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Molecular Plant 2019年第1期12卷 71-85页

作者： Rocio Sanchez-Montesino Laura Bouza-Morcillo julietta Marquez Melania Ghita Salva Duran-Nebreda Luis gomez Michael j.Holdsworth George Bassel Luis Onate-Sanchez Centro de Biotecnologia y Genomica de Plantas Universidad Politecnica de Madrid-lnstituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria Campus de MontegancedoPozuelo de AlarconMaddd 28223Spain School of Biosciences University of NottinghamLoughborough LE12 5RDUK School of Biosciences University of BirminghamBirmingham B15 23-rUK Departamento de Sistemas y Recursos Naturales E.T.S.I.MontesForestal y del Medio NaturalCampus de Moncloa28040 MadridSpain

A key component of seed germination is the interplay of mechanical forces governing embryo growth and the surrounding restraining endosperm *** cell separation is therefore thought to play a critical role in the control of this developmental *** we demonstrate that in Arabidopsis thaliana seeds,endosperm cell expansion is a key component of *** cells expand to accommodate embryo growth prior to *** show that this is an actively regulated process supported by spatiotemporal control of the cell expansion gene EXPANSIN 2 (EXPA2).The NAC transcription factors NAC25 and NACIL were identified as upstream regulators of EXPA2 expression,gibbereliinmediated endosperm expansion,and seed *** DELLA protein RGL2 repressed activation of the EXPA2 promoter by NAC25/*** together,our findings uncover a key role of the GA/ DELLA-NAC25/NACIL-EXPA2 network in regulating endosperm cell expansion to control the seed-toseedling transition.

关键词： cell expansion cell-wall remodeling enzymes endosperm expansin NAC transcription factors seed germination

Single nucleotide polymorPhisms in CBLB, a marker gene of immunity regulator,predict radiation pneumonitis and outcomes in NSCLC patients after definite radiotherapy

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Single nucleotide polymorPhisms in CBLB, a marker gene of im...

第八届中国肿瘤学术大会暨第十三届海峡两岸肿瘤学术会议

作者： Peng Li Xiaohong Wang Hongliang Liu Ting Xu Huijuan Wang D.R.gomez Q.L.Nguyen Li-e Wang Yue-e Teng YiPeng Song R.Komaki j.Welsh Qingyi Wei Zhongxing Liao DePartments of 1Radiation Oncology and 2EPidemiology the University of Texas M. D.Anderson Cancer Center DePartment of Internal Medicine Affiliated Cancer HosPital of Zhengzhou University Duke Cancer Institute Duke University Medical Center DePartment of Medical Oncology the First HosPital of China Medical University DePartment of Radiation Oncology Affiliated Yantai Yuhuangding HosPital of Qingdaom University

＜正＞Background The immune system Plays an imPortant role in regulating tumor develoPment as well as outcomes to cancer *** B-lineage lymPhoma b Protein（Cbl-b）is an E3 ubiquitin ligase that Plays a key role in main...

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一所大学建筑中用高效率的照明合理使用电能

供用电 2003年第6期20卷 6-9页

作者： A.Gabaldon A.Molina C.Roldan j.A.Fuentes E.gomez F.Marin F.SeQuera P.Morales 西班牙西班牙西班牙西班牙西班牙西班牙西班牙西班牙

0引言为了在用能效率上作出工程努力,Cortagena技术大学去年4月已决定实施一项雄心勃勃的计划,要在此后的4年中削减用电费用.为了证实不同政策的可行性和成本效益,应用于原海军医院(工业工程高等技术学校总部)的许多展示活动将在最近期... 详细信息

0引言为了在用能效率上作出工程努力,Cortagena技术大学去年4月已决定实施一项雄心勃勃的计划,要在此后的4年中削减用电费用.为了证实不同政策的可行性和成本效益,应用于原海军医院(工业工程高等技术学校总部)的许多展示活动将在最近期内完成.当然,在此建筑中合理用电的对象将集中在两个主要的电气末端即:电热和空调,以及照明.本文将描述原海军医院照明需量的现状:用电量,约束条件,机会和平面蓝图,以便完成照明末端用电的显著改善.

关键词：高校建筑电气照明电能绿色照明建筑物

组织蛋白酶C纯合突变与Haim-Munk综合征有关

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世界核心医学期刊文摘（皮肤病学分册） 2005年第7期1卷 13-14页

作者： Cury V.F. gomez R.S. Costa j.E. L.De Marco 李晓莉冯义国 Department of Pharmacology Inst. de Cie..Biol. Universidade Federal de Minas Gerais Av. Antonio Carlos 6627 Belo Horizonte 31270-901 Brazil

Haim-Munk syndrome (HMS) is a rare autosomal recessive disorder characterized clinically by abnormal palmoplantar hyperkeratosis and destruction of the periodontium, with hallmarks of onychogryphosis and arachnodactyly. Germline mutations in the lysosomal protease cathepsin C gene (CTSC)have been described in a single patient with HMS and in several individuals with the clinically related disorderPapillon-Lef` evre syndrome (PLS). We describe a patient with HMS. We have analysed the cathepsin C gene in the proband and her mother. Sequence analysis of CTSC in the proband revealed a homozygous mutation at codon 196 (587T → C) within exon 4 that altered the conserved leucine to proline (Leu196Pro), whereas the patient’ s mother was heterozygous for that mutation. The same mutation has previously been described in an unrelated Brazilian family with PLS. An identical single missense mutation in the cathepsin C gene may underlie both PLS and HMS. These findings confirm that HMS and PLS are allelic variants of cathepsin C gene mutations and suggest that other factors (environmental or genetic) may be important determinants of the clinical phenotype of HMS and PLS.

关键词：纯合突变 Haim-Munk 组织蛋白酶基因突变先证者异常角化牙周组织破坏掌跖甲弯曲杂合突变

Ecohydrological advances and applications in plant–water relations research:a review

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journal of Plant Ecology 2011年第1期4卷 192-192页

作者： H.Asbjornsen G.R.Goldsmith M.S.Alvarado-Barrientos K.Rebel F.P.Van Osch M.Rietkerk j.Chen S.Gotsch C.Tobon D.R.Geissert A.gomez-Tagle K.Vache T.E.Dawson Department of Natural Resources and the Environment University of New Hampshire Durham NH 03824 USA Department of Integrative Biology University of California Berkeley Berkeley CA 94720 USA Department of Environmental Sciences Copernicus Institute of Sustainable Development Utrecht University Utrecht 3508TC The Netherlands Department of Environmental Sciences University of Toledo OH 43606 USA Department of Forest Sciences National University of Colombia Medellín Colombia Department of Functional Ecology Institute of Ecology Xalapa 91070 Mexico Department of Earth Sciences University of Michoacán Morelia Michoacán 58330 Mexico Department of Biological and Ecological Engineering Oregon State University Corvallis OR 97331 USA

Aims The field of ecohydrology is providing new theoretical frameworks and methodological approaches for understanding the complex interactions and feedbacks between vegetation and hydrologic flows at multiple scales. Here we review some of the major scientific and technological advances in ecohydrology as related to understanding the mechanisms by which plant-water relations influence water fluxes at ecosystem, watershed and landscape scales. Important Findings We identify several cross-cutting themes related to the role of plant-water relations in the ecohydrological literature, including the contrasting dynamics of water-limited and water-abundant ecosystems, transferring information about water fluxes across scales, understanding spatiotemporal heterogeneity and complexity, ecohydrological triggers associated with threshold behavior and shifts between alternative stable states and the need for long-term data sets at multiple scales. We then show how these themes are embedded within three key research areas where improved understanding of the linkages between plant-water relations and the hydrologic cycle have led to important advances in the field of ecohydrology: upscaling water fluxes from the leaf to the watershed and landscape, effects of plant-soil interactions on soil moisture dynamics and controls exerted by plant water use patterns and mechanisms on streamflow regime. In particular, we highlight several pressing environmental challenges facing society today where ecohydrology can contribute to the scientific knowledge for developing sound management and policy solutions. We conclude by identifying key challenges and opportunities for advancing contributions of plant-water relations research to ecohydrology in the future. © The Author 2011. Published by Oxford University Press on behalf of the Institute of Botany, Chinese Academy of Sciences and the Botanical Society of China.

关键词： ecohydrology plant water use regime shift thresholds scaling transpiration

Carbon stocks in a highly fragmented landscape with seasonally dry tropical forest in the Neotropics

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Forest Ecosystems 2022年第2期9卷 168-177页

作者： N.Mesa-Sierra j.Laborde R.Chaplin-Kramer F.Escobar Instituto Tecnologico y de Estudios Superiores de Occidente Centro Interdisciplinario para la Formacion y Vinculacion SocialPeriferico Sur Manuel Gomez Morin 858545604TlaquepaqueJaliscoMexico Gnosis-Naturaleza con ciencia A.C.Lorenzo Barcelata 510145239GuadalajaraJaliscoMexico Instituto de Ecologia A.C.Ecologia FuncionalCarretera Antigua a Coatepec 351El Haya91073XalapaVeracruzMexico Natural Capital Project Woods Institute for the EnvironmentStanford University327 Campus DriveStanfordCA94305USA Institute on the Environment University of Minnesota1954 Buford AveSt.PaulMinnesota55108USA Instituto de Ecologia A.C.EcoetologiaCarretera Antigua a Coatepec 351El Haya91073XalapaVeracruzMexico

Background:Global modeling of carbon storage and sequestration often mischaracterizes unique ecosystems such as the seasonally dry tropical forest of the central region of the Gulf of Mexico,because species diversity is usually underestimated,as is their carbon *** this study,aboveground and soil carbon stocks were estimated to determine the climate mitigation potential of this highly degraded landscape(<25%of forest cover).Results:Tree species in the study area had carbon content values that were 30%–40%higher than the standard value proposed by the IPCC(i.e.,50%).Tropical oak forest in the region,despite its restricted distribution and low species richness,accounted for the highest mean carbon stocks per unit *** main factors driving spatial variability in carbon stocks were:maximum precipitation,soil organic matter,clay and silt *** strong relationship was found between aboveground carbon stocks and soil organic carbon in the study ***-fication of carbon stocks is an important consideration in the assessment of the conservation value of remnants of native vegetation in human-modified ***:This study demonstrates the importance of the highly fragmented tropical dry regions of the Neo-tropics in maintaining landscape functionality and providing key ecosystem services such as carbon *** results also highlight how crucial field-based studies are for strengthening the accuracy of global ***,this approach reveals the real contribution of ecosystems that are not commonly taken into account in the mitigation of climate change effects.

关键词： Seasonally dry tropical region Ecosystem services Carbon sequestration Human modified landscapes Climate change mitigation

玉米花粉寿命及有效控制花粉飘逸的隔离距离研究

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中国农技推广 2009年第12期25卷 12-13页

作者：马志强何庆学 S.Luna V. j.Figueroa M. B.Baltazar M. R.gomez L. R.Townsend j.B.Schoper 全国农业技术推广服务中心北京100125 墨西哥先锋种子公司

花粉是玉米基因飘逸的重要载体。研究了花粉活力的持续时间和有效控制基因飘逸的隔离距离。在花药刚开裂时采集花粉,置于薄膜层上,放在室外自然条件下保存,每隔一定时间对采集的花粉进行目测和授粉,通过对花粉的目测评判和计算结实率评... 详细信息

花粉是玉米基因飘逸的重要载体。研究了花粉活力的持续时间和有效控制基因飘逸的隔离距离。在花药刚开裂时采集花粉,置于薄膜层上,放在室外自然条件下保存,每隔一定时间对采集的花粉进行目测和授粉,通过对花粉的目测评判和计算结实率评估花粉活力。试验花粉源区域4000m2,在其周围不同距离的地方种植若干玉米小区,每个小区面积为12.8m2,以测定隔离距离的有效性。作为花粉源的玉米材料包含可用于测定花粉飘逸的叶色标记或种子标记。由于大气压不同,花粉可在花药开裂后1～2小时内保持活力。假定花粉以当地下午平均最大风速直线传播,并可在2小时内保持花粉活力,且忽略花粉沉降率因素,理论上讲,具有活力的花粉可以传播的最大距离为32km。试验结果是在离花粉源100m发生了一定数量的异花授粉,离花粉源200m处有个别异花授粉发生,离花粉源300m处没有异花授粉发生。试验结果与玉米花粉不耐干燥并具高沉降速率的结论一致。试验结果表明距离隔离是控制玉米因授粉而发生基因飘逸的有效方法。

关键词：玉米花粉飘逸隔离距离

Interaction between age and gender on survival outcomes in extramedullary multiple myeloma over the past two decades

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World journal of Clinical Oncology 2023年第4期14卷 179-189页

作者： Ayrton I Bangolo Pierre Fwelo Chinmay Trivedi Sowmya Sagireddy Hamed Aljanaahi Auda Auda Maryama Mohamed Sonia Onyeka Miriam Fisher jyoti Thapa Erwin j Tabucanon Lyuben Georgiev Annetta Wishart Shilpee Kumari Conrad Erikson Mary Bangura Orent Paddy Rashmi Madhukar Eugenio L gomez joshua Rathod Mansi Naria Basel Hajal Mohammad Awadhalla David Siegel Harsh Parmar Noa Biran David H Vesole Pooja Phull Simcha Weissman Department of Medicine Palisades Medical CenterNorth BergenNJ 07047United States Department of Epidemiology Human Geneticsand Environmental SciencesUTHealth School of Public HealthHoustonTX 77204United States Division of Myeloma John Theurer Cancer CenterHackensackNJ 07601United States

BACKGROUND Extramedullary multiple myeloma(MM)(EMM)is a rare and aggressive subentity of MM that can be present at diagnosis or develop anytime during the disease *** is a paucity of data on the clinical characteristics and overall epidemiology of ***,there is a scarcity of data on how the interaction of age and gender influences the survival of *** To evaluate the clinical characteristics of patients with EMM over the past 2 decades and to identify epidemiologic characteristics that may impact overall *** A total of 858 patients diagnosed with EMM,between 2000 and 2017,were ultimately enrolled in our study by retrieving the Surveillance,Epidemiology,and End Results *** analyzed demographics,clinical characteristics,and overall mortality(OM)as well as cancer-specific mortality(CSM)of *** with a P value<0.1 in the univariate Cox regression were incorporated into the multivariate Cox model to determine the independent prognostic factors,with a hazard ratio(HR)of greater than 1 representing adverse prognostic *** From a sample of 858 EMM,the male gender(63.25%),age range 60-79 years(51.05%),and non-Hispanic whites(66.78%)were the most *** Nervous System and the vertebral column was the most affected site(33.10%).Crude analysis revealed higher OM in the age group 80+[HR=6.951,95%confidence interval(95%CI):3.299-14.647,P=0],Non-Hispanic Black population(HR=1.339,95%CI:1.02-1.759,P=0.036),Bones not otherwise specified(NOS)(HR=1.74,95%CI:1.043-2.902,P=0.034),and widowed individuals(HR=2.107,95%CI:1.511-2.938,P=0).Skin involvement(HR=0.241,95%CI:0.06-0.974,P=0.046)and a yearly income of$75000+(HR=0.259,95%CI:0.125-0.538,P=0)had the lowest OM in the crude *** analysis revealed higher CSM in the age group 80+,Non-Hispanic Black,Bones NOS,and *** cox proportional hazard regression analyses only revealed higher OM in the age group 80+(HR=9.792,95%CI:4.403-21.774,P=0)

关键词： Multiple myeloma Age Gender Mortality Plasmacytoma

Examination of the therapeutic potential of Delta-24-RGD in brain tumor stem cells： role of autophagic cell death

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中国神经肿瘤杂志 2007年第3期5卷 168-168页

作者： jiang H gomez-Manzano C Aoki H Alonso MM Kondo S McCormick F Xu j Kondo Y Bekele BN Colman H Lang FF Fueyo j Brain Tumor Center The University of Texas M. D. Anderson Cancer Center 1515 Holcombe Blvd Houston TX 77030 USA.

The eradication of brain tumor stem cells is essential for long-term brain tumor remission after *** this study, we examined the therapeutic potential of an oncolytic adenovirus, Deha-24-RGD, targeted to the abnormal p16INK4/Rb pathway in brain tumor stem *** brain tumor stem cell lines from surgical glioblastoma specimens expressed high levels of adenoviral receptors and allowed for efficient viral infection, replication, and oncolysis in an Rb-dependent ***-24-RGD induced autophagic cell death, as indicated by accumulation of Atg5 and LC3-Ⅱprotein and autophagic vacuoles.

关键词：治疗脑肿瘤干细胞自我吞噬作用细胞死亡

Evidence of a j/ψΛstructure and observation of excited■^(-)states in the■b^(-)→j/ψΛK^(-) decay

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Science Bulletin 2021年第13期66卷 1278-1287,M0003页

作者： R.Aaij C.Abellán Beteta T.Ackernley B.Adeva M.Adinolfi H.Afsharnia C.A.Aidala S.Aiola Z.Ajaltouni S.Akar j.Albrecht F.Alessio M.Alexander A.Alfonso Albero Z.Aliouche G.Alkhazov P.Alvarez Cartelle S.Amato Y.Amhis L.An L.Anderlini A.Andreianov M.Andreotti F.Archilli A.Artamonov M.Artuso K.Arzymatov E.Aslanides M.Atzeni B.Audurier S.Bachmann M.Bachmayer j.j.Back S.Baker P.Baladron Rodriguez V.Balagura W.Baldini j.Baptista Leite R.j.Barlow S.Barsuk W.Barter M.Bartolini F.Baryshnikov j.M.Basels G.Bassi B.Batsukh A.Battig A.Bay M.Becker F.Bedeschi I.Bediaga A.Beiter V.Belavin S.Belin V.Bellee K.Belous I.Belov I.Belyaev G.Bencivenni E.Ben-Haim A.Berezhnoy *** D.Berninghoff H.C.Bernstein C.Bertella E.Bertholet A.Bertolin C.Betancourt F.Betti Ia.Bezshyiko S.Bhasin j.Bhom L.Bian M.S.Bieker S.Bifani P.Billoir M.Birch F.C.R.Bishop A.Bizzeti M.Bj┆rn M.P.Blago T.Blake F.Blanc S.Blusk D.Bobulska j.A.Boelhauve O.Boente Garcia T.Boettcher A.Boldyrev A.Bondar N.Bondar S.Borghi M.Borisyak M.Borsato j.T.Borsuk S.A.Bouchiba T.j.V.Bowcock A.Boyer C.Bozzi M.j.Bradley S.Braun A.Brea Rodriguez M.Brodski j.Brodzicka A.Brossa Gonzalo D.Brundu A.Buonaura C.Burr A.Bursche A.Butkevich j.S.Butter j.Buytaert W.Byczynski S.Cadeddu H.Cai R.Calabrese L.Calefice L.Calero Diaz S.Cali R.Calladine M.Calvi M.Calvo gomez P.Camargo Magalhaes A.Camboni P.Campana A.F.Campoverde Quezada S.Capelli L.Capriotti A.Carbone G.Carboni R.Cardinale A.Cardini I.Carli P.Carniti L.Carus K.Carvalho Akiba A.Casais Vidal G.Casse M.Cattaneo G.Cavallero S.Celani j.Cerasoli A.j.Chadwick M.G.Chapman M.Charles Ph.Charpentier G.Chatzikonstantinidis C.A.Chavez Barajas M.Chefdeville C.Chen S.Chen A.Chernov S.-G.Chitic V.Chobanova S.Cholak M.Chrzaszcz A.Chubykin V.Chulikov P.Ciambrone M.F.Cicala X.Cid Vidal G.Ciezarek P.E.L.Clarke M.Clemencic H.V.Cliff j.Closier j.L.Cobbledick V.Coco j.A.B.Coelho j.Cogan E.Cogneras L.Cojocariu P.Collins T.Colombo L.Congedo A.Contu N.Cooke G.Coombs G.Corti C.M.Costa Sobral B.Couturier D.C.Craik j.Crkovská M.Cruz Torres R.Currie C.L.Da Silva E.Dall’ Centro Brasileiro de Pesquisas Físicas(CBPF) Rio de JaneiroBrazil Universidade Federal do Rio de janeiro(UFRj) Rio de JaneiroBrazil Center for High Energy Physics Tsinghua UniversityBeijingChina School of Physics State Key Laboratory of Nuclear Physics and Technology Peking UniversityBeijingChina University of Chinese Academy of Sciences BeijingChina Institute Of High Energy Physics(IHEP) BeijingChina Institute of Particle Physics Central China Normal UniversityWuhanHubeiChina Univ.Grenoble Alpes Univ.Savoie Mont BlancCNRSIN2P3-LAPPAnnecyFrance UniversitéClermont Auvergne CNRS/IN2P3LPCClermont-FerrandFrance Aix Marseille Univ CNRS/IN2P3CPPMMarseilleFrance UniversitéParis-Saclay CNRS/IN2P3IJCLabOrsayFrance Laboratoire Leprince-ringuet(llr) PalaiseauFrance LPNHE Sorbonne UniversitéParis Diderot Sorbonne Paris CitéCNRS/IN2P3ParisFrance I.Physikalisches Institut RWTH Aachen UniversityAachenGermany Fakultät Physik Technische Universität DortmundDortmundGermany Max-Planck-Institut für Kernphysik(MPIK) HeidelbergGermany Physikalisches Institut Ruprecht-Karls-Universität HeidelbergHeidelbergGermany School of Physics University College DublinDublinIreland INFN Sezione di Bari BariItaly INFN Sezione di Bologna BolognaItaly INFN Sezione di Ferrara FerraraItaly INFN Sezione di Firenze FirenzeItaly INFN Laboratori Nazionali di Frascati FrascatiItaly INFN Sezione di Genova GenovaItaly INFN Sezione di Milano-Bicocca MilanoItaly INFN Sezione di Milano MilanoItaly INFN Sezione di Cagliari MonserratoItaly Universita degli Studi di Padova Universita e INFNPadovaPadovaItaly INFN Sezione di Pisa PisaItaly INFN Sezione di Roma Tor Vergata RomaItaly INFN Sezione di Roma La Sapienza RomaItaly Nikhef National Institute for Subatomic Physics AmsterdamNetherlands Nikhef National Institute for Subatomic Physics and VU University Amsterdam AmsterdamNetherlands Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences KrakówPoland AGH-University of Science and Techno

First evidence of a structure in the j/ψΛinvariant mass distribution is obtained from an amplitude analysis of■b^(-)j/ψΛK^(-)*** observed structure is consistent with being due to a charmonium pentaquark with strangeness with a significance of 3.1r including systematic uncertainties and lookelsewhere *** mass and width are determined to be 4458:8±2:9t4:7-1:1 MeV and 17:3±6:5t8:0-5:7 MeV,respectively,where the quoted uncertainties are statistical and *** structure is also consistent with being due to two *** addition,the narrow excited■^(-)states,N■(1690)and■(1820),are seen for the first time in a■b^(-)decay,and their masses and widths are measured with improved *** analysis is performed using pp collision data corresponding to a total integrated luminosity of 9 fb^(-1),collected with the LHCb experiment at centre-of-mass energies of 7,8 and 13 TeV.

关键词： QCD Exotics Pentaquark Spectroscopy Quarkonium Particle and resonance production