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Perceived Improvements of Quality of Life (QoL) among Patients with Idiopathic Pulmonary Fibrosis (IPF) in Response to a 6-Week Rehabilitation Program

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Open Journal of Respiratory Diseases 2021年第2期11卷 27-36页

作者： Sameera Peumal Senanayake Rathugamage Sithija Priyankara Fernando heeraluge erandie hasini perera Ridmi Shashiprabha Maddumage Athuraliya Gamacharige Kasuni Neranja Kathaluwa Liyana Kankanamge Tharini Dilanka Sandharenu Faculty of Allied Health Sciences General Sir John Kotelawala Defence University Werahara Sri Lanka School of Sports Sciences Swansea University Wales United Kingdom

Idiopathic pulmonary fibrosis (IPF) is a chronic, life-limiting with an average life expectancy of 05 years following the onset of the disease, with no curative treatments. These patients need palliative care and rehabilitation is one of the methods that can be used to improve quality of life (QoL) among these patients. Yet the research conducted to assess benefits of pulmonary rehabilitation (PR) in terms of improving physical activity and QoL in IPF patients remains limited. Hence this study aims to evaluate the effect of a bespoke pulmonary rehabilitation programme, on the physical, physiological and psychological parameters and improvements of QoL among IPF patients. Eleven (11) subjects with IPF received 6 weeks of pulmonary rehabilitation. An interviewer administered quality of life questionnaire, six-minute walking test (6MWT), Incremental bicycle exercise tests were performed, and cardiac and respiratory parameters were assessed pre- and post-rehabilitation. The 6MWT was significantly increased following training (Pre 312.55 ± 89.99;Post, 380.73 ± 59.60). A significant improvement was observed in overall QoL (2.226 ± 0.026), dyspnoea (-0.455 ± 0.004) anxiety (-2.070 ± 0.038), depression (-2.217 ± 0.027) scores. No significant changes were found in the VO2 max and other cardiopulmonary parameters, while non-significant improvement was seen in SpO2 at peak exercise from 85.8 - 86.5. Bespoke pulmonary rehabilitation program is beneficial in short term improvement of the functional exercise capacity, dyspnoea and QoL among IPF patients.

关键词： IPF 6MWT Pulmonary Rehabilitation QoL Oxygen Uptake VO2

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Patients’ Experiences and Opinions on Pulmonary Rehabilitation and Use of It as a Tool of Palliative Care on Idiopathic Pulmonary Fibrosis (IPF)

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Open Journal of Respiratory Diseases 2021年第2期11卷 61-75页

作者： Sameera Peumal Senanayake Kalpani Abhayasinghe Rathugamage Sithija Priyankara Fernando heeraluge erandie hasini perera Ridmi Shashiprabha Maddumage Athuraliya Gamacharige Kasuni Neranja Kathaluwa Liyana Kankanamge Tharini Dilanka Sandharenu Faculty of Allied Health Sciences General Sir John Kotelawala Defence University Ratmalana Sri Lanka School of Sports Sciences Swansea University Swansea Wales UK Institute for Research and Development in Health and Social Care Colombo Sri Lanka

Background: Idiopathic Pulmonary Fibrosis (IPF) is a chronic, progressive, and life-limiting condition. It has no cure hence it is vital to establish effective methods of improving the quality of remaining life in these patients. One of the key components of improving quality of life is pulmonary rehabilitation. However little research has been conducted to understand the perspectives and lived experience of people with IPF on pulmonary rehabilitation. Hence, we aim to fill this gap in the existing literature. Methods: We sought to understand how patients coped with pulmonary rehabilitation. A patient-centred approach was used to explore the physical and psychological impact of pulmonary rehabilitation. Semi-structured interviews were conducted by experienced academics. Interviews used a topic guide but mostly led by the participants. An inductive thematic approach was used to analyse data, allowing us to identify common themes in the participants’ experiences. Results: Of fifty invited participants, ten took part in the study (aged 53 - 81 years). Inductive analysis of interviews identified seven second-order themes and eleven first-order themes, represented by two General Dimensions: “motivation

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