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Endoscopic retrograde cholangiopancreatography in pancreatic and biliary tract disease in Korean children

World Journal of Gastroenterology 2010年第4期16卷 490-495页

作者： joo Young Jang Chong Hyun Yoon Kyung Mo Kim Department of Pediatrics Asan Medical Center Children's HospitalUniversity of Ulsan College of MedicineSeoul 138-736South Korea Department of Pediatrics Ajou University School of MedicineSuwon 443-721South Korea Department of Pediatric Radiology Asan Medical Center Children's HospitalUniversity of Ulsan College of MedicineSeoul 138-736South Korea Department of Pediatrics Asan Medical Center Children’s HospitalUniversity of Ulsan College of MedicineSeoul 138-736South Korea

AIM:To assess the indications,findings,therapeutic procedures,safety,and complications of endoscopic retrograde cholangiopancreatography(ERCP) performed in Korean ***:The demographic characteristics,indications for ERCP,findings,therapeutic procedures,and complications of 122 pediatric patients who underwent 245 ERCPs in the Asan Medical Center between June 1994 and March 2008 were ***:The mean age of the 122 patients was 8.0 ± 4.2 *** were biliary pathology in 78(64.0%),pancreatic pathology in 43(35.2%),and chronic abdominal pain in *** indications included choledochal cysts in 40,choledocholithiasis in 24,suspected sclerosing cholangitis in 8,trauma in 2,and other conditions in *** indications includedacute pancreatitis in 7,acute recurrent pancreatitis in 11,chronic pancreatitis in 20,trauma in 3,and pancreatic mass in *** the 245 ERCPs,success rate was 98.4% and 190(77.6%) were for therapeutic purposes,including endoscopic nasal drainage(51.8%),biliary sphincterotomy(38.0%),pancreatic sphincterotomy(23.3%),stent insertion(15.1%),stone extraction(18.8%),and balloon dilatation(11.0%).Complications were postERCP pancreatitis in 16(6.5%),ileus in 23(9.4%),hemorrhage in 2(0.8%),perforation in 2(0.8%),sepsis in 1(0.4%),and impacted basket in 1(0.4%).There were no procedure-related deaths,and most complications improved under supportive ***:This study showed that there is a high incidence of choledochal cyst and diagnostic and therapeutic ERCP for the management of various biliary and pancreatic diseases was safe and effective in Korean children.

关键词： Endoscopic retrograde cholangiopancreatography Pancreatic diseases Biliary tract diseases Choledochal cyst Pancreatitis Pediatrics

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Fabrication of Piezoelectric Cellulose Paper and Audio Application

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Journal of Bionic Engineering 2009年第1期6卷 18-21页

作者： Jung-Hwan Kim Sungryul Yun joo-Hyung Kim Jaehwan Kim Creative Research Center for EAPap Actuator Department of Mechanical EngineeringINHA University253 Young-Hyun DongNam GuIncheon402-751Republic of Korea

We report the fabrication process of piezoelectric cellulose paper and the enhancement method of its piezoelectric property. Stretching method with different wet-drawing ratios was introduced to increase the piezoelectric property of cellulose paper during regeneration *** is observed that the Young's modulus and the piezoelectric charge constants are very dependent on the drawing ratio and the direction of nanofibrils of piezoelectric *** the enhanced piezoelectric property,we prove that the flexible regenerated piezoelectric cellulose can be applied to the potential acoustic applications such as thin piezoelectric paper speaker.

关键词： piezoelectric speaker piezoelectricity cellulose wet-drawing process

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Prospective comparison of prophylactic antibiotic use between intravenous moxifloxacin and ceftriaxone for high-risk patients with post-ERCP cholangitis

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Hepatobiliary & Pancreatic Diseases International 2017年第5期16卷 512-518页

作者： Nam Hee Kim Hong joo Kim Ki Bae Bang Department of Internal Medicine Sungkyunkwan University Kangbuk Samsung Hospital Department of Internal Medicine Dankook University Hospital

BACKGROUND: The use of prophylactic antibiotics before endoscopic retrograde cholangiopancreatography(ERCP) is recommended by all major international gastroenterological societies, especially in the presence of an obstructed biliary system. This study compared the occurrence rate of post-procedural complications, including cholangitis and septicemia between prophylactic intravenous moxifloxacin and ceftriaxone in patients with bile duct obstruction scheduled for therapeutic ***: From November 2013 to July 2015, 86 consecutive patients with biliary obstruction with one or more factors predicting benefits of antibiotic prophylaxis prior to ERCP were included in the current randomized open-label non-inferiority trial(Clinical *** identifier NCT02098486). Intravenous moxifloxacin(400 mg/day) or ceftriaxone(2 g/day)were given 90 minutes before ERCP, and were administered for more than 3 days if the patient developed symptoms and signs of cholangitis or septicemia. Recalcitrant cholangitis was defined as persistence of cholangitis for more than 5 days after ERCP or recurrence of cholangitis within 30 days after ***: Recalcitrant cholangitis occurred in 1(2.3%) and 2(4.8%) patients receiving intravenous moxifloxacin and ceftriaxone group, respectively(P=0.612). Septicemia was noted in1(2.3%) and 1(2.4%) patient in intravenous moxifloxacin and ceftriaxone group, respectively(P=1.0). The mean hospital stay was also not significantly different between the moxifloxacin and ceftriaxone groups(8.8±7.2 vs 9.1±9.4 days, P=0.867). Antibiotic resistance of the isolated pathogens by in vitro activity assay was noted in 1(2.3%) and 2(4.8%) patients in the moxifloxacin and ceftriaxone group, respectively(P=0.612). CONCLUSION: Intravenous moxifloxacin is not inferior to intravenous ceftriaxone for the prophylactic treatment of post-ERCP cholangitis and cholangitis-associated morbidity.

关键词： endoscopic retrograde cholangiopancreatography cholangitis moxifloxacin ceftriaxone recalcitrant cholangitis

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Phylogenetic relationship,biogeography,and conservation genetics of endangered Fraxinus chiisanensis(Oleaceae),endemic to South Korea

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Plant Diversity 2022年第2期44卷 170-180页

作者： Changkyun Kim Dong-Kap Kim Hang Sun joo-Hwan Kim Plant Research Division Honam National Institute of Biological ResourcesMokpo 58762Republic of Korea Forest Biodiversity Division Korea National ArboretumPocheon 11186Republic of Korea CAS Key Laboratory for Plant Biodiversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunming 650204YunnanPR China Department of Life Science Gachon UniversitySeongnam 13120Republic of Korea

Endemic plants are important for understanding phylogenetic relationships,biogeographical history,and genetic variation because of their restricted distribution and their role in conserving ***,we investigated the phylogenetic relationships of the Korean endemic Fraxinus chiisanensis by reconstructing the molecular phylogeny of Fraxinus based on two nuclear DNA(nrITS and phantastica)and two chloroplast DNA(psbA-trnH and rp132-trnL)*** our fossil-calibrated phylogenetic framework,we also inferred the biogeographical history of *** provide a scientific basis for the conservation of ***,we determined the levels of genetic diversity and genetic differentiation in this *** information from nuclear and chloroplast DNA sequence data,our molecular phylogenetic analyses identified *** as a genetically distinct unit from its sister group,Fraxinus platypoda from *** molecular dating analyses using nuclear and chloroplast DNA data sets show *** diverged from its sister *** in the Early or Middle Miocene and differentiated in the Late Miocene on the Korean *** results suggest that the divergence of *** was associated with the submergence of the East China Sea land bridge and enhanced monsoons in East *** compared to ***,*** exhibits low genetic diversity within populations and high genetic differentiation among *** results help us to understand the evolutionary history of *** and to develop a conservation strategy for this species.

关键词： East China Sea land bridge Endemic species Fraxinus chiisanensis Korean Peninsula Genetic diversity Biogeography

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Implementation of tactical maneuvers with maneuver libraries

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Chinese Journal of Aeronautics 2020年第1期33卷 255-270页

作者： Do hyeon LEE Chang-joo KIM Sung wook HUR Seong han LEE School of Aerospace Information Engineering Konkuk UniversitySeoul 05029Republic of Korea

This study creates and combines the general maneuver libraries for fixed-wing aircraft to implement tactical ***,the generalized maneuver libraries are established by analyzing the characteristics of tactical maneuvers required in *** 7th order polynomial is applied to both the creation of the maneuver libraries and the generation of the trajectories or flight paths for modal *** track the desired trajectory,we design the Attitude Command Attitude Hold(ACAH)system and the Rate Command Rate Hold(RCRH)system using Model Following Controller(MFC).Moreover,the Line-of-Sight(LOS)guidance law is *** particular,the CONDUIT~?is employed to optimize the gains so that the control systems meet the aircraft Handling Qualities(HQ)***,flight simulations are performed for the longitudinal loop,immelmann-turn,and climb-slalom-descent maneuvers to verify that tactical aggressive maneuvers are realizable via the combination of maneuver *** study can contribute to the development of flight techniques for aircraft tactical maneuvers and to the revision of air force operational manuals.

关键词： 7th order polynomial Attitude command attitude hold system Handling qualities Maneuver libraries Rate command rate hold system Tactical maneuvers

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Liver intravoxel incoherent motion diffusion-weighted imaging for the assessment of hepatic steatosis and fibrosis in children

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World Journal of Gastroenterology 2018年第27期24卷 3013-3020页

作者： Hyun joo Shin Haesung Yoon Myung-joon Kim Seok joo Han Hong Koh Seung Kim Mi-Jung Lee Department of Radiology Severance Hospital Severance Pediatric Liver Disease Research Group Research Institute of Radiological Science Yonsei University College of Medicine Department of Surgery Severance Hospital Severance Pediatric Liver Disease Research Group Yonsei University College of Medicine Division of Gastroenterology Hepatology and Nutrition Department of Pediatrics Severance Children's Hospital Severance Pediatric Liver Disease Research Group Yonsei University College of Medicine

AIM To evaluate the correlation between intravoxel incoherent motion(IVIM) diffusion-weighted imaging(DWI) parameters and the degree of hepatic steatosis and fibrosis in *** This retrospective study was approved by the institutional review board. The children(≤ 18 years) who underwent liver IVIM DWI with 8 b-values under the suspicion of hepatic steatosis or fibrosis from February 2013 to November 2016 were included. Subjects were divided into normal, fatty liver(FAT), and fibrotic liver(FIB) groups. The slow diffusion coefficient(D), fast diffusion coefficient(D*), perfusion fraction(f), and apparent diffusion coefficient(ADC) were measured. MR proton density fat fraction(PDFF), MR elastography(MRE), and IVIM values were *** A total of 123 children(median age of 12 years old, range: 6-18 years) were included, with 8 in the normal group, 93 in the FAT group, and 22 in the FIB group. The D* values were lower in the FIB group compared with those of the normal(P = 0.015) and FAT(P = 0.003) groups. The f values were lower in the FIB group compared with the FAT group(P = 0.001). In multivariate analyses, PDFF value was positively correlated with f value(β = 3.194, P < 0.001), and MRE value was negatively correlated with D* value(β =-7.031, P = 0.032). The D and ADC values were not influenced by PDFF or MRE *** In liver IVIM DWI with multiple b-values in children, there was a positive correlation between hepatic fat and blood volume, and a negative correlation between hepatic stiffness and endovascular blood flow velocity, while diffusion-related parameters were not affected.

关键词： Intravoxel incoherent motion Diffusionweighted imaging Fibrosis Fatty liver Pediatrics

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Corticosteroid-induced bradycardia in multiple sclerosis and maturity-onset diabetes of the young due to hepatocyte nuclear factor 4-alpha mutation:A case report

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World Journal of Clinical Cases 2022年第21期10卷 7415-7421页

作者： Sung-Yeon Sohn Shin Yeop Kim In Soo joo Department of Neurology Ajou University School of MedicineAjou University Medical CenterSuwon 16499South Korea

BACKGROUND Intravenous steroid pulse therapy is the treatment of choice for acute exacerbation of multiple sclerosis(MS).Although steroid administration is generally welltolerated,cases of cardiac arrhythmia have been ***,we describe a young woman who developed marked sinus bradycardia and T-wave abnormalities after corticosteroid *** also present plausible explanations for the abnormalities observed in this *** SUMMARY An 18-year-old woman experienced vertiginous dizziness and binocular diplopia 1 wk prior to *** examination revealed left internuclear ophthalmoplegia with left peripheral-type facial *** initial laboratory results were consistent with those of type 2 *** magnetic resonance imaging revealed multifocal,non-enhancing,symptomatic lesions and multiple enhancing *** was diagnosed with MS and maturity-onset diabetes of the *** methylprednisolone was *** day 5 after methylprednisolone infusion,marked bradycardia with T-wave abnormalities were *** evaluation to elucidate the underlying conditions revealed a hepatocyte nuclear factor 4-alpha(HNF4A)gene *** treatment was discontinued under suspicion of corticosteroid-induced *** electrocardiogram changes returned to normal without complications two days after steroid *** Corticosteroid-induced bradycardia may have a significant clinical impact,especially in patients with comorbidities,such as HNF4A mutations.

关键词： Steroids Bradycardia Multiple sclerosis Maturity-onset diabetes of the young Hepatocyte nuclear factor 4-alpha Case report

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Effects of elastic-plastic properties of materials on residual indentation impressions in nano-indentation using sharp indenter

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中国有色金属学会会刊：英文版 2012年第S3期22卷 585-595页

作者： Jung-Min LEE Chan-joo LEE Kyung-Hun LEE Byung-Min KIM Dongnam Regional Division Korea Institute of Industrial Technology Precision Manufacturing Systems Division Pusan National University School of Mechanical Engineering Pusan National University

One of the primary features of nano-indentation technique is that the contact area induced by an indenter is indirectly measured by a relationship between the penetration depth and the known geometry of the ***,this indirect measurement occasionally leads to inaccurate properties of the indented *** objective of this study is to investigate the effects of E/σr and the strain hardening exponents n of materials on the behaviors of pile-up and sink-in in nano-indentation and to predict n values of materials from the residual indentation *** relations between the residual indentation profile and n value of the indented material were identified by dimensional ***,they were numerically formulated using FE analysis of nano-indentation for 140 different combinations of elastic-plastic parameters such as E,σy and *** parameters of hrp/hm,herp/hm,Rr/hm and HO&P/Hreal were introduced as various dimensionless parameters to represent and quantify the residual indentation profile after *** were subsequently characterized as dimensionless functions using n and E/σr ***,the validity of these functions was verified through 3D FE analysis of nano-indentation for Al 6061-T6 and AISI 1010 materials.

关键词： nano-indentation pile-up sink-in strain hardening exponent FE simulation

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Contribution of multiple reflections to light utilization efficiency of submicron hollow TiO_2 photocatalyst

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Science China Materials 2016年第12期59卷 1017-1026页

作者：刘红艳马华 Jibong joo 殷亚东 Key Laboratory of Luminescent and Real-Time Analytical Chemistry Ministry of EducationCollege of Chemistry and Chemical EngineeringSouthwest UniversityChongqing 400715China Department of Chemistry and UCR Center for Catalysis University of CaliforniaRiversideCA 92521USA College of Chemistry and Chemical Engineering Lanzhou UniversityLanzhou 730000China Department of Chemical Engineering Konkuk University120 Neungdong-RoGwangjin-GuSeoulRepublic of Korea

In this work,we carried out both theoretical calculation and experimental studies to reveal the contribution of hollow geometry to the light utilization efficiency of the TiO_2 photocatalysts in diluted aqueous *** is found that the single or multi-shelled hollow structures do not induce significant multiple reflections within the shells as widely believed in previous reports,and therefore the geometric factor has minimal contribution to the improvement of the light utilization efficiency of the *** design TiO_2 photocatalysts with higher activity,it is more appropriate to focus on the improvement of the crystallinity,diffusion,surface area,and dispersity of the catalysts,rather than their geometric shapes.

关键词： multiple reflections photocatalysis TiO2 hollow shell

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Observational Study of Surface Wind along a Sloping Surface over Mountainous Terrain during Winter

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Advances in Atmospheric Sciences 2018年第3期35卷 276-284页

作者： Young-Hee LEE Gyuwon LEE Sangwon joo Kwang-Deuk AHN Department of Astronomy and Atmospheric Sciences Kyungpook National University Numerical Data Application Division Numerical Modeling Center

The 2018 Winter Olympic and Paralympic Games will be held in Pyeongchang, Korea, during February and March. We examined the near surface winds and wind gusts along the sloping surface at two outdoor venues in Pyeongchang during February and March using surface wind data. The outdoor venues are located in a complex, mountainous terrain, and hence the near-surface winds form intricate patterns due to the interplay between large-scale and locally forced winds. During February and March, the dominant wind at the ridge level is westerly; however, a significant wind direction change is ob- served along the sloping surface at the venues. The winds on the sloping surface are also influenced by thermal forcing, showing increased upslope flow during daytime. When neutral air flows over the hill, the windward and leeward flows show a significantly different behavior. A higher correlation of the wind speed between upper- and lower-level stations is shown in the windward region compared with the leeward region. The strong synoptic wind, small width of the ridge, and steep leeward ridge slope angle provide favorable conditions for flow separation at the leeward toot of the ridge. The gust factor increases with decreasing surface elevation and is larger during daytime than nighttime. A significantly large gust factor is also observed in the leeward region.

关键词： flow separation gust factor leeward region sloping surface

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