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Biquinho pepper(Capsium chinense):Bioactive compounds,in vivo and in vitro antioxidant capacities and anti-cholesterol oxidation kinetics in fish balls during frozen storage

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Food Bioscience 2022年第3期47卷 512-523页

作者： Bárbara Jardim Mariano Vanessa Sales de Oliveira Davy William Hidalgo Chávez Rosane Nora Castro Cristiano Jorge Riger Jéssica Sodré Mendes Marcelo da Costa Souza Alexandra Christine helena Frankland Sawaya Geni Rodrigues Sampaio Elizabeth Aparecida Ferraz da Silva Torres Tatiana Saldanha Department of Food Technology Institute of TechnologyUniversity Federal Rural of Rio de JaneiroRodovia Br 465SeropédicaRJ23890-000Brazil Department of Chemistry Institute of ChemistryUniversity Federal Rural of Rio de JaneiroRodovia Br 465SeropédicaRJ23890-000Brazil Department of Biochemistry Institute of ChemistryUniversity Federal Rural of Rio de JaneiroRodovia Br 465SeropédicaRJ23890-000Brazil Department of Botany Institute of Biological Sciences and HealthUniversity Federal Rural of Rio de JaneiroRodovia Br 465SeropédicaRJ23890-000Brazil Faculty of Pharmaceutical Science University of CampinasUNICAMPCampinasSPBrazil Department of Nutrition School of Public HealthUniversity of São Paulo (USP)Ave.Dr.Arnaldo715São PauloSP01246-904Brazil

The present study reports bioactive constituents from biquinho pepper,such as carotenoids,capsaicinoids,and capsinoids,identified by *** pepper extract showed an antioxidant potential by DPPH(33.17±0.08%),ORAC(32.35±0.02μM TE/g),β-carotene/linoleic acid(55.80±1.30%),and FRAP(315.88±4.23μmol TE/g)***,in vivo antioxidant analyses demonstrated that the pepper extract(170μg/mL)decreased the damage promoted by H_(2)O_(2) in Saccharomyces cerevisiae *** balls were prepared using different concentrations of pepper(0.0%,0.5%,0.75%,1.0%)to investigate its antioxidant effect during frozen *** pepper effectively reduced the formation of cholesterol oxides and preserved essential fatty acids,mainly in samples containing 1.0%of ***,this treatment was more efficient than sodium erythorbate(p0.8).

关键词： Bioactive compounds Capsicum chinense Cholesterol oxides Frozen storage Natural antioxidants Unsaturated lipids

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最好的新年决心

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英语教师 2007年第1期7卷 1-1页

作者： helena 栾薇

去年,我选择了"每日行一善事"而非某个远大的梦想作为我新年决心中的一项,因为我想我所需要的只是一些简单易行且对我来说更有意义的燕雀之志。所以一直以来我都在留心寻找做善事的机会。原来它们俯首皆是!有些是隐秘的善举。我个人最... 详细信息

去年,我选择了"每日行一善事"而非某个远大的梦想作为我新年决心中的一项,因为我想我所需要的只是一些简单易行且对我来说更有意义的燕雀之志。所以一直以来我都在留心寻找做善事的机会。原来它们俯首皆是!有些是隐秘的善举。我个人最钟爱的就是抓住停车场的购物车,并把它推回店内。这样,

关键词：停车场购物车新年简单易行燕雀每日选择机会意义停车位

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Ubuntu——Linux开源的明日之星

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程序员 2006年第12期 25-25页

作者： helena 王开源

Mark Shuttieworth。Ubuntu创始人，1975年生于南非，现居住于英国伦敦。Mark毕业于开普敦大学金融与信息科学专业。就读期间，他创建了安全咨询公司Thawte Consulting，后来以5．75亿美元的身价卖给了美国VeriSign公司，由此一跃成为... 详细信息

Mark Shuttieworth。Ubuntu创始人，1975年生于南非，现居住于英国伦敦。Mark毕业于开普敦大学金融与信息科学专业。就读期间，他创建了安全咨询公司Thawte Consulting，后来以5．75亿美元的身价卖给了美国VeriSign公司，由此一跃成为南非最年轻有为的富翁。随后，Mark创办了HBD风险投资公司和Shuttleworth基金会。2004年9月，他发起创立了Ubuntu体系，并出资1000万美元建立了Ubuntu基金会。Mark现在成立了他的公司Canonical并担任董事长。

关键词： Linux Mark 开源信息科学咨询公司风险投资基金会创始人

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Understanding the paranoid psychosis of James:Use of the repertory grid technique for case conceptualization

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World Journal of Psychiatry 2016年第3期6卷 381-390页

作者： helena García-Mieres Susana Ochoa Marta Salla Raquel López-Carrilero Guillem Feixas Development Unit of Parc Sanitari Sant Joan de Déu Department of Personality Assessment and Psychological TreatmentsFaculty of PsychologyUniversity of Barcelona

In this paper we illustrate the potential of the repertory grid technique as an instrument for case formulation and understanding of the personal perception and meanings of people with a diagnosis of psychotic *** this purpose,the case of James is presented:A young man diagnosed with schizophrenia and personality disorder,with severe persecutory delusions and other positive symptoms that have not responded to antipsychotic medication,as well with depressive *** case was selected because of the way his symptoms are reflected in his personal perception of self and others,including his main persecutory figure,in the different measures that result from the analysis of his repertory *** key clinical hypotheses and possible targets for therapy are discussed.

关键词： Persecutory delusions Personal constructs Schizophrenia Repertory grid technique Case formulation

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Correction to: Replication of LZTFL1 Gene Region as a Susceptibility Locus for COVID-19 in Latvian Population

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Virologica Sinica 2021年第6期36卷 1692-1692页

作者： Raimonds Rescenko Raitis Peculis Monta Briviba Laura Ansone Anna Terentjeva helena Daiga Litvina Liga Birzniece Kaspars Megnis Oksana Kolesova Baiba Rozentale Ludmila Viksna Vita Rovite Janis Klovins Latvian Biomedical Research and Study Centre Riga 1067Latvia Riga Stradins University Riga 1007Latvia

Correction to:Virologica Sinica https://***/10.1007/s12250-021-00448-x Due to our oversight,the author list of reference“Promchan *** *** M(2020)Leucine zipper transcription factor-like I binds adaptor protein comple... 详细信息

关键词： Replication LZTFL1 traffic

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衰退中的甜味剂

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财经文摘 2009年第5期 76-76页

作者： helena Bschmann 孙玮（编译）《时代周刊》

复活节前几天，劳瑞·贝蒂尼在日内瓦市中心Manor超级市场的货架间选购节日商品。“尽管经济不好，但在我的购物清单上巧克力一直排在前面。”一边说着，她把一份金色锡箔纸包装的瑞士莲（Lindt）牌牛奶巧克力兔放进购物车。

关键词：甜味剂超级市场巧克力购物车复活节市中心日内瓦纸包装

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Contribution of the Advanced Research Laboratories at the Noguchi Memorial Institute for Medical Research (NMIMR) to SARS-CoV-2 Testing in Ghana

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Health 2022年第1期14卷 125-136页

作者： Darius N. K. Quansah Ivy A. Asante Evelyn Y. Bonney Evangeline Obodai Mildred A. Adusei-Poku James Aboagye Susan Adu-Amankwah Samuel Adjei Richard Akuffo helena Lamptey George B. Kyei John K. Odoom William K. Ampofo Joseph H. K. Bonney Department of Virology Noguchi Memorial Institute for Medical Research University of Ghana Legon Accra Ghana West African Centre for Cell Biology of Infectious Pathogens College of Basic and Applied Sciences University of Ghana Legon Accra Ghana Department of Medical Microbiology University of Ghana Medical School Accra Ghana Medical and Scientific Research Directorate University of Ghana Medical Centre Legon Accra Ghana Department of Epidemiology Noguchi Memorial Institute for Medical Research University of Ghana Legon Accra Ghana Department of Animal Experimentation Noguchi Memorial Institute for Medical Research University of Ghana Legon Accra Ghana Department of Immunology Noguchi Memorial Institute for Medical Research University of Ghana Legon Accra Ghana

In March 2020, the first cases of SARS-CoV-2 were reported in Accra, Ghana. These initial cases were diagnosed at the Advanced Research Laboratories (ARL) of the Noguchi Memorial Institute for Medical Research (NMIMR), University of Ghana. The ARL which hitherto was used for routine clinical research in viral, bacteria and immunological studies has since been the facility of choice for testing for all suspected cases of COVID-19 submitted from across Ghana and beyond. The success of testing at the ARL hinged on the availability of several laboratory spaces furnished with state-of-the-art diagnostic equipment and working aids. During the “peak season” where overwhelming numbers of clinical specimens were received, the ARL processed and got results for close to four thousand samples daily. After general disinfection and re-bagging into smaller numbers, at the entrance of the ARL, the samples are taken to a central receiving laboratory, where they are received and entered in a database with accompanying case investigation forms. All samples that are successfully sorted and matched are sent to general laboratories for nucleic acid extraction and then referred to the Instrumentation laboratory for real time reverse-transcription polymerase chain reaction (RT-PCR). When the RT-PCRs were completed, results were analysed and transmitted via email and/or local network to the data reporting office. The data managers then reported results to the investigators and the Ghana Health Service (GHS). Additionally, the ARL provided a next-generation Genome Sequencing platform in partnership with the West African Centre for Cell Biology of Infectious Pathogens at the University of Ghana, which was essential in reporting the genome data of the circulating variants of SARS-CoV-2 in Ghana. Conclusively, it is worth noting, that the NMIMR fulfilled its mandate of supporting the country with specialized diagnostics through the judicious use of the ARL for SARS-CoV-2 testing, from sample re

关键词： Advanced Research Laboratories Polymerase Chain Reaction Severe Acute Respiratory Syndrome—Corona Virus 2 Corona Virus Disease 2019

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Management of Gestational Trophoblast Disease: A Review Integrative National and International Guidelines

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Health 2022年第12期14卷 1321-1333页

作者： Marcela Curvêllo Beltrão Maira de Lima Oliveira Mota Elizabeth Bacha Lusitania Maria de Barros Livia helena Gomes de Barros Brandão Nelson Henriky Felix Mascarenhas Tallys Leandro Barbosa da Silva Maria Fernanda Telles Pires de Souza Séfora Maria Fragoso Braga Victoria de Oliveira Carmo Borges Centro Universitário Tiradentes (UNIT) Maceió Brasil Instituto de Medicina Integral Professor Fernando Figueira (IMIP) Pernambuco Brasil Estácio de Juazeiro do Norte (FMJ) Ceará Brasil Universidade Federal de Alagoas (UFAL) Maceió Brasil Sã o Leopoldo Mandic Campinas Brasil Hospital Regional de Arapiraca Arapiraca Brasil

GTD (Gestational Trophoblastic Disease) is a pathology that encompasses benign and malignant clinical forms, affects women of childbearing age, has a variable incidence and is more frequent in developing or underdeveloped countries, colliding with the economic barrier. The frequent absence of clear protocols and guidelines for the correct diagnosis and treatment of the aforementioned pathology results in inadequate risk classification, imprecise treatment and failed post-therapeutic observation, increasing the risk of relapses, morbidity and mortality. The present study aims to compare the different national and international guidelines in the management of GTD, through an integrative review. Nine articles were selected and it was observed that the main international reference centers are agreed with the management suggested by the IFGO (International Federation of Gynecology and Obstetrics), being the conduct in the Hydatidiform Mole (HM): evacuation by suction and curettage under ultrasound guidance, followed by hCG monitoring every 1 - 2 weeks until normalized;in low-risk GTN (Gestational Trophoblastic Neoplasm): chemotherapy with methotrexate or actinomycin D, in high-risk: EMA/CO protocol, in ultra-high-risk EMA/PE, methotrexate with radiotherapy for brain metastases. All medical societies recommend the registration of these patients in GTD screening centers, endorse the use of the IFGO scoring system (2000) and recommend the surgical management of placental site trophoblastic or epithelioid tumors, as chemotherapy is less effective in these cases. The controversies are in the proper follow-up after the treatment of HM, use of ultrasound to evacuate the uterus, administration of anti-D immunoglobulin, time of oxytocin infusion and rescue regimens that can be used in cases of resistant or recurrent GTN. Establishing and complying with consistent guidelines can improve patient care, with early diagnosis of the pathology and its complications, reducing the rate of

关键词： Guidelines Gestational Trophoblastic Disease Treatment

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Influence of Cleaning Time in Household Reservoirs on Trihalomethane Formation in Treated Water

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Journal of Water Resource and Protection 2019年第11期11卷 1389-1397页

作者： Ricardo Andreola Péricles Martim Reche Gervasio Tono Graciene de Souza Bido Daniele Fernanda Felipe Anny Rosi Mannigel André Ribeiro da Costa Gisele Caroline Novakowski Letycia Lopes Ricardo Flavia helena de Moura Liborio Stephane Raquel Almeida Velande da Fonseca Isabela Silva de Oliveira Giuliano Patrick Rasera Thaise Moser Teixeira University Center of Maringá (UNICESUMAR) Master in Science Technology and Food Safety Maringá Brazil State University of Ponta Grossa Campus Uvaranas Ponta Grossa Brazil State University of Maringá Maringá Brazil Federal University of Paraná Palotina Brazil

Chlorination is an efficient and low-cost technique in disinfecting water for public water supply. However, during the process, the formation of undesirable by-products called halogen compounds, such as trihalome-thanes (THMs), occurs. Some of these compounds are proven to be carcinogenic to laboratory animals. The goal of this study was to investigate the occurrence of THMs in household reservoirs and the influence of cleaning time of these reservoirs on the formation of THMs. A total of 103 households were investigated in the city of Maringá, State of Paraná, Brazil. The residences were classified according to the cleaning time of the reservoir into: up to one year, one to two years and more than two years. Samples were taken from the reservoirs and total trihalomethanes (THMt) were analyzed by gas chromatography (GC-MS), total organic carbon (TOC) by means of a Hach kit for low concentrations and free residual chlorine (CLres) by means of a kit for in loco determination. According to the results, the highest concentrations of THMt were observed in the reservoirs with cleaning time of more than 2 years. However, no amount has exceeded the maximum limit allowed by law. In general, the longer the time for cleaning the reservoir, the greater the degradation of water quality in THMt.

关键词： Trihalomethanes Distribution Network Chlorination Cancer

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难忘的考试

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少年文摘 2007年第11期 23-23页

作者： helena 朱孝萍

自从升入九年级开始上健康课以后,我们教室里的一块黑板上,就一直画着一幅人体图。图上标着人体主要骨骼和肌肉的名称和位置。在那个学期里,虽然这幅图一直画在黑板上,但老师从来没有提到过它。期末考试的时候,我们发现那块黑板被擦干净了,

关键词：黑板人体骨骼期末考试试卷名称老师位置健康课教育

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