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Distribution of Heavy Metals and Rare Earth Elements in the Surface Sediments of Penang River Estuary, Malaysia

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Open Journal of Marine Science 2016年第1期6卷 79-92页

作者： M. C. ong F. M. Fok K. Sultan b. Joseph School of Marine and Environmental Sciences Universiti Malaysia Terengganu Kuala Terengganu Malaysia Sunda Shelf Research Group Universiti Malaysia Terengganu Kuala Terengganu Malaysia Institute of Oceanography and Environment Universiti Malaysia Terengganu Kuala Terengganu Malaysia

Geochemical sediment of the tropical Pinang River, Malaysia was carried out with the aim at documenting elemental concentrations and pollution level assessment. Concentration of selected heavy metals (Cu, Cd, Cr, Pb, Zn and Mn), rare earth elements, TOC and grain size distribution of sediments were determined at 100 m sampling interval along the river. Sediment size showed a positive correlation with ∑REE and Mn and medium correlations with TOC, Zn, Cu, Cr and Pb contents showing enrichment in the clay size fraction. Results of enrichment factor and geoaccumulation index showed that most of the elemental sources were natural (especially REE) and mostly likely represented background values. However, pollution load index revealed the higher levels of Cr, Cd, Zn and Pb, and, therefore, indicating to the anthropogenic sources (i.e. fishing activities) especially in the downstream locations. Thus, the Pinang River is classified as moderately to highly polluted.

关键词： Heavy Metals REE Tropical River Sediment Pollution Penang Malaysia

Quality of monkeypox information in Wikipedia across multiple languages

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Asian Pacific Journal of Tropical Medicine 2022年第12期15卷 571-572页

作者： Eric David b.Ornos Jared Gabriel L.Dela Rosa Jea Giezl N.Solidum Jervy P.Garcia Erika P.ong Rafael Lorenzo G Valenzuela Ourlad Alzeus G.Tantengco College of Medicine University of the Philippines ManilaErmitaManilaPhilippines Department of Family and Community Medicine Eastern Visayas Medical CenterTacloban CityPhilippines

In recent years,the Internet has become the primary source of health information for the general population,which may be attributed to improvements in digital technology and Internet accessibility[1].Since the World Health Organization declared the coronavirus disease (COVID-19) as a pandemic in March 2020[2],digital information has gained more importance,as seen through the rapid growth in the number of people searching online[3].As seen from previous infectious disease outbreaks,the recent increase in monkeypox cases might compel individuals worldwide to broaden their searches for relevant virtual health information[3,4].

关键词： Wikipedia individual online

磁流变阻尼器最新进展综述:优化设计和应用（英文）

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2017年第12期18卷 991-1010页

作者： Mahmudur RAHMAN Zhi Chao ong Sabariah JULAI Md Meftahul FERDAUS Raju AHAMED Department of Mechanical Engineering Faculty of Engineering University of Malaya Department of Mechatronics Engineering Faculty of Engineering International Islamic University Malaysia

本文对各种磁流变阻尼器的优化设计、制造和智能应用以及自供电和自感应技术的最新进展进行了综述。本文讨论了磁流变阻尼器的基本设计和结构以及各种类型的配置,以了解它们在各种环境和目的下的多功能性。为了应对不同的应用,本文介绍... 详细信息

本文对各种磁流变阻尼器的优化设计、制造和智能应用以及自供电和自感应技术的最新进展进行了综述。本文讨论了磁流变阻尼器的基本设计和结构以及各种类型的配置,以了解它们在各种环境和目的下的多功能性。为了应对不同的应用,本文介绍了设计的修改、优化和改进。节能是当前的终极需求,是对现代技术的挑战。磁流变阻尼器需要改进,以确保较低的电流供应得到较高的效力。这项工作将有助于在各种结构中使用磁流变阻尼器,使其以最小的电流供应进行振动控制,并在优化中获得最佳结果。

关键词：磁流变阻尼器自供电振动控制节能优化和提升

Update on the research and development of magnesium-based biodegradable implants and their clinical translation in orthopaedics

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biomaterials Translational 2021年第3期2卷 188-196页

作者： Ying Luo Jue Wang Michael Tim Yun ong Patrick Shu-hang Yung Jiali Wang Ling Qin School of biomedical Engineering Sun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Hanglok-Tech Co. Ltd.ZhuhaiGuangdong ProvinceChina Musculoskeletal Research Laboratory of Department of Orthopaedics&Traumatology and The Chinese University of Hong Kong Shenzhen-Hong Kong Innovation and Technology Institute(Futian) The Chinese University of Hong KongHong Kong Special Administrative RegionChina

biodegradable magnesium(Mg)or its alloys are desirable materials for development into new-generation internal fixation devices or implants with high biocompatibility,adequate mechanical modulus,and osteopromotive properties,which may overcome some of the drawbacks of the existing permanent orthopaedic implants with regard to stress-shielding of bone and beam-hardening effects on radiographic *** review summarises the current research status of Mg-based orthopaedic implants in animals and clinical ***,detailed information of animal studies including bone fracture repair and anterior cruciate ligament reconstruction with the use of Mg-based orthopaedic devices is ***,the repair mechanisms of the Mg-based orthopaedic implants are also ***,reports of recent clinical cases treated using Mg-based implants in orthopaedics are ***,the challenges and the strategies of the use of Mg-based orthopaedic implants are *** together,the collected efforts in basic research,translational work,and clinical applications of Mg-based orthopaedic implants over the last decades greatly contribute to the development of a new generation of biodegradable metals used for the design of innovative implants for better treatment of orthopaedic conditions in patients with challenging skeletal disorders or injuries.

关键词： ACL reconstruction clinical translation fracture model magnesium orthopaedic implants

Distribution of pericellular matrix molecules in the temporomandibular joint and their chondroprotective effects against inflammation

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International Journal of Oral Science 2017年第1期9卷 43-52页

作者： Wern Cui Chu Shipin Zhang Timothy J Sng Yu Jie ong Wen-Li Tan Vivien Y Ang Casper b Foldager Wei Seong Toh Faculty of Dentistry National University of SingaporeSingapore Orthopaedic Research Laboratory Aarhus University HospitalAarhusDenmark Tissue Engineering Program Life Sciences InstituteNational University of SingaporeSingapore

The objectives of this study were to （1） determine the distribution and synthesis of pericellular matrix （PCM） molecules （collagen VI, collagen IV and laminin） in rat temporomandibular joint （TMJ） and （2） investigate the effects of PCM molecules on chondrocytes against inflammation in osteoarthritis. Four zones （fibrous, proliferating, mature and hypertrophic） of condylar cartilage and three bands （anterior, intermediate and posterior） of disc were analysed by immunohistochemistry for the presence of PCM molecules in rat TMJs. Isolated chondrocytes were pre-treated with PCM molecules before being subjected to interleukin （IL）-II~ treatment to stimulate inflammation. The responses of the chondrocytes were analysed using gene expression, nitric oxide release and matrix metalloproteinase （MMP）-13 production measures. Histomorphometric analyses revealed that the highest areal deposition of collagen VI （67.4%）, collagen IV （45.7%） and laminin （52.4%） was in the proliferating zone of TMJ condylar cartilage. No significant difference in the distribution of PCM molecules was noted among the three bands of the TMJ disc. All three PCM molecules were expressed intracellularly by chondrocytes cultured in the monolayer. Among the PCM molecules, pre-treatment with collagen VI enhanced cellular proliferation, ameliorated IL-lp-induced MMP-3, MMP-9, MMP-13 and inducible nitric oxide synthase gene expression, and attenuated the downregulation of cartilage matrix genes, including collagen I, aggrecan and cartilage oligomeric matrix protein （COMP）. Concurrently, collagen VI pretreatment inhibited nitric oxide and MMP-13 production. Our study demonstrates for the first time the distribution and role of PCM molecules, particularly collagen VI, in the protection of chondrocytes against inflammation.

关键词： cartilage chondrocytes collagen iV collagen W inflammation laminin pericellular matrix temporomandibular joint

高分辨率地震勘探技术在莺歌海盆地大气区勘探中的应用

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天然气工业 1999年第1期19卷 60-64页

作者：谢玉洪中国海洋石油南海西部公司

莺歌海盆地气藏埋藏较浅，含气砂岩的低速特征明显，地震地质条件优越，特别适合于高分辨率地震勘探。西部公司将用于海洋工程调查的一套先进技术应用于莺歌海盆地的天然气勘探，取得了极大的成功，２ｓ以上地震波具有１０～２００Ｈｚ... 详细信息

莺歌海盆地气藏埋藏较浅，含气砂岩的低速特征明显，地震地质条件优越，特别适合于高分辨率地震勘探。西部公司将用于海洋工程调查的一套先进技术应用于莺歌海盆地的天然气勘探，取得了极大的成功，２ｓ以上地震波具有１０～２００Ｈｚ的有效频率范围，可以分辨出５～６ｍ甚至更薄的地层；并且能充分显示出含气砂岩的亮点、平点特征，成为直接找气的一个可靠标志。高分辨率地震资料反演得到的波阻抗剖面，真实地反映了地下的地质情况，在气田的储量评价中，高分辨率地震资料在少量探井控制下，描绘出了砂岩厚度、储层物性变化情况，是气田评价的经济、高效方法。

关键词：海上油气田高分辨率天然气地震勘探储集层

A NOTE ON THE NARROW OPEN CHANNEL RESONANCE

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Journal of Hydrodynamics 2002年第1期14卷 29-37页

作者： Miao Guo-ping (School of Naval Architecture and Ocean Engineering, Shanghai Jiaot ong University, Shanghai 200030, China) H.Ishida, T.Saitoh (Department of Civil Engineering, Kanazawa University, Japan) Sch. of Naval Arch. and Ocean Eng. Shanghai Jiaotong Univ. Shanghai 200030 China

A narrow open channel resonant phenomenon, newly found by the authors in corresponding numerical calculations , was proved to exist based on the method of matching asymptotic expansions for three different channel configurations. It is shown that the resonant wave numbe rk emerges around kL=nπ, n=1,2,3,…∞ with a corresponding frequency s hift, where L is the length of the channel. It is also clear that the resona nce in a narrow open channel is an essential property of a channel as long as it is uniformly narrow.

关键词： narrow open channel resonance the method of matching asymptotic expansions wave diffraction multiple bodies

GAbAb受体的最新进展:从药理学到分子生物学（英文）

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Acta Pharmacologica Sinica 2000年第2期 17-29页

作者： Jennifer ong,David Ib KERR Department of Anaesthesia and Intensive Care The University of Adelaide Ade-laide South Australia 5005 Australia Department of Anaesthesia and Intensive Care The University of Adelaide Ade-laide South Australia 5005 Australia

bicuculline-insensitive receptors for the inhibitory neurotransmitter γ-aminobutyric acid (GAbA), GAbAb receptors, are a distinct subclass of receptors that mediate depression of synaptic transmission and contribute to neu-ronal inhibition. When activated, these receptors reduce transmission at excitatory and inhibitory synapses, as a result of an increase in K+ conductance, or a decrease in voltage-dependent Ca2+ currents. They are also linked to G-proteins, or intracellular effector systems in a very complex manner. The recent development of highly specific and potent agonists and antagonists for these receptors has led to a much better understanding of their physiology and pharmacology, including their heterogeneity, as well as their molecular biology. Over the past year, expression and cloning studies have contributed to major advances in characterizing GAbAb receptor structure, with the discovery of the amino acid sequences of GAbAbRla/R1b splice variants and GAbAbR2 receptors. These isoforms are

关键词： γ-氨基丁酸 GAbA-b受体 GAbAbR2受体巴氯芬 GAbA受体激动剂 GAbA受体拮抗剂

Overview of smartphone applications for sleep analysis

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2016年第1期2卷 -页

作者： Adrian A. ong M. boyd Gillespie Medical University of South Carolina Department of 0tolaryngology e Head and Neck Surgery Charleston SC USA

Objective:To review and assess the current selection of sleep analysis smartphone applications (apps) available for download. Methods:The iOS and Google Play mobile app store were searched for sleep analysis apps tar... 详细信息

Objective:To review and assess the current selection of sleep analysis smartphone applications (apps) available for download. br> Methods:The iOS and Google Play mobile app store were searched for sleep analysis apps tar-geted for consumer use. Alarm clock, sleep-aid, snoring and sleep-talking recorder, fitness tracker apps, and apps geared towards health professionals were excluded. App information and features were obtained from in-store descriptions, and the app developer website. br> Results:A total of 51 unique sleep apps in both iOS and Google Play stores were included. The apps were rated 3.8/5 in both stores, and had an average price of$1.12 in the iOS store and$0.58 in the Google Play store.>65%of sleep apps report on sleep structure, including dura-tion, time awake, and time in light/deep sleep, while reporting of REM was limited. The avail-ability of extra features was variable, ranging from 4%to 73%of apps. br> Conclusions:There are a variety of sleep analysis apps with a range of functionality. The apps with the most reviews from the each store are featured. Many apps provide data on sleep structure;however the algorithms are not validated by scientific literature or studies. Since patients may inquire about their sleep habits from these apps, it is necessary for physicians to be aware of the most common apps and the features offered and their limitations in order to properly counsel patients. br> Copyright a 2016 Chinese Medical Association. Production and hosting by Elsevier b.V. on behalf of KeAi Communications Co., Ltd. This is an open access article under the CC bY-NC-ND license (http://***/licenses/by-nc-nd/4.0/).

关键词： Mobile applications Smartphone Apps Sleep monitor Actigraphy