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Nano Research 2008年第4期1卷 351-360页

作者： Hye Kyung Moon Chan Il Chang Dong-Ki Lee hee cheul choi Department of Chemistry Pohang University of Science and Technology(POSTECH)San 31Hyoja-DongNam-guPohang 790-784Korea Department of Chemistry Sungkyunkwan UniversityNatural Science CampusSuwon 440-746Korea

Nuclease effects on the cell internalization of single-walled carbon nanotubes(SWNTs)functionalized with fluorescent-labeled DNA in serum containing cell growth media were *** Cy3-labeled DNA-functionalized SWNT conjugates(Cy3DNA-SWNTs)were incubated with HeLa cells in a fatal bovine serum(FBS)medium,a high fl uorescence intensity was obtained from the cells,indicative for the high level inclusion of ***,the fluorescence intensity was remarkably reduced if Cy3DNA-SWNTs were incubated with cells in the FBS-free *** systematic control experiments revealed that Cy3 dye molecules were released from Cy3DNA-SWNT conjugates by nuclease,and the free Cy3 dyes penetrate into HeLa cell with high *** the actual amounts of SWNTs internalized in the cells were almost identical for both cells incubated in the FBS-present and FBS-absent media according to the Raman measurements,one should be cautious to determine the degree of SWNT internalization based on the fl uorescence intensities especially when the coloring dye molecules were linked to oligonucleotides in nuclease containing media.

关键词： Single-walled carbon nanotube oligonucleotide cellular delivery molecular transporter nuclease

Randomized Clinical Trials on Eastern-Western Integrative Medicine for Health Care in Korean Literature:A Systematic Review

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Chinese Journal of Integrative Medicine 2011年第1期17卷 48-51页

作者： Myeong Soo Lee Byung-cheul Shin Tae-Young choi Jong-In KimDepartment of Acupuncture and Moxibustion Kyung hee University Seoul South Korea Korea Institute of Oriental Medicine DaejeonSouth Korea Division of Clinical Medicine School of Korean MedicinePusan National UniversityYangsanSouth Korea

Objective：To summarize and critically evaluate the evidence for and against the effectiveness of Eastern-Western integrative medicine（EWIM） for health care compared to Eastern medicine（EM） or Western medicine（WM） ***：Systematic searches were conducted on five Korean medical *** searches were also conducted through nine major Korean medical *** randomized clinical trials （RCTs） were included if EWIM was tested for any type of conditions compared to EM or ***：There were one hundred forty-one possibly relevant studies were identified,and seven RCTs were *** risk of bias was high in most *** EWIM methods were compared with EM or WM in patients with pain conditions in four *** studies showed favorable effects of EWIM on pain reduction in patients with shoulder pain and chronic headache compared with EM,while the other RCTs failed to do so in traffic injury *** studies tested EWIM in patients with Bell＇s palsy compared with EM and found acute functional *** RCT comparing EWIM with WM in patients with acne showed a significant ***：The results of our systematic review suggest that there is limited evidence for the superiority of EWIM over EM or WM in the treatment of pain and acute symptom improvement in patients with Bell＇s *** evidence from our analysis was limited from the low number of RCTs included and the high risk of *** RCTs appear to be warranted.

关键词： Eastern-Western integrative medicine systematic review randomized clinical trial Korean literature

Influence of the wastewater composition on denitrification and biological P-removal in the S-DN-P process: (c) Dissolved and undissolved substrates

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Journal of Environmental Sciences 2009年第8期21卷 1074-1079页

作者： hee-Jeong choi Chul-Ho choi Seung-Mok Lee Diwakar Tiwari Department of Environmental Engineering Kwandong University Department of Chemistry School of Physical Sciences Mizoram University

The denitdfication and P-removal in the sorption-denitrification-P-removal （S-DN-P） process were carded out under various wastewater compositions. It is noted that P-removal largely depends on the wastewater composition as well to the quantity of the substrates present in wastewater fraction. Three different wastewater fractions are obtained as： raw wastewater, dissolved wastewater （obtained with filtration using 0.45 μm filter）, and undissolved wastewater （i.e., infiltrate obtained by above filtration）. The ratio of P-release/CODtotal-consumption clearly inferred that undissolved wastewater possess very low value i.e., 0.0008 followed by raw wastewater 0.008 and dissolved wastewater 0.03. When this ratio was nearby 0.01, enhanced P-removal was observed. Moreover, the ratio of P-uptake to NO3^--N decomposition for raw wastewater was two times for dissolved wastewater. Interestingly, it was observed that the P-removal and denitrification depend not only on the dissolved substrates but also the undissolved substrates present in the wastewater. The result of the P-removal obtained with this S-DN-P process did not show a big difference of 36%, 34% and 30%, respectively, for raw, dissolved and undissolved wastewater.

关键词： denitrification polyhydroxybutyrate sequencing batch biofilm reactor sorption denitrification P-removals

Antioxidant and anticancer activity of Artemisia princeps *** extract in HepG2 and Hep3B hepatocellular carcinoma cells

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Chinese Journal of Cancer Research 2013年第5期25卷 536-543页

作者： Eun-Jeong choi Gun-hee Kim Plant Resources Research Institute Duksung Women's University

Objective：The aim of the present study was to investigate antioxidant and the anticancerigen activity of a methanol extract from Artemisia princeps *** （APME）,a well-known traditional herbal medicine in Asia,in hepatocellular cancer ***：To evaluate the antioxidant activity of APME,reactive oxygen species （ROS） and the antioxidant enzymes,superoxide dismutase （SOD） and catalase were investigated in HepG2 cells exposed to APME （5,100,and 200 μg/mL） for 72 ***,to evaluate the anticancer activity of APME,we investigated the proliferation and apoptosis induction of HepG2 and Hep3B cells exposed to APME （1-200 μg/mL） for 24,48,and 72 ***：APME dose-dependently reduced the generation of ROS in the presence of H2O2 compared with control ***,it increased catalase and SOD ***,APME inhibited cell proliferation in a dose-and time-dependcnt manner,but at concentrations lower than 100 μg/mL,the inhibition was less dose-dependent than ***2 and Hep3B cells exposed to 5,100,and 200 μg/mL APME for 72 h underwent cell cycle arrest and *** to APME resulted in a significant increase in the number of cells in G1 phase and a decrease in the G2/M phase cell *** addition,APME induced P53 expression of HepG2 cells in a dose-dependent manner,and played a role in the downregulation of Bcl-2 and upregulation of Bax in both HepG2 and Hep3B ***：These results indicate the potential role of APME as an antioxidant and anticancerigen agent in hepatocarcinoma cell lines.

关键词： Artemisia princeps var.orientalis antioxidant anticancer hepatocellular carcinoma

A case of gouty arthritis following percutaneous radiofrequency ablation for hepatocellular carcinoma

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World Journal of Gastroenterology 2010年第6期16卷 778-781页

作者： Dae hee choi Hyo-Suk Lee Department of Internal Medicine Kangwon National University College of Medicine Department of Internal Medicine and Liver Research Institute Seoul National University College of Medicine

Percutaneous radiofrequency thermal ablation(RFA) is considered an effective technique for providing local control in the majority of Hepatocellular carcinoma(HCC) *** RFA is generally well tolerated,recent studies have reported complications associated with *** describe a case of acute gouty arthritis in a 71-year-old man with chronic renal failure who was treated with RFA for a HCC lesion and who had hepatitis B-associated cirrhosis and mild renal *** surveillance of the patient detected a 3.5 cm HCC *** the patient had declined surgery,RFA was chosen for *** the third post-procedural day,the laboratory results showed increases in his uric acid and potassium levels,which were compatible with a tumor lysis syndrome. On the 6th post-procedural day,the patient complained of new right knee *** joint aspiration revealed monosodium urate monohydrate *** made the diagnosis of acute gouty arthritis arising from tumor lysis and liver infarction caused by HCC ablation,which was aggravated by acute renal insufficiency. After adequate hydration and administration of oral colchicines,the patient's right knee pain subsided andthe uric acid serum level returned to *** is the first described case of acute gouty arthritis after RFA for a HCC lesion in a patient with underlying chronic renal *** avoid hyperuricemia and an acute attack of gout after RFA therapy for HCC,early identification of patients at risk is warranted,such as those with a large tumor,rapid tumor growth,and renal insufficiency,and preventative measures should be considered.

关键词： Radiofrequency thermal ablation Hepatocellular carcinoma Gout Tumor lysis syndrome Complications

Consistency of intensity ratio between spectral lines with similar self-absorption characteristics during ungated laser induced breakdown spectroscopy measurements

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Plasma Science and Technology 2019年第3期21卷 77-83页

作者： Jung-Hwan IN Youngmin MOON Jang-hee choi Sungho JEONG Optical Lens Research Center Korea Photonics Technology Institute School of Mechanical Engineering Gwangju Institute of Science and Technology

This work reports that the intensity ratio of spectral lines having similar self-absorption characteristics during laser induced breakdown spectroscopy(LIBS) analysis can become nearly constant over a wide range of irradiation conditions if the intensities are integrated over a sufficiently long time. It is shown that the plasma temperature and intensity ratio of these spectral lines have temporal similarity. The spectral lines with similar self-absorption properties may be selected to improve the accuracy and consistency of LIBS analysis results under an environment with fluctuating measurement conditions.

关键词： laser induced breakdown spectroscopy intensity ratio self-absorption characteristics CIGS solar cell

Investigations of an Air Starting Motor of Marine Medium-Speed Diesel Engine with Numerical Analyses

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Journal of Thermal Science 2010年第2期19卷 148-153页

作者： Yeon Won Lee Yoon Hwan choi Deog hee Doh Division of Mechanical Eng. Pukyong National Univ.San 100 Division of Mechanical and Information Eng.

The marine medium-speed diesel engines are started by two methods;one is the electric motors,and the other air starting *** though air starting motor is dependent of the engine types and sizes,it has been widely used in this area due to its simplicity,convenience and *** purpose of this paper is to give the designing parameters in order to make a proper "Air Starting Motor" using *** aerodynamic approaches were given to understand the internal flow characteristics of the air starting *** addition,we have carried out the investigation of effects of tip *** the calculations the tip clearance of air starting motor has been varied between 0,2.8,4.3 and 5.7% of blade *** results of computation are the tip clearance increased to 2.8%,the torque decreased 24%,and there was no more large changes when the clearances increased to 4.3% and 5.7%.

关键词： Medium-Speed Diesel Engine Air Starting Motor CFD Tip Clearance Influences

Temperature Distribution and Thermal Stresses in Various Conditions of Moving Heating Source during Line Heating Process

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Journal of Thermal Science 2012年第1期21卷 82-87页

作者： Yoon Hwan choi Yeon Won Lee Kwang choi Deog hee Doh Kyoung Joon Kim Department of Mechanical and Automotive Engineering Pukyong National University Steel Structure Research Division Research Institute of Industrial Science & Technology Division of Mechanical and information Engineering Korea Maritime University

Line heating method is widely used to manufacture curved surfaces in ship building. The main factors governing the quality of the manufactured products are the moving velocity of the heating source, heating strength, and heating ways. In this study, the temperature distributions of the heated plate were investigated with the condition that the line heating process was automatic. The temperature variations were also investigated with the changes of those three variables. The numerical results showed that the peak temperature decreased as the moving velocity of the heating source increased. It also revealed that the peak temperatures changed linearly with the changes of the heating source.

关键词： Moving heat source Line heating Thermal stress Residual deformation Conductive heat transfer

Moxibustion for Managing Type 2 Diabetes Mellitus:A Systematic Review

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Chinese Journal of Integrative Medicine 2011年第8期17卷 575-579页

作者： Tae-Hun Kim Tae-Yong choi Byung-cheul Shin Myeong Soo Lee Department of Cardiovascular and Neurologic Diseases College of Oriental MedicineGraduate SchoolKyung Hee University Acupuncture Moxibustion and Meridian Research CenterKorea Institute of Oriental Medicine Brain Disease Research Centre Korea Institute of Oriental Medicine Division of Clinical Medicine School of Korean MedicinePusan National University

Objective：Moxibustion is currently used for treating diabetes mellitus（DM） as a non-drug intervention in East Asian *** systematic review aims to evaluate the effectiveness of moxibustion for managing the symptoms of type 2 DM ***：We searched MEDLINE,AMED,EMBASE,CINAHL, The Cochrane Library,six Korean databases,and four Chinese *** of bias was used for evaluating the quality of the included ***：A total of 5 studies met the inclusion criteria for this *** of the included studies had high risks of *** randomized clinical trial（RCT） compared the effectiveness of one-time moxibustion use with oral administration of glibenclimide and showed the significant effects of moxibustion on glycemic *** RCT tested the effectiveness of moxibustion plus conventional treatment,and the moxibustion group reported significant improvement in fasting and postprandial blood glucose levels compared with the conventional treatment *** RCTs compared the effectiveness of moxibustion versus acupuncture or moxibustion plus acupuncture,and the combined treatment showed the most favorable effects on the control of blood glucose,urine glucose,and glycocylated hemoglobin A_（1C）（HbA_（1C））.One uncontrolled observational study showed favorable effects of moxibustion on the response ***：It is difficult to conclude that moxibustion is an effective intervention for the control of type 2 DM due to the scarcity of trials and the low methodological quality of included *** rigorous RCTs may be necessary to evaluate the effectiveness of moxibustion for type 2 DM.

关键词： moxibustion diabetes mellitus type 2 diabetes mellitus blood glucose systematic review

Projections of ocean climate for northwestern Pacific Ocean

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Acta Oceanologica Sinica 2005年第1期24卷 134-145页

作者： choi Byung Ho KIM Dong Hoon choi Young Jin YUK Jin hee Department of Civil and Environmental Engineering Sungkyunkwan University Suwon KoreaAbiko Research Laboratory Central Research Institute of Electric Power Industry JapanResearch Institute of Applied Mechanics Kyushu University JapanDepartment of Civil and Environmental Engineering Sungkyunkwan University Suwon Korea

The long-term adjustment processes of atmosphere and ocean in response to gradually increased atmospheric CO2 concentration have been analyzed in 70 and 140 a integrations with NCAR fully-coupled climate system model (CSM). In these experiments the CO2 concentration has been increased to double and quadruples the initial concentration, respectively. After 70 a, at the time of CO2 doubling, the model predicts surface air temperature rises by 1.2 and 1.5 K for the globe and the northwestern Pacific Ocean, respectively. The behavior of the quadrupling run is similar: each global and regional mean surface air temperatures increase by 2.8 and 3.0 K at the time of CO2 quadrupling. From the experiments, surface air temperature changes in the northwestern Pacific Ocean will be more distinctive compared with the global average, mainly due to exceptionally large wanning and sea level change near the entrance of the Kuroshio extension.

关键词： Climate model simulation global warming northwestern Pacific Ocean