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Interest of D-dimer level,severity of COVID-19 and cost of management in Gabon

World Journal of Critical Care medicine 2025年第1期14卷 91-99页

作者： Berthe A Iroungou Arnaud Nze O helga m kandet y Neil-michel Longo-Pendy Nina D mezogho-Obame Annicet-Clotaire Dikoumba Guignali L mangouka Unitémixte de Recherche Centre International de Recherches Médicales de Franceville et le Service de SantéMilitaireLibreville 20404EstuaireGabon AP-HP Health Economics Research UnitHtel Dieu HospitalParis 75004Ilede-FranceFrance Laboratory Hôpital D'Instruction des Armées D'AkandaLibreville 20404EstuaireGabo Unitéde Recherche enÉcologie de la Santé Centre Interdisciplinaire de Recherches Médicales de FrancevilleFranceville 769Gabon Laboratory Hôpital D'Instruction des Armées Omar Bongo OndimbaLibreville 20404EstuaireGabon Department of medecine Polyvalente Hôpital D'Instruction des Armées Omar Bongo OndimbaLibreville 20404EstuaireGabon

BACKGROUND Coronavirus disease 2019(COVID-19)is strongly associated with an increased risk of thrombotic events,including severe outcomes such as pulmonary *** D-dimer levels are a critical biomarker for assessing this *** Gabon,early implementation of anticoagulation therapy and D-dimer testing has been crucial in managing *** study hypothesizes that elevated Ddimer levels are linked to increased COVID-19 *** To determine the impact of D-dimer levels on COVID-19 severity and their role in guiding clinical *** This retrospective study analyzed COVID-19 patients admitted to two hospitals in Gabon between march 2020 and December *** study included patients with confirmed COVID-19 diagnoses and available D-dimer measurements at *** on demographics,clinical outcomes,D-dimer levels,and healthcare costs were ***-19 severity was classified as non-severe(outpatients)or severe(inpatients).A multivariable logistic regression model was used to assess the relationship between D-dimer levels and disease severity,with adjusted odds ratios(OR)and 95%*** A total of 3004 patients were included,with a mean age of 50.17 years,and the majority were female(53.43%).Elevated D-dimer levels were found in 65.81%of patients,and 57.21%of these experienced severe *** analysis showed that patients with elevated D-dimer levels had 3.33 times higher odds of severe COVID-19(OR=3.33,95%CI:2.84-3.92,Pmained significant in the multivariable analysis,adjusted for age,sex,and year of *** financial analysis revealed a substantial burden,particularly for uninsured *** D-dimer predicts COVID-19 severity and guides treatment,but the high cost of anticoagulant therapy highlights the need for policies ensuring affordable access in resource-limited settings like Gabon.

关键词： D-dimers COVID-19 management Disease severity Healthcare costs Gabon

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A behavioral ecology approach to traffic accidents:Interspecific variation in causes of traffic casualties among birds

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Zoological Research 2011年第2期32卷 115-127页

作者： Anders Pape mller helga Erritze Johannes Erritze Department of Ecology Systematics and Evolution CNRS UMR 8079 University of Paris-South Batiment 362 F-91405 Orsay Cedex France Taps Old Rectory DK-6070 Christiansfeld Denmark

Birds and other animals are frequently killed by cars,causing the death of many million individuals per *** some species are killed more often than others has never been *** this work hypothesized that risk taking behavior may affect the probability of certain kinds of individuals being killed disproportionately ***,behavior of individuals on roads,abundance,habitat preferences,breeding sociality,and health status may all potentially affect the risk of being killed on *** used information on the abundance of road kills and the abundance in the surrounding environment of 50 species of birds obtained during regular censuses in 2001 2006 in a rural site in Denmark to test these *** frequency of road kills increased linearly with abundance,while the proportion of individuals sitting on the road or flying low across the road only explained little additional variation in frequency of road *** having accounted for abundance,we found that species with a short flight distance and hence taking greater risks when approached by a potential cause of danger were killed disproportionately *** addition,solitary species,species with a high prevalence of Plasmodium infection,and species with a large bursa of Fabricius for their body size had a high susceptibility to being killed by *** findings suggest that a range of different factors indicative of risk-taking behavior,visual acuity and health status cause certain bird species to be susceptible to casualties due to cars.

关键词： Birds Blood parasites Flight behavior Flight distance Habitat selection Sociality

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生态农业和有机农业的创新

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中国生态农业学报（中英文） 2021年第3期29卷 423-430页

作者： Urs Niggli Qiyan Wang-muller helga Willer Jacques Fuchs Research Institute of Organic Agriculture(FiBL) Vienna A-1010Austria Research Institute of Organic Agriculture(FiBL) Frick CH-5070Switzerland Swiss Chinese Herbal medicine and Functional Food Innovation Center(SwissHerbs) Zürich CH-8008Switzerland

现代农业系统在明显提高产量、保证粮食安全的同时,也对人类健康和地球的可持续性产生了影响。在持续不断的严重环境破坏和自然资源毁坏的背景下,建立可持续的农业生产方式至关重要。生态农业和有机农业是减少生态可持续性和生产力及社... 详细信息

现代农业系统在明显提高产量、保证粮食安全的同时,也对人类健康和地球的可持续性产生了影响。在持续不断的严重环境破坏和自然资源毁坏的背景下,建立可持续的农业生产方式至关重要。生态农业和有机农业是减少生态可持续性和生产力及社会可持续之间权衡关系的重要方法。这两种农业方法都属生态集约化范畴,均具有减少环境污染的巨大潜力;然而,生态农业和有机农业常导致产量降低。虽然产量降低带来的损失可以通过改变人们的饮食习惯来弥补(如减少食物浪费、减少食用精饲料喂养的肉类),但是,由于全球的发展趋势与之相反,因此本文探讨了通过科学研究寻求新的解决方案前景来提高低投入农业系统作物产量的可能性。为权衡生产力与可持续发展的关系,使生态农业和有机农业有助于粮食安全,我们对未来研究提出5点建议:1)农场和田地的景观设计与复合种植模式、2)数字化技术的应用、3)以农田低投入为目标的作物育种、4)农业废弃物的高质量循环利用和5)非化学作物保护。

关键词：生态农业生产力有机农业系统导向性研究

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影响熔融静电纺聚丙烯纤维直径的工艺因素

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纺织学报 2016年第11期37卷 14-18,25页

作者：梁超胡春艳阎克路朱晓敏 THOmAS helga 东华大学化学化工与生物工程学院上海201620 国家染整工程技术研究中心上海201620 德国羊毛研究所亚琛d52056

针对聚丙烯熔融静电纺纤维直径难以细化问题,以熔体流量、聚合物熔体温度、施加电压、喷丝头与接收台的接收距离、电场力等为影响因素进行研究。结果表明:流量为0.05 m L/h时可以纺出连续的纤维且纤维直径也随流量的增大而增加;当聚合... 详细信息

针对聚丙烯熔融静电纺纤维直径难以细化问题,以熔体流量、聚合物熔体温度、施加电压、喷丝头与接收台的接收距离、电场力等为影响因素进行研究。结果表明:流量为0.05 m L/h时可以纺出连续的纤维且纤维直径也随流量的增大而增加;当聚合物熔体/喷丝头温度超过260℃/280℃时,继续升高温度纤维直径不会继续降低;电场力恒定时,随着接收距离增加,纤维直径减小的趋势逐渐变缓,到30 mm之后,纤维直径基本不变。考虑综合因素,最终选取的工艺参数:熔体流量为0.05 m L/h,聚合物熔体/喷丝头温度为260℃/280℃,电压为-24.6 k V,距离为30 mm,在此条件下纺得纤维的平均直径为6.23μm,标准差为1.42。

关键词：聚丙烯熔融静电纺影响因素纤维直径

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促进慢性阻塞性肺疾病哮喘患者自我监控空气质量的护理干预措施: 整合性综述

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International Journal of Nursing Sciences 2024年第1期11卷 46-56页

作者： Bruna F.Sebastiao Raquel m.Hortelao Sara S.Granadas Jose m.Faria Joana R.Pinto helga Rafael Henriques Nursing School of Lisbon LisbonPortugal Hospital Center of Central Lisbon Portugal CUF Tejo Hospital LisbonPortugal University Hospital Center of Northern Lisbon LisbonPortugal Nursing Research Innovation and Development Centre of Lisbon(CIDNUR)LisbonPortugal

目的哮喘-慢性阻塞性肺疾病肺重叠症(Asthma-chronie obst ructive pulmonary disease overlap,A-CO)患者的生活质量较低,肺功能较差,病情经常加重。由于暴露于污染环境会加重其症状,增加发病率和病死率,环境管理对其至关重要。旨在通... 详细信息

目的哮喘-慢性阻塞性肺疾病肺重叠症(Asthma-chronie obst ructive pulmonary disease overlap,A-CO)患者的生活质量较低,肺功能较差,病情经常加重。由于暴露于污染环境会加重其症状,增加发病率和病死率,环境管理对其至关重要。旨在通过系统性综述,寻找证据,以指导制订护理干预措施,促进ACO患者对空气质量的自我管理。方法2023年3月 ,系统检索CINAHL、medline、Academie Search Complete .Scopus、WebofScience、Cochrane图书馆、乔安娜布里格斯研究所(JoannaBriggsInstitute,JBI)循证实践数据库,以及GoogleScholar。对纳人研究进行数据提取和综合,并对护理干预措施进行分类。采用JBI研究质量评估工具进行方法学质量评估。结果共纳入5篇来自不同国家的研究。促进ACO患者自我监控空气质量的干预措施包括:警觉性干预措施(医务人员定期巡诊、进行症状评估),监测干预措施(监测室内外诱发因素) ,教育干预措施(空气质量警报、避免接触过敏原),以及相关政策的影响,如无烟政策和改善空气质量的综合战略。尽管这些研究报告了不同的干预措施,方法质量也存在差异,但这些干预措施显示了预防患者病情恶化、尽量减少急诊就诊和住院治疗的潜力。这些关键点可作为护理干预措施的关键组成部分。结论有必要采取全面措施,让护士参与促进患者自我监控空气质量的多学科团队.提高认识、制订和实施护理干预,从而使ACO患者受益。同时,需要进--步开展研究,以扩大证据基础并完善这些干预措施。

关键词：空气质量哮喘哮喘-慢阻肺重叠慢性病慢性阻塞性肺疾病护理自我管理

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Imaging-based diagnosis of acute renal allograft rejection

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World Journal of Transplantation 2016年第1期6卷 174-182页

作者： Gerold Th?lking Katharina Schuette-Nuetgen Dominik Kentrup helga Pawelski Stefan Reuter Department of medicine D Division of General Internal Medicine Nephrology and Rheumatology University Hospital of Münster

Kidney transplantation is the best available treatment for patients with end stage renal disease. Despite the introduction of effective immunosuppressant drugs, episodes of acute allograft rejection still endanger graft survival. Since efficient treatment of acute rejection is available, rapid diagnosis of this reversible graft injury is essential. For diagnosis of rejection, invasive core needle biopsy of the graft is the "gold-standard". However, biopsy carries the risk of significant graft injury and is not immediately feasible in patients taking anticoagulants. Therefore, a non-invasive tool assessing the whole organ for specific and fast detection of acute allograft rejection is desirable. We herein review current imaging-based state of the art approaches for non-invasive diagnostics of acute renal transplant rejection. We especially focus on new positron emission tomography-based as well as targeted ultrasoundbased methods.

关键词： Acute allograft rejection Imaging Positron emission tomography Ultrasound magnetic resonance imaging Single photon emission computed tomography Kidney transplantation Renal

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Demonstration of no catalytical activity of Fe-N-C and Nb-N-C electrocatalysts toward nitrogen reduction using in-line quantification

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Susmat 2022年第4期2卷 476-486页

作者： Arnar Sveinbjörnsson Anna Bergljót Gunnarsdóttir Erin B.Creel Camila Pía Canales Barr Zulevi Xiang Lyu Charl J.Jafta Egill Skúlason Alexey Serov helga Dögg Flosadóttir Atmonia ehf. ReykjavíkIceland Faculty of Industrial Engineering Mechanical Engineering and Computer ScienceUniversity of IcelandVR-IIIReykjavíkIceland Electrification and Energy Infrastructures Division Oak Ridge National LaboratoryOak RidgeTennesseeUSA Pajarito Powder LLC(PPC)AlbuquerqueNew MexicoUSA Science Institute University of IcelandVR-IIIReykjavíkIceland

Ammonia(NH3)production via the electrochemical nitrogen reduction reaction(NRR)is a promising method for sustainable generation of this important *** are ongoing in finding an efficient,stable,and selective catalyst that will enable the ***,progress is hindered in the field due to lack of reproducibility,most likely a consequence of reports of false-positive results due to improper measurement control and *** this study,we explore the NRR activity of a promising class of single atom catalysts,transition metal-nitrogen-carbon(m-N-C)*** a state-of-the-art in-line ammonia quantification methodology,with detection limit as low as 1 ppb for ammonia,we show that single atom Nb and Fe embedded in a stable carbon and nitrogen framework do not electrochemically reduce N_(2) to NH_(3).Critically,this demonstrates that our experimental setup with in-line sequential injection analysis successfully excludes ammonia contamination from the gas supply and atmospheric sources,allowing for thorough and high-throughput examination of potential NRR catalysts.

关键词： ammonia synthesis electrocatalysis nitrogen electroreduction NRR single atom catalyst

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Group Exercise versus Personal Training for Prostate Cancer Patients: A Pilot Randomized Trial

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Journal of Cancer Therapy 2012年第2期3卷 146-156页

作者： Daniel Santa mina Paul Ritvo Andrew G. matthew Ajay Rampersad helga Stein Angela m. Cheung John Trachtenberg Shabbir m. H. Alibhai Kinesiology Program University of Guelph-Humber Toronto Canada School of Kinesiology and Health Science York University Toronto Canada The Department of Surgical Oncology Princess Margaret Hospital Toronto Canada University Health Network Toronto Canada

Background: Previous studies have demonstrated psychosocial and physical benefit from exercise for older men treated with androgen deprivation therapy (ADT) for prostate cancer (PCa). To date, different intervention delivery methods have not been assessed. This study compared the effect of group-based exercise (GBE) to personal training (PT) in men undergoing ADT for PCa. methods: 13 participants (mean age = 68.2, SD = 7.2) were randomly assigned to GBE or PT for 8 weeks. Participants exercised for 60 minutes three times per week at a moderate-vigorous intensity. Results: 10 participants completed the intervention. At post-intervention, the PT group improved: fatigue, systolic BP, waist circumference, body fat percentage, and maximal leg strength;participants in the GBE group improved leg strength. At 8 weeks, maximal upper body strength in the PT group was greater than the GBE group. There were no adverse events associated with moderate-high intensity training in this population of older men. Conclusion: PT may be more efficacious than GBE in improving several physical fitness outcomes and fatigue in men with PCa who are androgen deprived. Due to the small sample size and attrition, these results require cautious interpretation and confirmation from adequately powered trials.

关键词： Group Exercise Personal Training Prostate Cancer Pilot Randomized Trial

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Effect of Freshwater Influx on Phytoplankton in the mandovi Estuary (Goa, India) during monsoon Season: Chemotaxonomy

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Journal of Water Resource and Protection 2013年第3期5卷 349-361页

作者： Sushma G. Parab S. G. Prabhu matondkar helga do R. Gomes Joaquim I. Goes Lamont Doherty Earth Observatory at Columbia University New York USA National Institute of Oceanography Dona Paula Goa India

The mandovi estuary is a prominent water body that runs along the west coast ofIndia. It forms an estuarine network with the adjacent Zuari estuary, connected via the Cumbharjua canal. The physico-chemical conditions seen in the mandovi estuary are influenced by two factors: the fresh water runoff during the monsoon season (June-September) and the tidal influx of coastal seawater during the summer (October to may) season. However, the effects of monsoon related changes on the phytoplankton of the mandovi estuary are not yet fully understood. An attempt to understand the same has been made here by applying the process of daily sampling at a fixed station throughout the monsoon season. It was noticed that the onset of the monsoon is responsible for an increase in nitrate levels upto 26 μm from a (chl a) as high as 14 μg·L-1 during the same period. The phytoplankton population was observed through both chemotaxonomy and microscopy and was found to be composed mainly of diatoms. CHEmTAX analysis further uncovers the presence of several other groups of phytoplankton, the presence of which is yet to be reported in many other tropical estuaries. It includes chrysophytes, cyanobacteria, prasinophytes, prymnesiophytes and chlorophytes. The appearance of phytoplankton groups at various stages of the monsoon was recorded, and this data is discussed in relation to environmental changes in the mandovi estuary during the monsoon season.

关键词： Phytoplankton Pigment Analysis monsoon Freshwater Runoff CHEmTAX

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促进慢性阻塞性肺疾病哮喘患者自我监控空气质量的护理干预措施:整合性综述（英文）

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International Journal of Nursing Sciences 2024年第1期 46-56页

作者： Bruna F.Sebasti?o Raquel m.Hortel?o Sara S.Granadas José m.Faria Joana R.Pinto helga Rafael Henriques Nursing School of Lisbon Hospital Center of Central Lisbon CUF Tejo Hospital University Hospital Center of Northern Lisbon Nursing Research Innovation and Development Centre of Lisbon (CIDNUR)

目的哮喘-慢性阻塞性肺疾病肺重叠症(Asthma-chronic obstructive pulmonary disease overlap,ACO)患者的生活质量较低,肺功能较差,病情经常加重。由于暴露于污染环境会加重其症状,增加发病率和病死率,环境管理对其至关重要。旨在通过... 详细信息

目的哮喘-慢性阻塞性肺疾病肺重叠症(Asthma-chronic obstructive pulmonary disease overlap,ACO)患者的生活质量较低,肺功能较差,病情经常加重。由于暴露于污染环境会加重其症状,增加发病率和病死率,环境管理对其至关重要。旨在通过系统性综述,寻找证据,以指导制订护理干预措施,促进ACO患者对空气质量的自我管理。方法 2023年3月,系统检索CINAHL、medline、Academic Search Complete、Scopus、Web of Science、Cochrane图书馆、乔安娜布里格斯研究所(Joanna Briggs Institute,JBI)循证实践数据库,以及Google Scholar。对纳入研究进行数据提取和综合,并对护理干预措施进行分类。采用JBI研究质量评估工具进行方法学质量评估。结果共纳入5篇来自不同国家的研究。促进ACO患者自我监控空气质量的干预措施包括:警觉性干预措施(医务人员定期巡诊、进行症状评估),监测干预措施(监测室内外诱发因素),教育干预措施(空气质量警报、避免接触过敏原),以及相关政策的影响,如无烟政策和改善空气质量的综合战略。尽管这些研究报告了不同的干预措施,方法质量也存在差异,但这些干预措施显示了预防患者病情恶化、尽量减少急诊就诊和住院治疗的潜力。这些关键点可作为护理干预措施的关键组成部分。结论有必要采取全面措施,让护士参与促进患者自我监控空气质量的多学科团队、提高认识、制订和实施护理干预,从而使ACO患者受益。同时,需要进一步开展研究,以扩大证据基础并完善这些干预措施。

关键词：空气质量哮喘哮喘-慢阻肺重叠慢性病慢性阻塞性肺疾病护理自我管理

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