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Continuity of care by a primary midwife(caseload midwifery):a cost analysis using results from the CoSMoS randomised controlled trial

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Gynecology and obstetrics Clinical Medicine 2024年第2期4卷 94-101页

作者： Emily J Callander Hannah Jackson helen.L McLachlan Mary-Ann Davey Della A Forster University of Technology Sydney SydneyNew South WalesAustralia The Royal Women's Hospital MelbourneVictoriaAustralia Faculty of Health University of Technology SydneyBroadwayNew South WalesAustralia Judith Lumley Centre La Trobe UniversityMelbourneVictoriaAustralia School of nursing and Midwifery a Trobe UniversityMelbourneVictoriaAustralia Department of obstetrics and Gynaecology Monash UniversityClaytonVictoriaAustralia

Introduction Caseload midwifery(continuity of midwifery carer)offers benefits including lower caesarean section rates,lower risks of preterm birth and stilbirth,and improved maternal satisfaction of *** these advantages,concerns about additional costs hinder widespread *** study examinesthecost of caseload midwifery compared with standard maternity care from the perspective of both public hospitals and public *** A cost analysis was conducted using data from a randomised controlled trial of 2314 low-risk pregnant women in Melbourne,*** randomised to caseload care received antenatal,intrapartum and postpartum care from a primary midwife,with some care provided by a‘back-up'*** in standard care received midwifery-led care with varying levels of continuity,junior obstetric care or community-based medical *** cost analysis compared differences in mean costs of health resources to public hospitals and to public ***,a budget impact analysis estimated total costs to the health system between 2023 and *** For public hospitals,there was no significant difference in overall costs between women receiving caseload midwifery(n=1146)versus standard care(n=1151)($SA12363(SD:$A4967)vs$A12323(SD:$A7404);p=0.85).Conversely,public funders incurred lower expenditures for women receiving caseload midwifery($A20330(SD:$A8312))versus standard care($A21637(SD:$A11818);pnalysis estimated savings of sA625million to the health system over the next 5 years with expanded access to caseloadmidwifery *** Caseloadmidwifery in low-risk women is cost-neutral to public hospitals and cost-saving to public *** abstract Continuity of midwifery for low-risk women reduces costs to public funders,with no additional costs to hospitals.

关键词： random continuity Continuity

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客舱内饰的不断发展

航空维修与工程 2024年第7期 25-26页

作者： helen.Massy 赵平(编译) 不详

随着疫情后航空业的复苏,旅客和航空公司对客舱内饰的改进需求日益凸显,如何在提升旅客体验的同时减少碳排放,已成为航空业客舱设备专家面临的一个持续挑战。航空业内的航空公司、飞机制造商、客舱设备供应商、客舱改装咨询公司等都在... 详细信息

随着疫情后航空业的复苏,旅客和航空公司对客舱内饰的改进需求日益凸显,如何在提升旅客体验的同时减少碳排放,已成为航空业客舱设备专家面临的一个持续挑战。航空业内的航空公司、飞机制造商、客舱设备供应商、客舱改装咨询公司等都在大力推进客舱内饰的改进。

关键词：航空公司飞机制造商航空业旅客体验设备供应商大力推进客舱减少碳排放

Delineation of a novel dendritic-like subset in human spleen

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Cellular & Molecular Immunology 2016年第4期13卷 443-450页

作者： Sawang Petvises Dipti Talaulikar helen.C o'neill Research School of Biology The Australian National University Canberra Australia John Curtin School of Medical Research The Australian National University Canberra Australia AnU Medical School College of Medicine Biology and Environment The Australian National University Canberra Australia Department of Haematology Canberra Hospital Canberra Australia

Dendritic cells （DCs） and monocyte subpopulations present in the human spleen were analyzed by flow cytometry in an attempt to identify the presence of a novel dendritic-like cell subset described previously in mice and named L-DCs. In this study, an equivalent of this novel murine subset was characterized in the human spleen, thus increasing our knowledge of the antigen-presenting cell types present in the human spleen. Human L-DCs were identified as a hCD11c^hCD11b＋HLA-DR-hCD86＋ subset in the spleen, along with the previously described subsets of hCDlc＋ DCs, hCD123＋ plasmacytoid DCs （pDCs）, hCD16＋ DCs and hCD141＋ DCs. Three subsets of monocytes were also characterized. DC and monocyte subsets in human spleen had phenotypes similar to those of subsets in human blood. In line with murine studies, the presence of L-DC progenitors within the spleen was also investigated. When human splenocytes depleted of T and B cells were cocultured with the murine stromal line 5G3, hematopoiesis ensued and hCD11c＋HLA-DR＋ and hCD11c＋HLA-DR- cells were produced. The latter resemble L-DCs, which are also produced in murine spleen cocultures. Both subsets expressed hCDSo and hCD86, which identifies them as antigen-presenting cells, particularly DCs, and were highly endocytic. It is noteworthy that murine splenic stroma can serve as a support matrix for human hematopoiesis and DC production. These results support the hypothesis that 5G3 must express both cell-associated and soluble factors that can signal hematopoiesis in human and murine progenitors.

关键词： dendritic cells myelopoiesis spleen stroma

Combination therapy for male erectile dysfunction and urinary incontinence

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Asian Journal of Andrology 2008年第1期10卷 149-154页

作者： helen.Zafirakis Run Wang o. Lenaine Westney Division of Urology University of Texas Health Science Center at Houston Houston TX 77030 USA Department of Urology MD Anderson Cancer Center Houston TX 77030 USA

Urinary incontinence （UI） and erectile dysfunction （ED） are both very prevalent conditions. Insertion of an artificial urinary sphincter （AUS） and penile prosthesis （PP） is an effective and proven method of treatment for both conditions. With advancing age, as well as with increasing populations of patients radically treated for prostate cancer, the occurrence of both conditions found in the same patient is increasing. The purpose of this article was to analyze the available evidence for simultaneous surgical management of male ED and UI using prosthetic devices. The existing literature pertaining to dual implantation of AUS and PP was reviewed. The concomitant insertion of the PP with the male perineal sling was also considered. Concurrent ED and UI are increasingly seen in the post radical prostatectomy population, who are often younger and less willing to suffer with these conditions. Insertion of an AUS and PP, either simultaneously or as a two-stage procedure, appears to be a safe, efficacious and long-lasting method of treatment. The improvements in design of both the AUS and PP as well as the development of the single transverse scrotal incision have made simultaneous insertion of these prostheses possible. Dual implantation of the PP and male sling looks promising in a selected population. In conclusion, the insertion of the AUS and PP for the treatment of concurrent UI and ED is safe and effective. Simultaneous insertion of these prostheses in the same patient offers potential advantages in operative and recovery time and is associated with high patient satisfaction. Combination therapy should therefore be included in the arsenal of treatment of these conditions.

关键词： urinary incontinence erectile dysfunction impotence penile prosthesis artificial urinary sphincter male sling

Adult neural stem cell therapy for the brain

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Adult neural stem cell therapy for the brain

“文化活化”视域下高校图书馆古籍活化实践路径探索--以浙江大学图书馆馆藏拓片活化为例

中国神经科学学会第六届学术会议暨学会成立十周年庆祝大会

作者： helen. L. Zhang Department of Genetics.Harvard Medical School Boston M.A 02215USA

＜正＞neural stem cells （nSCs） are present not only in the developing nervous systems, but also in the adult human central nervous system （CnS）. It is long thought that the subventricular zone of the lateral ventricles and the dentate gyrus of the hippocampus are the main sources of human adult nSCs, which are considered to be a reservoir of new neural cells. Recently adult nSCs with potential neural capacity have been isolated from white matter and inferior prefrontal subcortex in the human brain. Rapid advances in the stem cell biology have raised appealing possibilities of replacing damaged or lost neural cells by transplantation of in vitro-expanded stem cells and/or their neuronal progeny. However, sources of stem

关键词： neural stem cell therapy brain

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大学图书馆学报 2024年第1期42卷 100-106页

作者：薛霏韩松涛黄晨浙江大学图书馆浙江杭州310058

在“文化强国”建设的背景下,古籍活化成为古籍保护与利用工作中的重要任务。文章提出了一种新的以文化活化促进古籍活化的特藏揭示模式,并以浙江大学图书馆拓片活化应用实践为例,总结了高校图书馆古籍活化的五种实践路径及“4C”策略,... 详细信息

在“文化强国”建设的背景下,古籍活化成为古籍保护与利用工作中的重要任务。文章提出了一种新的以文化活化促进古籍活化的特藏揭示模式,并以浙江大学图书馆拓片活化应用实践为例,总结了高校图书馆古籍活化的五种实践路径及“4C”策略,以期为古籍活化工作提供新思路。

关键词：文化活化古籍活化拓片高校图书馆图书馆实践

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景观—社会学视角下的北京高密度城区儿童游戏专属和发现空间

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风景园林 2024年第2期31卷 19-31页

作者： [英]海伦·伍利汤湃谢菲尔德大学风景园林系英国皇家风景园林协会 GUIC国际研究组中国研究组同济大学建筑与城市规划学院 GUIC国际研究组

【目的】在任何地方进行游戏是儿童的天性。以北京中心城区高密度城市环境为例,深入探究儿童如何创造性地使用城市户外公共空间。【方法】从景观—社会学视角,通过半构建访谈、照片访谈和行为观察等方法收集儿童户外活动空间数据。【结... 详细信息

【目的】在任何地方进行游戏是儿童的天性。以北京中心城区高密度城市环境为例,深入探究儿童如何创造性地使用城市户外公共空间。【方法】从景观—社会学视角,通过半构建访谈、照片访谈和行为观察等方法收集儿童户外活动空间数据。【结果】将儿童使用的多样户外空间分为专属空间和发现空间,以及介于两者之间的灵活空间3种类别。深入探究不同类别的活动空间的特点发现,配置有固定游戏设备的儿童专属游乐场所提供的游戏机会单一,无法满足全龄儿童进行多样户外游戏的需求,但专属空间为儿童提供了最为正式且相对安全的游戏环境;儿童广泛使用的灵活空间,如广场和可进入的绿地,其开放性为更为广泛的年龄群体提供了可供奔跑、跳跃和骑车等高强度活动的机会,但营造公平且友好的共享公共环境是灵活空间面临的挑战;发现空间的设计初衷并非为儿童使用,因此儿童在使用这类空间的过程中普遍存在潜在安全隐患。【结论】针对高密度城市环境中有限的公共空间提出了更加包容且儿童友好的营造方式以及优化设计建议,期望为提升高密度城市公共空间服务效能、实现城市可持续发展提供一定科学参考。

关键词：高密度城区儿童友好可供性发现空间户外空间

Velocity variation of internal shock waves in gamma ray bursts: observational properties

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Science China(Physics,Mechanics & Astronomy) 2006年第4期49卷 505-512页

作者： Poon helen Astronomy Department Beijing Normal University

The work uses the data in the TTS mode of BATSE to analyze the time lags and pulse widths of GRB960113 and GRB960722 in high as well as low energy bands. The results show that their time lags increase monotonously. This phenomenon can reasonably be interpreted with the model of internal shock waves of γ-ray bursts (GRB). Perhaps we obtain the direct observational evidence for the fireball model of GRBs for the first time.

关键词： GRB, time lag, shock wave.

Record of Early Tonian mafic magmatism in the central Espinhaco(Brazil):new insights for break-up of the neoproterozoic landmass ancestor of Sao Francisco-Congo paleocontinent

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Geoscience Frontiers 2020年第6期11卷 2323-2337页

作者： helen.F.Moreira AndréDanderfer Alice F.o.Costa Samuel M.Bersan Cristiano C.Lana Gláucia n.Queiroga Post Graduate Program of Department of Geology Mine SchoolFederal University of Ouro PretoBrazil Department of Geology Mine SchoolFederal University of Ouro PretoBrazil

Petrological characterization,U-Pb geochronology,Lu-Hf analyses and major and trace element data from mafic intrusions in the Central Espinhaco(central portion of the Brazilian shield)are used here to investigate the geological significance of the Early neoproterozoic magmatism in the context of the Sao Francisco-Congo *** mafic bodies are represented by medium to coarse-grained metagabbros with plagioclase,amphibole and *** U-Pb isotopic data from two samples yielded weighted mean 206pb/238U ages of 895±3.4 Ma(MSWD=1.7)and 896±2.4 Ma(MSWD=0.64),regarded as the best estimates for the crystallization age of these mafic *** and trace element data(including REEs)show that the gabbros originated from a subalkaline tholeiitic magma,typical of intraplate *** rocks are slightly enriched in LREEs and LILEs and depleted in *** new isotope and geochemical data,along with regional knowledge,indicate that these metagabbros mark the beginning of an important Tonian-age extensional tectonic event of the landmass of which the Sao Francisco-Congo paleocontinent was part(Rodinia supercontinent or Central African block?).We furthermore suggest that these rocks belong to a prominent suite of Tonian-age mafic rocks that mark a diachronic breakup attempt of this landmass which may have occurred from south to north along the Espinhaco mountain range.

关键词： Mafic rocks Espinhaco basin Sao Francisco-Congo paleocontinent Tonian rifting U–Pb geochronology