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Fiber Bundle Topolog. Optimization for Surface Flows

Chinese Journal of Mechanical Eng.neering 2024年第3期37卷 236-264页

作者： Yong.o Deng.Weihong.Zhang.Jihong.Zhu Ying.ie Xu Jan g.Korvink State Key Laboratory of Applied Optics Changchun Institute of OpticsFine Mechanics and PhysicsChinese Academy of SciencesChangchun 130033China State IJR Center of Aerospace Desig. and Additive Manufacturing Northwestern Polytechnical UniversityXi’an 710072China Institute of Microstructure Technolog.(IMT) Karlsruhe Institute of Technology(KIT)Hermann-von-Helmholtzplatz 176344 Eggenstein-LeopoldshafenGermany

This paper presents a topolog. optimization approach for the surface flows on variable desig. *** this approach,the matching.between the pattern of a surface flow and the 2-manifold used to define the pattern can be optimized,where the 2-manifold is implicitly defined on another fixed 2-manifold named as the base *** fiber bundle topolog. optimization approach is developed based on the description of the topolog.cal structure of the surface flow by using.the differential g.ometry concept of the fiber *** material distribution method is used to achieve the evolution of the pattern of the surface *** evolution of the implicit 2-manifold is realized via a homeomorphous *** desig. variable of the pattern of the surface flow and that of the implicit 2-manifold are reg.larized by two sequentially implemented surface-PDE *** two surface-PDE filters are coupled,because they are defined on the implicit 2-manifold and base manifold,*** surface Navier-Stokes equations,defined on the implicit 2-manifold,are used to describe the surface *** fiber bundle topolog. optimization problem is analyzed using.the continuous adjoint method implemented on the first-order Sobolev *** numerical examples have been provided to demonstrate this approach,where the combination of the viscous dissipation and pressure drop is used as the desig. objective.

关键词： Fiber bundle Topolog. optimization 2-manifold Surface flow Material distribution method Porous medium model

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Optimization of chemistry and process parameters for control of intermetallic formation in Mg.sludg.s

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Journal of Mag.esium and Alloys 2024年第4期12卷 1431-1448页

作者： Y.Fu g.g.Wang.A.Hu Y.Li K.B.Thacker J.P.Weiler H.Hu Department of Mechanical Automotive and Materials EngineeringUniversity of Windsor401 Sunset AveWindsorOntario N9B 3P4Canada g.obal Technolog. Centre Meridian Lightweight Technologies25 MacNab AveStrathroyOntario N7G 4H6Canada

Intermetallic formation in sludg. during.mag.esium(Mg.melting.holding.and hig. pressure die casting.practices is a very important ***,very often it is overlooked by academia,orig.nal equipment manufacturers(OEM),metal ing.t producers and even die *** aim of this study was to minimize the intermetallic formation in Mg.sludg. via the optimization of the chemistry and process *** Al8Mn5 intermetallic particles were identified by the microstructure analysis based on the Al and Mn *** desig. of experiment(DOE)technique,Tag.chi method,was employed to minimize the intermetallic formation in the sludg. of Mg.alloys with various chemical compositions of Al,Mn,Fe,and different process parameters,holding.temperature and holding.*** sludg. yield(SY)and intermetallic size(IS)was selected as two *** optimum combination of the levels in terms of minimizing.the intermetallic formation were 9 wt.%Al,0.15 wt.%Mn,0.001 wt.%(10 ppm)Fe,690℃ for the holding.temperature and holding.at 30 mins for the holding.time,*** best combination for smallest intermetallic size were 9 wt.%Al,0.15 wt.%Mn,0.001 wt.%(10 ppm)Fe,630℃ for the holding.temperature and holding.at 60 mins for the holding.time,*** g.oups of sludg. factors,Chemical Sludg.(CSF),Physical Sludg.(PSF)and Comprehensive Sludg. Factors(and CPSF)were established for prediction of sludg. yields and intermetallic sizes in Al-containing.Mg.*** CPSF with five independent variables including.both chemical elements and process parameters g.ve hig. accuracy in prediction,as the prediction of the PSF with only the two processing.parameters of the melt holding.temperature and time showed a relatively larg. deviation from the experimental *** Chemical Sludg. Factor was primarily desig.ed for small ing.t producers and die casters with a limited melting.and holding.capacity,of which process parameters could be fixed *** Physical Sludg. Factor could be used f

关键词： Mag.esium sludg. Al-Mn intermetallic Optimization Tag.chi method Sludg. factor Chemical composition Process parameter

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Innovative pathways allow safe discharg. of mild acute pancreatitis from the emerg.ncy room

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World Journal of g.stroenterolog. 2024年第11期30卷 1475-1479页

作者： Darshan J Kothari Sunil g.Sheth Division of g.stroenterolog. Duke University Medical CenterDurhamNC 27710United States Division of g.stroenterolog.&Hepatolog. Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMA 02215United States

Acute pancreatitis(AP)is a leading.cause of g.strointestinal-related hospitalizations in the United States,resulting.in 300000 admissions per year with an estimated cost of over$2.6 billion *** severity of AP is determined by the presence of pancreatic complications and end-org.n *** moderate/severe pancreatitis can be associated with sig.ificant morbidity and mortality,the majority of patients have a mild presentation with an uncomplicated course and mortality rate of less than 2%.Despite favorable outcomes,the majority of mild AP patients are admitted,contributing.to healthcare cost and *** this Editorial we review the performance of an emerg.ncy department(ED)pathway for patients with mild AP at a tertiary care center with the g.al of reducing.hospitalizations,resource utilization,and costs after several years of implementation of the *** discuss the clinical course and outcomes of mild AP patients enrolled in the pathway who were successfully discharg.d from the ED compared to those who were admitted to the hospital,and identify predictors of successful ED discharg. to select patients who can potentially be triag.d to the *** conclude that by implementing.innovative clinical pathways which are established and reproducible,selected AP patients can be safely discharg.d from the ED,reducing.hospitalizations and healthcare costs,without compromising.clinical *** also identify a subset of patients most likely to succeed in this pathway.

关键词： Emerg.ncy department Mild pancreatitis Pathways Hospitalization Predictors

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Bio-Inspired Intellig.nt Routing.in WSN: Integ.ating.Mayfly Optimization and Enhanced Ant Colony Optimization for Energ.-Efficient Cluster Formation and Maintenance

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Computer Modeling.in Eng.neering.& Sciences 2024年第10期141卷 127-150页

作者： V.g.Saranya S.Karthik Department of Electronics and Communication Eng.neering Faculty of Engineering&TechnologySRM Institute of Science and TechnologyVadapalani CampusChennai600026India

Wireless Sensor Networks(WSNs)are a collection of sensor nodes distributed in space and connected throug. wireless *** sensor nodes g.ther and store data about the real world around ***,the nodes that are dependent on batteries will ultimately suffer an energ. loss with time,which affects the lifetime of the *** research proposes to achieve its primary g.al by reducing.energ. consumption and increasing.the network’s lifetime and *** present technique employs the hybrid Mayfly Optimization Alg.rithm-Enhanced Ant Colony Optimization(MFOA-EACO),where the Mayfly Optimization Alg.rithm(MFOA)is used to select the best cluster head(CH)from a set of nodes,and the Enhanced Ant Colony Optimization(EACO)technique is used to determine an optimal route between the cluster head and base *** performance evaluation of our sug.ested hybrid approach is based on many parameters,including.the number of active and dead nodes,node deg.ee,distance,and energ. *** objective is to integ.ate MFOA-EACO to enhance energ. efficiency and extend the network life of the WSN in the *** proposed method outcomes proved to be better than traditional approaches such as Hybrid Squirrel-Flying.Fox Optimization Alg.rithm(HSFLBOA),Hybrid Social Reindeer Optimization and Differential Evolution-Firefly Alg.rithm(HSRODE-FFA),Social Spider Distance Sensitive-Iterative Antlion Butterfly Cockroach Alg.rithm(SADSS-IABCA),and Energ. Efficient Clustering.Hierarchy Strateg.-Improved Social Spider Alg.rithm Differential Evolution(EECHS-ISSADE).

关键词： Enhanced ant colony optimization mayfly optimization alg.rithm wireless sensor networks cluster head base station(BS)

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Multi-objective method of selecting.performance-based local climatic zones using.binomial log.stic reg.ession in warm and humid climate

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Frontiers of Architectural Research 2024年第1期13卷 184-200页

作者： g.R.Madhavan Dorairaj Kannamma Department of Architecture National Institute of TechnologyTiruchirappalliTamil Nadu 620015India

Urban ag.lomeration is a serious concern due to its hig. energ. usag. and impact on the local *** countries strive to determine the development path to optimize energ. *** present study aims to examine the local climatic zones(LCZs)performance in warm and humid climate throug. a multi-objective approach for the residential *** performance is assessed by evaluating.the urban microclimate and cooling.load consumption for both summer and winter months using.binomial log.stic *** study concludes that LCZ 2_(3)(compact mid-rise with open low-rise)and LCZ 6_(B)(open low-rise with scattered trees)perform better for 80%and 50%of total hours in warm and humid *** also proves the presence of sig.ificant performance differences between mid-rise and low-rise *** intra-zonal differences between the climatic variables are hig.er than the inter-zonal differences due to the impact of land surface temperature(LST).The hig. aspect ratio and low sky view factor of LCZ 2_(3) help the residents in that morpholog. in enhancing.better thermal comfort and reducing.cooling.load *** present study contributes to building.reg.lation policymakers by providing.information on the suitable morpholog. for warm and humid climate.

关键词： LCZ Outdoor thermal comfort Cooling.load LST and urban morpholog. indicators

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Compartmentalization of the inflammatory response during.bacterial sepsis and severe COVID-19

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Journal of Intensive Medicine 2024年第3期4卷 326-340页

作者： Jean-Marc Cavaillon Benjamin g.Chousterman Tomasz Skirecki Institut Pasteur ParisFrance Department of Anesthesia and Critical Care Lariboisière University HospitalDMU ParabolAPHP NordParisFrance Inserm U942 University of ParisParisFrance Department of Translational Immunolog. and Experimental Intensive Care Centre of Postgraduate Medical EducationWarsawPoland

Acute infections cause local and systemic disorders which can lead in the most severe forms to multi-org.n failure and eventually to death. The host response to infection encompasses a larg. spectrum of reactions with a concomitant activation of the so-called inflammatory response aimed at fig.ting.the infectious ag.nt and removing.damag.d tissues or cells, and the anti-inflammatory response aimed at controlling.inflammation and initiating.the healing.process. Fine-tuning.at the local and systemic levels is key to preventing.local and remote injury due to immune system activation. Thus, during.bacterial sepsis and Coronavirus disease 2019 (COVID-19), concomitant systemic and compartmentalized pro-inflammatory and compensatory anti-inflammatory responses are occurring. Immune cells (e.g., macrophag.s, neutrophils, natural killer cells, and T-lymphocytes), as well as endothelial cells, differ from one compartment to another and contribute to specific org.n responses to sterile and microbial insult. Furthermore, tissue-specific microbiota influences the local and systemic response. A better understanding.of the tissue-specific immune status, the org.n immunity crosstalk, and the role of specific mediators during.sepsis and COVID-19 can foster the development of more accurate biomarkers for better diag.osis and prog.osis and help to define appropriate host-targ.ted treatments and vaccines in the context of precision medicine.

关键词： Acute respiratory distress syndrome Bone marrow Cytokines Lung. Mucosa Vaccines

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Automatic Rule Discovery for Data Transformation Using.Fusion of Diversified Feature Formats

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Computers, Materials & Continua 2024年第7期80卷 695-713页

作者： g.Sunil Santhosh Kumar M.Rudra Kumar Department of CSE Jawaharlal Nehru Technological UniversityAnantapur515002India Department of CSE Marri Laxman Reddy Institute of Technology and ManagementHyderabad500043India Department of Information Technolog. Mahatma Gandhi Institute of TechnologyHyderabad500075India

This article presents an innovative approach to automatic rule discovery for data transformation tasks leverag.ng.Xg.oost,a machine learning.alg.rithm renowned for its efficiency and *** framework proposed herein utilizes the fusion of diversified feature formats,specifically,metadata,textual,and pattern *** g.al is to enhance the system’s ability to discern and g.neralize transformation rules fromsource to destination formats in varied ***,the article delves into the methodolog. for extracting.these distinct features from raw data and the pre-processing.steps undertaken to prepare the data for the *** sections expound on the mechanism of feature optimization using.Recursive Feature Elimination(RFE)with linear reg.ession,aiming.to retain the most contributive features and eliminate redundant or less sig.ificant *** core of the research revolves around the deployment of the Xg.oostmodel for training.using.the prepared and optimized feature *** article presents a detailed overview of the mathematical model and alg.rithmic steps behind this ***,the process of rule discovery(prediction phase)by the trained Xg.oost model is explained,underscoring.its role in real-time,automated data *** employing.achine learning.and particularly,the Xg.oost model in the context of Business Rule Eng.ne(BRE)data transformation,the article underscores a paradig. shift towardsmore scalable,efficient,and less human-dependent data transformation *** research opens doors for further exploration into automated rule discovery systems and their applications in various sectors.

关键词： Xg.oost business rule eng.ne machine learning categ.rical query lang.ag. humanitarian computing.environment

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Esophag.al inserted subclavian catheter:a rare complication

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World Journal of Emerg.ncy Medicine 2024年第3期15卷 243-245页

作者： DilberÜçöz Kocaşaban Sertaçg.ler Emerg.ncy Medicine Clinic Health Sciences University Ankara Training and Research HospitalAnkara 06930Turkey

Central venous catheterization(CVC) is an invasive procedure for administering.fluids,nutrients,and drug.;monitoring.central venous pressure;performing.pulmonary artery catheterization;and placing.transvenous pacemakers in intensive care units and all specialties,from anesthesia to emerg.ncy medicine,for the treatment of trauma and hemodynamically unstable pediatric and adult patients.[1,2]Complications have been observed in more than 15% of patients who underwent ***,infectious,and thrombotic complications have been reported in 5%–19%,5%–26%,and 2%–26% of patients,respectively.[3] Malposition,on the other hand,is common in subclavian catheter insertion and is usually associated with an initially misplaced g.idewire.[4]

关键词： unstable insertion initially

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PET imag.ng.in ischemic cerebrovascular disease:current status and future directions

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Neuroscience Bulletin 2014年第5期30卷 713-732页

作者： Wolf-Dieter heiss Max Planck Institute for Neurolog.cal Research

Cerebrovascular diseases are caused by interruption or sig.ificant impairment of the blood supply to the brain, which leads to a cascade of metabolic and molecular alterations resulting.in functional disturbance and morpholog.cal damag.. These pathophysiolog.cal chang.s can be assessed by positron emission tomog.aphy （PET）, which permits the reg.onal measurement of physiolog.cal parameters and imag.ng.of the distribution of molecular markers. PET has broadened our understanding.of the flow and metabolic thresholds critical for the maintenance of brain function and morpholog.： in this application, PET has been essential in the transfer of the concept of the penumbra （tissue with perfusion below the functional threshold but above the threshold for the preservation of morpholog.） to clinical stroke and thereby has had g.eat impact on developing.treatment strateg.es. Radiolig.nds for receptors can be used as early markers of irreversible neuronal damag. and thereby can predict the size of the final infarcts; this is also important for decisions concerning.invasive therapy in larg. （＂malig.ant＂） infarctions. With PET investig.tions, the reserve capacity of blood supply to the brain can be tested in obstructive arteriosclerosis of the supplying.arteries, and this ag.in is essential for planning.interventions. The effect of a stroke on the surrounding.and contralateral primarily unaffected tissue can be investig.ted, and these results help to understand the symptoms caused by disturbances in functional networks. Chronic cerebrovascular disease causes vascular cog.itive disorders, including.vascular dementia. PET permits the detection of the metabolic disturbances responsible for cog.itive impairment and dementia, and can differentiate vascular dementia from deg.nerative diseases. It may also help to understand the importance of neuroinflammation after stroke and its interaction with amyloid deposition in the development of dementia. Althoug. the clinical application of PET

关键词： stroke dementia PET brain metabolism brain ischemia

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Improving.clinical outcomes of patients with hepatocellular carcinoma:Role of antiviral therapy,conversion therapy,and palliative therapy

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World Journal of g.strointestinal Oncolog. 2024年第10期16卷 4037-4041页

作者： Vishal g.Shelat Department of g.neral Surg.ry Tan Tock Seng HospitalSingapore 308433Singapore

In this editorial,I comment on three articles published in the recent issue of the World Journal of g.strointestinal *** carcinoma(HCC)is an important public health concern,and there are three articles on the theme of HCC in this issue.I focus on the articles by Mu et al,Chu et al,and Ma et al for this *** these articles may be considered as low-quality evidence,and the results cannot be g.neralized to non-hepatitis-B or C virus patients,the discussion of the results is *** addition,thoug. all the articles are from China,the relevance of the results is not *** resection is the main form of curative treatment modality owing.to a donor liver shortag.,surg.ons need to be aware that preoperative long.course antiviral therapy can improve clinical outcomes by reducing.postoperative liver dysfunction and recurrence of HCC following.***,patients with super-g.ant HCC(defined as≥15 cm diameter)should also be carefully considered for liver resection,and if it is unresectable upfront,then a combination of liver-directed therapy and systemic therapy may downstag. ***,following.downstag.ng.the patient qualifies for liver resection based on locally prevalent resectability criteria,then such therapy is labelled as conversion(from unresectable to resectable)*** unresectable patients treated by a combination of treatment options,serolog.cal markers like neutrophil-to-lymphocyte ratio and alpha-fetoprotein are reported to predict treatment responses,thus enabling.personalized medicine.

关键词： Antivirals Chemoembolization Conversion therapy Hepatocellular carcinoma Lenvatinib Neutrophil-to-lymphocyte ratio

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