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Ventilation practices in burn patients—an international prospective observational cohort study

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Burns & Trauma 2021年第1期9卷 47-57页

作者： Gerie J.Glas Janneke Horn markus W.Hollmann Benedikt Preckel Kirsten Colpaert manu malbrain Ary Serpa Neto Karim Asehnoune marcello Gamma de Abreu Ignacio martin-Loeches Paolo Pelosi Folke Sjoerg Jan m.Binnekade Berry Cleffken Nicole P.Juffermans Paul knape Bert G.Loef David P.mackie Perenlei Enkhbaatar Nadia Depetris Anders Perner Eva Herrero Lucia Cachafeiro marc Jeschke Jeffrey Lipman matthieu Legrand Johannes Horter Athina Lavrentieva Alex Kazemi Anne Berit Guttormsen Frederik Huss mark Kol helen Wong Therese Starr Luc De Crop Wilson de Oliveira Filho Joa manoel Silva Junior Cintia m.C.Grion marjorie Burnett Frederik mondrup Francois Ravat mathieu Fontaine Renan Le Floch mathieu Jeanne morgane Bacus maite Chaussard marcus Lehnhardt Bassem Daniel mikhail Jochen Gille Aidan Sharkey Nicole Trommel Auke C.Reidinga Nadine Vieleers Anna Tilsley Henning Onarheim maria Teresa Bouza Alexander Agrifoglio Filip Fredén Tina Palmieri Lynda E.Painting marcus J.Schultz LAmiNAR investigators Academic medical Center University of AmsterdamAmsterdamAZ 1105The Netherlands Department of Anaesthesia and Intensive Therapy medical University of Lublin Aleje Racklawickie 1–20-059 Lublin–Poland AZ JAN PALFIJN GENT Watersportlaan 5–9000 Gent–Belgium ABC medical School SaPauloBangúSP 5001Brazil Service d’Anesthésie Réanimation Chirurgicale Nantes 44093France University Hospital Carl Gustav Carus Dresden 01307Germany St James University Hospital Dublin D08 NHY1Ireland University of Genoa GenoaGE 16128Italy Linkoing University Hospital Linkoing 58185Sweden maasstad Hospital RotterdamDZ 3079The Netherlands Red Cross Hospital BeverwijkLE 1942The Netherlands martini Hospital GroningenNT 9728The Netherlands University of Texas medical Branch GalvestonTX 77555USA Turin CTO Burn Center TurinTO 10126Italy Rigshospitalet Copenhagen 2100Denmark La Paz University Hospital Madrid 28046Spain Ross Tilley Burn Centre Sunnybrook Health Sciences CentreToronto M4N 3M5Canada Royal Brisbane and Women’s Hospital Queensland UniversityHerstonQLD 4029Australia Australian and New Zealand Intensive Care Research Centre.monash University MelbourneVIC 3004Australia GH St-Louis-Lariboisière APHPParis 75010France BG Klinik Ludwigshafen Ludwigshafen 67071Germany Papanikoalou Hospital Thessaloniki 54621Greece middlemore Hospital OtahuhuAuckland 2025New Zealand Haukeland University Hospital Bergen 5021Norway Uppsala University Hospital Uppsala 75185Sweden Concord Repatriation General Hospital NSW University of SydneyConcord 2139Australia Ziekenhuis Netwerk Antwerpen-Stuivenberg Antwerpen 2060Belgium Universidade de Sao Paulo Sao Paulo 01246-903Brazil Universidade Estadual de Londrina Londrina 86057-970Brazil Sunnybrook Health Sciences Centre Toronto M4N 3M5Canada CHU Lyon St Luc Lyon 69007France CHU Nantes Service dánesthesie reanimation chirugicale Nantes 44093France Hopital Roger Salengro CHRU LilleLille 59037France Saint-Louis Hospital Paris 75010France BG University Hospital Bergmannsheil Bo

Background:It is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from *** study aimed to determine ventilation practices in burn intensive care units(ICUs)and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28(VFD-28).methods:This is an international prospective observational cohort study including adult burn patients requiring mechanical *** tidal volume(V_(T))was defined as V_(T)≤8 mL/kg predicted body weight(PBW).Levels of positive end-expiratory pressure(PEEP)and maximum airway pressures were *** association between V_(T) and VFD-28 was analyzed using a competing risk *** settings were presented for all patients,focusing on the first day of *** also compared ventilation settings between patients with and without inhalation ***:A total of 160 patients from 28 ICUs in 16 countries were *** V_(T) was used in 74%of patients,median V_(T) size was 7.3[interquartile range(IQR)6.2–8.3]mL/kg PBW and did not differ between patients with and without inhalation trauma(p=0.58).median VFD-28 was 17(IQR 0–26),without a difference between ventilation with low or high V_(T)(p=0.98).All patients were ventilated with PEEP levels≥5 cmH_(2)O;80%of patients had maximum airway pressuresmH_(2)***:In this international cohort study we found that lung-protective ventilation is used in the majority of burn patients,irrespective of the presence of inhalation *** of low V_(T) was not associated with a reduction in *** registration:*** *** of registration:9 December 2014.

关键词： mechanical ventilation Inhalation trauma Lung-protective Critical care

Venous thromboembolism prophylaxis practice and its association with outcomes in Australia and New Zealand burns patients

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Burns & Trauma 2021年第1期9卷 642-651页

作者： Lincoln m.Tracy Peter A.Cameron Yvonne Singer Arul Earnest Fiona Wood Heather Cleland Belinda J.Gabbe School of Public Health and Preventive medicine Monash University553 St Kilda RoadMelbourneVictoria3004Australia Emergency and Trauma Centre The Alfred HospitalCommercial RoadMelbourneVictoria3004Australia Victorian Adult Burns Service Alfred Hospital55 Commercial RoadMelbourneVictoria3004AustraliaAustralia Registry Sciences Unit Department of Epidemiology and Preventive MedicineMonash University553 St Kilda RoadMelbourneVictoria3004Australia Biostatistics Unit Department of Epidemiology and Preventive MedicineMonash University553 St Kilda RoadMelbourneVictoria3004Australia Burn Injury Research Unit University of Western Australia35 Stirling HighwayPerthWestern Australia6009Australia Health Data Research UK Swansea University Medical SchoolSwansea UniversitySingleton ParkSwanseaUK

Background:Patients with burn injuries are considered to have an increased risk of venous thromboembolism(VTE).While untreated VTEs can be fatal,no studies have examined chemoprophylaxis *** study aimed to quantify the variation in prevalence of VTE prophylaxis use in patients in Australian and New Zealand burns units and whether prophylaxis use is associated with in-hospital outcomes following burn ***:Admission data for adult burns patients(aged≥16 years)admitted between 1 July 2016 and 31 December 2018 were extracted from the Burns Registry of Australia and New *** effects logistic regression modelling investigated whether VTE prophylaxis usewas associated with the primary outcome of in-hospital ***:There were 5066 admissions over the study *** these patients,81%(n=3799)with a valid response to the VTE prophylaxis data field received some form of VTE *** of VTE prophylaxis ranged from 48.6%to 94.8%of patients between ***-hospital death was recorded inmortality(adjusted odds ratio=0.21;95%CI,0.07–0.63;p=0.006).Conclusions:Variation in the use of VTE prophylaxis was observed between the units,and prophylaxis use was associated with a decrease in the odds of *** findings provide an opportunity to engage with units to further explore differences in prophylaxis use and develop future best practice guidelines.

关键词： Burn injury Venous thromboembolism Prophylaxis Australia New Zealand

Fungal diversity notes 1036-1150:taxonomic and phylogenetic contributions on genera and species of fungal taxa

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Fungal Diversity 2019年第3期96卷 1-242页

作者： Kevin D.Hyde Danushka S.Tennakoon Rajesh Jeewon DJayarama Bhat Sajeewa S.N.maharachchikumbura Walter Rossi marco Leonardi Hyang Burm Lee Hye Yeon mun Jos Houbraken Thuong T.T.Nguyen Sun Jeong Jeon Jens Christian Frisvad Dhanushka N.Wanasinghe Robert Lucking Andre Aptroot marcela E.S.Caceres Samantha C.Karunarathna Sinang Hongsanan Rungtiwa Phookamsak Nimali Ide Silva Kasun m.Thambugala Ruvishika S.Jayawardena Indunil C.Senanayake Saranyaphat Boonmee Jie Chen Zong-Long Luo Chayanard Phukhamsakda Olinto L.Pereira Vanessa P.Abreu Andre Wilson Campos Rosado Buyck Bart Emile Randrianjohany Vale rie Hofstetter Tatiana B.Gibertoni Adriene mayrada Silva Soares Helio Longoni Plautz Jr helen maria Pontes Sotao William Kalhy Silva Xavier Jadson Diogo Pereira Bezerra Thays Gabrielle Linsde Oliveira Cristina mariade Souza-motta Oliane maria Correia magalhaes Digvijayini Bundhun Dulanjalee Harishchandra Ishara S.manawasinghe Wei Dong Sheng-Nan Zhang Dan-Feng Bao milan C.Samarakoon Dhandevi Pem Anuruddha Karunarathna Chuan-Gen Lin Jing Yang Rekhani H.Perera Vinit Kumar Shi-Ke Huang monika C.Dayarathne Anusha H.Ekanayaka Subashini C.Jayasiri Yuanpin Xiao Sirinapa Konta Tuula Niskanen Kare Liimatainen Yu-Cheng Dai Xiao-Hong Ji Xue-mei Tian Armin mesic Sanjay K.Singh Kunthida Phutthacharoen Lei Cai Touny Sorvongxay Vinodhini Thiyagaraja Chada Norphanphoun Napalai Chaiwan Yong-Zhong Lu Hong-Bo Jiang Jin-Feng Zhang Pranami D.Abeywickrama Janith V.S.Aluthmuhandiram Rashika S.Brahmanage ming Zeng Thilini Chethana Deping Wei martina Reblova Jacques Fournier Jana Nekvindova Renan do Nascimento Barbosa Jose Ewerton Felintodos Santos Neiva Tintide Oliveira Guo-Jie Li Damien Ertz Qiu-Ju Shang Alan J.L.Phillips Chang-Hsin Kuo Erio Camporesi Timur S.Bulgakov Saisamorn Lumyong E.B.Gareth Jones Putarak Chomnunti Eleni Gentekaki Frank Bungartz Xiang-Yu Zeng Sally Fryar Zdenko Tkalcec Junmin Liang Guangshuo Li Ting-Chi Wen Paras Nath Singh Yusufjon Gafforov Itthayakorn Promputtha Erandi Yasanthika Ishani D.Goonasekara Rui-Lin Zhao Qi Zhao Paul m Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanPeople’s Republic of China School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand East and Central Asia Regional Office World Agroforestry Centre(ICRAF)Kunming 650201YunnanPeople’s Republic of China Department of Biology Faculty of ScienceChiang Mai UniversityChiang Mai 50200Thailand mushroom Research Foundation 128 M.3 Ban Pa Deng T.Pa PaeA.Mae TaengChiang Mai 50150Thailand Department of Plant medicine National Chiayi University300 Syuefu RoadChiayi City 60004TaiwanPeople’s Republic of China Department of Health Sciences Faculty of ScienceUniversity of MauritiusReduitMauritius Formerly Department of Botany Goa UniversityGoaIndia No.128/1-J Azad Housing SocietyCurcaGoa Velha 403108India Department of Crop Sciences College of Agricultural and Marine SciencesSultan Qaboos UniversityPO Box 8123 Al KhoudOman Sect.Environmental Sciences Dept.MeSVAUniversity of L’Aquila67100 CoppitoAQItaly Division of Food Technology Biotechnology&AgrochemistryCollege of Agriculture&Life SciencesChonnam National UniversityGwangju 61186Korea Fungal Resources Research Division NNIBRSangju-si 37242Korea Westerdijk Fungal Biodiversity Institute Uppsalalaan 83584 CT UtrechtThe Netherlands Department of Biotechnology and Biomedicine DTUBioengineeringTechnical University of Denmark2800 Kongens LyngbyDenmark Botanischer Garten und Botanisches museum Berlin Freie Universitat BerlinKonigin-Luise-StraßBe 6-814195 BerlinGermany Laboratorio de Botanica/Liquenologia Instituto de BiocienciasUniversidade Federal de Mato Grosso do SulAvenida Costa e Silva s/nBairro UniversitarioCampo GrandeMatto Grosso do Sul CEP 79070-900Brazil Departamento de Biociencias Universidade Federal de SergipeItabaianaSergipe CEP:49500-000Brazil Shenzhen Key Laboratory of microbial

This article is the tenth series of the Fungal Diversity Notes,where 114 taxa distributed in three phyla,ten classes,30 orders and 53 families are described and *** described in the present study include one new family(*** in Dothideomycetes),five new genera(Caatingomyces,Cryptoschizotrema,Neoacladium,Paramassaria and Trochilispora)and 71 new species,(*** thailandica,Amniculicola aquatica,***,Angustimassarina sylvatica,Blackwellomyces lateris,Boubovia gelatinosa,Buellia viridula,Caatingomyces brasiliensis,Calophoma humuli,Camarosporidiella mori,Canalisporium dehongense,Cantharellus brunneopallidus,***,Castanediella meliponae,Coprinopsis psammophila,Cordyceps succavus,Cortinarius minusculus,***,Diaporthe italiana,***,Diatrypella delonicis,Dictyocheirospora aquadulcis,***,Digitodesmium chiangmaiense,Distoseptispora dehongensis,***,Dothiorella styphnolobii,Ellisembia aurea,Falciformispora aquatic,Fomitiporia carpinea,***,Grammothele aurantiaca,***,Hermatomyces bauhiniae,Jahnula queenslandica,Kamalomyces mangrovei,Lecidella yunnanensis,micarea squamulosa,muriphaeosphaeria angustifoliae,Neoacladium indicum,Neodidymelliopsis sambuci,Neosetophoma miscanthi,***,Nodulosphaeria aquilegiae,***,Paramassaria samaneae,Penicillium circulare,***,***-pumilae,***,***,Phaeoisaria siamensis,Phaeopoacea asparagicola,Phaeosphaeria penniseti,Plectocarpon galapagoense,Porina sorediata,Pseudoberkleasmium chiangmaiense,Pyrenochaetopsis sinensis,Rhizophydium koreanum,Russula prasina,Sporoschisma chiangraiense,Stigmatomyces chamaemyiae,***,***,***,***,Thysanorea uniseptata,Torula breviconidiophora,***,Trochilispora schefflerae and Vaginatispora palmae).Further,twelve new combinations(*** cryptotrema,Prolixandromyces australi,***,***,***,P.

关键词： 71 new taxa Ascomycota Basidiomycota Dothideomycetes Eurotiomycetes Lecanoromycetes Leotiomycetes Pezizomycetes Phylogeny Taxonomy

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作为一种实在论的批判的语境经验主义

哲学分析 2019年第1期10卷 17-37,196页

作者：彼特.穆尔塞普王一雪王幼军爱沙尼亚塔林理工大学上海师范大学哲学系

批判的语境经验主义将社会和规范方面融入对科学的理解中,实践实在论也使文化和规范方面在理解科学时发挥重要作用。对二者的比较分析表明,前者可作为实在论的一种形式。二者的结合可发展出"多元社会实在论"这一新的实在论形式。在讨论... 详细信息

批判的语境经验主义将社会和规范方面融入对科学的理解中,实践实在论也使文化和规范方面在理解科学时发挥重要作用。对二者的比较分析表明,前者可作为实在论的一种形式。二者的结合可发展出"多元社会实在论"这一新的实在论形式。在讨论了地图类比、目标导向的经验主义对不充分决定性问题的分析之后,通过借助海伦·朗基诺的最近研究可得出,多元社会实在论尽管可能,但由于缺乏上帝视角,它在为不充分决定性问题提供决定性解决方案时并不乐观。

关键词：目标导向的经验主义批判的语境经验主义实在论不充分决定性

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向心性肥胖与脑老化

世界核心医学期刊文摘(神经病学分册) 2006年第2期 10-11页

作者： Jagust W. Harvey D. mungas D. Haan m. 郭俊 helen Wills Neuroscience Institute 132 Barker Hall University of California Berkeley CA 94720 United States.Dr

Background: Central adiposity as an indicator of visceral fat is linked to vascular and metabolic factors that in turn are related to cognitive decline and dementia. Objective: To determine whether larger waist-hip ratio (WHR) is associated with structural brain changes that underlie cognitive decline and dementia. Design: Cross-sectional analysis of an epidemiologic cohort study of cognitive and functional decline (Sacramento Area Latino Study on Aging). Setting: Califor nia Central Valley. Participants: A total of 112 individuals selected from an on going cohort study of 1789 older Latino individuals. Baseline anthropomorphic me asures (WHR) and measurements of fasting blood glucose, cholesterol, and insulin levels and blood pressure were obtained. main Outcome measures: Baseline magnet ic resonance images were analyzed quantitatively to determine the hippocampal vo lumes in the right and left hemispheres and rated for the percentage of white ma tter hyperintensities. Results: Greater WHR (P=.02) and older age (P mpal volumes. The WHR and age were positively rel ated to white matter hyperintensities (P=.02 and P=.001, respectively). A 1-SD increase in WHR was associated with a 0.2-SD decrease in hippocampal volume and a 27%increase in white matter hyperintensities. These relationships were not a ffected by adjustment for body mass index, total cholesterol, fasting blood gluc ose, and insulin levels or systolic blood pressure in the models. Conclusion: A larger WHR may be related to neurodegenerative, vascular, or metabolic processes that affect brain structures underlying cognitive decline and dementia.

关键词：海马体积高信号白质髓质向心性肥胖认知功能

婴幼儿、儿童和青少年终末期医疗照护：NICE指南概要

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英国医学杂志中文版 2017年第11期20卷 629-632页

作者： Gemma Villanueva m Stephen murphy David Vickers Emily Harrop Katharina Dworzynski 孙婧束永前 National Guideline Alliance Royal College of Gynaecologists and ObstetriciansLondon NW1 4RGUK Cambridgeshire Community Services NHS Trust St Ives PE27 4LG UK East Anglia'sChildren's Hospices Milton CB24 6DF UK helen & DouglasHouse Oxford OX41RW UK Oxford UniversityHospitals OxfordOX3 9DU UK 江苏省肿瘤医院肿瘤科

儿童和青少年会有多种临终状态，有时可能许多年生活在这种状态下。本指南建议，终末期医疗照护（又称为临终关怀或姑息治疗）应作为一个长期行动，在被诊断为已无多日时开始，并为未来规划。有时可能要在孩子出生前就开始规划。

关键词：婴幼儿儿童医疗照护发展现状

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兆伏级锥形束CT在自适应性放疗中的应用

中国癌症杂志 2006年第9期16卷 763-764页

作者： O.morin m. Aubin J. Chen H. Chen J - F. Aubry A. Gillis K. Bucci m. Geffen K. Kelly H.Chen L.Simpson J.Pouliot 王艳阳（译）陆嘉德（校） UCSF Comprehensive Cancer Center San Francsico California CA-94143. Savannah Oncology Center Savannah GA-31406 Christiana Care Health Services Helen F Graham Cancer Center Newark DE 19713 复旦大学附属肿瘤医院放疗科新加坡国立肿瘤中心

随着兆伏级锥形束CT(megavoltageCone-BeamCT,mVCBCT)技术的诞生,目前利用电子验证影像设备(electronicportalimagingdevices,EPID)与治疗用X线束在治疗体位状态下对患者进行三维成像,并根据所获影像进行电子密度校准,已逐渐在临床上获... 详细信息

随着兆伏级锥形束CT(megavoltageCone-BeamCT,mVCBCT)技术的诞生,目前利用电子验证影像设备(electronicportalimagingdevices,EPID)与治疗用X线束在治疗体位状态下对患者进行三维成像,并根据所获影像进行电子密度校准,已逐渐在临床上获得应用。本文首先介绍mVCBCT的一般特性,并对其在适应性放疗(AdaptiveRadiationTherapy,ART)中的临床应用及发展方向进行探讨。

关键词：计算机断层摄影术 X线放射治疗体位体重放射治疗剂量

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阿梅格尔巴克/哥本山

城市环境设计 2019年第2期 172-183页

作者： Nanna Gyldholm m?ller Alberto Cumerlato Aleksander Wadas Alexander Codda Alexander Ejsing Alexandra Gustafsson Alina Tamosiunaite Armor Gutierrez Anders Hjortn?s Andreas Klok Pedersen Annette Jensen Ariel Wallner Ask Andersen Balaj IIulian Blake Smith Borko Nikolic Brygida Zawadzka Buster Christensen Chris Falla Chris Zhongtian Yuan Daniel Selensky Dennis Rasmussen Espen Vik Finn N?rkj?r Franck Fdida Gonzalo Castro Gül Ertekin George Abraham helen Chen Henrick Poulsen Henrik R?mer Kania Horia Spirescu Jakob Ohm Laursen Jelena Vucic Jeppe Ecklon Ji-young Yoon Jing Xu Joanna Jakubowska Johanna Nenander Kamilla Heskje Katarzyna Siedlecka Krzysztof marciszewski Laura W?tte Liang Wang Lise Jessen Long Zuo maciej Zawadzki mads Enggaard Stidsen marcelina Kolasinska marcos Bano maren Allen mathias Bank matti N?rgaard michael Andersen Narisara Ladawal Schr?der Niklas A. Rasch Nynne madsen ?ssur Nols? Pero Vukovic Richard Howis Ryohei Koike Se Hyeon Kim Simon masson Sunming Lee Toni mateu Xing Xiong Zoltan David Kalaszi Rasmus Hjortshoj 陈子钰

垃圾焚烧发电厂阿梅格尔巴克/哥本山位于工业区,多年来,该工业区已成为冒险者们的极限运动目的地。原始的工业设施为各种极限运动活动提供了场所,如缆绳滑水、卡丁车和攀岩等。阿梅格尔巴克/哥本山是该地区最重要的地标,其建筑亟须更新... 详细信息

垃圾焚烧发电厂阿梅格尔巴克/哥本山位于工业区,多年来,该工业区已成为冒险者们的极限运动目的地。原始的工业设施为各种极限运动活动提供了场所,如缆绳滑水、卡丁车和攀岩等。阿梅格尔巴克/哥本山是该地区最重要的地标,其建筑亟须更新。我们提出了一种新型的垃圾焚烧发电厂,这种工厂能产生经济、环保和社会效益。我们不将阿梅格尔巴克/哥本山视为一个孤立的对象,而是调动起建筑的

关键词：巴克本山

Catheter ablation for atrial fibrillation in a subset of patients with concomitant hypertension

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World Journal of Hypertension 2015年第2期5卷 98-103页

作者： Tushar Sharma Benjamin J Scherlag Hiroshi Nakagawa Warren m Jackman Ralph Lazzara Sunny S Po Heart Rhythm Institute at the University of Oklahoma Health Sciences Center Oklahoma CityOK 73104United States

AIm:To study patients with atrial fibrillation and hypertension who had successful catheter ablation for changes in blood pressure 1 year ***:A retrospective study was performed on patients who had catheter ablation for atrial fibrillation(AF) and hypertension(HTN) which included local autonomic ganglionated plexi denervation and pulmonary veins *** the records of 119 patients,followup data was found in order to determine the presence of sinus rhythm and data on systolic(SBP) and diastolic blood pressure at 2 wk,3 mo,6 mo and 1 year after the ablation *** echocardiograms were taken at the time of the catheter procedure to determine left atrial dimensions(LADs) and left ventricular ***:There was no significant difference in the preablation mean blood pressures between the two groups(P = 0.08).After 1 year 33 of the 60 with AF and HTN were in sinus rhythm,of whom 12 had normal LADs,≤ 4 cm Group 1,and 21 had enlarged left atria(LADs > 4 cm,Group 2).For Group 1,at 1 year of follow up,there was a significant difference in the SBP(119.2 ± 13 mm Hg) compared to pre-ablation(142.6 ± 13.7 mm Hg,P = 0.001).For Group 2,there was no significant difference in the SBP,pre-ablation(130.3 ± 17.5 mm Hg) and at 1 year of follow up(130.4 ± 13.4 mm Hg,P = 0.75).All patients were on similar anti-hypertensive *** was a trend for a greater left ventricular size in Group 2 compared to Group ***:We suggest that Group 1 had HTN due to sympathetic hyperactivity,neurogenic HTN;whereas HTN in Group 2 was based on arterial vasoconstriction.

关键词： Atrial fibrillation Hypertension Autonomic nervous system Catheter ablation