Glucose Glycemic Control Lipid Profile

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The Honeymoon of China and Mexico

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China's Foreign Trade 2008年第15期 38-38页

作者： hellen

For China and Mexico,the just past July 2008 is their'honey- moon',as their relations have been consolidated by a series of big *** three days later after Mexican President Felipe Calderon Hi- nojosa met his counterpart Hun Jintao at G8,he paid an official visit to China on July 9,and agreed with Chinese top lead- ers on some significant *** was the first China tour that Calderon paid since he took office in December 2006.

关键词：中国墨西哥国际贸易外贸关系

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挪or不挪?

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甲壳虫 2008年第10期 40-41页

作者：高高 hellen 张萧隆李家元

文化挪移对于我们普通消费者来说,是个很抽象的概念,我们购物时很少会仔细分析其中的深意,只是单纯的觉得这样的产品更有特色,能够突出使用者的个性。我想这就是所谓的人们爱美天性的自然选择。能够将各种艺术形式里的符号交叉使用,并... 详细信息

文化挪移对于我们普通消费者来说,是个很抽象的概念,我们购物时很少会仔细分析其中的深意,只是单纯的觉得这样的产品更有特色,能够突出使用者的个性。我想这就是所谓的人们爱美天性的自然选择。能够将各种艺术形式里的符号交叉使用,并融会贯通,从某种程度上来说是人类的一种进步,如今随着数字科技的发展,文化挪用变得更加容易。拿最普通的卡通形象来说,

关键词：卡通形象艺术形式数字科技交叉使用 or 前卫艺术家视觉符号艺术元素艺术创造实验室阶段

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Seed Priming and Tolerance to Salt and Water Stress in Divergent Grain Sorghum Genotypes

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American Journal of Plant Sciences 2018年第4期9卷 606-616页

作者： Charles Lobo Pinheiro hellen Thayse Nascimento Araújo Selma Freire de Brito Marcos da Silva Maia Jesimiel da Silva Viana Sebastiao Medeiros Filho Department of Plant Science Federal University of CearáFortalezaBrazil

Tolerance to water and salt stress during germination and growth of agricultural species might have superior results when seeds are submitted to priming processes. The objective of the present study was to evaluate the use of hydropriming and hormonal priming with gibberellic acid (GA3) on the tolerance of divergent genotypes of sorghum to salt and water stress during germination and seedling growth. The genotypes analyzed were cultivar BRS 330 and lineage 201420, which are the most and least tolerant to water and salt stress, respectively. Sowing was undertaken under control (no stress), water stress (-0.6 MPa), and salt stress (20 dS·m-1) conditions, and the seeds were subjected to the following treatments: control-no immersion;hydropriming-immersion for 2 hours in distilled water;and hormonal priming-immersion in GA3 solutions, at concentrations of 50, 75, and 100 ppm, for 2 hours. After soaking, the seeds were dried for 24 hours at a temperature of 30°C ± 2°C. The variables analyzed were percentage and germination speed index, root and shoot lengths, and root/shoot ratio. The stress conditions analyzed negatively affected the two genotypes;however, the seeds that underwent priming processes improved the performance of the genotypes under salt and water stress conditions, especially when using seeds of the more tolerant genotype (BRS 330) subjected to hormonal priming at 100 ppm GA3 concentration.

关键词： Hydropriming Hormonal Priming Gibberellic Acid Sorghum bicolor

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海伦·凯勒自传

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2003年

作者：（美）海伦·凯勒（ hellen Keller）张雪兰谢萍译

虽然孩提时代的欢与悲伤经过时间的冲刷大都失去了本地的颜色，许多在我早期记忆中举足轻重的事件在成长的兴奋中也被渐渐遗忘，然而，某些画面在脑海中依然是鲜明生动的，它不时地闪现，带给我的人生或多少的影响。为了不使我的传记变... 详细信息

ISBN: (数字)7801663152

ISBN: (纸本)7801663152

虽然孩提时代的欢与悲伤经过时间的冲刷大都失去了本地的颜色，许多在我早期记忆中举足轻重的事件在成长的兴奋中也被渐渐遗忘，然而，某些画面在脑海中依然是鲜明生动的，它不时地闪现，带给我的人生或多少的影响。为了不使我的传记变得冗长乏味，我将节选一生中最有趣也最重要的片段，来讲述我生命的故事。

关键词：凯勒自传

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